Necessity of multiple gastric biopsies from different sites for detection of clarithromycin-resistant Helicobacter pylori strains.

Abstract:

BACKGROUND:It has been reported that approximately 10% of patients infected with Helicobacter pylori have both clarithromycin-susceptible and clathromycin-resistant strains. However, there have been no reports indicating whether only one gastric biopsy is sufficient to detect clarithromycin-resistant strains. METHODS:Sixty-five H. pylori-infected patients were selected for this study, and 40 of them were given clarithromycin-based eradication therapy. Four gastric biopsies, 2 from the antrum and 2 from the corpus, were obtained from each of the 65 patients. Susceptibility of H. pylori strains to clarithromycin was examined by detecting mutations of the 23S ribosomal RNA (rRNA) gene of H. pylori. RESULTS:The clarithromycin-resistant strains were detected in 16 of the 65 (25%) patients. Only 5 of the 16 (31%) patients had the resistant strains in both the antrum and corpus. When only 1 or the other biopsy from the antrum was used, the resistant strains were detected in 8 (50%) or 9 (56%) of the 16 patients. CONCLUSIONS:These data indicate that multiple gastric biopsies from both the antrum and the corpus should be used to detect clarithromycin-resistant H. pylori strains.

journal_name

Scand J Gastroenterol

authors

Masuda H,Hiyama T,Yoshihara M,Tanaka S,Shimamoto F,Haruma K,Chayama K

doi

10.1080/00365520310004731

subject

Has Abstract

pub_date

2003-09-01 00:00:00

pages

942-6

issue

9

eissn

0036-5521

issn

1502-7708

journal_volume

38

pub_type

杂志文章
  • Chronic non-A, non-B hepatitis. A long-term follow-up study in 49 patients.

    abstract::Forty-nine patients with biopsy-verified chronic non-A, non-B hepatitis (NANBH) of both percutaneously transmitted and sporadic types were followed up for up to 20 years (mean, 62 months +/- 44 months). Drug addicts were not included. Twenty-four patients had chronic persistent hepatitis (CPH), and 25 had chronic acti...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528708991968

    authors: Wejstål R,Lindberg J,Lundin P,Norkrans G

    更新日期:1987-11-01 00:00:00

  • The postcholecystectomy syndrome: bile ducts as pain trigger zone.

    abstract::Sixty-five non-icteric patients presumed to have the postcholecystectomy syndrome (PCS) were followed up for 4-13 years after their first endoscopic retrograde cholangiopancreatography (ERCP) examination, which gave normal findings. All patients, however, experienced severe pain on injection of only 1-2 ml of contrast...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528809093863

    authors: Lasson A,Fork FT,Trägårdh B,Zederfeldt B

    更新日期:1988-04-01 00:00:00

  • Prevalence and determinants of exocrine pancreatic insufficiency among older adults: results of a population-based study.

    abstract:OBJECTIVE:The prevalence and main determinants of exocrine pancreatic insufficiency were investigated in a large population-based sample of older adults by measuring pancreatic elastase-1 in stool. MATERIAL AND METHODS:The study comprised 914 participants aged 50 to 75 years recruited by their general practitioner dur...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520510023116

    authors: Rothenbacher D,Löw M,Hardt PD,Klör HU,Ziegler H,Brenner H

    更新日期:2005-06-01 00:00:00

  • Jejunal morphology and mucosal enzyme activity following intestinal shunt operation for obesity.

    abstract::Jejunal biopsy in 33 patients before and after intestinal shunt operation for obesity has demonstrated that neither surface nor volume of the villi increase after surgery. Specific disaccharidase activity remained unchanged, and specific alkaline phosphatase activity increased slightly. There was a significant decreas...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Danö P,Nielsen OV,Petri M,Jörgensen B

    更新日期:1976-01-01 00:00:00

  • Disease activity and serum proteins in ulcerative colitis. Immunochemical quantitation.

