Gastric blood flow in patients with gastric ulcer measured by endoscopic laser Doppler flowmetry.

Abstract:

:Gastric blood flow has been studied endoscopically by laser Doppler flowmetry in 15 patients with chronic gastric ulcer. In all patients the ulcer was located at the lesser curvature of the corpus. The blood flow measured in this area was decreased compared with healthy controls, whereas the flow values in other parts of the stomach were similar to those of controls. In the ulcer bed very low blood flow values were measured. The blood flow of the ulcer margin was similar to that of other parts of the lesser curvature. After 4-6 weeks' treatment with the H2-receptor antagonist cimetidine, the ulcer was healed in about 70% of the patients. The blood flow measured at the lesser curvature and in the ulcer area was still low and of the same magnitude as the corresponding values of the first measurement. After 4 months the ulcer was healed in all but one patient. The blood flow of the lesser curvature had increased significantly, whereas decreased blood flow was measured at the distal part of the greater curvature. In the area where the ulcer was located, very low flow values were still measured. This finding may explain why ulcer recurrence usually occurs at the site of the primary ulcer.

journal_name

Scand J Gastroenterol

authors

Lunde OC,Kvernebo K

doi

10.3109/00365528809093909

subject

Has Abstract

pub_date

1988-06-01 00:00:00

pages

546-50

issue

5

eissn

0036-5521

issn

1502-7708

journal_volume

23

pub_type

杂志文章
  • Reversibility of the cell kinetic changes induced by omeprazole in the rat oxyntic mucosa. An autoradiographic study using tritiated thymidine.

    abstract::Both oxyntic mucosal progenitor cells and enterochromaffin-like (ECL) cells are under the trophic control of gastrin. We studied the effect of discontinuing omeprazole-induced hypergastrinemia on cell proliferation and ECL cell function in the rat oxyntic mucosa. All rats had hypergastrinemia after 16 days' omeprazole...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529209165437

    authors: Tielemans Y,Chen D,Sundler F,Håkanson R,Willems G

    更新日期:1992-01-01 00:00:00

  • Effects of atropine on GIP-induced insulin and pancreatic polypeptide release in man.

    abstract::Eight fasting students were given an infusion of porcine gastric inhibitory polypeptide (GIP) and glucose with or without atropine on two separate days. Mean serum insulin levels increased significantly and similarly on both occasions, indicating that both the glucose- and GIP-induced insulin release is unaffected by ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.3109/00365528509091658

    authors: Amland PF,Jorde R,Burhol PG,Giercksky KE

    更新日期:1985-04-01 00:00:00

  • No support for endoscopic surveillance for gastric cancer in hereditary non-polyposis colorectal cancer.

    abstract:BACKGROUND:The DNA mismatch repair gene mutations underlying hereditary non-polyposis colorectal cancer syndrome (HNPCC) also predispose, besides colorectal and endometrial cancer, to gastric cancer. usually of the intestinal type. The carcinogenetic pathway behind the elevated gastric cancer risk is largely unknown. ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520252903134

    authors: Renkonen-Sinisalo L,Sipponen P,Aarnio M,Julkunen R,Aaltonen LA,Sarna S,Järvinen HJ,Mecklin JP

    更新日期:2002-05-01 00:00:00

  • Objective assessment of the contribution of each diagnostic test and of the ordering sequence in jaundice caused by pancreatobiliary carcinoma.

    abstract:BACKGROUND:Computer-assisted diagnostic systems are not substantially more accurate than the clinician in the differential diagnosis of jaundice but may help in optimal selection and sequencing of tests. The present study aimed to assess with an electronic diagnostic tool the pattern of ordering tests and the diagnosti...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655200750024038

    authors: de Bree E,Tsiftsis DD,Santos RM,Lavelle SM,Cuervas-Mons V,Gauthier A,Gips C,Malchow-Moeller A,Molino G,Rohr G,Theodossi A,Tsantoulas D

