Abstract:
:MRI and CSF investigations revealed meningeal involvement in a 29-year-old patient with biopsy-confirmed Wegener's granulomatosis. The intracranial manifestation of Wegener's granulomatosis was supported by the detection of pathologic circulating antineutrophil cytoplasm (c-ANCA) in the CSF. We monitored disease activity by c-ANCA measurement in the CSF. After repeated cycles of intrathecal administration of methotrexate and corticoids, progression of meningeal infiltration stopped, and CSF c-ANCA titers became negative.
journal_name
Neurologyjournal_title
Neurologyauthors
Spranger M,Schwab S,Meinck HM,Tischendorf M,Sis J,Breitbart A,Andrassy Kdoi
10.1212/wnl.48.1.263subject
Has Abstractpub_date
1997-01-01 00:00:00pages
263-5issue
1eissn
0028-3878issn
1526-632Xjournal_volume
48pub_type
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