Repeated pentagastrin-stimulated gastric acid secretory tests carried out in the evaluation of the pharmacodynamics of a new histamine H2-receptor antagonist, SK&F 93479.

abstract：BACKGROUND:The aims of the study were to assess the causes of jaundice in Gothenburg, Sweden, to study the types of investigations applied in cholestatic and hepatocellular types of jaundice and treatment and to evaluate the prognosis of these patients up to a year from the diagnosis. METHODS:Over a 3-month period, al...

journal_title：Scandinavian journal of gastroenterology

authors： Björnsson E,Ismael S,Nejdet S,Kilander A

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:The DNA mismatch repair gene mutations underlying hereditary non-polyposis colorectal cancer syndrome (HNPCC) also predispose, besides colorectal and endometrial cancer, to gastric cancer. usually of the intestinal type. The carcinogenetic pathway behind the elevated gastric cancer risk is largely unknown. ...

journal_title：Scandinavian journal of gastroenterology

authors： Renkonen-Sinisalo L,Sipponen P,Aarnio M,Julkunen R,Aaltonen LA,Sarna S,Järvinen HJ,Mecklin JP

更新日期：2002-05-01 00:00:00

abstract：:Eight patients with the foregut carcinoid syndrome (two gastric and six bronchial primary tumors) are reported. The patients presented with complex clinical symptoms including ectopic production of adrenocorticotrophic hormone and growth hormone-releasing factors. The most alarming symptoms were facial flush and edema...

journal_title：Scandinavian journal of gastroenterology

authors： Ahlman H,Wängberg B,Nilsson O,Grimelius L,Granérus G,Modlin IM,Stenqvist O,Scherstén T

更新日期：1992-06-01 00:00:00

abstract：:Pure human pancreatic phospholipase A2 efficiently hydrolyzed the 2-ester bond of 14C-2-linoleoyl and 14C-2-arachidonyl phosphatidylinositol (PI). The rate of hydrolysis varied markedly with the bile salt (sodium taurocholate to sodium taurodeoxycholate, 3:4 mol/mol) concentration, the hydrolysis being decreased with ...

journal_title：Scandinavian journal of gastroenterology

authors： Barros H,Sternby B,Nilsson A

更新日期：1990-02-01 00:00:00

abstract：:Objective: Endoscopy is the main method to treat gastrointestinal neuroendocrine tumors (GI-NETs), but the specific indications are still controversial. We aim to investigate the clinical outcomes of GI-NETs patients who experienced endoscopic submucosal dissection (ESD). Methods: We retrospectively reviewed the clini...

journal_title：Scandinavian journal of gastroenterology

authors： Chen X,Li B,Wang S,Yang B,Zhu L,Ma S,Wu J,He Q,Zhao J,Zheng Z,Li S,Wang T,Liang L

更新日期：2019-03-01 00:00:00

abstract：:In the present study the influence of duodenal exclusion and vagotomy on basal release of gastrin from extra-antral stores has been investigated in addition to the consequences of these procedures on the gastrin response to gastrin-releasing peptide (GRP) infusion. Basal gastrin concentrations and the response to GRP ...

journal_title：Scandinavian journal of gastroenterology

authors： Sjövall M,Lundell L,Rehfeld JF,Olbe L

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Electronic health (eHealth) solutions may help address the growing pressure on IBD outpatient services as they encompass a component of self-management. However, information regarding patients' attitudes towards the use of eHealth solutions in IBD is lacking. OBJECTIVE:The aim of this study was to evaluate ...

journal_title：Scandinavian journal of gastroenterology

authors： Con D,Jackson B,Gray K,De Cruz P

更新日期：2017-09-01 00:00:00

abstract：:Spontaneous rupture of a normal spleen without a history of trauma is a rare clinical entity. We report on a case of atraumatic splenic rupture in a 61-year-old man who presented to the emergency department for abdominal pain and hypotension. There was no evidence of hematologic or infectious disease involving the spl...

journal_title：Scandinavian journal of gastroenterology

authors： Wehbe E,Raffi S,Osborne D

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Gastrointestinal angiodysplasias (GIAD) bleeding and obscure gastrointestinal bleeding (OGIB) are increasing health problems. Somatostatin analogues have been proposed as rescue therapy, but data for lanreotide are scarce. OBJECTIVE:To determine the efficacy, safety and resource saving of long-acting lanreo...

journal_title：Scandinavian journal of gastroenterology

authors： Frago S,Alcedo J,Martín Pena-Galo E,Lázaro M,Ollero L,de la Llama N

更新日期：2018-12-01 00:00:00

abstract：:When 20 ml of 50 mmol/l pure synthetic bile salts (pH 6.5), of approximately the same composition as human bile, were infused into the duodenum of six healthy volunteers over 5 min during constant gastric aspiration, plasma immunoreactive secretin increased from 2.5 +/- 0.4 pmol/l to 3.6 +/- 0.5 pmol/l at 10 min (p < ...

