Efficacy and safety profile of calcineurin inhibitor salvage therapy in autoimmune hepatitis.

abstract：BACKGROUND:Gastrointestinal angiodysplasias (GIAD) bleeding and obscure gastrointestinal bleeding (OGIB) are increasing health problems. Somatostatin analogues have been proposed as rescue therapy, but data for lanreotide are scarce. OBJECTIVE:To determine the efficacy, safety and resource saving of long-acting lanreo...

journal_title：Scandinavian journal of gastroenterology

authors： Frago S,Alcedo J,Martín Pena-Galo E,Lázaro M,Ollero L,de la Llama N

更新日期：2018-12-01 00:00:00

abstract：:Mediastinal collection secondary to necrotic acute pancreatitis, is an extremely rare event caused by the posterior rupture of the pancreatic duct into the retroperitoneal space with the penetration of the pancreatic fluid through the diaphragmatic orifices. Infection of the necrotic collection may occur with a conseq...

journal_title：Scandinavian journal of gastroenterology

authors： Pizzicannella M,Pandolfi M,Andrisani G,Signoretti M,Martino M,Rea R,Di Matteo FM

更新日期：2019-02-01 00:00:00

abstract：:Eighty-seven patients with endoscopically healed duodenal ulcers received continuous maintenance treatment with a standard dose of 150 mg ranitidine at night for 6-12 months. The cumulative annual rate of symptomatic reulceration was 24%, whereas a further 25% of asymptomatic relapses were detected with routine endosc...

journal_title：Scandinavian journal of gastroenterology

authors： Boyd EJ,Wilson JA,Wormsley KG

更新日期：1983-03-01 00:00:00

abstract：BACKGROUND:Our object was to study the role of non-steroidal anti-inflammatory drugs (NSAIDs) as a risk factor in upper gastrointestinal bleeding. METHODS:Forty-eight patients with acute bleeding due to esophagitis, gastric or duodenal ulcer, or erosions and 156 age- and sex-matched control patients from the same emer...

journal_title：Scandinavian journal of gastroenterology

authors： Matikainen M,Kangas E

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:International guidelines recommend cholecystectomy within 2-4 weeks after mild to moderate acute biliary pancreatitis (ABP) to prevent recurrence. We aimed to investigate the compliance to guidelines concerning early cholecystectomy and the associated costs. METHODS:Admissions for ABP 2011-2013 were retrosp...

journal_title：Scandinavian journal of gastroenterology

authors： Ragnarsson T,Andersson R,Ansari D,Persson U,Andersson B

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:Malabsorption of low-digestible carbohydrates is physiological, but poorly tolerated in some patients. We investigated symptom anticipation and microbial fermentation as possible mechanisms of carbohydrate intolerance in patients with self-reported food hypersensitivity. MATERIAL AND METHODS:In a randomized,...

journal_title：Scandinavian journal of gastroenterology

authors： Valeur J,Morken MH,Norin E,Midtvedt T,Berstad A

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:Understanding the natural history and outcomes of gastroesophageal reflux disease (GERD) in children could help to identify patients at risk of having GERD complications during adulthood. This review aimed to assess evidence of whether GERD in children or adolescents persists into adulthood. MATERIAL AND MET...

journal_title：Scandinavian journal of gastroenterology

authors： Winter HS,Illueca M,Henderson C,Vaezi M

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:To study T-helper (Th)1-Th2-Th3 gene activation profile in the small intestine and peripheral blood of children with celiac disease (CD) with special interest in the response to the gluten-free diet (GFD) treatment in order to elucidate an immune dysregulation not triggered by gluten. MATERIAL AND METHODS:Sm...

journal_title：Scandinavian journal of gastroenterology

authors： Lahdenperä A,Ludvigsson J,Fälth-Magnusson K,Högberg L,Vaarala O

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:Interstitial cells of Cajal (ICC) have been endowed with considerable intrinsic plasticity. Blockade of the c-kit signaling pathway results in the shift of ICC towards a smooth muscle-like phenotype. Little is known about stem cell factor (SCF), the ligand of c-kit, and the role it plays in the process of res...

journal_title：Scandinavian journal of gastroenterology

authors： Tong W,Jia H,Zhang L,Li C,Ridolfi TJ,Liu B

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Since the effect of exogenous glutathione (GSH) on overall hepatic GSH homeostasis is not known, the present study investigated the changes in the hepatic, biliary, and plasmatic GSH levels during GSH administration in intact rats. METHODS:An exteriorized biliary-duodenal fistula was established, and GSH (1...