    abstract::Nine different serum proteins from 50 patients suffering from ulcerative colitis were quantitated by means of Laurell's rocket-electrophoresis. The periods of study extended for up to five years. Twenty-six patients were seen at brief intervals from days up to two months; 18 patients were seen at intervals from two to...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Marner IL,Friborg S,Simonsen E

    更新日期:1975-01-01 00:00:00

  • Subnormal alanine aminotransferase values in blood of patients with Crohn disease.

    abstract:BACKGROUND:It was observed that several patients from the outpatient clinic with Crohn disease (CD) occasionally had subnormal values of alanine aminotransferase (ALAT) in blood. Subnormal ALAT values have previously been reported only in renal failure. METHODS:A retrospective study of clinical chemistry values going ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520410005162

    authors: Vadstrup S

    更新日期:2004-06-01 00:00:00

  • Urinary prostaglandins and renal function in chronic liver diseases.

    abstract::Changes in urinary PGE2 and PGF2 alpha excretion in chronic liver diseases were observed in relation to renal hemodynamics and sodium balance. After equilibration on a 110-170-meq sodium diet, daily urine collections were analyzed for PGE2 and PGF2 alpha by a new extraction and radioimmunoassay method. PGE2 was signif...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528609034626

    authors: Uemura M,Tsujii T,Fukui H,Kita K,Takaya A,Tsukamoto N,Nakayama M,Matsumoto M,Tamura M

    更新日期:1986-01-01 00:00:00

  • Systematic expression profiling of the gastric H+/K+ ATPase in human tissue.

    abstract:OBJECTIVE:The potassium-competitive acid blockers (P-CABs), comprise a new, innovative group of competitive and reversible inhibitors of the gastric H+/K+ ATPase. Our aim was to identify sites of expression of the H+/K+ ATPase that are potential targets of these compounds by examining the expression profile of the gast...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520701405579

    authors: Herrmann M,Selige J,Raffael S,Sachs G,Brambilla A,Klein T

    更新日期:2007-11-01 00:00:00

  • Secondary C-kit mutation is a cause of acquired resistance to imatinib in gastrointestinal stromal tumor.

    abstract::C-kit gene gain of function mutations are important in the pathogenesis of gastrointestinal stromal tumors (GISTs). Imatinib is a selective tyrosine kinase inhibitor of KIT and achieves a partial response or stable disease in most patients with metastatic GIST, but there is increasing evidence of acquired resistance. ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520802647459

    authors: Zheng S,Pan YL,Tao DY,Wang JL,Huang KE

    更新日期:2009-01-01 00:00:00

  • Assessment of blood flow in the small intestine with laser Doppler flowmetry.

    abstract::Blood flow in the small intestine was assessed in 48 patients by laser Doppler flowmetry. Mucosal and serosal flowmeter signals were compared during 'resting' conditions, vascular occlusion, and reactive hyperemia. Serosal flowmeter recordings were compared with the total blood flow of a bowel segment as measured by v...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528609011131

    authors: Ahn H,Lindhagen J,Nilsson GE,Oberg PA,Lundgren O

    更新日期:1986-09-01 00:00:00

  • Gastrointestinal bleeding due to peptic ulcers and erosions - a prospective observational study (BLUE study).

    abstract:OBJECTIVES:Acute upper gastrointestinal bleeding is a well-recognized complication of peptic ulcers and erosions. The aim of this study was to assess the incidence rate and identify risk factors for this complication in southeastern Norway. MATERIALS AND METHODS:Between March 2015 and December 2017, a prospective obse...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2020.1819405

    authors: Romstad KK,Detlie TE,Søberg T,Ricanek P,Jahnsen ME,Lerang F,Jahnsen J

    更新日期:2020-10-01 00:00:00

  • Selective inhibitors of COX-2--are they safe for the stomach?

