Effect of mental stress and cisapride on autonomic nerve functions in functional dyspepsia.

Abstract:

BACKGROUND:Disordered autonomic nerve function is frequently present in patients with functional dyspepsia (FD). In this study we investigated whether the prokinetic cisapride, which acts via acetylcholine receptors, and stress may modulate these abnormalities. METHODS:Nineteen patients (6 men, 13 women) with FD and 10 healthy subjects (3 men, 7 women) were studied after 3 days' treatment with 10 mg cisapride three times daily and placebo in a crossover design. Mental stress was induced with a videogame. Sympathetic and vagal nerve functions were assessed noninvasively by skin conductance and respiratory sinus arrhythmia, respectively. RESULTS:Vagal tone was significantly lower in FD patients than in controls both before and after mental stress (P < 0.001). Sympathetic tone was higher in patients with FD than in controls (P < 0.03). Generally, stress scores were increased by mental stress in both groups (P < 0.001). In FD patients, but not in controls, cisapride significantly increased the sympathetic tone both before (P < 0.05) and after stress (P < 0.05). CONCLUSIONS:Patients with FD have lower vagal tone and higher sympathetic tone than healthy controls. Treatment with cisapride increased sympathetic tone in the patient group but had no effect on vagal tone.

journal_name

Scand J Gastroenterol

authors

Hveem K,Svebak S,Hausken T,Berstad A

doi

10.1080/00365529850166824

subject

Has Abstract

pub_date

1998-02-01 00:00:00

pages

123-7

issue

2

eissn

0036-5521

issn

1502-7708

journal_volume

33

pub_type

临床试验,杂志文章,随机对照试验
  • Effects of inhibition of PAF, ICAM-1 and PECAM-1 on gut barrier failure caused by intestinal ischemia and reperfusion.

    abstract:BACKGROUND:The role of cell adhesion molecules and transmigration of PMNs through the endothelial barrier is probably essential in intestinal ischemia and reperfusion (I/R)-induced gut barrier dysfunction. Although cytokines are released in I/R, it is unclear whether cytokines directly increase permeability or if this ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520150218066

    authors: Sun Z,Wang X,Lasson A,Böjesson A,Annborn M,Andersson R

    更新日期:2001-01-01 00:00:00

  • Epidemiology and causes of death in a Swedish cohort of patients with autoimmune hepatitis.

    abstract:BACKGROUND:Epidemiological studies of autoimmune hepatitis (AIH) show varying figures on prevalence and incidence, and data on the long-term prognosis are scarce. Objective To investigate the epidemiology, long-term prognosis and causes of death in a Swedish AIH cohort. MATERIAL AND METHODS:Data collected from 634 AIH...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2017.1335772

    authors: Danielsson Borssén Å,Marschall HU,Bergquist A,Rorsman F,Weiland O,Kechagias S,Nyhlin N,Verbaan H,Nilsson E,Werner M

    更新日期:2017-09-01 00:00:00

  • Pancreatic duct changes are not associated with early signs of chronic pancreatitis at magnetic resonance imaging (MRI) in patients with primary sclerosing cholangitis.

    abstract:OBJECTIVE:The association between chronic pancreatitis (CP) and primary sclerosing cholangitis (PSC) has been reported previously. The aims of the present study were to evaluate the presence of early pancreatic abnormalities and duct changes, using MRCP/MRI in PSC and to evaluate possible risk factors for these changes...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521003793741

    authors: Said K,Albiin N,Lindberg B,Brismar TB,Karrar A,Permert J,Bergquist A

    更新日期:2010-08-01 00:00:00

  • Efficacy and safety profile of calcineurin inhibitor salvage therapy in autoimmune hepatitis.

    abstract:BACKGROUND:As data is limited on the outcomes of calcineurin inhibitors (CNI) in autoimmune hepatitis (AIH), we evaluated the efficacy and safety of CNI in AIH patients who failed prior treatment(s). METHODS:A retrospective study was performed of AIH patients who received cyclosporine A (CsA) and/or tacrolimus (TAC) a...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2020.1821764

    authors: Roberts SK,Strasser SI,Nicoll AJ,Kemp W,Majeed A,Mitchell J,Stuart K,Gow P,Sood S,MacQuillan G,George J,Mitchell J,McCaughan GW,ALA Clinical Research Network.

