Cardiac sources of embolism in patients with pial artery infarcts and lacunar lesions.

Abstract:

BACKGROUND AND PURPOSE:On the assumption that the majority of lacunes are caused by small-vessel diseases and that pial artery infarcts arise from cardio-embolic or large-vessel diseases, 194 patients from the Berlin Cerebral Ischemia Data Bank with either lacunar or pial artery infarcts were analyzed for the frequency of cardiac sources of embolism. The primary hypothesis was that the frequency of cardiac sources of embolism is higher among pial artery infarct subjects. METHODS:The presence of cardiac sources of embolism was estimated by electrocardiographic and transthoracic and transesophageal echocardiographic studies. Cranial computed tomography scans were evaluated by two masked observers. RESULTS:The overall rate of cardiac sources of embolism did not differ significantly between the lacunar and the pial artery infarct group (66% versus 71%; odds ratio, 0.80; confidence interval, 0.43 to 1.50). Echocardiographic evidence of cardiac thrombi was positively associated with pial artery infarcts (odds ratio, 0.18; confidence interval, 0.04 to 0.80); atrial fibrillation and all other cardiac sources were not. CONCLUSIONS:Left cardiac thrombi are significantly associated with pial artery infarcts. Other presumed cardiac sources of embolism, including atrial fibrillation, may often represent coincidental findings or have a less strong tendency to result in pial artery infarcts.

journal_name

Stroke

journal_title

Stroke

authors

Mast H,Thompson JL,Völler H,Mohr JP,Marx P

doi

10.1161/01.str.25.4.776

subject

Has Abstract

pub_date

1994-04-01 00:00:00

pages

776-81

issue

4

eissn

0039-2499

issn

1524-4628

journal_volume

25

pub_type

杂志文章

相关文献

STROKE文献大全
  • Human serum albumin and its N-terminal tetrapeptide (DAHK) block oxidant-induced neuronal death.

    abstract:BACKGROUND AND PURPOSE:Studies using animal models of stroke have shown that human serum albumin (HSA) significantly ameliorates cerebral ischemic injury after both transient and permanent ischemia, even when administered after the onset of ischemia or reperfusion. The mechanism of this effect remains uncertain, and pr...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000110790.05859.DA

    authors: Gum ET,Swanson RA,Alano C,Liu J,Hong S,Weinstein PR,Panter SS

    更新日期:2004-02-01 00:00:00

  • Estimation of error limits for cerebral blood flow values obtained from xenon-133 clearance curves.

    abstract::I provide the theoretical basis for an error calculus for measurements of cerebral blood flow using a freely diffusible tracer substance such as xenon-133. The use of the error calculus is exemplified by a study of the effect on the error margins in measurements of gray matter blood flow from flow level, relative weig...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.20.2.205

    authors: Ryding E

    更新日期:1989-02-01 00:00:00

  • Cerebral oxygen metabolism and neuronal integrity in patients with impaired vasoreactivity attributable to occlusive carotid artery disease.

    abstract:BACKGROUND AND PURPOSE:It is still unclear that impaired cerebrovascular reactivity (CVR) to acetazolamide is comparable to elevated oxygen extraction fraction (OEF) on positron emission tomography (PET) in patients with occlusive carotid diseases. Therefore, in this study, the authors aimed to clarify whether OEF is e...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000198878.66000.4e

    authors: Kuroda S,Shiga T,Houkin K,Ishikawa T,Katoh C,Tamaki N,Iwasaki Y

    更新日期:2006-02-01 00:00:00

  • Complication rates and center enrollment volume in the carotid revascularization endarterectomy versus stenting trial.

    abstract:BACKGROUND AND PURPOSE:Evidence indicates that center volume of cases affects outcomes for both carotid endarterectomy and stenting. We evaluated the effect of enrollment volume by site on complication rates in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST). METHODS:The primary composite en...

    journal_title:Stroke

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1161/STROKEAHA.114.006228

    authors: Gonzales NR,Demaerschalk BM,Voeks JH,Tom M,Howard G,Sheffet AJ,Garcia L,Clair DG,Barr J,Orlow S,Brott TG,CREST Investigators.

