Near-field amplification of antithrombotic effects of dipyridamole through vessel wall cells.

abstract：:Cerebral necrosis following stroke exposes brain antigens to the immune system, potentially initiating an antibody response. The authors measured levels of antibodies to specific neuronal antigens, neurofilaments (NF), and a ubiquitous antigen, cardiolipin (CL), in 45 patients following an acute first-ever stroke, wit...

journal_title：Neurology

authors： Bornstein NM,Aronovich B,Korczyn AD,Shavit S,Michaelson DM,Chapman J

更新日期：2001-02-27 00:00:00

abstract：BACKGROUND:The Vietnam Head Injury Study (VHIS) is a prospective, longitudinal follow-up of 1,221 Vietnam War veterans with mostly penetrating head injuries (PHIs). The high prevalence (45%-53%) of posttraumatic epilepsy (PTE) in this unique cohort makes it valuable for study. METHODS:A standardized multidisciplinary ...

journal_title：Neurology

authors： Raymont V,Salazar AM,Lipsky R,Goldman D,Tasick G,Grafman J

更新日期：2010-07-20 00:00:00

abstract：OBJECTIVE:Migrainous infarction is considered a rare complication of migraine. Although several studies reported silent brain lesions on neuroimaging in patients with migraine with aura, knowledge about lesion patterns in acute migrainous infarction is scarce. We investigated clinical and MRI characteristics in a serie...

journal_title：Neurology

authors： Wolf ME,Szabo K,Griebe M,Förster A,Gass A,Hennerici MG,Kern R

更新日期：2011-05-31 00:00:00

abstract：:Evidence suggests that untreated obstructive sleep apnea (OSA) can lead to hypertension, cardiovascular disease, and stroke. Conversely, the systemic effects of a wide variety of critical illnesses can lead to CNS dysfunction, which can precipitate respiratory failure. Reported is a patient in whom an acute encephalop...

journal_title：Neurology

authors： Dyken ME,Yamada T,Berger HA

更新日期：2003-05-27 00:00:00

abstract：BACKGROUND:Multiple system atrophy (MSA) is an atypical parkinsonian syndrome including cerebellar impairment and poor response to levodopa. We assessed right hand motor activation in patients with MSA before and after an acute levodopa challenge in comparison with patients with PD and healthy volunteers (HVs). METHOD...

journal_title：Neurology

authors： Payoux P,Brefel-Courbon C,Ory-Magne F,Regragui W,Thalamas C,Balduyck S,Durif F,Azulay JP,Tison F,Blin O,Esquerre JP,Rascol O

更新日期：2010-09-28 00:00:00

abstract：OBJECTIVE:To determine the incidence of multiple sclerosis (MS) in a longitudinal surveillance over 35 years and to estimate the prevalence rate in Saskatoon, Saskatchewan, on January 1, 2005. METHODS:A population-based registry was established in 1969, and identification of cases continued to 2005, from medical recor...

journal_title：Neurology

authors： Hader WJ,Yee IM

更新日期：2007-09-18 00:00:00

abstract：:Adult-onset dystonia-parkinsonism is a syndrome in search of a pathology. We therefore reviewed the literature on dystonic manifestations in autopsy-proven cases of multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and idiopathic Parkinson's disease (PD). Only 6 of 140 autopsy reports of MSA remarke...

journal_title：Neurology

authors： Rivest J,Quinn N,Marsden CD

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVE:To characterize disease severity and distribution of disability in pediatric-onset multiple sclerosis (POMS) and to develop an optimized modeling scale for measuring disability, we performed a multicenter retrospective analysis of disability scores in 873 persons with POMS over time and compared this to previ...

journal_title：Neurology

authors： Santoro JD,Waltz M,Aaen G,Belman A,Benson L,Gorman M,Goyal MS,Graves JS,Harris Y,Krupp L,Lotze T,Mar S,Moodley M,Ness J,Rensel M,Rodriguez M,Schreiner T,Tillema JM,Waubant E,Weinstock-Guttman B,Hurtubise BF,Roal

更新日期：2020-09-29 00:00:00

abstract：:Two patients with acute onset of profound weakness and loss of muscle bulk during a critical illness had unusual histopathological changes of type II myofibers. Both patients had respiratory failure and prolonged neuromuscular blockade. High-dose steroids were used in only one case and atracurium in the other. Muscle ...

journal_title：Neurology

authors： Gutmann L,Blumenthal D,Gutmann L,Schochet SS

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVE:To determine whether cardiac magnetic resonance imaging (CMR) could be useful in identifying previously undiagnosed cardiomyopathies in a cohort of patients with ischemic stroke who underwent standard etiologic investigation and to describe the type and frequency of these cardiomyopathies. METHODS:We perform...

journal_title：Neurology

authors： Fonseca AC,Marto JP,Pimenta D,Guimarães T,Alves PN,Inácio N,Viana-Baptista M,Pinho E Melo T,Pinto FJ,Ferro JM,Almeida AG

更新日期：2020-01-07 00:00:00

abstract：OBJECTIVE:To evaluate the relationship of white matter hyperintensities (WMH) with decline in lower extremity function (LEF) over approximately 3 years in dementia-free older adults with memory complaints. METHODS:We obtained brain MRI data from 458 community-dwelling adults, aged 70 years or over, at baseline, and fr...

journal_title：Neurology

authors： Moon SY,de Souto Barreto P,Rolland Y,Chupin M,Bouyahia A,Fillon L,Mangin JF,Andrieu S,Cesari M,Vellas B,MAPT\/DSA Study Group.

