Abstract:
:The in vitro activity of sparfloxacin, a new fluoroquinolone, was compared with ciprofloxacin and ofloxacin against 166 consecutive isolates from the upper respiratory tract of outpatients. The strains were fully susceptible to three quinolones. The antibacterial activity of sparfloxacin was comparable or better than that of ofloxacin and ciprofloxacin against all strains. Sparfloxacin was fourfold more active against Staphylococcus aureus and Streptococcus pneumoniae. The favourable MIC values and a prolonged half-life makes sparfloxacin interesting for treating respiratory tract infections in out-patient care.
journal_name
Chemotherapyjournal_title
Chemotherapyauthors
Malmborg AS,Ahlén Sdoi
10.1159/000238970subject
Has Abstractpub_date
1993-01-01 00:00:00pages
32-5issue
1eissn
0009-3157issn
1421-9794journal_volume
39pub_type
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