    abstract::NSAIDs are widely used and beneficial for patients with inflammatory pain. However, NSAIDs cause significant adverse upper gastrointestinal effects, including increased mortality from serious ulcer complications. NSAIDs exert their anti-inflammatory effects by inhibiting the activity of the COX enzyme, which was recen...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1080/003655200750056565

    authors: Giercksky KE,Haglund U,Rask-Madsen J

    更新日期:2000-11-01 00:00:00

  • Propranolol in prevention of rebleeding from oesophageal varices during the course of endoscopic sclerotherapy.

    abstract::Thirty-one patients admitted with the first bleeding episode from oesophageal varices were randomized in a double-blind manner to receive oral propranolol, 160 mg daily, for 6 months (n = 15) or matching placebo (n = 16) for the same period. Endoscopy was performed each month during the 6 months and additionally after...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00365528909093057

    authors: Jensen LS,Krarup N

    更新日期:1989-04-01 00:00:00

  • Fenfluramine and idiopathic pain: a serotonergic study in non-psychiatric patients with functional gastrointestinal disorder.

    abstract:BACKGROUND:We investigated prolactin and cortisol response to fenfluramine in non-psychiatric patients with chronic functional gastrointestinal disorder (FGD). METHODS:Sixty milligrams fenfluramine was given orally to 55 subjects without any DSM-III axis-1 psychopathology and 29 healthy control subjects matched for se...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.1080/00365529850171602

    authors: Tanum L,Bråtveit-Johansen K,Malt UF

    更新日期:1998-07-01 00:00:00

  • Significance of histologic criteria for the management of patients with malignant colorectal polyps and polypectomy.

    abstract:BACKGROUND:The management of invasive cancer in colorectal polyps (malignant polyps) is controversial, particularly with regard to the different sets of histologic criteria for deciding whether malignant colorectal polyps should be treated by polypectomy alone or be followed by surgical resection. We report on the outc...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529709011201

    authors: Netzer P,Binek J,Hammer B,Lange J,Schmassmann A

    更新日期:1997-09-01 00:00:00

  • Hepatitis C and the leptin system: bound leptin levels are elevated in patients with hepatitis C and decrease during antiviral therapy.

    abstract:BACKGROUND:Serum leptin levels are elevated in alcoholic liver cirrhosis and thus might be involved in the anorexia and hypermetabolism often seen in those patients. We hypothesized that the leptin system is modulated in patients with hepatitis C and might be affected by antiviral therapy. The aim of this study was to ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.1080/003655201300051333

    authors: Widjaja A,Wedemeyer H,Tillmann HL,Horn R,Ockenga J,Jaeckel E,von zur Mühlen A,Manns MP,Brabant G

    更新日期:2001-04-01 00:00:00

  • Effect of platelet-derived growth factor-BB on indomethacin-induced gastric lesions in rats.

    abstract::The effect of platelet-derived growth factor-BB (PDGF-BB) was evaluated in rats with indomethacin-induced gastric lesions. Animals were treated with either saline solution or several doses of PDGF-BB given orally. Rats treated with 0.1 nmol/kg PDGF-BB showed a statistically significant reduction of gastric damage. Hig...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529209000138

    authors: Guglietta A,Hervada T,Nardi RV,Lesch CA

    更新日期:1992-08-01 00:00:00

  • Depletion of enteric gonadotropin-releasing hormone is found in a few patients suffering from severe gastrointestinal dysmotility.

    abstract:OBJECTIVE:Many patients, especially women, suffer from severe gastrointestinal pain and dysmotility for several years without being diagnosed. Depletion of gonadotropin-releasing hormone (GnRH) in the enteric nervous system (ENS) has been described in some patients. The aim of this study was to examine the expression o...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2012.706826

    authors: Hammar O,Ohlsson B,Veress B,Alm R,Fredrikson GN,Montgomery A

    更新日期:2012-10-01 00:00:00

  • Effect of omeprazole, a substituted benzimidazole, on 24-h intragastric acidity in patients with peptic ulcer disease.

