Assessment of blood flow in the small intestine with laser Doppler flowmetry.

Abstract:

:Blood flow in the small intestine was assessed in 48 patients by laser Doppler flowmetry. Mucosal and serosal flowmeter signals were compared during 'resting' conditions, vascular occlusion, and reactive hyperemia. Serosal flowmeter recordings were compared with the total blood flow of a bowel segment as measured by venous collection. The magnitudes of the mucosal (n = 49) and serosal (n = 49) flowmeter signals were comparable throughout the whole range of flowmeter signals (r = 0.97; p less than 0.001). A correlation coefficient of 0.95 (n = 51; p less than 0.001) was obtained between serosal flowmeter signals and total blood flow during 'resting' and reduced blood flows. During vasodilatation after a vascular occlusion, blood flow was underestimated by the flowmeter. A calibration curve could be constructed for approximate interpretation of the flowmeter signals in absolute flow units. The present study underlines the potential of laser Doppler flowmetry in the assessment of blood flow in the human small intestine.

journal_name

Scand J Gastroenterol

authors

Ahn H,Lindhagen J,Nilsson GE,Oberg PA,Lundgren O

doi

10.3109/00365528609011131

subject

Has Abstract

pub_date

1986-09-01 00:00:00

pages

863-70

issue

7

eissn

0036-5521

issn

1502-7708

journal_volume

21

pub_type

杂志文章
  • Efficacy and safety of endoscopic submucosal dissection for gastrointestinal neuroendocrine tumors: a 10-year data analysis of Northern China.

    abstract::Objective: Endoscopy is the main method to treat gastrointestinal neuroendocrine tumors (GI-NETs), but the specific indications are still controversial. We aim to investigate the clinical outcomes of GI-NETs patients who experienced endoscopic submucosal dissection (ESD). Methods: We retrospectively reviewed the clini...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2019.1588367

    authors: Chen X,Li B,Wang S,Yang B,Zhu L,Ma S,Wu J,He Q,Zhao J,Zheng Z,Li S,Wang T,Liang L

    更新日期:2019-03-01 00:00:00

  • A non-invasive fibrosis score predicts treatment outcome in chronic hepatitis C virus infection.

    abstract:OBJECTIVE:The results of a previous study suggest that an index calculated according to the formula (normalized ASAT x PK-INR) x 100/thrombocyte count (x 10(9)/L; GUCI) may reflect liver fibrosis in patients with chronic hepatitis C virus (HCV) infection. The aims of the present study were (i) to validate the associati...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520701514461

    authors: Westin J,Ydreborg M,Islam S,Alsiö A,Dhillon AP,Pawlotsky JM,Zeuzem S,Schalm SW,Ferrari C,Neumann AU,Hellstrand K,Lagging M,DITTO-HCV Study Group.

    更新日期:2008-01-01 00:00:00

  • The storage time of monoiodinated gastrin affects the biological activity and binding to rat fundic plasma membranes similarly, whereas the immunoreactivity is less affected.

    abstract::Monoiodinated gastrin was produced by a gentle Iodo-gen method, followed by gel and ion-exchange chromatography. During storage this tracer has previously been found to retain its immunological activity, whereas its specific binding to rat gastric fundic plasma membranes decreased rapidly. To examine whether the loss ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528708991480

    authors: Kleveland PM,Waldum HL

    更新日期:1987-05-01 00:00:00

  • Parental occupations and risk for Crohn's disease in children.

    abstract:BACKGROUND AND OBJECTIVES:Lacunae exist on the identity of specific environmental risk factors that associate with Crohn's disease (CD). We hypothesized that indirect exposures acquired via the parents' occupation may confer susceptibility. METHODS:A case-control study based on children diagnosed with CD (prior to age...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2017.1339826

    authors: Eslahpazir J,Kumar R,Lalavi A,Amre DK

    更新日期:2017-10-01 00:00:00

  • Hepatic lesions in adult coeliac disease.