    更新日期:2000-04-01 00:00:00

  • Detection of naproxen-induced intestinal permeability change may be facilitated by adding a standardized meal but not by forming marker ratios.

    abstract:BACKGROUND:We recently compared the intestinal permeability markers polysucrose (PS) 15,000, 51Cr-ethylenediaminetetraacetic acid (EDTA), and 14C-mannitol in healthy humans. We have now studied the ability of these markers to show non-steroidal anti-inflammatory drug (NSAID)-induced intestinal damage, with special rega...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529609036908

    authors: Oman H,Henriksson AE,Johansson SG,Blomquist L

    更新日期:1996-12-01 00:00:00

  • A non-invasive fibrosis score predicts treatment outcome in chronic hepatitis C virus infection.

    abstract:OBJECTIVE:The results of a previous study suggest that an index calculated according to the formula (normalized ASAT x PK-INR) x 100/thrombocyte count (x 10(9)/L; GUCI) may reflect liver fibrosis in patients with chronic hepatitis C virus (HCV) infection. The aims of the present study were (i) to validate the associati...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520701514461

    authors: Westin J,Ydreborg M,Islam S,Alsiö A,Dhillon AP,Pawlotsky JM,Zeuzem S,Schalm SW,Ferrari C,Neumann AU,Hellstrand K,Lagging M,DITTO-HCV Study Group.

    更新日期:2008-01-01 00:00:00

  • High frequency of parasitic and viral stool pathogens in patients with active ulcerative colitis: report from a tropical country.

    abstract:OBJECTIVE:Diarrhoeal relapses in patients with ulcerative colitis (UC) may be associated with enteric infections and its diagnosis may lessen avoidable exposure to corticosteroids and/or immunosuppressants. The purpose of this study was to assess the frequency of stool pathogens (parasitic and viral) in patients with a...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520802556809

    authors: Banerjee D,Deb R,Dar L,Mirdha BR,Pati SK,Thareja S,Falodia S,Ahuja V

    更新日期:2009-01-01 00:00:00

  • Contribution of intraoperative colonoscopy in a colorectal surgery unit.

    abstract:OBJECTIVES:Intraoperative colonoscopy (IC) is routinely used in colorectal surgery procedures, both oncologic and benign ones. Despite its extensive use there is a lack of literature addressing this important issue. The aims of this paper are to determine the contributions of this tool, especially considering changes i...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2017.1362465

    authors: Cerdán Santacruz C,Esteban López-Jamar JM,Sánchez López E,Cerdán Miguel J

    更新日期:2017-11-01 00:00:00

  • Anti-CagA and anti-VacA antibodies in Helicobacter pylori-infected patients with and without peptic ulcer disease in Serbia and Montenegro.

    abstract:BACKGROUND:The expression of two Helicobacter pylori proteins, CagA and VacA, is associated with more severe pathogenesis and clinical outcomes of the infection. However, this association varies among geographical regions and ethnic groups. We therefore evaluated CagA and VacA seroprevalence in H. pylori-positive dyspe...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520310008403

    authors: Sokic-Milutinovic A,Wex T,Todorovic V,Milosavljevic T,Malfertheiner P

    更新日期:2004-03-01 00:00:00

  • Incidence, diagnostic, treatment and outcome of patients diagnosed with cancer of the pancreas during 1986-2009: a population-based study.

    abstract:OBJECTIVE:Limited data exist on the changes in the epidemiology of pancreatic cancer and outcomes over the last decades in population-based cohorts. We aimed to compare the incidence of pancreatic cancer, diagnostic, treatment and survival among patients diagnosed over the period 1986-2009. MATERIALS AND METHODS:A ret...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2017.1390598

    authors: Jonsdottir SB,Juliusson G,Kristinsson JÖ,Hreinsson JP,Jonasson JG,Björnsson ES