    abstract::Intragastric pH was measured during physiological conditions over 24-h periods in patients with peptic ulcer disease. After single oral doses of 20, 40, and 80 mg omeprazole we found a dose-dependent reduction in mean intragastric acidity ranging from 38% to 99%. After treatment for 1 week with omeprazole, 40 mg daily...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Naesdal J,Bodemar G,Walan A

    更新日期:1984-10-01 00:00:00

  • Mortality from gastric cancer in patients followed with upper gastrointestinal endoscopy.

    abstract:OBJECTIVE:Although commonly practiced in Japan, the effectiveness of regular screening with upper gastrointestinal (UGI) endoscopy against gastric cancer has not been well evidenced. The aim of the study was to investigate if gastric cancer-related mortality can be reduced by regular endoscopy. MATERIAL AND METHODS:Th...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520701813954

    authors: Ogura M,Hikiba Y,Maeda S,Matsumura M,Okano K,Sassa R,Yoshida H,Kawabe T,Omata M

    更新日期:2008-01-01 00:00:00

  • Type I and III collagens in human colon cancer and diverticulosis.

    abstract:BACKGROUND:Collagens are major proteins in the extracellular matrix, providing tissues with tensile strength. They are also important for cell adhesion and the invasion of malignant tumours. METHODS:Thirty-nine samples of human colon (24 diverticulosis, 6 malignant tumours, 9 controls) were collected during elective s...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655200750023435

    authors: Bode MK,Karttunen TJ,Mäkelä J,Risteli L,Risteli J

    更新日期:2000-07-01 00:00:00

  • Gallbladder volume in patients with common hepatic duct dilatation. An evaluation of Courvoisier's sign using ultrasonography.

    abstract::To evaluate the usefulness of Courvoisier's sign in ultrasonography, gallbladder size in patients with common hepatic duct dilatation was measured using the ellipsoid method during ultrasonographic examination. During a 6-month period 24 patients with malignant obstructions (6 with carcinoma of the ampulla of Vater, 9...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529409090478

    authors: Chen JJ,Changchien CS,Tai DI,Kuo CH

    更新日期:1994-03-01 00:00:00

  • The influence of Helicobacter pylori eradication on the gastric mucosal content of epidermal growth factor, transforming growth factor-alpha, and their common receptor.

    abstract:BACKGROUND:The relationship between the expression of epidermal growth factor (EGF) and transforming growth factor-alpha (TGF-alpha) and that of their receptor (EGF-R) in the Helicobacter pylori-infected gastric mucosa has not been completely elucidated. The aim of this study was to examine the interplay between H. pyl...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365529850170856

    authors: Russo F,Messa C,Amati L,Caradonna L,Leoci C,Di Matteo G,Jirillo E,Di Leo A

    更新日期:1998-03-01 00:00:00

  • Reproducibility of ambulatory gastric pH recordings in the corpus and antrum. Effect of food, time, and electrode position.

    abstract::The reproducibility of simultaneous, long-term, ambulatory gastric pH recordings in the antrum and corpus was investigated in nine healthy subjects who underwent three separate, 27-h gastric double pH-metries. Intraindividual reproducibility for the entire 27-h recording period was good in the corpus (Kendall's concor...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529008997637

    authors: Cilluffo T,Armstrong D,Castiglione F,Emde C,Galeazzi R,Gonvers JJ,Blum AL

    更新日期:1990-10-01 00:00:00

  • Campylobacter-like organisms in chronic gastritis, peptic ulcer, and gastric carcinoma.

