Abstract:
:We describe a 43-year-old neurologically intact patient who reported episodes of diplopia and oscillopsia associated with a right-beating nystagmus and a skew deviation. These symptoms and signs were related to a left posterior epileptic EEG discharge. We suggest that these ocular motor signs derived from an ictal activation of the vestibular cortex, which in turn activated descending projections to the vestibular nuclei, leading to both a dynamic (right-beating nystagmus) and a static (skew deviation) vestibular imbalance.
journal_name
Neurologyjournal_title
Neurologyauthors
Galimberti CA,Versino M,Sartori I,Manni R,Martelli A,Tartara Adoi
10.1212/wnl.50.5.1469subject
Has Abstractpub_date
1998-05-01 00:00:00pages
1469-72issue
5eissn
0028-3878issn
1526-632Xjournal_volume
50pub_type
杂志文章相关文献
NEUROLOGY文献大全abstract:OBJECTIVE:To investigate the prevalence of headaches in a Chinese elderly population. BACKGROUND:There are few headache surveys in the elderly. Previous studies have shown a low headache prevalence in Chinese. METHODS: TARGET POPULATION:eligible registered residents > or = 65 years old (N = 2,003) in two townships o...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.49.1.195
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVES:To estimate the risk to public safety posed by drivers with epilepsy, the authors compared annual totals and disease-specific risk for fatal crashes associated with seizures and other medical conditions. They compared individual risks for fatal crashes due to seizures and other causes of mortality in patient...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000138590.00074.9a
更新日期:2004-09-28 00:00:00
abstract:OBJECTIVE:To determine the risk, predictors, and prognosis of independence loss and institutionalization in patients with early Parkinson disease (PD). METHODS:We conducted a prospective population-based 5-year longitudinal study following 189 patients with incident PD and 174 controls matched for age, sex, and comorb...
journal_title:Neurology
pub_type: 杂志文章,多中心研究
doi:10.1212/WNL.0000000000003213
更新日期:2016-10-11 00:00:00
abstract:BACKGROUND:Optimal treatment remains uncertain for patients with cognitive impairment that persists or returns after standard IV antibiotic therapy for Lyme disease. METHODS:Patients had well-documented Lyme disease, with at least 3 weeks of prior IV antibiotics, current positive IgG Western blot, and objective memory...
journal_title:Neurology
pub_type: 杂志文章,随机对照试验
doi:10.1212/01.WNL.0000284604.61160.2d
更新日期:2008-03-25 00:00:00
abstract::Using the centralized diagnostic data resource for the population of Rochester, Minnesota, we determined the prevalence of medically diagnosed dementia for this community. There were 289 individuals with dementia who were residing in Rochester on January 1, 1975: 208 women and 81 men. The overall age- and sex-adjusted...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.39.6.773
更新日期:1989-06-01 00:00:00
abstract::The authors assessed the referral pattern and outcome in patients with Guillain-Barré syndrome (n = 266) after the introduction of intravenous immunoglobulin (IVIg). Fewer patients were transferred from small to large hospitals after the introduction of IVIg (p = 0.05). This did not result in a worse outcome in patien...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.56.4.564
更新日期:2001-02-27 00:00:00
abstract:BACKGROUND:Metals are suspected of being involved in the pathogenesis of various neurologic diseases. We previously found a complex imbalance in serum chemical elements and oxidative status in patients with clinically definite multiple sclerosis (CDMS). OBJECTIVE:To understand whether this imbalance affects people wit...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e31820af7de
更新日期:2011-02-08 00:00:00
abstract::We retrospectively studied the effects of changing antiepileptic drug levels on patterns of seizure discharge in 8 patients investigated with intracerebral electrodes during presurgical evaluation. We compared seizures recorded at high levels of medication to seizures recorded at low levels for changes in seizure dura...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.40.3_part_1.407
更新日期:1990-03-01 00:00:00
abstract:OBJECTIVE:To investigate the prevalence and nature of cognitive changes associated with sporadic amyotrophic lateral sclerosis (ALS) using a large scale study. METHODS:Consecutive patients with sporadic ALS (n = 279) underwent comprehensive neurologic evaluation and neuropsychological testing. Testing data from normal...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000172911.39167.b6
更新日期:2005-08-23 00:00:00
abstract:OBJECTIVE:The purpose of this study was to assess the prevalence of and to identify epidemiologic, genetic, electrophysiologic, and neuroanatomic risk factors for autism spectrum disorders (ASD) in a cohort of patients with tuberous sclerosis complex (TSC). METHODS:A total of 103 patients with TSC were evaluated for A...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e3182104347
更新日期:2011-03-15 00:00:00
abstract:OBJECTIVE:To investigate specificity and significance of dynamic changes of the cervical dural sac and spinal cord during neck flexion in juvenile muscular atrophy of the distal upper extremity. BACKGROUND:The disorder affects young people-predominantly men-and is progressive for several years. One autopsy case showed...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.54.10.1922
更新日期:2000-05-23 00:00:00
abstract::We reviewed the clinical course of nine patients with neuro-Behçet's disease to assess difficulties in making this diagnosis. Factors delaying proper diagnosis included lack of accurate history and physical examination, lack of recognition of an underlying systemic syndrome and its relationship to the neurologic sympt...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.45.9.1754
更新日期:1995-09-01 00:00:00
abstract:OBJECTIVE:Spinal cord (SC) lesions are frequently found in multiple sclerosis (MS), but are rare in healthy aging and cerebrovascular patients. Our aim was to analyze the contribution of SC involvement in clinically isolated syndrome (CIS) in diagnosing MS according the McDonald 2010 criteria and in predicting conversi...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e31827b1a67