    更新日期:2020-11-01 00:00:00

  • Is levofloxacin-based triple therapy an alternative for first-line eradication of Helicobacter pylori? A systematic review and meta-analysis.

    abstract:OBJECTIVES:To evaluate the available data on the efficacy and safety of levofloxacin-based triple therapy compared with standard triple therapy in first-line treatment for Helicobacter pylori infection. METHODS:By searching MEDLINE, The Cochrane Central Register of Controlled Trials, and Web of Knowledge, two independ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,meta分析,评审

    doi:10.3109/00365521.2014.887765

    authors: Xiao SP,Gu M,Zhang GX

    更新日期:2014-05-01 00:00:00

  • Comparison of 5-aminosalicylic acid (3 g) and prednisolone phosphate sodium enemas (30 mg) in the treatment of distal ulcerative colitis. A prospective, randomized, double-blind trial.

    abstract::Twenty-nine patients with attacks of distal ulcerative colitis were treated randomly with 3 g 5-aminosalicylic acid (5-ASA) or 30 mg of prednisolone phosphate sodium (PP) enemas (40 ml). Endoscopic, clinical, and histologic improvement were comparable in the two treatment groups. Our study showed that topical treatmen...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00365528809090161

    authors: Mulder CJ,Tytgat GN,Wiltink EH,Houthoff HJ

    更新日期:1988-10-01 00:00:00

  • Effect of glucagon-like peptide-1 on gastric somatostatin and gastrin secretion in the rat.

    abstract::The effect of glucagon-like peptide-1 (GLP-1) amide on gastric somatostatin and gastrin secretion was investigated in the isolated, vascularly perfused rat stomach preparation. GLP-1 (7-36) amide, 10(-12) to 10(-7)M, dose-dependently increased gastric somatostatin release, achieving maximal stimulation (314 +/- 15% ab...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529009095514

    authors: Eissele R,Koop H,Arnold R

    更新日期:1990-05-01 00:00:00

  • Cimetidine on-demand in dyspepsia. Experience with randomized controlled single-subject trials.

    abstract::Double-blind randomized controlled trials in single subjects (N of 1 RCTs) have demonstrated a beneficial symptomatic effect of cimetidine in reflux- or ulcer-like non-ulcer dyspepsia (NUD). However, spontaneous fluctuations in symptoms reduce the validity of such trials when performed as continuous trials with fixed ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00365529208999947

    authors: Johannessen T,Petersen H,Kristensen P,Fosstvedt D,Kleveland PM,Dybdahl J,Løge I

    更新日期:1992-01-01 00:00:00

  • Usefulness and limitations of transabdominal ultrasonography for detecting small-bowel tumors.

    abstract:OBJECTIVE:New methods of examining the small bowel, e.g. capsule endoscopy (CE) and double-balloon endoscopy (DBE), have recently been developed. Transabdominal ultrasonography (TUS) is a conventional, non-invasive, and less-expensive modality. The aim of this study was to evaluate the usefulness and limitations of TUS...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520802495578

    authors: Fukumoto A,Tanaka S,Imagawa H,Shishido T,Oka S,Yoshida S,Yamada H,Chayama K

    更新日期:2009-01-01 00:00:00

  • Analysis of direct medical care costs of peptic ulcer disease in a Korean tertiary medical center.