更新日期：2018-04-10 00:00:00

abstract：:We studied brain sections from 10 patients with the acquired immunodeficiency syndrome (AIDS) and progressive multifocal leukoencephalopathy (PML) by in situ hybridization with a biotin-labeled JC virus (JCV) DNA probe and by immunohistochemistry using antibody against the JCV capsid antigen. We compared the results w...

journal_title：Neurology

authors： Aksamit AJ,Gendelman HE,Orenstein JM,Pezeshkpour GH

更新日期：1990-07-01 00:00:00

abstract：OBJECTIVE:To determine whether exposure to repetitive head impacts over a single season negatively affects cognitive performance in collegiate contact sport athletes. METHODS:This is a prospective cohort study at 3 Division I National Collegiate Athletic Association athletic programs. Participants were 214 Division I ...

journal_title：Neurology

authors： McAllister TW,Flashman LA,Maerlender A,Greenwald RM,Beckwith JG,Tosteson TD,Crisco JJ,Brolinson PG,Duma SM,Duhaime AC,Grove MR,Turco JH

更新日期：2012-05-29 00:00:00

abstract：OBJECTIVES:To study the behavioral and neuroanatomic characteristics of perseverative behavior encountered on a target cancellation task in patients with neglect. METHODS:Motor perseverative behavior during line cancellation task was evaluated retrospectively in 60 patients with left hemispatial neglect from right hem...

journal_title：Neurology

authors： Na DL,Adair JC,Kang Y,Chung CS,Lee KH,Heilman KM

更新日期：1999-05-12 00:00:00

abstract：:Recent clinical neuropathologic reports are inconsistent with previous models of how pontine neural circuits generate saccadic eye movements. We present a hypothetical explanation of these and other clinical and experimental findings based on a new model that accurately predicts the eye signs in pontine lesions. ...

journal_title：Neurology

authors： Kaneko CR

更新日期：1989-07-01 00:00:00

abstract：:The triad of normal-pressure hydrocephalus, parkinsonism, and primary empty sella appeared in a 70-year-old woman. There was dramatic resolution of the extrapyramidal signs and symptoms on treatment with levodopa-carbidopa and ventriculojugular shunt. The syndrome may be the result of several mechanisms, but an altera...

journal_title：Neurology

authors： Spagna VA,Maeder MC,Johnson JC,Mazzaferri EL

更新日期：1978-11-01 00:00:00

abstract：:Neurologic disorders are among the most frequent causes of morbidity and mortality in the United States. Moreover, the current shortfall of neurologists is expected to worsen over the coming decade. As a consequence, many patients with neurologic disorders will be treated by physicians and primary care providers witho...

journal_title：Neurology

authors： Sandrone S,Berthaud JV,Chuquilin M,Cios J,Ghosh P,Gottlieb-Smith RJ,Kushlaf H,Mantri S,Masangkay N,Menkes DL,Nevel KS,Sarva H,Schneider LD

更新日期：2019-01-22 00:00:00

abstract：OBJECTIVE:To investigate the involvement of the epidermal small sensory fibers in the neurodegenerative process in amyotrophic lateral sclerosis (ALS). METHODS:In the present study, skin biopsies of 28 patients with ALS were obtained at an average of 34 months after disease onset by history. Protein gene product 9.5 (...

journal_title：Neurology

authors： Weis J,Katona I,Müller-Newen G,Sommer C,Necula G,Hendrich C,Ludolph AC,Sperfeld AD

更新日期：2011-06-07 00:00:00

abstract：:We previously compared the diagnostic capabilities of MRI of the head with CT, evoked potentials, and CSF oligoclonal banding (OB) analysis in a prospective evaluation of 200 patients with suspected multiple sclerosis (MS). To examine the ability of MRI and other paraclinical tests to predict the diagnosis of clinical...

journal_title：Neurology

authors： Lee KH,Hashimoto SA,Hooge JP,Kastrukoff LF,Oger JJ,Li DK,Paty DW

更新日期：1991-05-01 00:00:00

abstract：OBJECTIVES:This study aims to investigate if patients with inflammatory neuropathies and tremor have evidence of dysfunction in the cerebellum and interactions in sensorimotor cortex compared to nontremulous patients and healthy controls. METHODS:A prospective data collection study investigating patients with inflamma...

journal_title：Neurology

authors： Schwingenschuh P,Saifee TA,Katschnig-Winter P,Reilly MM,Lunn MP,Manji H,Aguirregomozcorta M,Schmidt R,Bhatia KP,Rothwell JC,Edwards MJ

