Abstract:
OBJECTIVE:To compare nondemented patients with Parkinson's disease (PD) with and without REM sleep behavior disorder (RBD) to healthy controls on quantitative EEG characteristics for both wakefulness and REM sleep. METHODS:Fifteen patients with PD (7 patients with polysomnographic-confirmed RBD [PD-RBD] and 8 patients without RBD [PD-NRBD]) and 15 healthy control subjects were studied. Each subject underwent a quantitative EEG analysis of both wakefulness and REM sleep. RESULTS:During wakefulness, patients with PD-RBD showed a higher theta power in frontal, parietal, temporal, and occipital regions in comparison to patients with PD-NRBD and control subjects. Moreover, a slowing of the dominant occipital frequency was observed only in patients with PD-RBD (p < 0.02). Patients with PD-NRBD did not present any slowing of the EEG. No between-group difference in quantitative REM sleep EEG was observed. CONCLUSIONS:This study demonstrates that the EEG slowing reported during wakefulness in nondemented patients with PD is strongly related to the presence of RBD.
journal_name
Neurologyjournal_title
Neurologyauthors
Gagnon JF,Fantini ML,Bédard MA,Petit D,Carrier J,Rompré S,Décary A,Panisset M,Montplaisir Jdoi
10.1212/01.wnl.0000106460.34682.e9subject
Has Abstractpub_date
2004-02-10 00:00:00pages
401-6issue
3eissn
0028-3878issn
1526-632Xjournal_volume
62pub_type
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