Nephrotic syndrome in ulcerative colitis.

Abstract:

:Complicating disorders in various organs outside the intestinal tract are common in ulcerative colitis. This report deals with the occurrence of nephrotic syndrome in two patients with long-standing ulcerative colitis. In the patient studied in most detail, 2 episodes have taken place, the first developing into uremia. After colectomy had been performed, rapid improvement of renal function took place. The morphological changes in kidney biopsies were compatible with the presence of focal glomerular sclerosis. Activity in the complement system and a favorable response to steroid treatment indicate that humoral immune mechanisms are of pathogenetic importance with regard to the renal disease in these two patients. To our knowledge nephrotic syndrome has not previously been described as a complication to ulcerative colitis.

journal_name

Scand J Gastroenterol

authors

Stokke KT,Teisberg PA,Myhre E,Hovig T,Flatmark A,Gjone E

subject

Has Abstract

pub_date

1976-01-01 00:00:00

pages

571-6

issue

6

eissn

0036-5521

issn

1502-7708

journal_volume

11

pub_type

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