Endogenous prostaglandins and microflora modulate DNA synthesis and neuroendocrine peptides in the rat gastrointestinal tract.

abstract：:Thirty-one patients admitted with the first bleeding episode from oesophageal varices were randomized in a double-blind manner to receive oral propranolol, 160 mg daily, for 6 months (n = 15) or matching placebo (n = 16) for the same period. Endoscopy was performed each month during the 6 months and additionally after...

journal_title：Scandinavian journal of gastroenterology

authors： Jensen LS,Krarup N

更新日期：1989-04-01 00:00:00

abstract：:Both oxyntic mucosal progenitor cells and enterochromaffin-like (ECL) cells are under the trophic control of gastrin. We studied the effect of discontinuing omeprazole-induced hypergastrinemia on cell proliferation and ECL cell function in the rat oxyntic mucosa. All rats had hypergastrinemia after 16 days' omeprazole...

journal_title：Scandinavian journal of gastroenterology

authors： Tielemans Y,Chen D,Sundler F,Håkanson R,Willems G

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:It was observed that several patients from the outpatient clinic with Crohn disease (CD) occasionally had subnormal values of alanine aminotransferase (ALAT) in blood. Subnormal ALAT values have previously been reported only in renal failure. METHODS:A retrospective study of clinical chemistry values going ...

journal_title：Scandinavian journal of gastroenterology

authors： Vadstrup S

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:The colonic degradation of carbohydrates (fermentation) to short-chain fatty acids (SCFAs) appears to have major impacts on colonocyte function, sodium and water absorption, and large-bowel energy salvation, but how to quantify the in vivo fermentation in man is still debatable. METHODS:Indicators of coloni...

journal_title：Scandinavian journal of gastroenterology

authors： Nordgaard I,Hansen BS,Mortensen PB

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:The interrelationship between histamine and gastrin in the physiological regulation of gastric acid secretion is still a matter of dispute. CCK-2 receptors are located on enterochromaffin-like (ECL) cells in corpus mucosa and gastrin stimulates acid production by releasing histamine from the ECL cells, which...

journal_title：Scandinavian journal of gastroenterology

authors： Bakke I,Qvigstad G,Sandvik AK,Waldum HL

更新日期：2001-11-01 00:00:00

abstract：INTRODUCTION:With immunosuppressive therapy of inflammatory bowel diseases (IBDs) becoming more aggressive, the risk of serious infections is increasing. Guidelines are currently being modified in respect to advisable immunizations. The aim of this study was to evaluate the immunization habits of IBD patients in daily ...

journal_title：Scandinavian journal of gastroenterology

authors： Wilckens V,Kannengiesser K,Hoxhold K,Frenkel C,Kucharzik T,Maaser C

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Spider angioma is a common sign in patients with liver cirrhosis, but the pathogenesis is still unclear. Alcohol and hyperestrogenemia are both possible etiologies. This study was designed to investigate the relationship of spider angiomas in patients with liver cirrhosis to alcohol, liver function test resu...

journal_title：Scandinavian journal of gastroenterology

authors： Li CP,Lee FY,Hwang SJ,Chang FY,Lin HC,Lu RH,Hou MC,Chu CJ,Chan CC,Luo JC,Lee SD

更新日期：1999-05-01 00:00:00

abstract：:Continuous intravenous infusion of small doses of vasopressin (0.05 microgram/kg/h) in anaesthetized dogs was effective in reducing gastric mucosal flow, whereas moderate doses (0.2 micrograms/kg/h) induced a substantial flow reduction. Larger doses of vasopressin (2-4 micrograms/kg/h) precipitated massive gastric flo...

journal_title：Scandinavian journal of gastroenterology

authors： Semb BK,Steen S,Solhaug JH

更新日期：1982-10-01 00:00:00

abstract：OBJECTIVE:Few data are available on the relevance of adalimumab (ADA) trough serum levels and anti-ADA antibodies (AAA) during long-term follow-up of patients with Crohn's Disease (CD), and their association with disease outcome. In this study, our aim was to assess ADA trough serum levels and the presence of AAA accor...

journal_title：Scandinavian journal of gastroenterology

authors： Bodini G,Giannini EG,Savarino V,Del Nero L,Pellegatta G,De Maria C,Baldissarro I,Savarino E

更新日期：2016-09-01 00:00:00

abstract：:Fifty-eight outpatients with a clinical and radiological diagnosis of duodenal ulcer completed a double-blind randomized trial of the effect of cimetidine on ulcer symptoms. Patients normally treated in general practice were included in the trial. The patients in the treatment group received cimetidine 1 g daily and t...

journal_title：Scandinavian journal of gastroenterology

authors： Gudmand-Höyer E,Frost F,Jensen KB,Krag E,Rask-Madsen J,Rahbek I,Rune S,Wulff HR