    更新日期:2018-01-01 00:00:00

  • Magnetic resonance imaging of the small bowel in Crohn's disease.

    abstract:OBJECTIVE:There may be advantages in using magnetic resonance imaging (MRI) in small-bowel disease. The aims of this study were to optimize the MRI examination technique and to evaluate the capabilities of MRI compared with those of conventional enteroclysis (CE). MATERIALS AND METHODS:MRI and CE were performed in 36 ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1080/00365520510015683

    authors: Frøkjaer JB,Larsen E,Steffensen E,Nielsen AH,Drewes AM

    更新日期:2005-07-01 00:00:00

  • The changing histological pattern of gastric polyps in an ethnically heterogeneous population.

    abstract:BACKGROUND AND AIM:Variation in the prevalence of various types of gastric polyps worldwide may reflect different etiologies. Here, the authors report the dynamic changes in histological distribution of gastric polyps over time and by ethnicity for individuals who underwent gastroscopies between 1994 and 2009 at two ho...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2012.682091

    authors: Peretz A,Fuchs T,Livovsky DM,Turvall E,Pappo O,Ackerman Z

    更新日期:2012-09-01 00:00:00

  • Small-bowel mucosal inflammation in reticulin or gliadin antibody-positive patients without villous atrophy.

    abstract:BACKGROUND:We investigated whether individuals with positive coeliac disease antibodies but without small-bowel villous atrophy have mucosal inflammation implicating gluten-sensitivity. METHODS:Small-bowel mucosal morphology; CD3+, alphabeta+, and gammadelta+ T-cell receptor-bearing intraepithelial lymphocytes; and mu...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655298750026967

    authors: Kaukinen K,Collin P,Holm K,Karvonen AL,Pikkarainen P,Mäki M

    更新日期:1998-09-01 00:00:00

  • Effect of indomethacin on blood flow distribution in the stomach of cats with acute gastric ulcer.

    abstract::An ulcer was induced in the anterior wall of the antrum of cats by local injection of acetic acid solution. Carbonized microspheres, 15 +/- microns in diameter, labelled with 141Ce, 46Sc, and 85Sr, were used to measure blood flow in different regions and layers of the stomach wall. The radioactivity of a blood referen...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Skarstein A

    更新日期:1979-01-01 00:00:00

  • Role of gender upon basal and postprandial systemic and splanchnic haemodynamics in humans.

    abstract:BACKGROUND:Food intake, accompanied by systemic and splanchnic haemodynamic changes, has only been studied in males. The extent to which splanchnic postprandial hyperaemia shows gender differences is unknown. METHODS:We tested 1) the splanchnic hyperaemic response to food in females and 2) whether postprandial haemody...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655201750153458

    authors: Szinnai C,Mottet C,Gutzwiller JP,Drewe J,Beglinger C,Sieber CC

    更新日期:2001-05-01 00:00:00

  • Phenotypic variance in childhood coeliac disease and the HLA-DQ/DR dose effect.

    abstract:OBJECTIVE:Coeliac disease (CD) is associated with HLA-DQ2 and DQ8. The clinical picture is variable and certain human leucocyte antigen (HLA) DQ/DR combinations have a higher relative risk (RR) for CD than others. Moreover, the HLA-DQ gene-dose effect has an impact on the strength of the gluten-specific T-cell response...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520802116422

    authors: Vermeulen BA,Hogen Esch CE,Yuksel Z,Koning F,Verduijn W,Doxiadis II,Schreuder GM,Mearin ML

    更新日期:2009-01-01 00:00:00

  • Electrogenic transport of glucose in the normal upper duodenum. I. Technique and apparent transport constants.

    abstract::We investigated the electrogenic transport of glucose in the upper part of the duodenum in 11 healthy subjects by means of simultaneous intestinal perfusion of test solutions and measurement of the corresponding potential differences between blood and the duodenal lumen. The technique entailed continuous perfusion and...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Sparsø BH,Luke M,Wium E