    abstract::In the period 1970 to 1987, 171 patients with small-intestinal mucosal atrophy have been hospitalized in our department. Of these, 132 patients fulfilled the diagnostic criteria of coeliac disease on the basis of histologic findings and clinical improvement on a gluten-free diet. Aspartate aminotransferase (ASAT), ala...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529008997589

    authors: Jacobsen MB,Fausa O,Elgjo K,Schrumpf E

    更新日期:1990-07-01 00:00:00

  • Evaluation of the marker technique for measurement of exocrine pancreatic secretion rate.

    abstract::A secretin-cholecystokinin test was performed in 103 patients, representing both normal and reduced exocrine pancreatic function. The duodenum was intubated with a triple-lumen tube. The gastric and duodenal contents were aspirated separately and sampled in 10-min periods. An inert, water-soluble marker (58Co-vitamin ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.3109/00365528509089691

    authors: Rune SJ,Worning H

    更新日期:1985-05-01 00:00:00

  • Role of miR-19a targeting TNF-α in mediating ulcerative colitis.

    abstract:OBJECTIVE:Ulcerative colitis (UC) is a widely studied inflammatory disease associated with differential expression of genes involved in immune function, wound healing, and tissue remodeling. MicroRNAs have been reported to play a role in various cancer types. However, the mechanism of how microRNAs regulate UC remains ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2013.800991

    authors: Chen B,She S,Li D,Liu Z,Yang X,Zeng Z,Liu F

    更新日期:2013-07-01 00:00:00

  • Prevalence and incidence of pernicious anemia. An evaluation for gastric screening.

    abstract::To evaluate the feasibility of gastroscopic screening for gastric malignancy in patients with pernicious anemia, all individuals treated with vitamin B12 in a well-defined population were identified. Individuals treated for an uncertain diagnosis were submitted to supplementary examinations. Of all individuals treated...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Borch K,Liedberg G

    更新日期:1984-03-01 00:00:00

  • Lymphocyte subpopulations, lymphoblast transformation activity, and concanavalin A-induced suppressor activity in patients with ulcerative colitis and Crohn's disease.

    abstract::The following immunologic in vitro tests were applied on peripheral blood mononuclear cells (PBMC) from patients with chronic inflammatory bowel disease (IBD): concanavalin A (Con A)-induced suppressor test, Con A-activated lymphoblast transformation test, and spontaneous lymphoblast transformation test. Concomitant p...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528708991915

    authors: Davidsen B,Kristensen E

    更新日期:1987-09-01 00:00:00

  • Relative role of APC and MUTYH mutations in the pathogenesis of familial adenomatous polyposis.

    abstract:OBJECTIVE:Familial adenomatous polyposis (FAP) is an interesting model for the study of colorectal tumour. Two genes contribute to the FAP phenotype - APC and MUTYH - but their relative role is still undefined. The objective of this study was to evaluate the contribution of the two genes to the pathogenesis of FAP by m...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520903100481

    authors: Pezzi A,Roncucci L,Benatti P,Sassatelli R,Varesco L,Di Gregorio C,Venesio T,Pedroni M,Maffei S,Reggiani Bonetti L,Borsi E,Ferrari M,Martella P,Rossi G,Ponz De Leon M

    更新日期:2009-01-01 00:00:00

  • Is electrostimulation of the pelvic floor an effective treatment for neurogenic faecal incontinence?

    abstract:BACKGROUND:This study was designed to evaluate the results of electrostimulation of the pelvic floor for faecal incontinence. METHODS:Twenty-four patients with neurogenic (n = 20) or idiopathic (n = 4) incontinence were treated on 12 occasions. Twenty were women, and the mean age was 63 years (range, 26-85 years). The...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365529950173762

    authors: Osterberg A,Graf W,Eeg-Olofsson K,Hålldén M,Påhlman L

    更新日期:1999-03-01 00:00:00

  • Transjugular intrahepatic portosystemic shunt with the Strecker stent for control of refractory acute and chronic variceal bleeding.

