Bioavailability of prednisolone in patients with intestinal malabsorption: the importance of measuring serum protein-binding.

abstract：BACKGROUND:Administration of insulin-like growth factor-I (IGF-I) results in selective growth of the gastrointestinal tract. We investigated the effects of IGF-I on the colonic damage induced by oral dextran sulphate sodium (DSS) in the rat. METHODS:Rats consumed 2% DSS in the drinking water for 10 days to induce coli...

journal_title：Scandinavian journal of gastroenterology

authors： Howarth GS,Xian CJ,Read LC

更新日期：1998-02-01 00:00:00

abstract：:Serum isoamylase activities were determined in patients with either cystic fibrosis (CF) or celiac disease and in age-matched healthy children by means of an inhibitory assay suitable for routine application. The percentage pancreatic isoamylase (PIA) activity was significantly decreased in CF patients when compared w...

journal_title：Scandinavian journal of gastroenterology

authors： Maillie AJ,Vaccaro MI,Calvo EL,Ruiz JA,Emiliani R,Pivetta OH

更新日期：1986-10-01 00:00:00

abstract：OBJECTIVE:The aim of this investigation was to elucidate retrospectively the therapeutic effect of infliximab in patients with active Crohn's disease (CD) under nutritional therapy. MATERIAL AND METHODS:Using a review of the clinical records in 24 nationwide institutions specializing in inflammatory bowel disease, the...

journal_title：Scandinavian journal of gastroenterology

authors： Matsumoto T,Iida M,Kohgo Y,Imamura A,Kusugami K,Nakano H,Fujiyama Y,Matsu T,Hibi T

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine which motility data of patients with noncardiac chest pain (NCCP) differ from those of controls on the basis of long-term manometry and to evaluate the coexistence of motility disorders and pathologic acid reflux. Further, motility disorders were tested as to whether th...

journal_title：Scandinavian journal of gastroenterology

authors： Adamek RJ,Wegener M,Wienbeck M,Pulte T

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:An association between alpha1-antitrypsin deficiency and chronic pancreatitis (CP) has been reported in several case reports and two systematic studies. However, conflicting results have been shown in other studies of patients with CP. All previous studies were performed by phenotyping or by measurement of s...

journal_title：Scandinavian journal of gastroenterology

authors： Witt H,Kage A,Luck W,Becker M

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:In childhood coeliac disease highly varying incidence rates have recently been disclosed. Very low incidence rates (0.09/1000) were found in Denmark, in contrast to our neighbouring country Sweden (2.93/1000). Whether this was accounted for by the diagnosis being delayed until adult life was unknown. No stud...

journal_title：Scandinavian journal of gastroenterology

authors： Bodé S,Gudmand-Høyer E

更新日期：1996-07-01 00:00:00

abstract：:We endoscoped 322 of 422 patients with end-stage renal failure undergoing maintenance dialysis treatment to determine the prevalence of erosive prepyloric changes (EPC) in uraemia. EPC grade 1 was found in 79 patients (25%), grade 2 in 16 (5%), and grade 3 in 43 (13%). EPC grades 2 and 3 were commoner among uraemic pa...

journal_title：Scandinavian journal of gastroenterology

authors： Kang JY,Wee A,Choong HL,Wu AY

更新日期：1990-07-01 00:00:00

abstract：:Autonomic nerve function was evaluated in 40 patients with total ulcerative colitis and in 25 patients with irritable bowel syndrome by three established non-invasive tests based on the heart reactions to deep breathing (E/I ratio) and tilt (acceleration and brake index). None of the patients were diabetic. Most of th...

journal_title：Scandinavian journal of gastroenterology

authors： Lindgren S,Stewenius J,Sjölund K,Lilja B,Sundkvist G

更新日期：1993-07-01 00:00:00

abstract：:Gastric blood flow has been studied endoscopically by laser Doppler flowmetry in 15 patients with chronic gastric ulcer. In all patients the ulcer was located at the lesser curvature of the corpus. The blood flow measured in this area was decreased compared with healthy controls, whereas the flow values in other parts...

journal_title：Scandinavian journal of gastroenterology

authors： Lunde OC,Kvernebo K

更新日期：1988-06-01 00:00:00

abstract：OBJECTIVES:Up to date we lack a detailed description of the colorectal endoscopic submucosal dissection (ESD) learning curve, that would represent the experience of the Western center. The aim of this study was to define the critical points of the learning curve and to draw up lesions qualification guidelines tailored ...

