Effect of the histamine H2-receptor antagonist, cimetidine, on gastric secretion and serum gastrin during insulin infusion in Man.

Abstract:

:Cimetidine infusion (100 mg h-1) reduced the acid secretory response to insulin infusion (0.03 units Kg-1h-1) when compared to paired control tests in 6 healthy volunteers. There was no significant difference between cimetidine and control tests in terms of pepsin output or serum gastrin concentrations. Cimetidine also reduced the acid secretory response when administered after 90 minutes of insulin had established a secretory response in extended tests in 3 additional volunteers. Cimetidine may have therapeutic potential in the peptic ulcer diathesis.

journal_name

Scand J Gastroenterol

authors

Carter DC,Forrest JA,Logan RA,Ansell I,Lidgard G,Heading RC,Shearman DJ

subject

Has Abstract

pub_date

1976-01-01 00:00:00

pages

565-70

issue

6

eissn

0036-5521

issn

1502-7708

journal_volume

11

pub_type

杂志文章
  • Acoustic radiation force impulse elastography and serum fibrosis markers in chronic hepatitis C.

    abstract:OBJECTIVE:Liver biopsy (LB) remains the gold standard for the assessment of liver fibrosis, although it is invasive and can have complications. The present study compares several noninvasive methods of fibrosis assessment in chronic hepatitis C (CHC), including acoustic radiation force impulse (ARFI) elastography, aspa...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2014.909528

    authors: Silva Junior RG,Schmillevitch J,Nascimento Mde F,Miranda ML,Brant PE,Schulz PO,Vieira A,Szutan LA

    更新日期:2014-08-01 00:00:00

  • Studies of the choledocho-duodenal sphincter in patients with and without juxta-papillary duodenal diverticula.

    abstract::The function of the choledocho-duodenal sphincter was studied in 16 patients, 8 with juxta-papillary duodenal diverticula. All patients had calculi in the gallbladder. The common bile duct was normal. At cholecystectomy two catheters were introduced into the common bile duct through the stump of the cystic duct and fi...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528009181545

    authors: Løtveit T,Osnes M,Aune S,Larsen S

    更新日期:1980-01-01 00:00:00

  • Pain produced by electric stimulation of the rectum in patients with irritable bowel syndrome: further evidence of visceral hyperalgesia.

    abstract:BACKGROUND:Visceral hyperalgesia is most likely a phenomenon of substantial clinical importance and may also play a role in the pathophysiology of the irritable bowel syndrome (IBS). We investigated the manifestation of visceral hyperalgesia in IBS patients by nociceptive electric stimulation of the rectosigmoid juncti...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655299750025101

    authors: Rössel P,Drewes AM,Petersen P,Nielsen J,Arendt-Nielsen L

    更新日期:1999-10-01 00:00:00

  • Outcome for biliary atresia patients treated at a low-volume centre.

    abstract:OBJECTIVES:The importance of case load for treatment of extrahepatic biliary atresia (BA) is debated. The aim of this study was to register results of BA treatment in a small volume centre. METHODS:Retrospective chart review study of patients with BA treated from 2000 to 2017. The institutional review board approved t...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2018.1439097

    authors: Bjørnland K,Hinna M,Aksnes G,Stensrud KJ,Ertresvåg K,Bjørnstad-Østensen A,Sanengen T,Line PD,Aagenæs I,Aabakken L,Emblem R,Almaas R

    更新日期:2018-04-01 00:00:00

  • The diagnostic value of the D-xylose absorption test in adult coeliac disease.

    abstract::The 25-g D-xylose absorption test was assessed in a total of 40 adult patients with coeliac disease before and after treatment and in 25 control patients. Because of a large overlap neither the urinary excretion rates nor the 1-h blood concentrations were of any use in the assessment of the individual patients. The ov...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528708996467

    authors: Bodé S,Gudmand-Høyer E

    更新日期:1987-12-01 00:00:00

  • Psychological factors in irritable bowel syndrome: a population-based study of patients, non-patients and controls.

    abstract:BACKGROUND:It has been suggested that psychopathology in irritable bowel syndrome (IBS) patients is a function of patient status rather than of the disease. Although there are many studies comparing IBS patients, IBS non-patients, and controls with each other, no previous study has recruited all three groups from a rep...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Weinryb RM,Osterberg E,Blomquist L,Hultcrantz R,Krakau I,Asberg M

    更新日期:2003-05-01 00:00:00

  • Testing strategies to reduce morbidity and mortality from Lynch syndrome.

