Increased frequency of isolated cleft palate in infants exposed to lamotrigine during pregnancy.

abstract：:We describe a 43-year-old neurologically intact patient who reported episodes of diplopia and oscillopsia associated with a right-beating nystagmus and a skew deviation. These symptoms and signs were related to a left posterior epileptic EEG discharge. We suggest that these ocular motor signs derived from an ictal act...

journal_title：Neurology

authors： Galimberti CA,Versino M,Sartori I,Manni R,Martelli A,Tartara A

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:In the late 19th century, a man with a psychogenic movement disorder was evaluated by many of the Philadelphia neurologists associated with Silas Weir Mitchell. In 1885, prior to the development of movie cameras or projectors, the patient was photographed by pioneering photographer Eadweard Muybridge, in col...

journal_title：Neurology

authors： Lanska DJ

更新日期：2015-01-27 00:00:00

abstract：:We studied a patient in a minimally conscious state using PET and cognitive evoked potentials. Cerebral metabolism was below half of normal values. Auditory stimuli with emotional valence (infant cries and the patient's own name) induced a much more widespread activation than did meaningless noise; the activation patt...

journal_title：Neurology

authors： Laureys S,Perrin F,Faymonville ME,Schnakers C,Boly M,Bartsch V,Majerus S,Moonen G,Maquet P

更新日期：2004-09-14 00:00:00

abstract：OBJECTIVE:To investigate possible correlations between tumor location and genetic alterations in a series of oligodendrogliomas. METHODS:A series of 158 consecutive oligodendrogliomas were retrospectively reviewed. In each case, the radiologic picture and the chromosome 1p (chr 1p) status of the tumor detected by the ...

journal_title：Neurology

authors： Laigle-Donadey F,Martin-Duverneuil N,Lejeune J,Crinière E,Capelle L,Duffau H,Cornu P,Broët P,Kujas M,Mokhtari K,Carpentier A,Sanson M,Hoang-Xuan K,Thillet J,Delattre JY

更新日期：2004-12-28 00:00:00

abstract：BACKGROUND:Benefit from carotid endarterectomy is greatest when performed within 2 weeks of a presenting TIA or stroke and decreases rapidly thereafter. OBJECTIVE:To determine the delays to carotid imaging and endarterectomy in Oxfordshire, UK, and the consequences for the effectiveness of stroke prevention. METHODS:...

journal_title：Neurology

authors： Fairhead JF,Mehta Z,Rothwell PM

更新日期：2005-08-09 00:00:00

abstract：:Current concepts suggest that avoidance of pulsatile stimulation of dopamine receptors in Parkinson's disease (PD) can prevent the onset of dyskinesia. In MPTP-treated primates, repeated administration of levodopa or other short-acting dopamine agonist drugs leads to the onset of marked involuntary movements. In contr...

journal_title：Neurology

authors： Jenner P

更新日期：2004-01-13 00:00:00

abstract：OBJECTIVE:To describe the clinical features, MRI findings, and pathogenesis of strokes producing internuclear ophthalmoplegia (INO) as an isolated or predominant clinical manifestation. METHODS:Thirty patients presenting with INO without (n = 12) or with (n = 18) minimal other neurologic signs were studied. MRI and an...

journal_title：Neurology

authors： Kim JS

更新日期：2004-05-11 00:00:00

abstract：OBJECTIVE:To identify the cause of hypokalemic periodic paralysis (HOKPP) in a family whose disease is not caused by a mutation in the dihydropyridine-sensitive (DHP) receptor alpha1-subunit gene (CACNA1S). BACKGROUND:Hypokalemic periodic paralysis is primarily caused by mutations within CACNA1S. Genetic heterogeneity...

journal_title：Neurology

authors： Bulman DE,Scoggan KA,van Oene MD,Nicolle MW,Hahn AF,Tollar LL,Ebers GC

更新日期：1999-12-10 00:00:00

abstract：:In a retrospective study of 103 corticosteroid-treated MS patients, the average rate of fracture events was 3.2% of the patients per year over 7.1 (+/- 5.7 SD) years at risk. Fractures of the ribs, pelvis, hip, or vertebrae occurred in 11 patients and became most common 5 years after starting steroids. Relatively high...

journal_title：Neurology

authors： Troiano RA,Jotkowitz A,Cook SD,Bansil S,Zito G

更新日期：1992-07-01 00:00:00

abstract：:Monocytes are recruited to active sites of multiple sclerosis (MS) demyelination and may promote local tissue injury by generating an inflammatory response, mediated in part by the production of toxic oxygen metabolites. Corticosteroids are frequently and effectively used to ameliorate MS exacerbations, despite inadeq...