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND AND AIM:If patients with surgically resectable colorectal cancershave synchronous colorectal neoplasms that are difficult to remove by endoscopic mucosal resection, preemptive endoscopic submucosal dissection (ESD) can avoid excessive colorectal resection. The aim of this study was to evaluate the efficacy o...

journal_title：Scandinavian journal of gastroenterology

authors： Yabuuchi Y,Imai K,Hotta K,Ito S,Kishida Y,Manabe S,Yamaoka Y,Hino H,Kagawa H,Shiomi A,Ono H

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:Pancreatic cancer is the second most frequent gastrointestinal cancer in the Western world. Few reports on concomitant trends in pancreatic cancer incidence, diagnosis, mortality and survival exist at the national level. This study provides a baseline overview of the temporal patterns in these four indicators...

journal_title：Scandinavian journal of gastroenterology

authors： Søreide K,Aagnes B,Møller B,Westgaard A,Bray F

更新日期：2010-01-01 00:00:00

abstract：:It has been suggested that gastrin may be a causative factor in the proliferation of gastric fundic mucosal endocrine cells, as seen in the Zollinger-Ellison syndrome and in atrophic gastritis with hypergastrinemia of antral origin. In the present study, morphometrically determined densities of endocrine cells in fund...

journal_title：Scandinavian journal of gastroenterology

authors： Borch K,Renvall H,Liedberg G,Andersen BN

更新日期：1986-04-01 00:00:00

abstract：:Under endoscopic control, biopsy specimens were taken from the oxyntic gland area of the stomach before and after administration of pentagastrin, synthetic secretin, and 13-norleucine motilin (13-nle-motilin), respectively. In 29 volunteers, the basal rate of 14C-leucine incorporation into mucosal protein averaged 41....

journal_title：Scandinavian journal of gastroenterology

authors： Mitznegg P,Domschke W,Domschke S,Belohlavek D,Sprügel W,Strunz U,Wünsch E,Jaeger E,Demling L

更新日期：1976-01-01 00:00:00

abstract：:A case of a Borrmann type 2 advanced gastric cancer with endocrine differentiation is described. Histologically, the cancer was either composed of cells arranged in a tubular pattern or formed solid nests of various sizes. The tubular pattern was composed of a moderately differentiated tubular adenocarcinoma. The hist...

journal_title：Scandinavian journal of gastroenterology

authors： Sugihara A,Nakasho K,Yamada N,Nakagomi N,Tsujimura T,Terada N,Tsuji M

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND/METHODS:The protective effects of trolox C (water-soluble vitamin E), vitamin C, and catalase on bromobenzene (BB)-induced toxicity to isolated rat hepatocytes were evaluated. The glutathione (GSH) content of the hepatocytes exposed to BB was measured. RESULTS:BB caused acute damage to the cells during 2 h ...

journal_title：Scandinavian journal of gastroenterology

authors： Wu J,Karlsson K,Danielsson A

更新日期：1996-08-01 00:00:00

abstract：:Pseudomyxoma peritonei syndrome (PMP) is a rare but fascinating entity in surgical oncology. It consists of the accumulation of mucus in the peritoneal cavity, sometimes in huge amounts, in most of the cases after rupture of an appendiceal tumor. The diagnosis and management of PMP has changed significantly in the pas...

journal_title：Scandinavian journal of gastroenterology

authors： Sebbag G,Sugarbaker PH,Walfisch S,Levy I

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Little is known about the role of intestinal microflora in the development of indomethacin-induced enteropathy. The aim of this study was to evaluate the effects of lactosucrose, an indigestible oligosaccharide, on intestinal microflora and on indomethacin-induced enteropathy in rats. METHODS:Male Wistar ra...

journal_title：Scandinavian journal of gastroenterology

authors： Honda K,Matsumoto T,Kuroki F,Iida M,Oka M,Sawatani I

更新日期：1999-03-01 00:00:00

abstract：:Autonomic nerve function was evaluated in 40 patients with total ulcerative colitis and in 25 patients with irritable bowel syndrome by three established non-invasive tests based on the heart reactions to deep breathing (E/I ratio) and tilt (acceleration and brake index). None of the patients were diabetic. Most of th...

journal_title：Scandinavian journal of gastroenterology

authors： Lindgren S,Stewenius J,Sjölund K,Lilja B,Sundkvist G

更新日期：1993-07-01 00:00:00

abstract：OBJECTIVE:It is unclear why pancreatitis progresses either to mild edematous disease or to severe necrotic disease. The aim of the study was to shed some light on this topic by investigating differences during the early stages of necrotic and edematous pancreatitis. MATERIAL AND METHODS:Piglets were randomized into tw...

journal_title：Scandinavian journal of gastroenterology

authors： Meriläinen S,Mäkelä J,Anttila V,Koivukangas V,Kaakinen H,Niemelä E,Ohtonen P,Risteli J,Karttunen T,Soini Y,Juvonen T

