Leukoaraiosis and dementia in hypertensive patients.

abstract：BACKGROUND AND PURPOSE:Efforts to reduce disparities in recurrent stroke among Black and Latino stroke survivors have met with limited success. We aimed to determine the effect of peer education on secondary stroke prevention among predominantly minority stroke survivors. METHODS:Between 2009 and 2012, we enrolled 600...

journal_title：Stroke

authors： Kronish IM,Goldfinger JZ,Negron R,Fei K,Tuhrim S,Arniella G,Horowitz CR

更新日期：2014-11-01 00:00:00

abstract：:The angiographic, clinical, and genetic characteristics of fibromuscular dysplasia (FMD) are reviewed in 37 patients (mean age 48 years) selected from a pool of 4000 angiograms of carotid or vertebral arteries. FMD was a neglected pathogenic factor in 28 patients with hemorrhagic or ischemic cerebral lesions. The aneu...

journal_title：Stroke

authors： Mettinger KL,Ericson K

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the physical and, to a lesser extent, emotional outcome of stroke survivors has been well documented, there are far fewer data relating to the outcomes of those who care for them. We aimed to describe the outcome of those caring for stroke patients and to identify both patient and caregi...

journal_title：Stroke

authors： Dennis M,O'Rourke S,Lewis S,Sharpe M,Warlow C

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Victims of air embolism often recover rapidly on hyperbaric treatment then deteriorate again, even if hyperbaric treatment is continued. In previous animal experiments, lidocaine has been shown to improve recovery of somatosensory evoked response amplitude after air embolism. However, animals in ...

journal_title：Stroke

authors： Dutka AJ,Mink R,McDermott J,Clark JB,Hallenbeck JM

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to investigate the mechanisms for oxidative injury caused by subarachnoid hemolysate, a pro-oxidant. METHODS:Injection of 50 microL of subarachnoid hemolysate or saline was performed in CD1 mice (n=75), mutant mice deficient in Mn-superoxide dismutase (Sod2+/-; n=23), and their wild-ty...

journal_title：Stroke

authors： Matz PG,Fujimura M,Lewen A,Morita-Fujimura Y,Chan PH

更新日期：2001-02-01 00:00:00

abstract：:The purpose of this work was to study the contractile activity of intracerebral microarterioles and their sensitivity to the calcium antagonist nimodipine. Potassium depolarization evoked contraction and rhythmic activity that was blocked by nimodipine (IC50 0.08 nM). High concentrations of noradrenaline and prostagla...

journal_title：Stroke

authors： Godfraind T,Morel N,Dessy C

更新日期：1990-12-01 00:00:00

abstract：:MRI is becoming the imaging modality of choice in patients with ischemic cerebrovascular disease although CT is still the test of choice to exclude acute hemorrhagic stroke. We have briefly reviewed characteristic features of ischemic and hemorrhagic cerebrovascular disease as well as vascular anomalies as seen on MRI...

journal_title：Stroke

authors： Ramadan NM,Deveshwar R,Levine SR

更新日期：1989-09-01 00:00:00

abstract：:Background and Purpose- Hyperglycemia is a negative prognostic factor after acute ischemic stroke but is not known whether glucose is associated with the effects of endovascular thrombectomy (EVT) in patients with large-vessel stroke. In a pooled-data meta-analysis, we analyzed whether serum glucose is a treatment mod...

journal_title：Stroke

authors： Chamorro Á,Brown S,Amaro S,Hill MD,Muir KW,Dippel DWJ,van Zwam W,Butcher K,Ford GA,den Hertog HM,Mitchell PJ,Demchuk AM,Majoie CBLM,Bracard S,Sibon I,Jadhav AP,Lara-Rodriguez B,van der Lugt A,Osei E,Renú A,Richard

更新日期：2019-03-01 00:00:00

abstract：:We measured cerebrovascular reactivity to carbon dioxide in the cerebral cortex and the subcortical white matter of 12 healthy adult volunteers (four young subjects aged 21-24, four middle-aged subjects aged 34-40, and four elderly subjects aged 62-85 years). Blood flow was computed from the concentration history of x...

journal_title：Stroke

authors： Reich T,Rusinek H

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thrombolytic therapy with recombinant tissue plasminogen activator (rtPA) after stroke increases risk of hemorrhagic transformation, particularly in areas with blood-brain barrier leakage. Our aim was to characterize acute effects of rtPA administration on the integrity of microvascular barriers....

