Hepatitis C virus infection and neurocognitive function.

abstract：:Effective diagnosis and treatment of cytomegalovirus infection of the nervous system in AIDS patients has been limited by a lack of sensitive diagnostic measures. Retrospective series suggest a poor prognosis for cytomegalovirus encephalitis with rapid mortality. Polymerase chain reaction amplification of cytomegalovi...

journal_title：Neurology

authors： Cohen BA

更新日期：1996-02-01 00:00:00

abstract：:We followed 18 multiple sclerosis patients clinically and with repeated brain MRIs with and without gadolinium for over 1 year. Clinical evaluations included scoring on the Kurtzke Expanded Disability Status Scale (EDSS) and the Ambulation Index (AI) scale. There was a significant correlation between the change in EDS...

journal_title：Neurology

authors： Khoury SJ,Guttmann CR,Orav EJ,Hohol MJ,Ahn SS,Hsu L,Kikinis R,Mackin GA,Jolesz FA,Weiner HL

更新日期：1994-11-01 00:00:00

abstract：:The prevalence and psychopathologic features of psychiatric adverse events (PAE) in 517 patients taking levetiracetam (LEV) were investigated. Fifty-three (10.1%) patients developed PAE. A significant association was found with previous psychiatric history, history of febrile convulsions, and history of status epilept...

journal_title：Neurology

authors： Mula M,Trimble MR,Yuen A,Liu RS,Sander JW

更新日期：2003-09-09 00:00:00

abstract：:The authors evaluated education attainment and neuropsychological deficits in children with sickle cell disease (SCD) and silent cerebral infarcts. Children with silent infarcts had twice the rate of school difficulties as children without infarcts. Eighty percent of silent infarct cases had clinically significant cog...

journal_title：Neurology

authors： Schatz J,Brown RT,Pascual JM,Hsu L,DeBaun MR

更新日期：2001-04-24 00:00:00

abstract：OBJECTIVE:To assess the effect of patient and drug characteristics on medication adherence in people with epilepsy (PWE) in a large cohort representative of the German population. METHODS:Information was obtained from the Disease Analyzer database that collects anonymous demographic and medical data from practice comp...

journal_title：Neurology

authors： Gollwitzer S,Kostev K,Hagge M,Lang J,Graf W,Hamer HM

更新日期：2016-08-02 00:00:00

abstract：BACKGROUND:Hereditary neuralgic amyotrophy (HNA) is an autosomal-dominant disorder associated with recurrent, episodic, painful, brachial neuropathy. The gene for HNA has been mapped to chromosome 17q25. Characteristic features including hypotelorism, short stature, and cleft palate occur in some patients. OBJECTIVE:T...

journal_title：Neurology

authors： Jeannet PY,Watts GD,Bird TD,Chance PF

更新日期：2001-12-11 00:00:00

abstract：OBJECTIVE:Idiopathic REM sleep behavior disorder is a parasomnia characterized by dream enactment and is commonly a prediagnostic sign of parkinsonism and dementia. Since risk factors have not been defined, we initiated a multicenter case-control study to assess environmental and lifestyle risk factors for REM sleep be...

journal_title：Neurology

authors： Postuma RB,Montplaisir JY,Pelletier A,Dauvilliers Y,Oertel W,Iranzo A,Ferini-Strambi L,Arnulf I,Hogl B,Manni R,Miyamoto T,Mayer G,Stiasny-Kolster K,Puligheddu M,Ju Y,Jennum P,Sonka K,Santamaria J,Fantini ML,Zucconi

更新日期：2012-07-31 00:00:00

abstract：OBJECTIVES:To test the hypothesis that neuropsychiatric symptomatology is predictive of the success of seizure control in patients newly treated with antiepileptic drugs (AEDs), and that this predictive value adds to that provided by other clinical, imaging, and genomic factors in a multivariate model. METHODS:One hun...

journal_title：Neurology

authors： Petrovski S,Szoeke CE,Jones NC,Salzberg MR,Sheffield LJ,Huggins RM,O'Brien TJ

更新日期：2010-09-14 00:00:00

abstract：OBJECTIVE:To conduct a comprehensive analysis of circulating metabolites and incident stroke in large prospective population-based settings. METHODS:We investigated the association of metabolites with risk of stroke in seven prospective cohort studies including 1,791 incident stroke events among 38,797 participants in...

journal_title：Neurology

authors： Vojinovic D,Kalaoja M,Trompet S,Fischer K,Shipley MJ,Li S,Havulinna AS,Perola M,Salomaa V,Yang Q,Sattar N,Jousilahti P,Amin N,Satizabal CL,Taba N,Sabayan B,Vasan RS,Ikram MA,Stott DJ,Ala-Korpela M,Jukema JW,Sesh