    abstract:BACKGROUND:We wanted to assess prospectively the safety, efficacy, and applicability of transjugular intrahepatic portosystemic shunt (TIPS) with the Strecker stent, focusing mainly on clinical and hemodynamic medium- and long-term follow-up. METHODS:Fifty-two patients reached an indication to perform a TIPS, in an em...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529609004880

    authors: Canizares RB,Rodriguez-Laiz JM,Martin MC,Belda AE,Alonso FC,Roldan FP,Castro LS,Arregui EC,Ricote GC

    更新日期:1996-03-01 00:00:00

  • Is transcatheter arterial embolization a safer alternative than surgery when endoscopic therapy fails in bleeding duodenal ulcer?

    abstract:OBJECTIVE:Emergency surgery after unsuccessful endoscopic therapy for bleeding duodenal ulcer has been reported to have a high mortality. Transcatheter arterial embolization (TAE) of the gastroduodenal artery is an alternative strategy when endoscopic therapy fails. This study is a retrospective analysis comparing thes...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365520903486109

    authors: Venclauskas L,Bratlie SO,Zachrisson K,Maleckas A,Pundzius J,Jönson C

    更新日期:2010-03-01 00:00:00

  • Incidence, diagnostic, treatment and outcome of patients diagnosed with cancer of the pancreas during 1986-2009: a population-based study.

    abstract:OBJECTIVE:Limited data exist on the changes in the epidemiology of pancreatic cancer and outcomes over the last decades in population-based cohorts. We aimed to compare the incidence of pancreatic cancer, diagnostic, treatment and survival among patients diagnosed over the period 1986-2009. MATERIALS AND METHODS:A ret...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2017.1390598

    authors: Jonsdottir SB,Juliusson G,Kristinsson JÖ,Hreinsson JP,Jonasson JG,Björnsson ES

    更新日期:2018-01-01 00:00:00

  • A prospective reappraisal of emergency endoscopy in patients with portal hypertension.

    abstract::In a prospective study of emergency endoscopy in patients with portal hypertension and oesophageal varices referred to King's College Hospital with acute upper gastrointestinal bleeding, initial endoscopic examination on 90 separate consecutive hospital admissions carried out within 24 h of clinical haemorrhage showed...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Mitchell KJ,MacDougall BR,Silk DB,Williams R

    更新日期:1982-11-01 00:00:00

  • Helicobacter pylori and bleeding duodenal ulcer: prevalence of the infection and role of non-steroidal anti-inflammatory drugs.

    abstract:BACKGROUND:Several authors have reported low prevalence of Helicobacter pylori infection in patients with upper gastrointestinal bleeding (UGIB). Our aim was to study the prevalence of H. pylori in bleeding duodenal ulcer (DU), with both invasive and non-invasive methods, and to assess the role of non-steroidal anti-in...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655201300191978

    authors: Gisbert JP,Gonzalez L,de Pedro A,Valbuena M,Prieto B,Llorca I,Briz R,Khorrami S,Garcia-Gravalos R,Pajares JM

    更新日期:2001-07-01 00:00:00

  • Partially covered versus uncovered self-expandable nitinol stents with anti-migration properties for the palliation of malignant distal biliary obstruction: A randomized controlled trial.

    abstract:OBJECTIVE:Covered self-expandable metal stents (SEMSs) are increasingly used as alternatives to uncovered SEMSs for the palliation of inoperable malignant distal biliary obstruction to counteract tumor ingrowth. We aimed to compare the outcomes of partially covered and uncovered SEMSs with identical mesh structures and...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.3109/00365521.2015.1057219

    authors: Yang MJ,Kim JH,Yoo BM,Hwang JC,Yoo JH,Lee KS,Kang JK,Kim SS,Lim SG,Shin SJ,Cheong JY,Lee KM,Lee KJ,Cho SW