journal_title：Scandinavian journal of gastroenterology

authors： Hanssen LE

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:Tumor necrosis factor alpha (TNF alpha) and beta (TNF beta) appear to play an important role in the regulation of the inflammatory response. The aim of the present study was to investigate the intrinsic capacity of peripheral blood mononuclear cells (PBMC) to produce these cytokines. METHODS:PBMC from 41 pa...

journal_title：Scandinavian journal of gastroenterology

authors： Bouma G,Oudkerk Pool M,Scharenberg JG,Kolkman JJ,von Blomberg BM,Scheper RJ,Meuwissen SG,Peña AS

更新日期：1995-11-01 00:00:00

abstract：:The isoamylases in various human tissue homogenates and body fluids were separated by agarose gel electrophoresis. Nothing suggested any significant production of amylase in the liver. Minute amounts of amylase belonging to the pancreatic group of isoamylases might be produced by the glands of the proximal duodenum. T...

journal_title：Scandinavian journal of gastroenterology

authors： Skude G

更新日期：1975-01-01 00:00:00

abstract：:The faecal excretion of short-chain fatty acids (SCFAs) has been measured in groups of six healthy subjects before, during, and after they received the antibiotics clindamycin, ampicillin, or metronidazole perorally for 6 days. Intake of clindamycin reduced the median total concentration of SCFAs from 62.9 mmol/kg fae...

journal_title：Scandinavian journal of gastroenterology

authors： Høverstad T,Carlstedt-Duke B,Lingaas E,Midtvedt T,Norin KE,Saxerholt H,Steinbakk M

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:Plasminogen activators (PA) may be released by the gut and eliminated by the liver. Patients with liver disorders or malignancy often have abnormal plasma levels of PAs. Some tumours may produce PAs. METHODS:In patients undergoing gastric surgery for malignant (n = 18) or benign (n = 21) disorders., blood d...

journal_title：Scandinavian journal of gastroenterology

authors： Rahr HB,Sørensen JV,Larsen JF,Jensen FS,Bredahl C

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVES:Bile acid (BA) malabsorption may occur after cholecystectomy. Bile may flow more freely into the duodenum after endoscopic sphincterotomy (EST), in part resembling the situation after cholecystectomy. The (75)SeCHAT test used to diagnose BA malabsorption correlates inversely with synthesis and faecal excreti...

journal_title：Scandinavian journal of gastroenterology

authors： Ung KA,Mottacki N,Rudling M,Bajor A

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Activin A, the homodimer of the activin/inhibin betaA subunit, has been shown to participate in cutaneous wound healing. In this study we intended to determine its part in gastric ulceration. METHODS:Activin A expression was studied by immunohistochemistry and in situ hybridization in acetic-acid-induced ch...

journal_title：Scandinavian journal of gastroenterology

authors： Becker JC,Hertel M,Markmann A,Shahin M,Werner S,Domschke W,Pohle T

更新日期：2003-03-01 00:00:00

abstract：:The intragastric concentrations of bile acid (BAC) and pH were measured over 24 h in 13 patients with duodenal (DU), in 11 with prepyloric (PU) ulcer disease, and in 12 healthy controls. Large fluctuations in bile acid concentration occurred for individuals from all three groups. PU patients had BACs higher than DU pa...

journal_title：Scandinavian journal of gastroenterology

authors： Gotthard R,Bodemar G,Tjädermo M,Tobiasson P,Walan A

更新日期：1985-05-01 00:00:00

abstract：:Six pigs (49-69 kg) were anaesthetized and fitted with cannulas in the brachiocephalic artery and portal and jugular veins. In addition, inlet-outlet perfusion cannulas were placed in segments of the small and large intestine. Intravenous infusion of urea for 2 h increased arterial plasma urea from a base-line level o...

journal_title：Scandinavian journal of gastroenterology

authors： Malmlöf K,Simoes Nunes C

更新日期：1992-07-01 00:00:00

abstract：OBJECTIVE:There is increasing knowledge of the pathophysiology behind inflammatory bowel disease (IBD) although the exact mechanism is far from fully understood. In the era of new technology, over the last years molecular approaches have shed light on the inflammatory mechanisms and their metabolic end products. This o...

journal_title：Scandinavian journal of gastroenterology

authors： Florholmen J,Fries W

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Food intake, accompanied by systemic and splanchnic haemodynamic changes, has only been studied in males. The extent to which splanchnic postprandial hyperaemia shows gender differences is unknown. METHODS:We tested 1) the splanchnic hyperaemic response to food in females and 2) whether postprandial haemody...