    abstract:OBJECTIVES:There have been no reported data on the medical care cost of idiopathic peptic ulcer disease (PUD) compared with H. pylori (+) and/or NSAID (+) cases although H. pylori-negative idiopathic ulcers are increasing. The aim of this study was to investigate the direct medical care costs of PUD based on whether it...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2011.639083

    authors: Kang JM,Seo PJ,Kim N,Lee BH,Kwon J,Lee DH,Jung HC

    更新日期:2012-01-01 00:00:00

  • The relationship between p27(kip1) expression and the change of radiosensitivity of esophageal carcinoma cells.

    abstract:OBJECTIVE:Radioresistance is considered the main reason for therapeutic failure in radiotherapy of esophageal carcinoma. However, the underlying mechanisms of radioresistance remain elusive. The purpose of this study was to investigate the relationship between p27(kip1) expression and the change of radiosensitivity of ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2010.522721

    authors: Tong Q,Zhang W,Jin S,Li S,Chen Z

    更新日期:2011-02-01 00:00:00

  • Helicobacter pylori DNA isolation in the stool: an essential pre-requisite for bacterial noninvasive molecular analysis.

    abstract:PURPOSE:Real-time polymerase chain reaction (RT-PCR) is a widely used technique for bacterial and viral infection diagnosis. Herein, we report our preliminary experience in retrieving H. pylori genetic sequences in stools and analyzing genotypic clarithromycin resistance by RT-PCR (noninvasive), with the aim of compari...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2016.1216592

    authors: Giorgio F,Ierardi E,Sorrentino C,Principi M,Barone M,Losurdo G,Iannone A,Giangaspero A,Monno R,Di Leo A

    更新日期:2016-12-01 00:00:00

  • Idiosyncratic drug allergic phenprocoumon-induced hepatitis with subacute liver failure initially misdiagnosed as autoimmune hepatitis.

    abstract:BACKGROUND:Coumarin anticoagulants are known to cause hepatotoxicity, but only a few cases have been reported. Coumarins are usually administered following cardiovascular surgery and the differential diagnosis is post-transfusion hepatitis. METHODS:We report the case of a 46-year-old woman who presented with jaundice,...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655201300192076

    authors: Hinrichsen H,Lüttges J,Klöppel G,Fölsch UR,Schmidt WE

    更新日期:2001-07-01 00:00:00

  • Total colectomy, mucosal proctectomy, and an ileal reservoir to an anal anastomosis. A comparison of short and long efferent legs.

    abstract::In a consecutive series of 46 possible candidates for total colectomy, mucosal proctectomy, and ileal reservoir to an anal anastomosis, we have compared the clinical outcome of group I, with a long efferent leg (12 cm), and group II, with a short efferent leg (3-5 cm). The surgical procedure was done in three steps: f...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528509088877

    authors: Hansen LK,Olsen PR,Simonsen L

    更新日期:1985-11-01 00:00:00

  • Response to jejunal acidification in man. I. Changes in composition of perfusate.

    abstract::The jejunal disposal of perfused acid was studied in 11 control subjects and 12 patients with duodenal ulcer. It was found that the capacity to dispose of acid was saturable and was less than control in patients with duodenal ulcer. When the load of acid was small, all the acid disappeared from the jejunum and sodium ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Thjodleifsson B,Wormsley KG

    更新日期:1976-01-01 00:00:00

  • Gastro-oesophageal reflux in obese subjects: influence of overweight, weight loss and chronic gastric balloon distension.

    abstract:BACKGROUND:Gastro-oesophageal reflux is an obesity-related health risk assumed to improve after weight loss. Prolonged intragastric balloon distension might oppose this. The purpose of the study was to investigate the prevalence of gastro-oesophageal reflux in untreated obese subjects and to study the consequences of w...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1080/003655202761020498

    authors: Mathus-Vliegen EM,Tygat GN

    更新日期:2002-11-01 00:00:00

  • Propofol combined with traditional sedative agents versus propofol- alone sedation for gastrointestinal endoscopy: a meta-analysis.