    更新日期:2014-11-01 00:00:00

  • Ejection fraction response of the left ventricle of the heart to acute cerebrovascular accident in patients with coronary artery disease.

    abstract::The ejection fraction (EF) of the left ventricle was measured by radionuclide ventriculography in 64 patients during an acute cerebrovascular accident. Sixteen patients (12 with coronary artery disease) died within two weeks of the onset of symptoms and had only one EF measurement. In the remaining 48 patients, the EF...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.17.4.613

    authors: Front D,Frankel A,Israel O,Aharon Y,Satinger A,Linn S

    更新日期:1986-07-01 00:00:00

  • Cerebrovascular reactivity in comatose patients resuscitated from a cardiac arrest.

    abstract:BACKGROUND AND PURPOSE:Cerebral blood flow after cardiac arrest is reduced during the delayed hypoperfusion phase, while cerebral metabolic rate of oxygen returns to baseline values. Hypocapnia can induce cerebral ischemia in neurosurgical patients who already have reduced cerebral blood flow. The purpose of the presen...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.28.8.1569

    authors: Buunk G,van der Hoeven JG,Meinders AE

    更新日期:1997-08-01 00:00:00

  • Iron Overload Exacerbates the Risk of Hemorrhagic Transformation After tPA (Tissue-Type Plasminogen Activator) Administration in Thromboembolic Stroke Mice.

    abstract::Background and Purpose- Recanalization with tPA (tissue-type plasminogen activator) is the only pharmacological therapy available for patients with ischemic stroke. However, the percentage of patients who may receive this therapy is limited by the risk of hemorrhagic transformation (HT)-the main complication of ischem...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.118.021540

    authors: García-Yébenes I,García-Culebras A,Peña-Martínez C,Fernández-López D,Díaz-Guzmán J,Negredo P,Avendaño C,Castellanos M,Gasull T,Dávalos A,Moro MA,Lizasoain I

    更新日期:2018-09-01 00:00:00

  • Anterior choroidal artery territory infarcts. Study of presumed mechanisms.

    abstract:BACKGROUND AND PURPOSE:A previous study suggested that occlusive diseases of small penetrating arteries account for most anterior choroidal artery (AChA) territory infarcts, but half of the patients did not have an echocardiogram. Cases of AChA territory infarcts associated with internal carotid artery stenosis or atri...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.25.4.837

    authors: Leys D,Mounier-Vehier F,Lavenu I,Rondepierre P,Pruvo JP

    更新日期:1994-04-01 00:00:00

  • Interrater agreement in evaluation of stroke patients with the unified neurological stroke scale.

    abstract:BACKGROUND:We sought to determine interrater agreement in evaluation of stroke patients with the Unified Form for Neurological Stroke Scales (UFNSS). SUMMARY OF REPORT:Fifty inpatients were independently examined by three neurologists. Kendall coefficients of concordance were computed for the different items of the UF...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.25.6.1263

    authors: Treves TA,Karepov VG,Aronovich BD,Gorbulev AY,Bornstein NM,Korczyn AD

    更新日期:1994-06-01 00:00:00

  • Early diffusion-weighted MRI as a predictor of caspase-3 activation after hypoxic-ischemic insult in neonatal rodents.

    abstract:BACKGROUND AND PURPOSE:Neonatal encephalopathy in human babies is a serious condition associated with permanent neurological deficits. Diffusion-weighted MRI (DWI) is increasingly used for early diagnosis of brain injury in human babies. The relationship between the presence of DWI abnormalities and cellular injury, in...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.107.506352

    authors: Wendland MF,Faustino J,West T,Manabat C,Holtzman DM,Vexler ZS

    更新日期:2008-06-01 00:00:00

  • Lacunar syndrome due to intracerebral hemorrhage.