journal_title：Scandinavian journal of gastroenterology

authors： Vendemiale G,Palmieri V,Palasciano G,Altomare E

更新日期：1994-11-01 00:00:00

abstract：:Acute pancreatitis was induced in pigs by manual retrograde injection of Na-taurocholate into the pancreatic duct. Chromogenic peptide substrate assays showed increased trypsin (TRY) and plasma kallikrein activities (KK), parallel with a reduction of prekallikrein (PKK) levels and functional plasma kallikrein inhibiti...

journal_title：Scandinavian journal of gastroenterology

authors： Ruud TE,Aasen AO,Pillgram-Larsen J,Stadaas JO

更新日期：1986-10-01 00:00:00

abstract：OBJECTIVE:Benign recurrent intrahepatic cholestasis (BRIC) is a rare autosomal recessive inherited disorder characterized by intermittent episodes of cholestatic jaundice. For the patients, the disease is a physical and psychological challenge. There is no curable treatment, but symptomatic relief is described followin...

journal_title：Scandinavian journal of gastroenterology

authors： Folvik G,Hilde O,Helge GO

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Previous studies suggest that E2 prostaglandins and the microflora may participate in the regulation of endocrine cells and of gastrointestinal cell kinetics. Our aim is to examine the actions of endogenous prostaglandins and of the microflora on gastrointestinal cell proliferation and tissue levels of neuro...

journal_title：Scandinavian journal of gastroenterology

authors： Uribe A,Alam M,Midtvedt T,Smedfors B,Theodorsson E

更新日期：1997-07-01 00:00:00

abstract：:The results of ambulatory 24-h esophageal pH monitoring in 67 patients with gastroesophageal reflux symptoms (endoscopic esophagitis, n = 44; normal endoscopy, n = 23) were compared with those of 27 normal subjects without reflux symptoms. Patients with reflux symptoms had significantly increased gastroesophageal refl...

journal_title：Scandinavian journal of gastroenterology

authors： Masclee AA,de Best AC,de Graaf R,Cluysenaer OJ,Jansen JB

更新日期：1990-03-01 00:00:00

abstract：:A group of 9 obese subjects with a mean body weight of 140 kg was treated for their obesity with a jejuno-ileal intestinal shunt. During the first post-operative year their mean body weight decreased to 100 kg. Fatty acid patterns of triglycerides inserum and subcutaneous adipose tissue were studied at intervals durin...

journal_title：Scandinavian journal of gastroenterology

authors： Kallner A,Hallberg D,Backman L

更新日期：1975-01-01 00:00:00

abstract：:Ischemia of the gastric mucosa, for example during hemorrhagic shock, appears to be an important pathogenetic factor in acute bleeding from the upper gastrointestinal tract. In the present experiment the effects on the canine gastric mucosa of hemorrhagic shock (ischemia) and intragastric aspirin in acid and neutral s...

journal_title：Scandinavian journal of gastroenterology

authors： Casalnuovo CA,Kraglund K,Kristensen IB,Amdrup E

更新日期：1984-06-01 00:00:00

abstract：OBJECTIVE:Gastric contents empty from the stomach despite frequent changes in body position. The mechanism that maintains gastric emptying independent of position is poorly understood. The aim of this study was to determine the effects of body position on gastric emptying and motor function. MATERIAL AND METHODS:Twelv...

journal_title：Scandinavian journal of gastroenterology

authors： Steingoetter A,Fox M,Treier R,Weishaupt D,Marincek B,Boesiger P,Fried M,Schwizer W

更新日期：2006-10-01 00:00:00

abstract：:Triglyceride and sterol synthesis was investigated in vitro in the gallbladder mucosa from control subjects and patients with acalculous cholesterolosis. The incorporation rate of 14C-acetate was 1.6 +/- 0.2 nmol/g/h into cholesterol (sum of squalene, methyl sterols, and cholesterol) and 5.7 +/- 0.8 nmol/g/h into trig...

journal_title：Scandinavian journal of gastroenterology

authors： Tilvis RS,Aro J,Strandberg TE,Lempinen M,Miettinen TA

更新日期：1982-04-01 00:00:00

abstract：:A series of 76 patients who have undergone surgical treatment for Crohn's disease is presented. In 14 of the patients surgery was performed for recurrence after previous resection. In total, 91 intestinal resections and one bypass--operation were carried out. Postoperative mortality comprised 4 patients (5.3%), and th...

journal_title：Scandinavian journal of gastroenterology

authors： Nygaard K,Fausa O

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVE:To study serum infliximab (s-IFX) levels in pediatric patients with inflammatory bowel disease (IBD). SUBJECTS AND METHODS:s-IFX trough levels were measured in a total of 133 blood samples of 37 pediatric IBD patients (Crohn's disease, 23): 48 during the induction phase (weeks 2 and 6) and 85 during maintena...