    abstract:OBJECTIVE:To assess the efficacy and safety of sedation of propofol combined with traditional sedative agents (PTSA) for gastrointestinal endoscopy, we conducted a meta-analysis of randomized controlled trials (RCTs) comparing PTSA with propofol-alone sedation. MATERIAL AND METHODS:RCTs comparing the effects of PTSA a...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,meta分析

    doi:10.3109/00365521.2012.737360

    authors: Wang D,Wang S,Chen J,Xu Y,Chen C,Long A,Zhu Z,Liu J,Deng D,Chen J,Tang D,Wang L

    更新日期:2013-01-01 00:00:00

  • Safety and efficacy of precut needle-knife fistulotomy.

    abstract::OBJECTIVE. Although precut is considered an useful alternative when standard methods of biliary access have failed, there is some controversy about it's safety. The study aim was to evaluate the effectiveness of needle-knife fistulotomy (NKF) after a difficult biliary cannulation and whether common bile duct (CBD) dia...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2014.898085

    authors: Lopes L,Dinis-Ribeiro M,Rolanda C

    更新日期:2014-06-01 00:00:00

  • Bacterial overgrowth in jejunal and ileal disease.

    abstract::The number of bacteria recovered in anaerobic cultures of jejunal secretions was significantly higher in a group of 10 patients with jejunal disease and stagnation of gut content in the proximal small bowel than in a group of 10 patients with similar conditions in the distal ileum. Some overlap in bacterial numbers oc...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528309181596

    authors: Bjørneklett A,Fausa O,Midtvedt T

    更新日期:1983-03-01 00:00:00

  • Necessity of multiple gastric biopsies from different sites for detection of clarithromycin-resistant Helicobacter pylori strains.

    abstract:BACKGROUND:It has been reported that approximately 10% of patients infected with Helicobacter pylori have both clarithromycin-susceptible and clathromycin-resistant strains. However, there have been no reports indicating whether only one gastric biopsy is sufficient to detect clarithromycin-resistant strains. METHODS:...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520310004731

    authors: Masuda H,Hiyama T,Yoshihara M,Tanaka S,Shimamoto F,Haruma K,Chayama K

    更新日期:2003-09-01 00:00:00

  • Evaluation of preoperative prognostic factors in patients with resectable pancreatic ductal adenocarcinoma.

    abstract::Objective: Upfront surgery is the standard treatment for resectable pancreatic ductal adenocarcinomas (R-PDACs); however, these tumors often recur. We investigated the factors governing recurrence and prognosis in patients with R-PDAC. Methods: We analyzed 359 patients who underwent upfront surgery for R-PDAC between ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2019.1624816

    authors: Izumo W,Higuchi R,Furukawa T,Yazawa T,Uemura S,Shiihara M,Yamamoto M

    更新日期:2019-06-01 00:00:00

  • The incidence and result of radiological examination of the stomach using a barium meal.

    abstract::In 1964 1.6-1.8% of the population in Copenhagen County - with a population of approx. 500,000 - were referred for a radiological examination of the stomach. The incidence, the same in both sexes, increased with increasing age, being 1% at the age of 20 years and 3-4% at the age of 70 years. The probability of demonst...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Bonnevie O

    更新日期:1976-01-01 00:00:00

  • Faecal calprotectin shedding after short-term treatment with non-steroidal anti-inflammatory drugs.

    abstract:BACKGROUND:Increased faecal calprotectin shedding indicates gastrointestinal mucosal inflammation. METHODS:We studied the effect of short-term treatment with non-steroidal anti-inflammatory drugs (NSAIDs) on faecal calprotectin shedding in two randomized crossover studies, with treatment regimens of indomethacin or na...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00365529609006407

    authors: Meling TR,Aabakken L,Røseth A,Osnes M

    更新日期:1996-04-01 00:00:00

  • The association between non-ulcer dyspepsia and other gastrointestinal disorders.

