Progressive supranuclear palsy: loss of choline-acetyltransferase-like immunoreactive neurons in the pontine reticular formation.

abstract：:A patient with a large acoustic neuroma had contralateral hemifacial spasm. On CT, the brainstem was markedly displaced and distorted by the tumor. After total removal of the tumor the hemifacial spasm was temporarily worse, but disappeared 14 days after the operation. ...

journal_title：Neurology

authors： Nishi T,Matsukado Y,Nagahiro S,Fukushima M,Koga K

更新日期：1987-02-01 00:00:00

abstract：:Sensorimotor polyneuropathy developed in two workers who had been exposed to ethylene oxide gas repeatedly for several months. Sural nerve biopsies revealed axonal degeneration with mild changes of the myelin sheath. Unmyelinated fibers were also involved. Muscle biopsies showed typical denervation atrophy. Symptoms i...

journal_title：Neurology

authors： Kuzuhara S,Kanazawa I,Nakanishi T,Egashira T

更新日期：1983-03-01 00:00:00

abstract：:A 27-year-old man, recent visitor to the Middle East, presented with 6-week history of fever (up to 102°F) followed by altered behavior and left hemiparesis. CSF was acellular with raised protein (138 mg/dL). CSF bacterial culture was sterile; adenosine deaminase normal (3 U/L); cryptococcal antigen, Venereal Disease ...

journal_title：Neurology

authors： Rajan R,Khurana D,Kesav P

更新日期：2013-01-15 00:00:00

abstract：:We assayed serum folate levels of 60 patients with chronic fatigue syndrome (CFS) and found that 50% had values below 3.0 micrograms/l. Some patients with CFS are deficient in folic acid. ...

journal_title：Neurology

authors： Jacobson W,Saich T,Borysiewicz LK,Behan WM,Behan PO,Wreghitt TG

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Resistance to insulin-mediated glucose uptake by peripheral tissues is a cardinal defect in type 2 diabetes mellitus. Insulin resistance is also common among nondiabetic individuals, and may be an important risk factor for stroke in both populations. The authors review the definition, epidemiolog...

journal_title：Neurology

authors： Kernan WN,Inzucchi SE,Viscoli CM,Brass LM,Bravata DM,Horwitz RI

更新日期：2002-09-24 00:00:00

abstract：:The majority of patients with traumatic brain injury (TBI) are classified as having a mild TBI. Despite being categorized as mild, these individuals report ongoing and complex symptoms, which negatively affect their ability to complete activities of daily living and overall quality of life. Some of the major symptoms ...

journal_title：Neurology

authors： Elenberger J,Kim B,de Castro-Abeger A,Rex TS

更新日期：2020-11-03 00:00:00

abstract：:The Israeli Teratogen Information Service prospectively followed up 210 pregnancies with first trimester carbamazepine exposure. Pregnancy outcome was compared with that of two overlapping controls, matched and general (n = 629), exposed to nonteratogenic agents. Our study suggests a twofold increase in the rate of ma...

journal_title：Neurology

authors： Diav-Citrin O,Shechtman S,Arnon J,Ornoy A

更新日期：2001-07-24 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of opicapone as add-on to levodopa and the effects of switching from entacapone over 1 year of treatment in patients with fluctuating Parkinson disease. METHODS:After completion of a placebo- and entacapone-controlled double-blind study of opicapone (5, 25, or 50 mg), 495 patien...

journal_title：Neurology

authors： Ferreira JJ,Lees AJ,Poewe W,Rascol O,Rocha JF,Keller B,Soares-da-Silva P

更新日期：2018-05-22 00:00:00

abstract：:Reflex sympathetic dystrophy (RSD) is a relatively common disabling disorder of unknown pathophysiology. From a cohort of 52 patients, carefully selected to fulfill the recently formulated diagnostic criteria for RSD, venous blood samples were taken for typing of class I and II major histocompatibility antigens. The f...

journal_title：Neurology

authors： Kemler MA,van de Vusse AC,van den Berg-Loonen EM,Barendse GA,van Kleef M,Weber WE

更新日期：1999-10-12 00:00:00

abstract：:GM1 gangliosidosis is usually a pediatric disease caused by hereditary acid beta-galactosidase deficiency. There have been a few cases in adults. We saw a 51-year-old Japanese man with type 3 GM1 gangliosidosis who was manifesting dementia, dysarthria, gait disturbance, and limb rigidity. Radiologic studies showed pla...

journal_title：Neurology

authors： Ohta K,Tsuji S,Mizuno Y,Atsumi T,Yahagi T,Miyatake T

更新日期：1985-10-01 00:00:00

abstract：:We performed magnetic resonance imaging (MRI), before and after the administration of gadolinium-DTPA (Gd-DTPA), in 23 patients with medically refractory partial epilepsy who subsequently had surgical treatment for their seizure disorder. In most patients, 61%, unenhanced and enhanced MRI studies were negative. In 26%...