    更新日期:1984-06-01 00:00:00

  • Increased serum levels of vascular endothelial growth factor in patients with inflammatory bowel disease.

    abstract:BACKGROUND:Vascular endothelial growth factor (VEGF) is a potent angiogenic, vascular permeability-enhancing, and calcium-dependent enzyme-modulating cytokine with overexpression in various pathologic disorders, including granulomatous inflammation, tissue repair, delayed hypersensitivity reactions, rheumatoid arthriti...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.1080/00365529850172070

    authors: Griga T,Tromm A,Spranger J,May B

    更新日期:1998-05-01 00:00:00

  • Predictors of heavy drinking after liver transplantation for alcoholic liver disease in Denmark (1990-2013): a nationwide study with competing risks analyses.

    abstract:OBJECTIVE:Heavy drinking following liver transplantation decreases survival. Little is known of predictors of heavy drinking, which should guide clinicians identifying patients at high risk of return to heavy drinking after transplantation. MATERIAL AND METHODS:We calculated the cumulative incidence of heavy drinking ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2015.1067903

    authors: Askgaard G,Tolstrup JS,Gerds TA,Hamberg O,Zierau L,Kjær MS

    更新日期:2016-01-01 00:00:00

  • Patients and gastroenterologists' perceptions of treatments for inflammatory bowel diseases: do their perspectives match?

    abstract:BACKGROUND:Perceptions of appropriateness of treatments may differ between gastroenterologists (GIs) and inflammatory bowel disease (IBD) patients. The aim of this study was to explore and compare GIs' and patients' perceptions of risks and benefits of treatments and prioritization of expected outcomes. METHODS:Four v...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2016.1147065

    authors: Vaucher C,Maillard MH,Froehlich F,Burnand B,Michetti P,Pittet V

    更新日期:2016-09-01 00:00:00

  • Helicobacter pylori-associated gastritis and dyspepsia. The influence on migrating motor complexes.

    abstract::Twenty-five patients with dyspepsia were included. In 19 patients with a median age of 48 (range, 20-72) years endoscopy and histologic examination of biopsy specimens from the antrum and corpus of the stomach showed Helicobacter pylori-positive gastritis as the only pathologic finding. In six patients with a median a...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529409090451

    authors: Qvist N,Rasmussen L,Axelsson CK

    更新日期:1994-02-01 00:00:00

  • Short stricture of the rectum regressing on discontinuation of hormone replacement therapy: endoscopic appearance, multiple biopsies and clinical improvement insufficient for diagnosis.

    abstract::A short, benign-looking stricture of the rectum presented itself clinically as subileus in a middle-aged woman after 5 years on hormone replacement therapy (HRT) and 8 years after curative surgery for cancer of the ovaries. Radiological work-up and multiple, repeated biopsies supported the endoscopically appearing ben...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520510011614

    authors: Hoff G,Wiig J,Reed W,Hole KH,Scheistrøen M,Henriksen H

    更新日期:2005-03-01 00:00:00

  • Quantitative measurement of nitric oxide and hydrogen peroxide in Helicobacter pylori-infected Mongolian gerbils in vivo.

    abstract:OBJECTIVE:Peroxynitrite formation, as reflected by nitrotyrosine expression, is low in Helicobacter pylori-infected Mongolian gerbils despite pronounced expression of radical-forming enzymes. The aim of the present study was to investigate in vivo whether H. pylori inhibits either one or both of the nitro- and oxyradic...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520701288306

    authors: Elfvin A,Edebo A,Bölin I,Fändriks L

    更新日期:2007-10-01 00:00:00

  • Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial.

