Polymorphonuclear function in patients with skin and joint symptoms after small-intestinal shunt operations.

Abstract:

:Previous studies have shown that the small-bowel shunt operation for morbid obesity may be followed by signs of enhanced cell-mediated immunity and polymorphonuclear (PMN) granulocyte bactericidal capacity. In the present study seven patients, operated 4 months--4.5 years previously and exhibiting postoperative arthralgias, arthritis, and/or skin rashes, were investigated with regard to their PMN adherence and bactericidal capacity and plasma levels of complement factors 3 and 4 (C3 and C4). There patients showed a decreased PMN bactericidal capacity compared both with 10 other shunt-operated patients without skin and joint symptoms and with healthy controls, whereas PMN adherence was lower than for the non-symptomatic patients but similar to that of the controls. Two patients had C3 levels above the reference value; all had normal C4 values. Thus, a small-bowel shunt operation for obesity, complicated by skin and joint symptoms, might be associated with decreased PMN bactericidal capacity.

journal_name

Scand J Gastroenterol

authors

Palmblad J,Engstedt L,Hallberg D,Norberg R,Udén AM

doi

10.3109/00365528009181476

subject

Has Abstract

pub_date

1980-01-01 00:00:00

pages

315-9

issue

3

eissn

0036-5521

issn

1502-7708

journal_volume

15

pub_type

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