更新日期：2013-05-14 00:00:00

abstract：OBJECTIVE:Diagnostic criteria from 2002 classify transverse myelitis (TM) as idiopathic or disease associated but predate the discovery of aquaporin-4 (AQP4)-immunoglobulin G (IgG) and myelin oligodendrocyte glycoprotein (MOG)-IgG, which associate with TM. Prior incidence estimates of idiopathic TM (ITM) range from 1 t...

journal_title：Neurology

authors： Sechi E,Shosha E,Williams JP,Pittock SJ,Weinshenker BG,Keegan BM,Zalewski NL,Lopez-Chiriboga AS,Jitprapaikulsan J,Flanagan EP

更新日期：2019-07-23 00:00:00

abstract：BACKGROUND:Elevated serum retinol, CSF retinol, and serum retinol binding protein (RBP) levels have been found in some patients with idiopathic intracranial hypertension (IIH), but serum and CSF retinol levels have not been studied in matched serum and CSF samples in patients with IIH. OBJECTIVE:To determine whether s...

journal_title：Neurology

authors： Tabassi A,Salmasi AH,Jalali M

更新日期：2005-06-14 00:00:00

abstract：OBJECTIVE:To describe the clinical features, MRI findings, and pathogenesis of strokes producing internuclear ophthalmoplegia (INO) as an isolated or predominant clinical manifestation. METHODS:Thirty patients presenting with INO without (n = 12) or with (n = 18) minimal other neurologic signs were studied. MRI and an...

journal_title：Neurology

authors： Kim JS

更新日期：2004-05-11 00:00:00

abstract：:Although the ultimate diagnosis of multiple sclerosis (MS) still remains clinical, confirmatory laboratory aids can be of marked assistance, especially in early and atypical cases. Whereas numerous tests have been described, the only ones to withstand scrutiny in numerous laboratories have been various immunoglobulin ...

journal_title：Neurology

authors： Johnson KP

更新日期：1980-07-01 00:00:00

abstract：OBJECTIVE:To study the attributes of quantitative strength testing using hand-held dynamometry (HHD) as an efficacy measure in 2 large phase 3 amyotrophic lateral sclerosis (ALS) trials. METHODS:In the phase 3 trials of ceftriaxone and dexpramipexole, 513 and 943 patients, respectively, were enrolled in double-blind, ...

journal_title：Neurology

authors： Shefner JM,Liu D,Leitner ML,Schoenfeld D,Johns DR,Ferguson T,Cudkowicz M

更新日期：2016-08-09 00:00:00

abstract：:The progressive myoclonus epilepsies (PMEs) are a devastating group of rare disorders(1) that manifest with increasing action myoclonus, which is also present at rest but activates with stimuli such as noise, light, or touch. Ultimately, patients become wheelchair-bound and experience early death. Neurologic signs tha...

journal_title：Neurology

authors： Knupp K,Wirrell E

更新日期：2014-02-04 00:00:00

abstract：:Regional levels of brain monoamines and their metabolites were examined in a rat model of reversible and diffuse forebrain ischemia with and without reperfusion. During ischemia, blood flow decreased by 87 to 95%, but recovered to control values during recirculation. Norepinephrine and serotonin decreased in the cereb...

journal_title：Neurology

authors： Harik SI,Yoshida S,Busto R,Ginsberg MD

更新日期：1986-07-01 00:00:00

abstract：:Patients, clinicians, and hospitals have undergone monumental changes during the coronavirus disease 2019 (COVID-19) pandemic. This crisis has forced us to consider the obligations that we neurologists have to our individual patients as well as the greater community. By returning to our fundamental understanding of th...

journal_title：Neurology

authors： Rubin MA,Bonnie RJ,Epstein L,Hemphill C,Kirschen M,Lewis A,Suarez JI,Ethics, Law, and Humanities Committee, a joint committee of the American Academy of Neurology, American Neurological Association, and Child Neurology Society; in collabor

更新日期：2020-07-28 00:00:00

abstract：:Behavioral testing following division of the corpus callosum has shown that the anterior commissure can transfer information related to visual tasks interhemispherically in nonhuman primates but not in humans. We have found that the ratio of anterior commissure cross-sectional area to total neocortical commissural are...

journal_title：Neurology

authors： Foxman BT,Oppenheim J,Petito CK,Gazzaniga MS

更新日期：1986-11-01 00:00:00

abstract：OBJECTIVE:Based on the theories of brain reserve and cognitive reserve, we investigated whether larger maximal lifetime brain growth (MLBG) and/or greater lifetime intellectual enrichment protect against cognitive decline over time. METHODS:Forty patients with multiple sclerosis (MS) underwent baseline and 4.5-year fo...

journal_title：Neurology

authors： Sumowski JF,Rocca MA,Leavitt VM,Dackovic J,Mesaros S,Drulovic J,DeLuca J,Filippi M

更新日期：2014-05-20 00:00:00