journal_title：Scandinavian journal of gastroenterology

authors： Spychalski M,Skulimowski A,Dziki A,Saito Y

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND/METHODS:The protective effects of trolox C (water-soluble vitamin E), vitamin C, and catalase on bromobenzene (BB)-induced toxicity to isolated rat hepatocytes were evaluated. The glutathione (GSH) content of the hepatocytes exposed to BB was measured. RESULTS:BB caused acute damage to the cells during 2 h ...

journal_title：Scandinavian journal of gastroenterology

authors： Wu J,Karlsson K,Danielsson A

更新日期：1996-08-01 00:00:00

abstract：:To elucidate potential mechanism(s) behind the mode of action of antireflux operations, the basal tone of the lower oesophageal sphincter and the relaxation after water swallows were studied before and after either a total fundic wrap (n = 25), highly selective vagotomy combined with fundoplication (n = 38), or insert...

journal_title：Scandinavian journal of gastroenterology

authors： Lundell L,Myers JC,Jamieson GG

更新日期：1993-08-01 00:00:00

abstract：:Gastrointestinal bleeding prophylaxis is well known in patients admitted to intensive care units, but only a few reports have analyzed this problem in patients admitted to a general hospital ward. In a previous study we demonstrated that close to 20% of such seriously ill placebo-treated patients bled. We conducted a ...

journal_title：Scandinavian journal of gastroenterology

authors： Grau JM,Casademont J,Fernández-Solá J,Cardellach F,Urbano-Márquez A

更新日期：1993-03-01 00:00:00

abstract：:A systematic approach is outlined for the preparation of a whole series of immunoreactive 125I-labeled gastrointestinal regulatory peptides with high specific radioactivities. In our hands, the theoretically superior Iodo-gen method has no more to offer than the harsher chloramine-T method in the iodination of secreti...

journal_title：Scandinavian journal of gastroenterology

authors： Burhol PG,Jorde R,Florholmen J,Jenssen TG,Vonen B

更新日期：1985-05-01 00:00:00

abstract：OBJECTIVE:The lack of novel therapeutic targets poses the major challenge to prolong survival and improve the quality of life for esophageal squamous cell carcinoma (ESCC). Methylenetetrahydrofolate dehydrogenase 1-like (MTHFD1L) plays critical roles in folate cycle maintenance. However, little information is available...

journal_title：Scandinavian journal of gastroenterology

authors： Yang YS,Yuan Y,Hu WP,Shang QX,Chen LQ

更新日期：2018-05-01 00:00:00

abstract：:Rectal mucosal biopsies of 13 patients suffering from ulcerative colitis, 7 patients presenting symptomatology typical of irritable colon, and 7 control persons were studied by the recently introduced glyoxylic-acid-induced fluorescence histochemical method. In ulcerative colitis, compared to control specimens: 1) the...

journal_title：Scandinavian journal of gastroenterology

authors： Kyösola K,Penttilä O,Salaspuro M

更新日期：1977-01-01 00:00:00

abstract：:Biopsy specimens from long-standing ulcerative colitis were frozen shortly after resection and homogenized before measurement of lactate dehydrogenase (LD) isoenzymes by agar electrophoresis. Results were related to histological changes in inflammation or dysplasia. The percentage of total LD M monomers was significan...

journal_title：Scandinavian journal of gastroenterology

authors： Vatn MH,Tjora S,Elgjo K,Norheim A,Bergan A

更新日期：1985-10-01 00:00:00

abstract：:Non-ulcer dyspepsia (NUD) is defined as dyspepsia in which investigation shows no evidence of focal gastroduodenal disease or oesophagitis. The aim of the present study was to determine the proportion of NUD patients with other identifiable diseases. We interviewed 327 consecutive patients who had at least 1 month of ...

journal_title：Scandinavian journal of gastroenterology

authors： Talley NJ,Piper DW

更新日期：1985-09-01 00:00:00

abstract：:Forty-eight patients with symptomatic duodenal ulcer were randomized to 4 weeks' treatment with cimetidine, 1 g/day (C4), or 1 week of cimetidine treatment followed by 3 weeks of placebo (C1 + P). The study was performed double blind. The symptoms were recorded daily on a visual analogue scale. Endoscopy was performed...

journal_title：Scandinavian journal of gastroenterology

authors： Johannessen T,Kristensen P,Fjøsne U,Hafstad PE,Kleveland PM,Løge I,Sandbakken P,Petersen H

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:We wanted to investigate the influence of viral genotype on the severity of liver injury and response to interferon and whether the level of viremia differs in accordance with genotype, severity of liver disease, and response to interferon in patients with hepatitis C virus (HCV) infection. METHODS:We studi...

journal_title：Scandinavian journal of gastroenterology

authors： Fernández I,Castellano G,Domingo MJ,Fuertes A,Colina F,Canga F,de la Cruz FJ,de la Cámara AG,Solís JA