journal_title：Scandinavian journal of gastroenterology

authors： Szinnai C,Mottet C,Gutzwiller JP,Drewe J,Beglinger C,Sieber CC

更新日期：2001-05-01 00:00:00

abstract：:Calcium absorption was studied in 23 patients before and one year after intestinal shunt operation for obesity. It decreased from 23 to 12% (p less than 0.02) after surgery, when the jejunum/ileum ratio was 36cm/12cm [type I], and only from 19 to 16% (p greater than 0.05), when the ratio was 12cm/36cm [type III]. It i...

journal_title：Scandinavian journal of gastroenterology

authors： Danö P,Christiansen C

更新日期：1978-01-01 00:00:00

abstract：:Histamine was given intravenously to eight human subjects, and the PP concentration in serum increased significantly from 14.8 (7.2-29.3) pM to 27.5 (9.6-39.3) pM and then decreased to the basal level. This histamine-induced PP release was not altered when trimipramine or cimetidine was given in addition to histamine....

journal_title：Scandinavian journal of gastroenterology

authors： Flaten O,Bohman T,Myren J

更新日期：1981-01-01 00:00:00

abstract：:Background and aim: Acute-on-chronic liver failure (ACLF) is characterized by the presence of acute decompensation (AD) of cirrhosis, organ failures, and high short-term mortality rates. In present study, we explored whether Pro-adrenomedullin (Pro-ADM), a biomarker of sepsis, is a potential marker of outcome in patie...

journal_title：Scandinavian journal of gastroenterology

authors： Yan H,Jin S,Liang L,Du J,Aithal GP,Li L

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Stimulation of gastric motility has been supposed to accelerate the healing of gastric ulcer. The combination of the prokinetic drug cisapride and the H2 blocker ranitidine was tested in the treatment of uncomplicated gastric ulcer. METHODS:Cisapride, 20 mg twice daily (Cis), and ranitidine, 150 mg twice da...

journal_title：Scandinavian journal of gastroenterology

authors： Stubberöd A,Glise H,Hallerbäck B,Solhaug JH

更新日期：1995-02-01 00:00:00

abstract：:A 48-year-old man presented with abdominal pain, constipation and irritability one month after starting phenytoin treatment for a generalized seizure. He was hypertensive, tachycardic (BP 174/98, heart rate (HR) 100 bpm supine) and hypovolaemic. Abdominal CT demonstrated transient jejunal intussusception and infarctio...

journal_title：Scandinavian journal of gastroenterology

authors： Griffith JC,Jardine DL,Bailey W,Florkowski CM

更新日期：2004-05-01 00:00:00

abstract：:Gastric microcirculatory changes were studied by means of hydrogen clearance techniques in conscious cats during histamine stimulation. A considerable increase of corpus mucosa flow occurred, whereas a less substantial increase of antrum mucosa flow was observed during stimulation with histamine at 2 micrograms/kg/min...

journal_title：Scandinavian journal of gastroenterology

authors： Semb BK

更新日期：1981-01-01 00:00:00

abstract：OBJECTIVE:Bile acids are derived from cholesterol and are potent physiological laxatives. The aim of this study was to investigate whether bile acid synthesis is altered in constipation. MATERIAL AND METHODS:Female patients with constipation (23 IBS-C, 4 functional constipation (FC)) were studied and compared with non...

journal_title：Scandinavian journal of gastroenterology

authors： Abrahamsson H,Ostlund-Lindqvist AM,Nilsson R,Simrén M,Gillberg PG

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:Common bile duct stenting is widely performed for bridging benign and malignant obstructions. A major limitation is early stent occlusion making regular stent exchange necessary. Covalent binding of glycosaminoglycanes to polyethylene stents proved to reduce encrustation in urological implants. Since developm...

journal_title：Scandinavian journal of gastroenterology

authors： Farnbacher MJ,Lederer R,Blana A,Schneider HT

更新日期：2012-10-01 00:00:00

abstract：:Fasting plasma levels of immunoreactive gastrin, somatostatin, and pancreatic polypeptide (PP) were determined in 67 patients with an endoscopically proven duodenal, pyloric, or prepyloric ulcer. Pretreatment gastrin (45.6 +/- 53.6 pmol/l, mean +/- S.D.) and somatostatin (54.5 +/- 27.5 pg/ml) did not differ significan...

journal_title：Scandinavian journal of gastroenterology

authors： Gustavsson S,Adami HO,Björklund O,Enander LK,Lundqvist G,Lööf L,Nordahl A

更新日期：1982-01-01 00:00:00

abstract：:Short-chain fatty acids (SCFA) originate mainly in the colon through bacterial fermentation of polysaccharides. To test the hypothesis that SCFA may originate from polypeptides as well, the production of these acids from albumin and specific amino acids was examined in a faecal incubation system. Albumin was converted...

journal_title：Scandinavian journal of gastroenterology

authors： Rasmussen HS,Holtug K,Mortensen PB

更新日期：1988-03-01 00:00:00