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Psychological factors in irritable bowel syndrome: a population-based study of patients, non-patients and controls.

Abstract：

BACKGROUND:It has been suggested that psychopathology in irritable bowel syndrome (IBS) patients is a function of patient status rather than of the disease. Although there are many studies comparing IBS patients, IBS non-patients, and controls with each other, no previous study has recruited all three groups from a representative community sample and had all subjects diagnosed by a physician. In the present study we aimed to compare psychological factors in IBS patients, IBS non-patients, and normal controls in a sample recruited from the population. METHODS:Subjects aged 18-45 years were recruited from a random sample of the normal population. Seventeen (2 M and 15 F) IBS patients were matched by sex and age with IBS non-patients and normals. Measures of personality traits, interpersonal distress, and temporary psychological distress were used. A physician diagnosed all 51 subjects in order to exclude possible gastrointestinal diagnoses other than IBS. RESULTS:Controls often differed from IBS non-patients and patients on the personality, interpersonal, and psychological distress measures, while IBS non-patients and patients very rarely differed from each other. All three groups were non-alexithymic. CONCLUSIONS:The results indicate that there are psychopathological differences between normals and IBS persons (patients and non-patients), but they could not confirm that psychopathology was a function of patient status. Whether this psychopathology is a vulnerability factor for IBS, or a consequence of it, remains to be studied.

journal_name

Scand J Gastroenterol

journal_title

Scandinavian journal of gastroenterology

authors

Weinryb RM,Osterberg E,Blomquist L,Hultcrantz R,Krakau I,Asberg M

subject

Has Abstract

pub_date

2003-05-01 00:00:00

pages

503-10

issue

5

eissn

0036-5521

issn

1502-7708

journal_volume

38

pub_type

临床试验,杂志文章,随机对照试验

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