    abstract::Biopsy samples were taken from the gastric mucosa of 209 patients endoscoped for dyspepsia symptoms. Campylobacter-like organisms (CLOs) were cultured from 74 of 179 (41.4%) cases and seen in sections from 110 of 209 (52.6%) cases and in smears from 119 of 209 (56.9%) cases; totally, 145 of 209 cases were positive, gi...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528708991897

    authors: Jiang SJ,Liu WZ,Zhang DZ,Shi Y,Xiao SD,Zhang ZH,Lu DY

    更新日期:1987-06-01 00:00:00

  • The usefulness of endoscopic ultrasound-guided fine-needle aspiration for the diagnosis of pancreatic neuroendocrine tumors based on the World Health Organization classification.

    abstract:BACKGROUND:We assessed the controversial topic of using 22-gauge needles in endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) for the diagnosis and evaluation of Ki67 labeling indices (Ki67LI) of pancreatic neuroendocrine tumors (pNET). METHODS:Thirty-eight patients with pNET who underwent EUS-FNA between ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2014.934909

    authors: Unno J,Kanno A,Masamune A,Kasajima A,Fujishima F,Ishida K,Hamada S,Kume K,Kikuta K,Hirota M,Motoi F,Unno M,Shimosegawa T

    更新日期:2014-11-01 00:00:00

  • IL-1 RN 2/2 genotype and simultaneous carriage of genotypes IL-1 RN 2/2 and IL-1beta-511 T/T associated with oesophagitis in Helicobacter pylori-negative patients.

    abstract:BACKGROUND:Interleukin-1 receptor antagonist genotype 2/2 is associated with a prolonged and enhanced inflammatory response. It is suspected of being a risk factor for atrophic gastritis and gastric cancer and for some autoimmune diseases. No specific genetic risk factors for oesophagitis have been identified so far an...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520310006504

    authors: Koivurova OP,Karhukorpi JM,Joensuu ET,Koistinen PO,Valtonen JM,Karttunen TJ,Niemelä SE,Karttunen RA

    更新日期:2003-12-01 00:00:00

  • A prospective study of fecal calprotectin and lactoferrin as predictors of small bowel Crohn's disease in patients undergoing capsule endoscopy.

    abstract:BACKGROUND:Capsule endoscopy (CE) is often used to investigate small bowel Crohn's disease (CD). AIM:The aim of this study is to prospectively assess the value of fecal calprotectin and lactoferrin to predict CE findings. PATIENTS AND METHODS:Sixty-eight consecutive patients that were referred for CE were included. S...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2016.1253769

    authors: Bar-Gil Shitrit A,Koslowsky B,Livovsky DM,Shitrit D,Paz K,Adar T,Adler SN,Goldin E

    更新日期:2017-03-01 00:00:00

  • Effectiveness of steroid therapy for pancreatic cysts complicating autoimmune pancreatitis and management strategy for cyst-related complications.

    abstract::Objectives: Autoimmune pancreatitis (AIP) sometimes becomes complicated with pancreatic cysts, although their detailed characteristics and management strategy have not been fully determined. We aimed to clarify the efficiency of steroid therapy and the risk factors for cyst formation and cyst-related complications. Me...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2019.1623307

    authors: Kuraishi Y,Watanabe T,Muraki T,Ashihara N,Ozawa M,Nakamura A,Kanai K,Hamano H,Kawa S

    更新日期:2019-06-01 00:00:00

  • Surgical resection for local recurrence after radiofrequency ablation for colorectal liver metastasis is more extensive than primary resection.

    abstract:OBJECTIVE:As a minimally invasive modality, radiofrequency ablation (RFA) has been increasingly applied not only for the treatment of hepatocellular carcinoma, but also for that of colorectal liver metastasis (CLM). However, RFA for CLM has been shown to be associated with a high local recurrence rate, and no optimal t...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2014.893013

    authors: Kawaguchi Y,Hasegawa K,Saiura A,Nagata R,Takahashi M,Oba M,Kaneko J,Aoki T,Sakamoto Y,Sugawara Y,Makuuchi M,Kokudo N

    更新日期:2014-05-01 00:00:00