Abstract:
:Cerebral necrosis following stroke exposes brain antigens to the immune system, potentially initiating an antibody response. The authors measured levels of antibodies to specific neuronal antigens, neurofilaments (NF), and a ubiquitous antigen, cardiolipin (CL), in 45 patients following an acute first-ever stroke, within 48 hours, and 1, 3, and 6 months later. The mean levels of anti-NF antibodies were elevated compared with baseline at 1, 3, and 6, months (p = 0.012, 0.002, and 0.003 by paired t-test). Anti-CL levels did not change significantly.
journal_name
Neurologyjournal_title
Neurologyauthors
Bornstein NM,Aronovich B,Korczyn AD,Shavit S,Michaelson DM,Chapman Jdoi
10.1212/wnl.56.4.529subject
Has Abstractpub_date
2001-02-27 00:00:00pages
529-30issue
4eissn
0028-3878issn
1526-632Xjournal_volume
56pub_type
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