更新日期：2020-12-02 00:00:00

abstract：:There is evidence that treatment with an antibody to tumor necrosis factor alpha (TNF alpha) improves an animal model of multiple sclerosis (MS) and is beneficial in two systemic inflammatory disease in humans, but there are no reports about anti-TNF treatment of MS. Therefore, we treated two rapidly progressive MS pa...

journal_title：Neurology

authors： van Oosten BW,Barkhof F,Truyen L,Boringa JB,Bertelsmann FW,von Blomberg BM,Woody JN,Hartung HP,Polman CH

更新日期：1996-12-01 00:00:00

abstract：:The role of gender in the pathogenesis of Alzheimer's disease (AD) is an important issue that remains controversial. We compared men and women in late-onset familial AD kindreds for the risk of developing AD by studying 26 well-characterized familial AD kindreds from the Oregon Alzheimer Disease Center and, for confir...

journal_title：Neurology

authors： Payami H,Montee K,Grimslid H,Shattuc S,Kaye J

更新日期：1996-01-01 00:00:00

abstract：:The question of the appropriate use of opiate analgesics in the management of chronic headache pain is under debate. Often, the management of headache pain is complicated by the overuse of dependency-promoting analgesics. Because of confusion about the use of analgesics in pain management, some patients are denied acc...

journal_title：Neurology

authors： Markley HG

更新日期：1994-05-01 00:00:00

abstract：:Successful screening for neuropathy in patients with diabetes is available using the 10 g Semmes-Weinstein monofilament (Mid-Delta Health Systems, Inc., Belzoni, MS) (touch/pressure sensation) and the Neurothesiometer (Horwell Scientific, London, UK; vibration perception threshold). In healthy volunteers and patients ...

journal_title：Neurology

authors： Dimitrakoudis D,Bril V

更新日期：2002-08-27 00:00:00

abstract：:Using PET with the opioidergic ligand [11C]diprenorphine, the authors demonstrate decreased tracer binding in the pineal gland of cluster headache patients vs healthy volunteers. Opioid receptor availability in the hypothalamus and cingulate cortex depended on the duration of the headache disorder. Therefore, the path...

journal_title：Neurology

authors： Sprenger T,Willoch F,Miederer M,Schindler F,Valet M,Berthele A,Spilker ME,Förderreuther S,Straube A,Stangier I,Wester HJ,Tölle TR

更新日期：2006-04-11 00:00:00

abstract：:In the aftermath of an acute cardiovascular event such as stroke, patients and families frequently ask whether preceding circumstances such as viral illnesses, stress, and other medical or surgical events brought on the disease. Although it seems intuitive to patients and families that acute precipitants or disease tr...

journal_title：Neurology

authors： Jeerakathil T,Lo W

更新日期：2014-03-18 00:00:00

abstract：OBJECTIVE:To investigate whether quantitative MR techniques can be used to distinguish between mesial temporal sclerosis in patients with a history of prolonged febrile convulsion and in patients without such a history. METHODS:Quantitative hippocampal T2 relaxometry, hippocampal volumetry, and single voxel (1)H-MRS d...

journal_title：Neurology

authors： Scott RC,Gadian DG,Cross JH,Wood SJ,Neville BG,Connelly A

更新日期：2001-06-26 00:00:00

abstract：BACKGROUND:In polyneuropathy associated with immunoglobulin M (IgM) monoclonal gammopathy, antibodies to myelin-associated glycoprotein (MAG), sulfoglucuronyl paragloboside (SGPG), and sulfatide have been associated with specific clinical and electrophysiologic features. However, it is not known whether the results of ...

journal_title：Neurology

authors： Eurelings M,Moons KG,Notermans NC,Sasker LD,De Jager AE,Wintzen AR,Wokke JH,Van den Berg LH

更新日期：2001-01-23 00:00:00

abstract：OBJECTIVE:To quantify the isoprostane 8,12-iso-iPF2alpha-VI in brain tissues obtained from patients with AD, patients with frontotemporal dementia (FTD), and controls. BACKGROUND:Enhanced brain oxidative stress with secondary damage to cellular macromolecules may play a role in the pathogenesis of AD and FTD. The isop...

journal_title：Neurology

authors： Yao Y,Zhukareva V,Sung S,Clark CM,Rokach J,Lee VM,Trojanowski JQ,Praticò D

更新日期：2003-08-26 00:00:00

abstract：:Restless legs syndrome (RLS) is characterized by an urge to move the legs. The symptoms are more intense in the evening and during periods of inactivity. RLS symptoms are relieved by movement. It is classified as a sleep disorder, but in many ways it is actually a disorder of wakefulness that seems to intrude upon the...

journal_title：Neurology

authors： Auerbach S,Walters AS

更新日期：2014-04-08 00:00:00

abstract：:Nuclear magnetic resonance (NMR) imaging was superior to CT for imaging the brain lesions of 27 patients with MS. The incidence of abnormal examinations was 78% by NMR and 63% by CT. In cases in which both studies were abnormal, NMR usually demonstrated many more lesions and more extensive involvement than CT. The app...

