The new prophylactic strategy for colon cancer in inflammatory bowel disease by modulating microbiota.

Abstract:

:It is well understood that intestinal microbiota play an important role in the pathogenesis of inflammatory bowel disease (IBD). In addition, IBD patients are well known to have a higher risk of developing colon cancer due to chronic inflammation. Recent evidence suggests that manipulation of microbiota improves the clinical outcome of patients with IBD and may reduce onset of colon cancer without obvious toxicity. This review summarizes the current experimental and clinical knowledge about the role of intestinal microbiota in IBD and colon cancer, and the nutraceutical therapy for colon cancer.

journal_name

Scand J Gastroenterol

authors

Kanauchi O,Mitsuyama K,Andoh A

doi

10.3109/00365521.2012.741617

subject

Has Abstract

pub_date

2013-04-01 00:00:00

pages

387-400

issue

4

eissn

0036-5521

issn

1502-7708

journal_volume

48

pub_type

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