    abstract:OBJECTIVE:Lynch syndrome (LS) has an autosomal dominant inheritance pattern and is associated with increased risk for colorectal cancer (CRC) and other cancers. Various strategies are used to identify patients at risk and offer surveillance and preventive programs, the cost effectiveness of which is much dependent on t...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.1080/00365521.2018.1542453

    authors: Keränen A,Ghazi S,Carlson J,Papadogiannakis N,Lagerstedt-Robinson K,Lindblom A

    更新日期:2018-12-01 00:00:00

  • Relevance of abdominal gas analysis and transit study after colorectal cancer surgery.

    abstract:BACKGROUND:Colon gas volume analysis using abdominal radiographs is an objective and reproducible method for evaluating functional bowel disorders. The aim of this study was to clarify the relevance of colon gas distribution and transit time in rectosigmoid cancer patients after surgery. METHODS:Segmental colon gas vo...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520310000898

    authors: Seike K,Koda K,Oda K,Kondo E,Ishizuka M,Miyazaki M

    更新日期:2003-04-01 00:00:00

  • Intestinal metaplasia at the gastroesophageal junction is associated with gastroesophageal reflux but not with Helicobacter pylori infection.

    abstract:OBJECTIVE:Studies of the etiology of intestinal metaplasia (IM) at a normal appearing gastroesophageal junction (GEJ) are conflicting as associations with both H. Pylori (HP) infection and gastroesophageal reflux has been reported. The aim of this study was to investigate whether IM at the GEJ is associated with gastro...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2018.1526967

    authors: Hall M,Wenner J,Scherman P,Öberg S

    更新日期:2018-01-01 00:00:00

  • Bacterial contamination of the small bowel evaluated by breath tests, 75Se-labelled homocholic-tauro acid, and scanning electron microscopy.

    abstract::Eighty-one patients with diarrhoea due to suspected bacterial contamination of the small intestine were investigated with the bile acid breath test (BABT) and 75Se-labelled homocholic-tauro acid (SeHCAT). The impact of bile acid malabsorption due to dysfunction of the terminal ileum on BABT was evaluated. The group of...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529008999224

    authors: Suhr O,Danielsson A,Hörstedt P,Stenling R

    更新日期:1990-08-01 00:00:00

  • Propofol combined with traditional sedative agents versus propofol- alone sedation for gastrointestinal endoscopy: a meta-analysis.

    abstract:OBJECTIVE:To assess the efficacy and safety of sedation of propofol combined with traditional sedative agents (PTSA) for gastrointestinal endoscopy, we conducted a meta-analysis of randomized controlled trials (RCTs) comparing PTSA with propofol-alone sedation. MATERIAL AND METHODS:RCTs comparing the effects of PTSA a...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,meta分析

    doi:10.3109/00365521.2012.737360

    authors: Wang D,Wang S,Chen J,Xu Y,Chen C,Long A,Zhu Z,Liu J,Deng D,Chen J,Tang D,Wang L

    更新日期:2013-01-01 00:00:00

  • Minimal liver disease in young persons with homozygous and heterozygous alpha-1-antitrypsin deficiency.

    abstract::Of 120 patients who were investigated for moderately elevated liver function tests as the only sign of liver disease, 6 young persons had alpha-1-antitrypsin (AAT) deficiency. Three had a homozygous (Pi ZZ) and three had a heterozygous (Pi MZ) AAT deficiency as measured with isoelectric focusing. An extensive investig...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Hultcrantz R,Jelf E,Nilsson LH

    更新日期:1984-05-01 00:00:00

  • Adaptive protection related to clearance of ethanol in gastric mucosa of cats.

    abstract::This study was designed to test the hypothesis that hyperemia after exposure to 2 M NaCl protects the gastric mucosa against damage caused by absolute ethanol by removing ethanol diffusing from the gastric lumen into the mucosa. The stomach of anesthetized cats was perfused with saline at pH 1.0. Gastric mucosal blood...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529309090257

    authors: Gislason H,Herfjord JK,Guttu K,Grong K,Grønbech JE,Ulvik R,Svanes K

    更新日期:1993-04-01 00:00:00

  • Wide gastric antrum in patients with non-ulcer dyspepsia. Effect of cisapride.