    abstract::It has been recognized that small intracerebral hemorrhage not uncommonly produced lacunar syndromes. In this study, we examined cases of intracerebral hemorrhage presenting as lacunar syndromes. Of 174 cases with recent intracerebral hemorrhage, 19 presented with a lacunar syndrome: 4 presented with pure motor hemipa...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.16.3.454

    authors: Mori E,Tabuchi M,Yamadori A

    更新日期:1985-05-01 00:00:00

  • Regional availability of mechanical embolectomy for acute ischemic stroke in California, 2009 to 2010.

    abstract:BACKGROUND AND PURPOSE:We sought to assess the geographic proximity of patients with stroke in California to centers that performed specific threshold volumes of mechanical embolectomy procedures each year. METHODS:We identified all patients who were hospitalized for acute ischemic stroke at all nonfederal acute care ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.114.007735

    authors: Choi JC,Hsia RY,Kim AS

    更新日期:2015-03-01 00:00:00

  • Functional changes in human pial arteries (300 to 900 micrometer ID) within 48 hours of aneurysmal subarachnoid hemorrhage.

    abstract:BACKGROUND AND PURPOSE:Animal studies of cerebral arteries 2 to 3 days after experimental subarachnoid hemorrhage (SAH) provide evidence of arterial change such as hyperresponsiveness to contractile agonists. There is evidence that small arteries, as well as those large enough to be seen on angiography, may be involved...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.29.12.2575

    authors: Bevan JA,Bevan RD,Walters CL,Wellman T

    更新日期:1998-12-01 00:00:00

  • Classification of Covert Brain Infarct Subtype and Risk of Death and Vascular Events.

    abstract::Background and Purpose- To test the hypothesis that covert brain infarcts (CBIs) are more likely to be located in noneloquent brain areas compared with clinical strokes and that CBI etiological subtypes carry a differential risk of vascular events compared with people without CBI. Methods- We used brain magnetic reson...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.119.026068

    authors: Gutierrez J,Gil-Guevara A,Ramaswamy S,DeRosa J,Di Tullio MR,Cheung K,Rundek T,Sacco RL,Wright CB,Elkind MSV

    更新日期:2020-01-01 00:00:00

  • Vasodilator proteins: role in delayed cerebral vasospasm.

    abstract::Blood proteins could play a critical role in the pathogenesis of cerebral vasospasm in subarachnoid hemorrhage (SAH) as agonists and as antagonists of vasoconstriction. The present study was designed primarily to quantify the inhibition produced by antithrombin III of the phasic responses elicited by cumulative doses ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.17.2.207

    authors: White RP

    更新日期:1986-03-01 00:00:00

  • Fatal infantile polyarteritis nodosa with predominant central nervous system involvement.

    abstract:BACKGROUND:Infantile polyarteritis nodosa usually presents in children under 2 years of age as a multiorgan system disease with signs of congestive heart failure or renal failure. This disease and Kawasaki disease may share certain clinical and pathological features. CASE DESCRIPTION:We describe a child who first pres...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.26.4.699

    authors: Engel DG,Gospe SM Jr,Tracy KA,Ellis WG,Lie JT

    更新日期:1995-04-01 00:00:00

  • Early diagnosis of cerebral fat embolism syndrome by diffusion-weighted MRI (starfield pattern).

    abstract:BACKGROUND:Cerebral fat embolism syndrome is a rare, but potentially lethal, complication of long bone fractures. Neurological symptoms are variable, and the clinical diagnosis is difficult. The purpose of this case study is to demonstrate the value of diffusion-weighted MRI of the brain for early diagnosis of fat embo...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:

    authors: Parizel PM,Demey HE,Veeckmans G,Verstreken F,Cras P,Jorens PG,De Schepper AM

    更新日期:2001-12-01 00:00:00

  • Baseline Predictors of Poor Outcome in Patients Too Good to Treat With Intravenous Thrombolysis.