journal_title：Neurology

authors： Cascino GD,Hirschorn KA,Jack CR,Sharbrough FW

更新日期：1989-08-01 00:00:00

abstract：OBJECTIVE:To investigate the association of PD with preceding head trauma using a case-control study design. METHODS:The medical records-linkage system of the Rochester Epidemiology Project was used to identify 196 subjects who developed PD in Olmsted County, MN, from 1976 through 1995. Each incident case was matched ...

journal_title：Neurology

authors： Bower JH,Maraganore DM,Peterson BJ,McDonnell SK,Ahlskog JE,Rocca WA

更新日期：2003-05-27 00:00:00

abstract：OBJECTIVE:To describe four patients with temporal lobe epilepsy with limbic encephalitis unrelated to neoplasm. METHODS:The authors performed a retrospective evaluation of patient data obtained during presurgical evaluation, with additional CSF analyses, serum analyses, and histopathologic investigations. RESULTS:The...

journal_title：Neurology

authors： Bien CG,Schulze-Bonhage A,Deckert M,Urbach H,Helmstaedter C,Grunwald T,Schaller C,Elger CE

更新日期：2000-12-26 00:00:00

abstract：:A 52-year-old steelworker displayed a consistent defect in leftward voluntary gaze across the midline. Both fast (saccadic) and slow (pursuit) eye movements were affected. Neuro-ophthalmologic evaluation revealed no additional neurologic or ophthalmologic deficit. Pupilary miosis occurred during leftward gaze attempt,...

journal_title：Neurology

authors： Troost BT,Troost EG

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVE:Utilization of postacute care is associated with improved poststroke outcomes. However, more than 20% of American adults under age 65 are uninsured. We sought to determine whether insurance status is associated with utilization and intensity of institutional postacute care among working age stroke survivors. ...

journal_title：Neurology

authors： Skolarus LE,Meurer WJ,Burke JF,Prvu Bettger J,Lisabeth LD

更新日期：2012-05-15 00:00:00

abstract：:Many patients with epilepsy can be successfully treated with a single antiepileptic drug (monotherapy). However, in a substantial number of patients, monotherapy does not provide satisfactory seizure control, and the use of two or more drugs, or polypharmacy, is required. Selection of rational combination therapy requ...

journal_title：Neurology

authors： Ferrendelli JA

更新日期：1995-03-01 00:00:00

abstract：OBJECTIVE:To study the long-term dual inhibitory effects of rivastigmine on acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) in patients with AD. METHODS:Eleven patients with mild AD received rivastigmine for 12 months. Cholinesterase (ChE) activities in the CSF and plasma were assessed colorimetrically. ...

journal_title：Neurology

authors： Darreh-Shori T,Almkvist O,Guan ZZ,Garlind A,Strandberg B,Svensson AL,Soreq H,Hellström-Lindahl E,Nordberg A

更新日期：2002-08-27 00:00:00

abstract：:Subacute sclerosing panencephalitis (SSPE) is characterized by a hyperimmune state toward the polypeptides of measles virus except the matrix (M) protein. Using cloned (3H)-labeled complementary DNA probes for in situ hybridization, we found the M protein and nucleocapsid (NP) protein nucleotide sequences in glial cel...

journal_title：Neurology

authors： Shapshak P,Tourtellotte WW,Nakamura S,Graves MC,Darvish M,Hoffman D,Walsh MJ,Fareed GC,Schmid P,Heinzmann C

更新日期：1985-11-01 00:00:00

abstract：:The authors investigated whether the lack of effect of tirilazad on clinical outcome in patients with acute ischemic stroke is explained by failure of tirilazad to reduce infarct volume. Overall, tirilazad had no significant effect on infarct volume. In the subgroups of male patients and of those with a cortical infar...

journal_title：Neurology

authors： van der Worp HB,Kappelle LJ,Algra A,Bär PR,Orgogozo JM,Ringelstein EB,Bath PM,van Gijn J,TESS Investigators.,TESS II Investigators.

更新日期：2002-01-08 00:00:00

abstract：:Five men with degenerative neuromuscular diseases (three with amyotrophic lateral sclerosis [ALS] and two with Duchenne's muscular dystrophy [DMD]) who had respiratory failure were treated with intermittent negative pressure ventilation (NPV). One patient with ALS in severe acute respiratory failure was successfully t...

journal_title：Neurology

authors： Braun SR,Sufit RL,Giovannoni R,O'Connor M,Peters H

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND:Idiopathic adult-onset primary dystonia usually affects the upper body and remains focal. Underlying mechanisms are unknown, and there are only limited neuropathologic studies in the literature. Recently, ubiquitinated perinuclear inclusion bodies were found in the brainstem of patients with DYT1-related dys...