journal_title：Neurology

authors： Jacobs L,Kinkel WR,Polachini I,Kinkel RP

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:To compare characteristics between Black and White patients with amyotrophic lateral sclerosis (ALS) in order to identify disparities and phenotypic variability. METHODS:We performed database review for patients seen between 1997 and 2020 at the Emory ALS Center in Atlanta, Georgia. Patients with ALS were in...

journal_title：Neurology

authors： Brand D,Polak M,Glass JD,Fournier CN

更新日期：2020-12-28 00:00:00

abstract：:Early motor manifestations are the main components of focal seizures involving the frontal lobe. We examined the relationship between the initial ictal motor manifestations and interictal abnormalities of cerebral glucose consumption (rCMRGlc) as assessed by PET in 48 consecutive patients with focal seizures of neocor...

journal_title：Neurology

authors： Schlaug G,Antke C,Holthausen H,Arnold S,Ebner A,Tuxhorn I,Jäncke L,Lüders H,Witte OW,Seitz RJ

更新日期：1997-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the predictive utility of self-reported and informant-reported functional deficits in patients with mild cognitive impairment (MCI) for the follow-up diagnosis of probable AD. METHODS:The Pfeffer Functional Activities Questionnaire (FAQ) and Lawton Instrumental Activities of Daily Living (IADL) S...

journal_title：Neurology

authors： Tabert MH,Albert SM,Borukhova-Milov L,Camacho Y,Pelton G,Liu X,Stern Y,Devanand DP

更新日期：2002-03-12 00:00:00

abstract：OBJECTIVE:To investigate possible leptomeningeal contrast enhancement using postcontrast fluid-attenuated inversion recovery (FLAIR) MRI as an additional marker of inflammation in patients with multiple sclerosis (MS). METHODS:A cohort of 112 patients (73 women) with clinically definitive MS or a clinically isolated s...

journal_title：Neurology

authors： Eisele P,Griebe M,Szabo K,Wolf ME,Alonso A,Engelhardt B,Hennerici MG,Gass A

更新日期：2015-02-24 00:00:00

abstract：:Although the long-term effects of acute anoxia have been studied, the effects of chronic hypoxia on the developing human brain have received little attention. We studied children with a cyanotic congenital heart defect to assess the impact of chronic hypoxia by eight measures: neurologic examination, visual evoked res...

journal_title：Neurology

authors： O'Dougherty M,Wright FS,Loewenson RB,Torres F

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:To assess the surgical and hardware complications in a series of 81 consecutive patients undergoing subthalamic (STN) deep brain stimulation (DBS) for Parkinson disease (PD). METHODS:The authors prospectively documented surgical and hardware complications occurring at the time of surgery and at subsequent ne...

journal_title：Neurology

authors： Lyons KE,Wilkinson SB,Overman J,Pahwa R

更新日期：2004-08-24 00:00:00

abstract：:We performed a quantitative immunocytochemical study using a polyclonal antibody directed against choline acetyltransferase (ChAT) in the lower pontine reticular formation in four control subjects and three patients with progressive supranuclear palsy (PSP). In the normal brains, there was detectable ChAT-like immunor...

journal_title：Neurology

authors： Malessa S,Hirsch EC,Cervera P,Javoy-Agid F,Duyckaerts C,Hauw JJ,Agid Y

更新日期：1991-10-01 00:00:00

abstract：:A term neonate was being treated with intravenous phenytoin. To maintain a serum level above 10 micrograms per milliliter and abolish seizure activity, it was necessary to carry out repeated serum concentration measurements, administer several loading doses, and administer an unusually large maintenance dose (25 mg pe...

journal_title：Neurology

authors： Whelan HT,Hendeles L,Haberkern CM,Neims AH

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Pregnancy registries for women taking anticonvulsant drugs have been developed to determine more efficiently the fetal risks of each drug. A total of 722 drug-exposed pregnancies are needed to identify a sevenfold increase in the rate of occurrence of a specific abnormality, such as spina bifida, with a freq...

journal_title：Neurology

authors： Holmes LB,Baldwin EJ,Smith CR,Habecker E,Glassman L,Wong SL,Wyszynski DF

更新日期：2008-05-27 00:00:00

abstract：OBJECTIVE:The presence of cranial autonomic symptoms often leads to a misdiagnosis of "sinus headache" in adult migraineurs, leading to unnecessary treatments and delaying appropriate migraine therapy. In this study, we examined the frequency of cranial autonomic symptoms in pediatric/adolescent patients with migraine....

journal_title：Neurology

authors： Gelfand AA,Reider AC,Goadsby PJ

更新日期：2013-07-30 00:00:00