journal_title：Stroke

authors： Dijkhuizen RM,Asahi M,Wu O,Rosen BR,Lo EH

更新日期：2002-08-01 00:00:00

abstract：:Results from 1,039 combined cervical and transcranial Doppler examinations are reported. Satisfactory transcranial signals were not found in 2.7% of the cases. Compared with angiography, the accuracy of transcranial criteria in assessing collateral flow over the circle of Willis was 94 and 88% for anterior and posteri...

journal_title：Stroke

authors： Grolimund P,Seiler RW,Aaslid R,Huber P,Zurbruegg H

更新日期：1987-11-01 00:00:00

abstract：:Many nonsteroidal anti-inflammatory drugs exert their effects by inhibiting the synthesis of prostanoids. More specifically, these agents block the synthesis of prostaglandin endoperoxide G2 from arachidonic acid by competing with arachidonate for binding to the cyclooxygenase active site of prostaglandin endoperoxide...

journal_title：Stroke

authors： Smith WL,DeWitt DL,Shimokawa T,Kraemer SA,Meade EA

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Aneurysmal subarachnoid hemorrhage (SAH) is a cerebrovascular disease with a high mortality rate and severe disability. Longitudinal studies investigating health-economic costs in SAH are scare and only one of them analyzed cost-driving factors. The objective was to evaluate first-year costs in G...

journal_title：Stroke

authors： Dodel R,Winter Y,Ringel F,Spottke A,Gharevi N,Müller I,Klockgether T,Schramm J,Urbach H,Meyer B

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Data from recent multicenter carotid endarterectomy trials have questioned the validity and reliability of Doppler ultrasound in the assessment of carotid stenosis. METHODS:We prospectively analyzed 45 patients undergoing carotid angiography to compare the North American Symptomatic Carotid Enda...

journal_title：Stroke

authors： Alexandrov AV,Bladin CF,Maggisano R,Norris JW

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The onset of spontaneous intracerebral hemorrhage (ICH) is often accompanied by transient blood pressure (BP) elevation. The prognostic value and the determinants of this BP reaction have not entirely been solved, and the present study was focused on these questions. METHODS:From 1985 to 1991 in...

journal_title：Stroke

authors： Fogelholm R,Avikainen S,Murros K

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The genetic basis of white matter hyperintensities (WMH) is still unknown. This study examines the heritability of WMH in both sexes and in different brain regions, and the influence of age. METHODS:Participants from the Older Australian Twins Study were recruited (n=320; 92 monozygotic and 68 d...

journal_title：Stroke

authors： Sachdev PS,Thalamuthu A,Mather KA,Ames D,Wright MJ,Wen W,OATS Collaborative Research Team.

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:On the assumption that the majority of lacunes are caused by small-vessel diseases and that pial artery infarcts arise from cardio-embolic or large-vessel diseases, 194 patients from the Berlin Cerebral Ischemia Data Bank with either lacunar or pial artery infarcts were analyzed for the frequency...

journal_title：Stroke

authors： Mast H,Thompson JL,Völler H,Mohr JP,Marx P

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke is the leading cause of adult disability worldwide. Currently, there is no effective treatment for stroke survivors. Stem cell factor (SCF) and granulocyte-colony stimulating factor (G-CSF) are the growth factors regulating hematopoiesis. We have previously observed that SCF and G-CSF have...

journal_title：Stroke

authors： Zhao LR,Berra HH,Duan WM,Singhal S,Mehta J,Apkarian AV,Kessler JA

更新日期：2007-10-01 00:00:00

abstract：:U78517F is a novel inhibitor of iron-catalyzed lipid peroxidation that combines the tetramethylchroman antioxidant ring portion of alpha-tocopherol with the amine of the previously described 21-aminosteroids (e.g., U74006F). U78517F inhibited 200 microM FeCl2-initiated lipid peroxidation in rat brain homogenates by 50...

journal_title：Stroke

authors： Hall ED,Pazara KE,Braughler JM,Linseman KL,Jacobsen EJ

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke-related physical disability can diminish quality of daily living, place care burden on families, and increase need for long-term institutionalization. We developed a prognostic index for use in research and with potential for adaptation to clinical practice that establishes the likelihood ...