journal_title：Neurology

authors： Holton JL,Schneider SA,Ganesharajah T,Gandhi S,Strand C,Shashidharan P,Barreto J,Wood NW,Lees AJ,Bhatia KP,Revesz T

更新日期：2008-02-26 00:00:00

abstract：OBJECTIVE:To determine if progressive brain atrophy could be detected over 1- and 2-year intervals in relapsing MS, based on annual MR studies from the Multiple Sclerosis Collaborative Research Group (MSCRG) trial of interferon beta-1a (Avonex). METHODS:All subjects had mild to moderate disability, with baseline expan...

journal_title：Neurology

authors： Simon JH,Jacobs LD,Campion MK,Rudick RA,Cookfair DL,Herndon RM,Richert JR,Salazar AM,Fischer JS,Goodkin DE,Simonian N,Lajaunie M,Miller DE,Wende K,Martens-Davidson A,Kinkel RP,Munschauer FE 3rd,Brownscheidle CM

更新日期：1999-07-13 00:00:00

abstract：BACKGROUND:Several studies indicate semantic fluency more sensitively discriminates patients with Alzheimer disease (AD) from normal elderly persons, with disproportionate impairment of semantic over phonemic fluency. OBJECTIVE:To determine the ability of abbreviated fluency measures in the clinic setting (1-minute le...

journal_title：Neurology

authors： Canning SJ,Leach L,Stuss D,Ngo L,Black SE

更新日期：2004-02-24 00:00:00

abstract：:The authors report an autosomal dominant episodic ataxia that is clinically distinct from the other episodic ataxias. Vestibular ataxia, vertigo, tinnitus, and interictal myokymia are prominent; attacks are diminished by acetazolamide. Linkage analyses of markers flanking the EA1 and EA2 loci demonstrate genetic exclu...

journal_title：Neurology

authors： Steckley JL,Ebers GC,Cader MZ,McLachlan RS

更新日期：2001-10-23 00:00:00

abstract：:Many studies have demonstrated that dipyridamole is not purely an antiplatelet agent but also exerts its antithrombotic properties through the vessel wall. Using a laboratory model in which bovine endothelial cells are seeded to form a subendothelial matrix (SEM), investigators have shown that dipyridamole enhances th...

journal_title：Neurology

authors： Eisert WG

更新日期：2001-01-01 00:00:00

abstract：:We have performed positron emission tomography (PET) with 2-deoxy-2[18F]fluoro-D-glucose (FDG) in eight infants and children (aged 18 days to 5 years) with medically refractory epilepsy of neonatal onset. It was hypothesized that in at least some of these infants a surgical approach (focal resection, cerebral hemisphe...

journal_title：Neurology

authors： Chugani HT,Shewmon DA,Peacock WJ,Shields WD,Mazziotta JC,Phelps ME

更新日期：1988-08-01 00:00:00

abstract：OBJECTIVE:To describe neural autoantibody profiles and outcomes in patients with neurologic autoimmunity associated with immune checkpoint inhibitor (ICI) cancer immunotherapy. METHODS:In this retrospective descriptive study, 63 patients with ICI-related neurologic autoimmunity were included: 39 seen at the Mayo Clini...

journal_title：Neurology

authors： Sechi E,Markovic SN,McKeon A,Dubey D,Liewluck T,Lennon VA,Lopez-Chiriboga AS,Klein CJ,Mauermann M,Pittock SJ,Flanagan EP,Zekeridou A

更新日期：2020-10-27 00:00:00

abstract：:A collector is a person who collects things on purpose, either as a hobby or business, or for personal satisfaction, e.g., stamp, coin, or art collector. In such instances, the act of collecting things represents voluntary, controlled, goal-directed, selective searching. Pathologic patterns of collecting have been obs...

journal_title：Neurology

authors： Volle E,Beato R,Levy R,Dubois B

更新日期：2002-02-12 00:00:00

abstract：:The authors evaluated response, time to progression (TTP), survival, prognostic factors, and toxicity in 63 patients with a recurrent glioblastoma multiforme treated with procarbazine, lomustine, and vincristine (PCV) chemotherapy. Complete and partial response was observed in two (3%) and five patients (8%). In 16 pa...

journal_title：Neurology

authors： Kappelle AC,Postma TJ,Taphoorn MJ,Groeneveld GJ,van den Bent MJ,van Groeningen CJ,Zonnenberg BA,Sneeuw KC,Heimans JJ

更新日期：2001-01-09 00:00:00

abstract：BACKGROUND:Bilateral absent N20 responses of median nerve somatosensory evoked potentials (SEPs) reliably predict poor prognosis after cardiac arrest. However, the studies supporting this fact were carried out before hypothermia was established as standard treatment. Recent evidence suggests that hypothermia treatment ...

journal_title：Neurology

authors： Leithner C,Ploner CJ,Hasper D,Storm C

更新日期：2010-03-23 00:00:00