    abstract::Fasting antral area was examined by ultrasonography in 40 healthy subjects and in 106 patients with non-ulcer dyspepsia (NUD) and erosive prepyloric changes (EPC) before and after treatment with cisapride or placebo. The patients were examined twice, first after a run-in period of 14 days of placebo and then after 14 ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.3109/00365529209000100

    authors: Hausken T,Berstad A

    更新日期:1992-05-01 00:00:00

  • Helicobacter pylori and different topographic types of gastritis: treatment response after successful eradication therapy in functional dyspepsia.

    abstract:BACKGROUND:Helicobacter pylori gastritis is usually a lifelong disease which can cause different topographical inflammatory reactions and induce divergent effects on acid secretion in humans. High acid output and antrum-predominant gastritis are associated with duodenal ulcer disease, whereas corpus-predominat gastriti...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Koskenpato J,Färkkilä M,Sipponen P

    更新日期:2002-07-01 00:00:00

  • Contribution of intraoperative colonoscopy in a colorectal surgery unit.

    abstract:OBJECTIVES:Intraoperative colonoscopy (IC) is routinely used in colorectal surgery procedures, both oncologic and benign ones. Despite its extensive use there is a lack of literature addressing this important issue. The aims of this paper are to determine the contributions of this tool, especially considering changes i...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2017.1362465

    authors: Cerdán Santacruz C,Esteban López-Jamar JM,Sánchez López E,Cerdán Miguel J

    更新日期:2017-11-01 00:00:00

  • Modulation of arachidonic acid metabolism by olsalazine and other aminosalicylates in leukocytes.

    abstract::We investigated the action of the new aminosalicylate olsalazine (disodium azodisalicylate) on arachidonic acid metabolism in comparison with 5-aminosalicylic acid (5-ASA) and sulphasalazine (SASP) by in vitro incubation of cellular homogenates from human polymorphonuclear (PMNL) and mononuclear (MNL) leukocytes with ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529109037024

    authors: Horn H,Preclik G,Stange EF,Ditschuneit H

    更新日期:1991-08-01 00:00:00

  • Nephrotic syndrome in ulcerative colitis.

    abstract::Complicating disorders in various organs outside the intestinal tract are common in ulcerative colitis. This report deals with the occurrence of nephrotic syndrome in two patients with long-standing ulcerative colitis. In the patient studied in most detail, 2 episodes have taken place, the first developing into uremia...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Stokke KT,Teisberg PA,Myhre E,Hovig T,Flatmark A,Gjone E

    更新日期:1976-01-01 00:00:00

  • Effect of mental stress and cisapride on autonomic nerve functions in functional dyspepsia.

    abstract:BACKGROUND:Disordered autonomic nerve function is frequently present in patients with functional dyspepsia (FD). In this study we investigated whether the prokinetic cisapride, which acts via acetylcholine receptors, and stress may modulate these abnormalities. METHODS:Nineteen patients (6 men, 13 women) with FD and 1...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1080/00365529850166824

    authors: Hveem K,Svebak S,Hausken T,Berstad A

    更新日期:1998-02-01 00:00:00

  • The SHA2PE score: a new score for lower gastrointestinal bleeding that predicts low-risk of hospital-based intervention.

    abstract:OBJECTIVES:Lower gastrointestinal bleeding (LGIB) risk scores have mainly focused on identifying high-risk patients. A risk score aimed at predicting which patients will not require hospital-based intervention may reduce unnecessary hospital admissions. The aim of the current study was to develop such a risk score. MA...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2018.1532019

    authors: Hreinsson JP,Sigurdardottir R,Lund SH,Bjornsson ES

    更新日期:2018-12-01 00:00:00

  • Inhibitory effects of terbutaline on human esophageal peristalsis and development of tolerance.

    abstract::To investigate the inhibitory influence on esophageal motility of prolonged beta-2-adrenergic stimulation, esophageal peristalsis was studied in 10 volunteers. The beta-2 agonist terbutaline was given orally, 5 mg three times daily, for 10 days, and the subjects were studied before medication (basal), on days 3 and 10...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529309103133

    authors: Lyrenäs E,Sand C,Abrahamsson H

    更新日期:1993-10-01 00:00:00

  • Evaluation of the secretin-cholecystokinin test for chronic pancreatitis by discriminant analysis.

    abstract::Discriminant analysis was used to interpret the results of the secretin-cholecystokinin (CCK) test in the diagnosis of chronic pancreatitis. An allocation rule based on the use of two test variables--mean chymotrypsin concentration and peak bicarbonate output--was constructed to distinguish between 63 patients with ch...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528609034618

    authors: Heij HA,Obertop H,Schmitz PI,van Blankenstein M,Westbroek DL

    更新日期:1986-01-01 00:00:00

  • Psychological Factors in Irritable Bowel Syndrome: a Population-based Study of Patients, Non-patients and Controls.