    abstract:BACKGROUND AND PURPOSE:Several studies have reported poor outcomes in patients too good to treat with intravenous thrombolysis because of mild or rapidly improving symptoms. We sought to determine baseline clinical and imaging predictors of poor outcome in these patients. METHODS:Among 3950 consecutive stroke admissio...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.116.014871

    authors: Ali SF,Siddiqui K,Ay H,Silverman S,Singhal A,Viswanathan A,Rost N,Lev M,Schwamm LH

    更新日期:2016-12-01 00:00:00

  • Establishment of government-initiated comprehensive stroke centers for acute ischemic stroke management in South Korea.

    abstract:BACKGROUND AND PURPOSE:In 2008, the Ministry of Health and Welfare of South Korea initiated the Regional Comprehensive Stroke Center (CSC) program to decrease the incidence and mortality of stroke nationwide. We evaluated the performance of acute ischemic stroke management after the Regional CSC program was introduced....

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.114.006134

    authors: Kim J,Hwang YH,Kim JT,Choi NC,Kang SY,Cha JK,Ha YS,Shin DI,Kim S,Lim BH

    更新日期:2014-08-01 00:00:00

  • Door-to-Needle Delays in Minor Stroke: A Causal Inference Approach.

    abstract:BACKGROUND AND PURPOSE:Thrombolysis rates among minor stroke (MS) patients are increasing because of increased recognition of disability in this group and guideline changes regarding treatment indications. We examined the association of delays in door-to-needle (DTN) time with stroke severity. METHODS:We performed a r...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.117.017386

    authors: Rostanski SK,Shahn Z,Elkind MSV,Liberman AL,Marshall RS,Stillman JI,Williams O,Willey JZ

    更新日期:2017-07-01 00:00:00

  • A proposed method for using a reimbursement moratorium to encourage recruitment for a randomized study of carotid endarterectomy.

    abstract::As indicated by Barnett, Plum and Walton, a definitive clinical trial to resolve the issue of the effectiveness of carotid endarterectomy is clearly needed. A proposal to foster such a trial, through a moratorium on third-party reimbursement other than for randomized patients, has herein been presented. ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.17.6.1335

    authors: Jonas S

    更新日期:1986-11-01 00:00:00

  • Regional cerebral blood flow, clinical manifestations, and age in children with moyamoya disease.

    abstract::In children with Moyamoya disease, transient ischemic attacks often occur during hyperventilation, and the frequency of attacks usually decreases with advancing age. To elucidate the mechanism of the attacks, the regional cerebral blood flow was measured during rest and/or hyperventilation in children aged 3-16 with M...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.18.5.906

    authors: Tagawa T,Naritomi H,Mimaki T,Yabuuchi H,Sawada T

    更新日期:1987-09-01 00:00:00

  • Ionic concomitants of astroglial transformation to reactive species.

    abstract::Brain injury, including ischemia, changes normal astrocytes into reactive species that hypertrophy and begin to proliferate. Understanding the mechanisms that underlie these changes could lead to new abilities to promote regeneration and retard neural degeneration after ischemia. Because ionic changes occur after nonn...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:

    authors: Kraig RP,Jaeger CB

    更新日期:1990-11-01 00:00:00

  • Diagnostic impact of cerebral transit time in the identification of microangiopathy in dementia: A transcranial ultrasound study.

    abstract:BACKGROUND AND PURPOSE:The diagnosis and quantification of microangiopathy in dementia is difficult. The assessment of small-vessel disease requires expensive and sophisticated nuclear medicine techniques. This study was performed to identify microangiopathy related to the integrity of cerebral microcirculation by sono...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.30.11.2291

    authors: Puls I,Hauck K,Demuth K,Horowski A,Schliesser M,Dörfler P,Scheel P,Toyka KV,Reiners K,Schöning M,Becker G

    更新日期:1999-11-01 00:00:00

  • Key role of CD36 in Toll-like receptor 2 signaling in cerebral ischemia.