更新日期：1997-01-01 00:00:00

abstract：:The aim of our study was to determine peripheral bone mineral content (BMC) and serum osteocalcin (OC) levels in two groups of patients with fatty liver and hepatic cirrhosis as compared with a control group comprising healthy subjects. Group I consisted of 18 male patients (mean age, 51 years) with hepatic steatosis,...

journal_title：Scandinavian journal of gastroenterology

authors： Resch H,Pietschmann P,Krexner E,Woloszczuk W,Willvonseder R

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Patients with coeliac disease have low bone mineral density (BMD), but the underlying mechanisms are unclear. Our aim was to study circulating insulin-like growth factor I (IGF-I) and its possible relationship to BMD in adults with untreated coeliac disease and after 1 year on a gluten-free diet. METHODS:In...

journal_title：Scandinavian journal of gastroenterology

authors： Valdimarsson T,Arnqvist HJ,Toss G,Järnerot G,Nyström F,Ström M

更新日期：1999-09-01 00:00:00

abstract：:Five cats were provided with a gastric fistula (GF) and a Heidenhain pouch (HP), and the proximal small intestine was excluded and provided with a duodenal fistula. A protein-rich meal, introduced into the duodenum (duodenal feeding) caused no serum gastrin increase, which supports our previous conclusion that duodena...

journal_title：Scandinavian journal of gastroenterology

authors： Fernström M,Nilsson G,Emås S

更新日期：1984-01-01 00:00:00

abstract：:Jejunal biopsy specimens from coeliac patients who had received small, oral doses (100-1500 mg) of a peptic-tryptic gluten digest were analysed by morphometric methods. An increase in the total number of surface epithelial lymphocytes, maximal at 12 h after challenge, was dose-dependent, the mean percentage rise at th...

journal_title：Scandinavian journal of gastroenterology

authors： Leigh RJ,Marsh MN,Crowe P,Kelly C,Garner V,Gordon D

更新日期：1985-08-01 00:00:00

abstract：OBJECTIVE:There is evidence for the long-term safety of oats as part of a gluten-free diet in coeliac disease (CD). Oats is generally processed by kilning, which theoretically may change its antigenic properties and be the reason that it is tolerated by patients with CD. The aim of this study was to investigate the sui...

journal_title：Scandinavian journal of gastroenterology

authors： Kemppainen TA,Heikkinen MT,Ristikankare MK,Kosma VM,Sontag-Strohm TS,Brinck O,Salovaara HO,Julkunen RJ

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The scope of self-medication is increasing in many countries, and drugs for dyspepsia are a popular group for deregulative activities. This study investigated what kind of upper gastrointestinal symptoms people self-medicate and how appropriate this self-medication is. METHODS:An anonymous questionnaire was...

journal_title：Scandinavian journal of gastroenterology

authors： Sihvo S,Hemminki E

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:This is a retrospective study of 32 consecutive patients referred in the period 1992-2000 for management of serious bile duct injuries caused by elective laparoscopic cholecystectomy. METHODS:The patients were referred on median 29 days (0 days to 34 months). Only 7 patients were referred immediately after ...

journal_title：Scandinavian journal of gastroenterology

authors： Mathisen O,Søreide O,Bergan A

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVES:Intraoperative colonoscopy (IC) is routinely used in colorectal surgery procedures, both oncologic and benign ones. Despite its extensive use there is a lack of literature addressing this important issue. The aims of this paper are to determine the contributions of this tool, especially considering changes i...

journal_title：Scandinavian journal of gastroenterology

authors： Cerdán Santacruz C,Esteban López-Jamar JM,Sánchez López E,Cerdán Miguel J

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:While marked changes in the frequency of hepatobiliary malignancies, most notably hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC), have been observed in different populations, no such data have been reported for Germany. We aimed to provide epidemiological data on recent trends in liv...

journal_title：Scandinavian journal of gastroenterology

authors： von Hahn T,Ciesek S,Wegener G,Plentz RR,Weismüller TJ,Wedemeyer H,Manns MP,Greten TF,Malek NP

更新日期：2011-09-01 00:00:00

abstract：:Understanding the physiology of gastroesophageal junction (GEJ) is important as failure of its function is associated with reflux disease, hiatus hernia, and cancer. In recent years, there have been impressive developments in high resolution technologies allowing measurement of luminal pressure, pH, and impedance. One...

journal_title：Scandinavian journal of gastroenterology

authors： Lee YY,Whiting JG,Robertson EV,Derakhshan MH,Smith D,McColl KE

更新日期：2013-04-01 00:00:00