    更新日期:2015-01-01 00:00:00

  • Reversibility of the cell kinetic changes induced by omeprazole in the rat oxyntic mucosa. An autoradiographic study using tritiated thymidine.

    abstract::Both oxyntic mucosal progenitor cells and enterochromaffin-like (ECL) cells are under the trophic control of gastrin. We studied the effect of discontinuing omeprazole-induced hypergastrinemia on cell proliferation and ECL cell function in the rat oxyntic mucosa. All rats had hypergastrinemia after 16 days' omeprazole...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529209165437

    authors: Tielemans Y,Chen D,Sundler F,Håkanson R,Willems G

    更新日期:1992-01-01 00:00:00

  • Effect of bulbar perfusion with acid, hypertonic solutions, and acetylcholine on gastric acid secretion in dogs.

    abstract::Dogs were provided with innervated pouches of the fundic stomach and the duodenal bulb. One dog also had an isolated pouch of the distal duodenum. Acid secretion was stimulated by intravenous infusion of a low dose of pentagastrin (ICI 50 123). Bulbar pouches were perfused with solutions of 0.9% Na C1, 0.1 N HC1, 40% ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Nilsson G

    更新日期:1975-01-01 00:00:00

  • Chronic non-specific diarrhea of infancy successfully treated with trimethoprim-sulfamethoxazole.

    abstract::Fifteen children who fulfilled the criteria of chronic non-specific diarrhea of infancy were evaluated for intestinal bacterial overgrowth. In 10 of 11 successfully investigated children we found bacterial overgrowth of the small intestine by upper respiratory tract microflora. In 9 of 10 children (group I) treated wi...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.3109/00365528909093094

    authors: Dahlström KA,Danielsson L,Kalin M,Klingspor L

    更新日期:1989-06-01 00:00:00

  • Diagnostic performance of current guidelines and postoperative outcome following surgical treatment of cystic pancreatic lesions - a 10-year single center experience.

    abstract:OBJECTIVE:Pancreatic cystic lesions (PCLs) are diagnostically challenging and there are currently several different guidelines. The aim of this study was to compare diagnostic performance of the most widely utilized International Association of Pancreatology (IAP) guidelines and the recent evidence-based European guide...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2020.1841283

    authors: Kovacevic B,Hansen MC,Kristensen TS,Karstensen JG,Klausen P,Storkholm J,Hansen CP,Vilmann P

    更新日期:2020-12-01 00:00:00

  • Predictors of quality-of-life after ileal pouch-anal anastomosis in patients with ulcerative colitis.

    abstract:OBJECTIVES:Predictors of the postoperative quality of life (QoL) following ileal pouch anal anastomosis (IPAA) have not been thoroughly investigated. This study was planned to assess the postoperative QoL following IPAA and to identify its predictors using the 15D instrument. MATERIALS AND METHODS:A retrospective coho...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2017.1337218

    authors: Abolfotouh S,Rautio T,Klintrup K,Helavirta I,Mäkelä J

    更新日期:2017-10-01 00:00:00

  • Urinary nitric oxide during one year of gluten-free diet with or without oats in children with coeliac disease.

    abstract:OBJECTIVE:Although in both adults and children with coeliac disease (CD) it is now recommended that oats be added to their gluten-free diet, there is still some controversy concerning the possible harmful effects of oats in some individuals. In this study concentrations of nitric oxide metabolites were repeatedly measu...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1080/00365520600684563

    authors: Hollén E,Forslund T,Högberg L,Laurin P,Stenhammar L,Fälth-Magnusson K,Magnusson KE,Sundqvist T

    更新日期:2006-11-01 00:00:00

  • Predictors of septic shock in initially stable patients with pyogenic liver abscess.