    abstract:BACKGROUND:It has been suggested that psychopathology in irritable bowel syndrome (IBS) patients is a function of patient status rather than of the disease. Although there are many studies comparing IBS patients, IBS non-patients, and controls with each other, no previous study has recruited all three groups from a rep...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520310002166

    authors: Weinryb RM,Österberg E,Blomquist L,Hultcrantz R,Krakau I,Åsberg M

    更新日期:2003-01-01 00:00:00

  • Gut microflora associated characteristics in first-degree relatives of children with celiac disease.

    abstract:OBJECTIVE:In celiac disease (CD), enteropathy of the small bowel results from a T-cell-mediated reaction to gluten in the diet. In addition to gluten, other environmental and genetic factors participate in the disease pathogenesis. We have recently reported the finding of a significantly different short-chain fatty aci...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520701320687

    authors: Tjellström B,Stenhammar L,Högberg L,Fälth-Magnusson K,Magnusson KE,Midtvedt T,Sundqvist T,Houlston R,Popat S,Norin E

    更新日期:2007-10-01 00:00:00

  • Spontaneous splenic rupture precipitated by cough: a case report and a review of the literature.

    abstract::Spontaneous rupture of a normal spleen without a history of trauma is a rare clinical entity. We report on a case of atraumatic splenic rupture in a 61-year-old man who presented to the emergency department for abdominal pain and hypotension. There was no evidence of hematologic or infectious disease involving the spl...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1080/00365520701763472

    authors: Wehbe E,Raffi S,Osborne D

    更新日期:2008-01-01 00:00:00

  • Sliding gastric hiatal hernia diagnosis by transabdominal ultrasonography: an easy, reliable and non-invasive procedure.

    abstract:OBJECTIVE:Data in the literature suggest the possibility of using ultrasonography to diagnose sliding gastric hiatal hernia. The aim of this study was to confirm the diagnostic accuracy of transabdominal ultrasonography for the diagnosis of sliding gastric hiatal hernia, using endoscopy as the reference test. The latte...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520500453408

    authors: Barone M,Di Lernia P,Carbonara M,Ladisa R,Donno A,Amoruso A,Di Leo A,Francavilla A

    更新日期:2006-07-01 00:00:00

  • Correlation between pouch function and sexual function in patients with IPAA.

    abstract:OBJECTIVE:Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the treatment of choice for ulcerative colitis refractory to medical treatment and familial adenomatous polyposis. The objective of this study was to study the impact of postoperative pouch function on sexual function. Sexual function aft...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2015.1093165

    authors: Sunde ML,Øresland T,Engebreth Færden A

    更新日期:2016-03-01 00:00:00

  • The course of Helicobacter pylori infection in kidney transplantation patients.

    abstract:BACKGROUND:Helicobacter pylori has been found to be only a minor risk factor for gastroduodenal complications in kidney transplantation patients. The aim of the study was to follow up the course of H. pylori infection in a group of immunosuppressed kidney transplantation patients. METHODS:After a median follow-up of 6...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2003.11800652

    authors: Sarkio S,Rautelin H,Halme L

    更新日期:2003-01-01 00:00:00

  • The association between non-ulcer dyspepsia and other gastrointestinal disorders.

    abstract::Non-ulcer dyspepsia (NUD) is defined as dyspepsia in which investigation shows no evidence of focal gastroduodenal disease or oesophagitis. The aim of the present study was to determine the proportion of NUD patients with other identifiable diseases. We interviewed 327 consecutive patients who had at least 1 month of ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528509088842

    authors: Talley NJ,Piper DW

    更新日期:1985-09-01 00:00:00

  • Interactions of cholecystokinin (CCK-PZ) and gastrin on motor activity of isolated guinea-pig antrum and fundus.

    abstract::Pressure responses to cholecystokinin (CCK-PZ, approximately 500 U/mg) and gastrin (human synthetic gastrin) were investigated in isolated guinea-pig antral and fundal pouches. Both drugs stimulated motor activity, in the antrum mainly by increasing amplitudes and rhythmic activity, in the fundus by increasing basal t...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365527809182192

    authors: Gerner T,Haffner JF

    更新日期:1978-01-01 00:00:00