Abstract:
:CSF hypocretin-1 levels at 6 PM did not significantly differ between patients with restless legs syndrome (RLS) and control subjects as measured by direct radioimmunoassay and after acid extraction. The authors did not observe significant differences between early onset and late onset RLS. Hypocretin-1 levels did not correlate with RLS severity or polysomnographic measures. These results contrast with previous findings reporting significantly increased CSF hypocretin-1 in the late evening and mostly in early onset RLS.
journal_name
Neurologyjournal_title
Neurologyauthors
Stiasny-Kolster K,Mignot E,Ling L,Möller JC,Cassel W,Oertel WHdoi
10.1212/01.wnl.0000094196.50155.38subject
Has Abstractpub_date
2003-11-25 00:00:00pages
1426-9issue
10eissn
0028-3878issn
1526-632Xjournal_volume
61pub_type
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