    abstract:BACKGROUND AND PURPOSE:Toll-like receptors (TLRs) and the scavenger receptor CD36 are key molecular sensors for the innate immune response to invading pathogens. However, these receptors may also recognize endogenous "danger signals" generated during brain injury, such as cerebral ischemia, and trigger a maladaptive in...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.109.572552

    authors: Abe T,Shimamura M,Jackman K,Kurinami H,Anrather J,Zhou P,Iadecola C

    更新日期:2010-05-01 00:00:00

  • Prediction of reflex sympathetic dystrophy in hemiplegic patients by electromyographic study.

    abstract:BACKGROUND AND PURPOSE:This study was designed to investigate the correlation between reflex sympathetic dystrophy syndrome (RSDS) in hemiplegic patients and spontaneous electromyographic (EMG) activity, as well as to determine the predictive value of spontaneous EMG activity in early diagnosis of RSDS. METHODS:An EMG...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:

    authors: Cheng PT,Hong CZ

    更新日期:1995-12-01 00:00:00

  • Carotid plaque MRI and stroke risk: a systematic review and meta-analysis.

    abstract:BACKGROUND AND PURPOSE:MRI characterization of carotid plaque has been studied recently as a potential tool to predict stroke caused by carotid atherosclerosis. We performed a systematic review and meta-analysis to summarize the association of MRI-determined intraplaque hemorrhage, lipid-rich necrotic core, and thinnin...

    journal_title:Stroke

    pub_type: 杂志文章,meta分析,评审

    doi:10.1161/STROKEAHA.113.002551

    authors: Gupta A,Baradaran H,Schweitzer AD,Kamel H,Pandya A,Delgado D,Dunning A,Mushlin AI,Sanelli PC

    更新日期:2013-11-01 00:00:00

  • Effects of fosinopril and pravastatin on carotid intima-media thickness in subjects with increased albuminuria.

    abstract:BACKGROUND AND PURPOSE:Elevated urinary albumin excretion (UAE) is associated with an increased carotid intima-media thickness (IMT). Because angiotensin-converting enzyme inhibitors as well as statins have been shown to lower UAE and the progression of IMT, we assessed the effects of fosinopril and pravastatin on caro...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1161/01.STR.0000155731.92786.e9

    authors: Asselbergs FW,van Roon AM,Hillege HL,de Jong PE,Gans RO,Smit AJ,van Gilst WH,PREVEND IT Investigators.

    更新日期:2005-03-01 00:00:00

  • Better Collaterals Are Independently Associated With Post-Thrombolysis Recanalization Before Thrombectomy.

    abstract::Background and Purpose- In acute stroke patients with large vessel occlusion, the goal of intravenous thrombolysis (IVT) is to achieve early recanalization (ER). Apart from occlusion site and thrombus length, predictors of early post-IVT recanalization are poorly known. Better collaterals might also facilitate ER, for...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.118.022815

    authors: Seners P,Roca P,Legrand L,Turc G,Cottier JP,Cho TH,Arquizan C,Bracard S,Ozsancak C,Ben Hassen W,Naggara O,Lion S,Debiais S,Berthezene Y,Costalat V,Richard S,Magni C,Mas JL,Baron JC,Oppenheim C

    更新日期:2019-04-01 00:00:00

  • Higher Pulsatility in Cerebral Perforating Arteries in Patients With Small Vessel Disease Related Stroke, a 7T MRI Study.

    abstract::Background and Purpose- Cerebral small vessel disease (SVD) is a major cause of stroke and dementia, but underlying disease mechanisms are still largely unknown, partly because of the difficulty in assessing small vessel function in vivo. We developed a method to measure blood flow velocity pulsatility in perforating ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.118.022516

    authors: Geurts LJ,Zwanenburg JJM,Klijn CJM,Luijten PR,Biessels GJ

    更新日期:2018-12-11 00:00:00