    abstract::Non-ulcer dyspepsia (NUD) is defined as dyspepsia in which investigation shows no evidence of focal gastroduodenal disease or oesophagitis. The aim of the present study was to determine the proportion of NUD patients with other identifiable diseases. We interviewed 327 consecutive patients who had at least 1 month of ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528509088842

    authors: Talley NJ,Piper DW

    更新日期:1985-09-01 00:00:00

  • Diagnostic value of endoscopy for the diagnosis of giardiasis and other intestinal diseases in patients with persistent diarrhea from tropical or subtropical areas.

    abstract:OBJECTIVE:Upper endoscopy has been suggested as a valuable tool in the diagnosis of giardiasis. The aim of this study was to compare two methods based on endoscopy, i.e. microscopy of duodenal fluid and histology, with a fluorescent-antibody assay for the detection of Giardia lamblia cysts in stool specimens. The role ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520600881193

    authors: Wahnschaffe U,Ignatius R,Loddenkemper C,Liesenfeld O,Muehlen M,Jelinek T,Burchard GD,Weinke T,Harms G,Stein H,Zeitz M,Ullrich R,Schneider T

    更新日期:2007-03-01 00:00:00

  • Solar radiation is inversely associated with inflammatory bowel disease admissions.

    abstract:OBJECTIVE:To explore the associations between latitude and solar radiation with inflammatory bowel disease admission rates in Chile, the country with the largest variation in solar radiation in the world. PATIENTS AND METHODS:This is an ecological study, which included data on all hospital-admitted population for infl...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2017.1307444

    authors: Jaime F,Riutort MC,Alvarez-Lobos M,Hoyos-Bachiloglu R,Camargo CA Jr,Borzutzky A

    更新日期:2017-01-01 00:00:00

  • Primary treatment of carcinoma of the anus by combined radiotherapy and chemotherapy.

    abstract::Twenty-four patients with carcinoma of the anus were treated with a combined regimen of external irradiation (50 Gy) and mitomycin C and 5-fluorouracil. A relatively large number of patients with locally advanced disease were included. A local complete response rate of 87.5% was obtained. The major acute toxicity was ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528909090794

    authors: Tveit KM,Karlsen KO,Fosså SD,Flokkmann A,Guldvog I,Haffner J

    更新日期:1989-12-01 00:00:00

  • Coeliac disease does not affect visual acuity: a study of young men in the Swedish national conscripts register.

    abstract::OBJECTIVE. Coeliac disease (CD) is associated with neurological disease, but there are little data on visual acuity in CD. The objective of this study was to examine visual acuity in undiagnosed and diagnosed CD. MATERIAL AND METHODS. Visual acuity was evaluated in Swedish male conscripts: 69 with undiagnosed CD (diag...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365520903194583

    authors: Mollazadegan K,Ludvigsson JF

    更新日期:2009-01-01 00:00:00

  • Low clinical relevance of the nonalcoholic fatty liver disease activity score (NAS) in predicting fibrosis progression.

    abstract:BACKGROUND/AIMS:The nonalcoholic fatty liver disease (NAFLD) activity score (NAS) is a newly proposed system to grade the necroinflammatory activity in liver biopsies of NAFLD patients. This study evaluates the usefulness of the NAS in predicting clinical deterioration and fibrosis progression in NAFLD. METHODS:One hu...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2011.634024

    authors: Ekstedt M,Franzén LE,Mathiesen UL,Kechagias S

    更新日期:2012-01-01 00:00:00

  • S100A9 as a novel diagnostic and prognostic biomarker in human gastric cancer.

    abstract::Objective: The morbidity and mortality of gastric cancer (GC) is high, but there are lack of the biomarkers for early diagnosis and progression of GC. We aimed to identify a novel biomarker for the growth and progression of GC.Methods: The Cancer Genome Atlas (TCGA) database including 352 eligible patients was used to...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2020.1737883

    authors: Zhao Z,Zhang C,Zhao Q

    更新日期:2020-03-01 00:00:00