    abstract::OBJECTIVE. Meta-analyses have indicated effect of probiotics on irritable bowel syndrome (IBS). However, few long-term trials have been conducted and uncertainty remains as to effectiveness and long-term effect in a primary care setting. We aimed to investigate the effect of probiotics compared with placebo in the man...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.3109/00365521.2013.825314

    authors: Begtrup LM,de Muckadell OB,Kjeldsen J,Christensen RD,Jarbøl DE

    更新日期:2013-10-01 00:00:00

  • Gastric cancer confined to the muscularis propria: a possible candidate for laparoscopic surgery or adjuvant therapy.

    abstract:OBJECTIVE:Gastric cancer confined to the muscularis propria (mp) has a favorable prognosis, but still belongs to the advanced category. Many oncologists have difficulties in selecting treatment modalities owing to the confused situation of mp cancer. To clarify the therapeutic strategy, the clinicopathological characte...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520410009302

    authors: Park SS,Kim CS,Mok YJ,Kim SJ,Kim HI

    更新日期:2005-04-01 00:00:00

  • Prognostic factors and outcomes of patients with hepatocellular carcinoma in non-cirrhotic liver.

    abstract:OBJECTIVES:To report the outcome of patients with hepatocellular carcinoma (HCC) in non-cirrhotic liver depending on the mode of primary treatment and to define clinicopathological factors influencing patients' prognosis. METHODS:A retrospective analysis of an unselected cohort of 105 patients was performed. Overall s...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2012.677952

    authors: Wörns MA,Bosslet T,Victor A,Koch S,Hoppe-Lotichius M,Heise M,Hansen T,Pitton MB,Niederle IM,Schuchmann M,Weinmann A,Düber C,Galle PR,Otto G

    更新日期:2012-06-01 00:00:00

  • Phenol toxicity and conjugation in human colonic epithelial cells.

    abstract:BACKGROUND:Colonic epithelial cells are exposed to a range of potentially harmful luminal factors. including phenols, but it is unresolved whether these compounds impair the integrity of the epithelium. The aim of this study was to describe the effect of phenol exposure on human colonic epithelial cells in vitro and th...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655202753387392

    authors: Pedersen G,Brynskov J,Saermark T

    更新日期:2002-01-01 00:00:00

  • Health care costs associated with Australian tertiary inflammatory bowel disease care.

    abstract:INTRODUCTION:We aimed to describe the total costs of illness for IBD patients and compare the costs of patients with active disease to those with inactive disease. MATERIALS AND METHODS:Resource use for IBD management was itemized for attributable costs (AUD) among all IBD patients over a 12-month period at an Austral...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2017.1323117

    authors: Jackson B,Con D,Ma R,Gorelik A,Liew D,De Cruz P

    更新日期:2017-08-01 00:00:00

  • Invasive and non-invasive diagnosis of Helicobacter pylori-associated atrophic gastritis: a comparative study.

    abstract:OBJECTIVE:Helicobacter pylori-associated atrophic gastritis is known to be a significant risk factor for gastric cancer. Among the well-known parameters of atrophic gastritis are the levels of serum gastrin-17 (G-17) and pepsinogen I (PG1), which are biomarkers of gastric antral and corpus mucosal activity, respectivel...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520410010607

    authors: Pasechnikov VD,Chukov SZ,Kotelevets SM,Mostovov AN,Mernova VP,Polyakova MB

    更新日期:2005-03-01 00:00:00

  • Percutaneous ethanol injection in the treatment of hepatocellular carcinoma. A multicenter survey of evaluation practices and complication rates.

    abstract:BACKGROUND:Percutaneous ethanol injection (PEI) has become a widely used procedure in the treatment of hepatocellular carcinoma (HCC). However, the criteria for selecting patients are not standardized, and little information is available about the complications of the procedure. METHODS:A questionnaire was sent to 11 ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529709002998

    authors: Di Stasi M,Buscarini L,Livraghi T,Giorgio A,Salmi A,De Sio I,Brunello F,Solmi L,Caturelli E,Magnolfi F,Caremani M,Filice C

    更新日期:1997-11-01 00:00:00