journal_title：Neurology

authors： Fisher M,Levine PH,Doyle EM,Arpano MM,Bergeron DA,Cohen RA,Hoogasian JJ

更新日期：1991-02-01 00:00:00

abstract：:Using a 1.5-tesla GE Signa MR scanner, we imaged the brains of 14 right-handed Tourette's syndrome (TS) patients (11 men, three women), aged 18 to 49 years, who had minimal lifetime neuroleptic exposure. We also studied an equal number of normal controls individually matched for age, sex, and handedness and group-matc...

journal_title：Neurology

authors： Peterson B,Riddle MA,Cohen DJ,Katz LD,Smith JC,Hardin MT,Leckman JF

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Extrapyramidal signs (EPS) are common in Alzheimer disease (AD) and increase in prevalence as AD advances. The neuropathologic substrate responsible for EPS in AD remains to be fully characterized. METHODS:Subjects had a clinical diagnosis of AD confirmed by neuropathologic examination. EPS during life were...

journal_title：Neurology

authors： Burns JM,Galvin JE,Roe CM,Morris JC,McKeel DW

更新日期：2005-04-26 00:00:00

abstract：:A 46-year-old man had metastasis to the central tegmental tract of the pons with ipsilateral olivary hypertrophy. Although the phenomenon of palatal myochlonus has been repeatedly correlated with the finding of olivary hypertrophy, no palatal myoclonus was noted on repeated examinations. The clinical pathologic correl...

journal_title：Neurology

authors： Robin JJ,Alcala H

更新日期：1975-08-01 00:00:00

abstract：:We evaluated 14 patients with idiopathic optic neuritis, 50 years of age or older, within 1 month of symptomatic onset from 1980 through 1985. We obtained follow-up information from case records an average of 13 months after initial examination and from telephone interviews an average of 57 months after initial evalua...

journal_title：Neurology

authors： Jacobson DM,Thompson HS,Corbett JJ

更新日期：1988-12-01 00:00:00

abstract：:A patient presented with bilateral brachial plexus neuropathy which 2 weeks later evolved into a polyneuropathy involving all four extremities. On further investigation, the patient was found to have systemic lupus erythematosus. Treatment with steroids was accompanied by complete resolution of the neurologic findings...

journal_title：Neurology

authors： Bloch SL,Jarrett MP,Swerdlow M,Grayzel AI

更新日期：1979-12-01 00:00:00

abstract：OBJECTIVE:To correlate muscle biopsy findings with prebiopsy and postbiopsy clinical course and response to therapy in polymyositis (PM) and sporadic inclusion body myositis (IBM). BACKGROUND:Existence of pure PM has recently been questioned; subsequently, the definition and criteria for diagnosing PM were debated. M...

journal_title：Neurology

authors： Chahin N,Engel AG

更新日期：2008-02-05 00:00:00

abstract：:Hemorrhage complicating acute carbon monoxide poisoning is usually confined to the basal ganglia. The authors report three people with acute carbon monoxide poisoning manifesting selective or prominent white matter involvement complicated by hemorrhagic infarction on CT and MRI in one and by subcortical T2*-weighted M...

journal_title：Neurology

authors： Finelli PF,DiMario FJ Jr

更新日期：2004-09-28 00:00:00

abstract：OBJECTIVE:To analyze the frequency of neurologic events during commercial airline flights and to assess whether onboard emergency medical kits are adequate for in-flight neurologic emergencies. METHODS:Collaboration of the Mayo Clinic's Departments of Emergency Medicine and Medical Transportation Service and the Divis...

journal_title：Neurology

authors： Sirven JI,Claypool DW,Sahs KL,Wingerchuk DM,Bortz JJ,Drazkowski J,Caselli R,Zanick D

更新日期：2002-06-25 00:00:00

abstract：:We evaluated the accuracy and interobserver variability of selected ictal and postictal behavioral changes. Three observers, blinded to clinical history, EEG, and side of surgical resection, analyzed videotapes of 166 seizures in 38 patients, looking for lateralizing signs. Twenty-seven patients with temporal lobe res...

journal_title：Neurology

authors： Chee MW,Kotagal P,Van Ness PC,Gragg L,Murphy D,Lüders HO

更新日期：1993-12-01 00:00:00

abstract：:Although referrals for narcolepsy are increasing, physicians continue to confront obstacles in diagnosing and treating this condition. Patients with narcolepsy also face challenges at work, at school, and at home. One of the more disturbing problems is the lack of public awareness of the disorder and its potential the...