更新日期：2008-01-01 00:00:00

abstract：:Studies are presented dealing with the effects on exocrine and endocrine rat pancreas of repeated subcutaneous injections for 10 days of equivalent doses (Ivy dog units) of commercial (10% pure) cholecystokinin-pancreozymin (CCK-PZ) and of the synthetic C-terminal octapeptide of CCK-PZ. Both rats treated with the comm...

journal_title：Scandinavian journal of gastroenterology

authors： Arnesjö II,Lundquist I

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Allergic diseases and seronegative spondyloarthropathies are frequently observed in ulcerative colitis (UC). In this report we have investigated possible relationships between IgE-mediated allergic disease (AD), allergic contact dermatitis (ACD) and seronegative spondyloarthropathy (SpA) in UC patients at di...

journal_title：Scandinavian journal of gastroenterology

authors： D'Arienzo A,Manguso F,Scarpa R,Astarita C,D'Armiento FP,Bennato R,Gargano D,Sanges M,Mazzacca G

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori plays a key role in production of reactive oxygen metabolites (ROMs). However, the importance of virulent CagA-positive H. pylori strains remains to be determined. The aim of this study was to assess ROMs production in gastric biopsies of patients infected by H. pylori. Results were corre...

journal_title：Scandinavian journal of gastroenterology

authors： Danese S,Cremonini F,Armuzzi A,Candelli M,Papa A,Ojetti V,Pastorelli A,Di Caro S,Zannoni G,De Sole P,Gasbarrini G,Gasbarrini A

更新日期：2001-03-01 00:00:00

abstract：:The effects and the mechanism of natural honey on absolute ethanol-induced gastric lesions were studied in rats. Drugs and/or honey were administered subcutaneously or orally to 48-h fasted animals at different time intervals before oral administration of ethanol (0.5 ml/100 g). Mucosal damage and pH were measured 1 h...

journal_title：Scandinavian journal of gastroenterology

authors： Ali AT

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:Patients with classic gastroesophageal reflux disease (GERD) symptoms and borderline 24-h pH studies are not considered to be good candidates for surgical fundoplication. Endoluminal gastroplication (ELGP) is a new endoscopic treatment for patients with GERD. The aim of this study was to evaluate the efficac...

journal_title：Scandinavian journal of gastroenterology

authors： Liu JJ,Carr-Locke DL,Lee LS,Brooks DC,Saltzman JR

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:In autoimmune hepatitis, data on the prognostic value of baseline liver biopsy and the sequential histology is controversial. Our aim was to evaluate the prognostic value of clinical variables and biopsy at the time of diagnosis and during the disease course. MATERIALS AND METHODS:All 98 patients in our hosp...

journal_title：Scandinavian journal of gastroenterology

authors： Puustinen L,Boyd S,Mustonen H,Arkkila P,Arola J,Färkkilä M

更新日期：2017-03-01 00:00:00

abstract：:Traditionally, gastro-oesophageal reflux is deemed to have occurred when oesophageal pH falls below 4. Other 'non-traditional' pH changes that do not fall below pH 4, that fall below 4 for only brief intervals, or that occur when basal pH is less than 4 are usually disregarded. The aim of this study was to determine w...

journal_title：Scandinavian journal of gastroenterology

authors： Wyman JB,Dent J,Holloway RH

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:The correlation of clinical and laboratory findings with various imaging techniques in obese patients is difficult. Colour duplex Doppler is of particularly limited value in fat individuals. The Doppler Perfusion Index (DPI) measures the ratio of hepatic arterial to total liver blood flow and seems to be mor...

journal_title：Scandinavian journal of gastroenterology

authors： Kakkos SK,Yarmenitis SD,Tsamandas AC,Gogos CA,Kalfarentzos F

更新日期：2000-09-01 00:00:00

abstract：:We report a rare case of Crohn disease accompanied by a small-bowel carcinoma that developed in a 54-year-old Japanese man. The ulcerating tumor, which histologically proved to be a poorly differentiated adenocarcinoma and dysplasia surrounding the carcinoma, was located in the diseased ileum. The Ki-67 immunoreactive...

journal_title：Scandinavian journal of gastroenterology

authors： Uesugi H,Mitomi H,Sada M,Takahashi H,Kobayashi K,Igarashi M,Katsumata T,Ihara A,Ohtani Y,Ikeda S,Okayasu I

更新日期：1999-11-01 00:00:00

abstract：:Gastrointestinal hormones are peptides released from neuroendocrine cells in the digestive tract. More than 30 hormone genes are currently known to be expressed in the gut, which makes it the largest hormone-producing organ in the body. Modern biology makes it feasible to conceive the hormones under five headings: The...

journal_title：Scandinavian journal of gastroenterology

authors： Rehfeld JF

更新日期：2015-06-01 00:00:00