    abstract:OBJECTIVES:The incidence of pyogenic liver abscess (PLA), a life-threatening condition, is increasing worldwide. This study was designed to evaluate clinical features and outcomes in initially stable patients with PLA and to determine the predictors of septic shock. METHODS:The medical records of all adult patients wh...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2017.1288757

    authors: Cho H,Lee ES,Lee YS,Kim YJ,Sohn CH,Ahn S,Seo DW,Lee JH,Kim WY,Lim KS

    更新日期:2017-05-01 00:00:00

  • Biodegradable biliary stents preferable to plastic stent therapy in post-cholecystectomy bile leak and avoid second endoscopy.

    abstract:BACKGROUND:The treatment of post-cholecystectomy bile leak is endoscopic retrograde cholangiography (ERC) with plastic stent (PS) insertion combined with external drainage. Self-expanding biodegradable biliary stents (BDBS) have only recently become available. AIM:The aim was to compare success rate, adverse events an...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2018.1518480

    authors: Siiki A,Vaalavuo Y,Antila A,Ukkonen M,Rinta-Kiikka I,Sand J,Laukkarinen J

    更新日期:2018-01-01 00:00:00

  • Fatty acid patterns of serum triglycerides and subcutaneous adipose tissues after ileal bypass in obesity.

    abstract::A group of 9 obese subjects with a mean body weight of 140 kg was treated for their obesity with a jejuno-ileal intestinal shunt. During the first post-operative year their mean body weight decreased to 100 kg. Fatty acid patterns of triglycerides inserum and subcutaneous adipose tissue were studied at intervals durin...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Kallner A,Hallberg D,Backman L

    更新日期:1975-01-01 00:00:00

  • Relation between histologic subtypes and location of gastric cancer and Helicobacter pylori.

    abstract:BACKGROUND:Epidemiologic studies have consistently shown an association between Helicobacter pylori infection and gastric cancer, and it is now widely accepted that this organism plays a role in the pathogenesis of this tumor. Nevertheless, there are discrepant results on its relationship with the histologic type and l...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529709007676

    authors: Martín-de-Argila C,Boixeda D,Redondo C,Alvarez I,Gisbert JP,García Plaza A,Cantón R

    更新日期:1997-04-01 00:00:00

  • Collagen metabolites in the peripheral and splanchnic circulation of patients with Crohn disease.

    abstract:BACKGROUND:Fragments of collagen arising during synthesis and breakdown have been suggested as markers of fibrous tissue remodelling in Crohn disease. We compared serum concentrations of the C-terminal propeptide of collagen I (PICP), the N-terminal propeptide of collagen III (PIIINP) and the C-terminal telopeptide of ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520152584833

    authors: Kjeldsen J,Rasmussen M,Schaffalitzky de Muckadell OB,Kronborg O,Junker P

    更新日期:2001-11-01 00:00:00

  • Passage of molecules through the wall of the gastrointestinal tract. Increased passive permeability in rat ileum after exposure to lysolecithin.

    abstract::The interaction between lysolecithin and mucosal cells in the distal ileum has been studied. Using a rat experimental model, we determined the intestinal permeability to fluorescent dextran 3000 after exposure to different amounts of lysolecithin. At pH 7.3, lysolecithin, 10 mg/ml, significantly enhanced the transmura...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528109181820

    authors: Bolin T,Sjödahl R,Sundqvist T,Tagesson C

    更新日期:1981-01-01 00:00:00

  • A novel one-hour 13C-sorbitol breath test versus the H2-sorbitol breath test for assessment of coeliac disease.

    abstract:OBJECTIVE:The H(2)-sorbitol breath test (H(2)-SBT) has previously been suggested as a screening tool for coeliac disease. We developed an alternative (13)C-sorbitol breath test ((13)C-SBT). The aim of the study was to compare the diagnostic properties of the H(2)-SBT and the (13)C-SBT in a clinical setting. MATERIAL A...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520902846233

    authors: Tveito K,Hetta AK,Askedal M,Brunborg C,Sandvik L,Løberg EM,Skar V

    更新日期:2009-01-01 00:00:00