journal_title：Scandinavian journal of gastroenterology

authors： Hämäläinen A,Sipponen T,Kolho KL

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:Radioresistance is considered the main reason for therapeutic failure in radiotherapy of esophageal carcinoma. However, the underlying mechanisms of radioresistance remain elusive. The purpose of this study was to investigate the relationship between p27(kip1) expression and the change of radiosensitivity of ...

journal_title：Scandinavian journal of gastroenterology

authors： Tong Q,Zhang W,Jin S,Li S,Chen Z

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:Treatment with 5-aminosalicylic acid (5-ASA) derivatives is one of the main principles in the therapy of uncomplicated mild to moderate inflammatory bowel diseases (IBD). The beneficial effect of 5-ASA in the treatment of IBD is attributed to its anti-inflammatory and anti-oxidant properties within the inflam...

journal_title：Scandinavian journal of gastroenterology

authors： Baumgart DC,Vierziger K,Sturm A,Wiedenmann B,Dignass AU

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:Despite the apparent lack of clinical interest in the inlet patches of heterotopic gastric mucosa (HGM) in the upper esophagus, the literature contains reports of complications associated with HGM. The aim of this study was to determine the prevalence and clinical importance of HGM in patients referred for up...

journal_title：Scandinavian journal of gastroenterology

authors： Baudet JS,Alarcón-Fernández O,Sánchez Del Río A,Aguirre-Jaime A,León-Gómez N

更新日期：2006-12-01 00:00:00

abstract：:Prostaglandins of the E type stimulate bicarbonate secretion by the duodenal mucosa and inhibit gastric acid secretion, effects that have been related to their anti-ulcer activity. Leukotrienes constitute a more recently discovered branch of the arachidonic acid cascade, and C4 and D4 have been suggested to be ulcerog...

journal_title：Scandinavian journal of gastroenterology

authors： Knutson L,Nimbratt C,Flemström G

更新日期：1988-12-01 00:00:00

abstract：:In 12 healthy volunteers, a rectosigmoid motility index (RSMI) was measured when either placebo, 0.5 mg atropine, or 5 mg pirenzepine was given intravenously as a single dose, double-blind, in random order after a control period of 30 min. Compared with the control period, atropine gave a significant decrease of the R...

journal_title：Scandinavian journal of gastroenterology

authors： Jaup BH,Abrahamsson H,Stockbruegger RW,Rosengren K,Dotevall G

更新日期：1985-11-01 00:00:00

abstract：OBJECTIVE:Intercellular adhesion molecule-1 (ICAM-1) is important in ulcerative colitis (UC) by mediating the arrest and further migration of neutrophils. In vitro studies have shown that colonocytes from chronically inflamed colon and cultured colon cancer cells are capable of expressing ICAM-1. The aim of this study ...

journal_title：Scandinavian journal of gastroenterology

authors： Vainer B,Horn T,Nielsen OH

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Colonic epithelial cells are exposed to a range of potentially harmful luminal factors. including phenols, but it is unresolved whether these compounds impair the integrity of the epithelium. The aim of this study was to describe the effect of phenol exposure on human colonic epithelial cells in vitro and th...

journal_title：Scandinavian journal of gastroenterology

authors： Pedersen G,Brynskov J,Saermark T

更新日期：2002-01-01 00:00:00

abstract：:The effect of glucagon-like peptide-1 (GLP-1) amide on gastric somatostatin and gastrin secretion was investigated in the isolated, vascularly perfused rat stomach preparation. GLP-1 (7-36) amide, 10(-12) to 10(-7)M, dose-dependently increased gastric somatostatin release, achieving maximal stimulation (314 +/- 15% ab...

journal_title：Scandinavian journal of gastroenterology

authors： Eissele R,Koop H,Arnold R

更新日期：1990-05-01 00:00:00

abstract：:The fermentability of cellulose and dietary fibre in common clinical use (Inolaxol, Fiberform, Vi-Siblin, Lunelax, pectin) was measured as the in vitro production of short-chain fatty acids, lactate, and ammonia in 16.6% faecal homogenates from 18 healthy volunteers. The results were compared with the contents of solu...

journal_title：Scandinavian journal of gastroenterology

authors： Mortensen PB,Nordgaard-Andersen I

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:In theory, the optimal method for diagnosing acute hepatitis C is nucleotide amplification. This is because of the significant delay in the emergence of hepatitis C virus (HCV) antibodies. We studied whether the use of HCV polymerase chain reaction (PCR) screening for acute HCV infection in a clinical settin...

journal_title：Scandinavian journal of gastroenterology

authors： Møller JM,Krarup HB

更新日期：2003-05-01 00:00:00