journal_title：Neurology

authors： Douglas NJ

更新日期：1998-02-01 00:00:00

abstract：:In a series of 100 patients exhibiting clinical and molecular features of facioscapulohumeral muscular dystrophy (FSHMD), five patients had conduction defects or arrhythmia in the absence of cardiovascular risk factors--namely, intraventricular conduction delay and supraventricular arrhythmia induced by electrophysiol...

journal_title：Neurology

authors： Laforêt P,de Toma C,Eymard B,Becane HM,Jeanpierre M,Fardeau M,Duboc D

更新日期：1998-11-01 00:00:00

abstract：:We attempted to define the role of subtle changes in the normal-appearing white matter (NAWM) in the development of disability in multiple sclerosis (MS). Twenty-seven clinically definite MS patients with either relapsing-remitting or chronic-progressive courses and 10 sex- and age-matched controls entered the study. ...

journal_title：Neurology

authors： Filippi M,Campi A,Dousset V,Baratti C,Martinelli V,Canal N,Scotti G,Comi G

更新日期：1995-03-01 00:00:00

abstract：OBJECTIVES:To describe the clinical, CSF, and radiologic findings and long-term follow-up in a cohort of patients with acute disseminated encephalomyelitis (ADEM), and to determine possible prognostic factors for progression to MS. METHODS:Forty adults (28 women, mean age 33.5 years) diagnosed with ADEM were analyzed....

journal_title：Neurology

authors： Schwarz S,Mohr A,Knauth M,Wildemann B,Storch-Hagenlocher B

更新日期：2001-05-22 00:00:00

abstract：:We studied the effects of bromocriptine on periodic limb movements in sleep (PLMS) of narcoleptic patients. Bromocriptine significantly reduced the number and index of PLMS without improving the nocturnal sleep disruption in that disorder. These results support the hypothesis that dopaminergic mechanisms are involved ...

journal_title：Neurology

authors： Boivin DB,Lorrain D,Montplaisir J

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVE:We conducted a nationwide case-control study in Sweden to test the hypothesis that specific clinical characteristics are associated with increased risk of sudden unexpected death in epilepsy (SUDEP). METHODS:The study included 255 SUDEP cases (definite and probable) and 1,148 matched controls. Clinical infor...

journal_title：Neurology

authors： Sveinsson O,Andersson T,Mattsson P,Carlsson S,Tomson T

更新日期：2020-01-28 00:00:00

abstract：:Radiation rhombencephalopathy and radiation myelopathy may occur in patients months or years after radiotherapy for malignancy of the head and neck. We obtained multimodal evoked potentials longitudinally in 26 patients with proven nasopharyngeal carcinoma. Recordings were made before radiotherapy and at 1 week, 3 mon...

journal_title：Neurology

authors： Tang LM,Chen ST,Hsu WC,Leung WM

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVE:To assess longitudinal follow-up of the incidence of multiple sclerosis (MS) through five decades and estimate the prevalence rate in Hordaland County, Norway, on January 1, 2003. METHODS:All patients with MS diagnosed from 1953 to 2003 were identified in the patient records of the Department of Neurology, H...

journal_title：Neurology

authors： Grytten N,Glad SB,Aarseth JH,Nyland H,Midgard R,Myhr KM

更新日期：2006-01-24 00:00:00

abstract：:Previous research has shown that the Mini-Mental State Examination (MMS) is biased as a measure of cognitive impairment in minority and low-education patients. The purpose of this study was to (1) develop a statistical correction for effects of age and education and (2) test the efficacy of the statistically adjusted ...

journal_title：Neurology

authors： Mungas D,Marshall SC,Weldon M,Haan M,Reed BR

更新日期：1996-03-01 00:00:00

abstract：:Glucocorticoid therapy slows the progression of Duchenne muscular dystrophy. In muscle cultures, the addition of the glucocorticoid methylprednisolone increases myogenesis in most normal mixed and clonal cultures. Conversely, in some normal clonal and most dystrophic cultures, methylprednisolone inhibits fusion. Howev...

journal_title：Neurology

authors： Hardiman O,Sklar RM,Brown RH Jr

更新日期：1993-02-01 00:00:00

abstract：OBJECTIVE:To test the diagnostic accuracy of the horizontal head impulse test (h-HIT) of vestibulo-ocular reflex (VOR) function in distinguishing acute peripheral vestibulopathy (APV) from stroke. Most patients with acute vertigo, nausea/vomiting, and unsteady gait have benign APV (vestibular neuritis or labyrinthitis)...

journal_title：Neurology

authors： Newman-Toker DE,Kattah JC,Alvernia JE,Wang DZ

更新日期：2008-06-10 00:00:00