journal_title：Stroke

authors： Stineman MG,Maislin G,Fiedler RC,Granger CV

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is still unclear that impaired cerebrovascular reactivity (CVR) to acetazolamide is comparable to elevated oxygen extraction fraction (OEF) on positron emission tomography (PET) in patients with occlusive carotid diseases. Therefore, in this study, the authors aimed to clarify whether OEF is e...

journal_title：Stroke

authors： Kuroda S,Shiga T,Houkin K,Ishikawa T,Katoh C,Tamaki N,Iwasaki Y

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Elevated soluble CD40 ligand (sCD40L) was shown to be related to cardiovascular events, but the role of sCD40L in predicting recurrent stroke remains unclear. METHODS:Baseline sCD40L levels were measured in 3044 consecutive patients with acute minor stroke and transient ischemic attack, who had ...

journal_title：Stroke

authors： Li J,Wang Y,Lin J,Wang D,Wang A,Zhao X,Liu L,Wang C,Wang Y,CHANCE Investigators.

更新日期：2015-07-01 00:00:00

abstract：:Background and Purpose- Blood pressure (BP) variability may increase the risk of stroke and dementia. It remains inconclusive whether BP variability is associated with cerebral small vessel disease, a common and potentially devastating subclinical disease that contributes significantly to both stroke and dementia. Met...

journal_title：Stroke

authors： Ma Y,Song A,Viswanathan A,Blacker D,Vernooij MW,Hofman A,Papatheodorou S

更新日期：2020-01-01 00:00:00

abstract：:A case of simultaneous rupture of two intracranial aneurysms is reported. This is a rare event, and we found no CT reports of such a case. This case points out that the usual assumption of a single aneurysm rupture in a patient with multiple aneurysms may be erroneous and difficult to diagnose angiographically, but ma...

journal_title：Stroke

authors： Joslyn JN,Williams JP,White JL,White RL

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Parental stroke has been related to an increased risk of stroke in the offspring. This study examines whether parental stroke is also associated with increased vascular brain injury and poorer cognitive performance among offspring free of clinical stroke. METHODS:Multivariable regression analyse...

journal_title：Stroke

authors： Weinstein G,Beiser AS,Au R,Decarli C,Wolf PA,Seshadri S

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Research has identified a number of factors associated with poststroke recovery, but the prediction of long-term functional outcome remains an uncertain endeavor. In previous work, extinction to tactile, double-simultaneous stimulation has been shown to have short-term predictive utility. The pre...

journal_title：Stroke

authors： Rose L,Bakal DA,Fung TS,Farn P,Weaver LE

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Data on safety of intravenous thrombolysis with recombinant tissue-type plasminogen activator for acute ischemic stroke in patients with coexisting cerebral cavernous malformations (CCMs) are scarce. We assessed the risk of thrombolysis-associated hemorrhage in these patients. METHODS:We searche...

journal_title：Stroke

authors： Erdur H,Scheitz JF,Tütüncü S,Fiebach JB,Endres M,Werring DJ,Nolte CH

更新日期：2014-06-01 00:00:00

abstract：:Functional assessment of animals following experimental cerebral ischemia is often difficult due to the passive nature of many neurologic exams. We attempted to increase the objectivity of motor function evaluation by adapting quantifiable behavioral tests and actively testing rats' motor capability following a cerebr...

journal_title：Stroke

authors： Combs DJ,D'Alecy LG

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Fibrinogen is an independent risk factor for coronary events in population-based studies and in patients with coronary heart disease, but there is uncertainty about prediction of stroke, particularly in secondary prevention. METHODS:We studied unpublished data from 3 prospective studies of patie...

journal_title：Stroke

authors： Rothwell PM,Howard SC,Power DA,Gutnikov SA,Algra A,van Gijn J,Clark TG,Murphy MF,Warlow CP

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To assess the role of the endothelial nitric oxide synthase (eNOS) gene variants as risk factors for early atherosclerosis, we sought to investigate whether two polymorphisms located in the exon 7 (Glu298-->Asp) and in the promoter region (T-786-->C) of the eNOS gene were associated with function...

journal_title：Stroke

authors： Paradossi U,Ciofini E,Clerico A,Botto N,Biagini A,Colombo MG

更新日期：2004-06-01 00:00:00