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:Quality of neurologic emergency management in an under-resourced country may be improved by standard operating procedures (SOPs). METHODS:Neurologic SOPs were implemented in a large urban (Banjul) and a small rural (Brikama) hospital in the Gambia. As quality indicators of neurologic emergency management, pe...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000004080
更新日期:2017-07-11 00:00:00
abstract:BACKGROUND:After 1 to 4 years, seizure-free children with epilepsy are encouraged to stop daily antiepileptic drug (AED) treatment. Approximately 70% are successful. The authors examined how often intractable epilepsy follows discontinuation of AED treatment in a population-based cohort of children with epilepsy. METH...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.WNL.0000154517.82748.A7
更新日期:2005-03-22 00:00:00
abstract:OBJECTIVES:Using high-resolution structural MRI, we endeavored to study the relationships among APOE ε4, hippocampal subfield and stratal anatomy, and episodic memory. METHODS:Using a cross-sectional design, we studied 11 patients with Alzheimer disease dementia, 14 patients with amnestic mild cognitive impairment, an...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000000154
更新日期:2014-02-25 00:00:00
abstract:OBJECTIVE:To evaluate the effectiveness of opicapone as add-on to levodopa and the effects of switching from entacapone over 1 year of treatment in patients with fluctuating Parkinson disease. METHODS:After completion of a placebo- and entacapone-controlled double-blind study of opicapone (5, 25, or 50 mg), 495 patien...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000005557
更新日期:2018-05-22 00:00:00
abstract::Despite strong evidence of the importance of hereditary factors in the etiology of Tourette's syndrome (TS), research findings have consistently pointed to a role of environmental influences. A recent line of research has suggested that tic disorders and associated behavioral disturbances, such as obsessive-compulsive...
journal_title:Neurology
pub_type: 评论,杂志文章,评审
doi:10.1212/wnl.50.6.1530
更新日期:1998-06-01 00:00:00
abstract::Genetic factors are important in Alzheimer disease (AD) and Parkinson disease but have not been well characterized in Lewy body dementia (LBD). The authors obtained family history in patients from an autopsy series of AD and LBD and in living healthy controls. A family history of dementia was more common in both LBD a...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000219812.20616.b3
更新日期:2006-06-27 00:00:00
abstract::The motor effects of direct agonists which act selectively on certain dopamine receptors were studied in monkeys rendered hemiparkinsonian by unilateral intracarotid injection of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). The D-2 dopamine agonist, LY 171555, but not the D-1 agonist, SKF 38393, reduced parkin...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.37.10.1592
更新日期:1987-10-01 00:00:00
abstract:OBJECTIVE:The primary objective of this research was to characterize the movement disorders associated with FOXG1 mutations. METHODS:We identified patients with FOXG1 mutations who were referred to either a tertiary movement disorder clinic or tertiary epilepsy service and retrospectively reviewed medical records, cli...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000002585
更新日期:2016-05-10 00:00:00
abstract::There have been few descriptions of spontaneous epidural hematoma of the spinal cord in children. Duration of symptoms in previous cases has varied from hours to days. We recently evaluated a 6-year-old girl with cord compression from an extradural clot, who complained of thoracic back pain for 3 months before becomin...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.29.1.120
更新日期:1979-01-01 00:00:00
abstract:OBJECTIVES:The authors report the results of a prospective, placebo-controlled, randomized study to evaluate the effectiveness of 3,4-diaminopyridine (DAP) in patients with Lambert-Eaton myasthenic syndrome (LEMS) and to determine the acute and long-term side effects of DAP. METHODS:Twenty-six patients with LEMS compl...
journal_title:Neurology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1212/wnl.54.3.603
更新日期:2000-02-08 00:00:00
abstract:OBJECTIVE:To investigate the relationship between the presence of a circadian body temperature rhythm and behaviorally assessed consciousness levels in patients with disorders of consciousness (DOC; i.e., vegetative state/unresponsive wakefulness syndrome or minimally conscious state). METHODS:In a cross-sectional stu...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000003942
更新日期:2017-05-16 00:00:00
abstract::Following commissurotomy, it is usually the case that information presented to the left hemisphere can be named and described, while information presented to the mute, right hemisphere cannot be spoken about. In the present study, it was discovered that under special test conditions, an MRI-verified, callosally sectio...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.37.4.682
更新日期:1987-04-01 00:00:00
abstract:BACKGROUND:Bee sting therapy is increasingly used to treat patients with multiple sclerosis (MS) in the belief that it can stabilize or ameliorate the disease. However, there are no clinical studies to justify its use. METHODS:In a randomized, crossover study, we assigned 26 patients with relapsing-remitting or relaps...
journal_title:Neurology
pub_type: 杂志文章,随机对照试验
doi:10.1212/01.wnl.0000184442.02551.4b
更新日期:2005-12-13 00:00:00
abstract::Although motor fibers in the sural nerve were already described in three individuals, this nerve is considered purely sensory. We investigated the occurrence of motor fibers in 331 sural nerves of 207 individuals. We found motor fibers in 15 nerves (4.5%) or in 13 individuals (6.2%). The identification of motor fibers...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.49.6.1725
更新日期:1997-12-01 00:00:00
abstract:BACKGROUND:Ullrich congenital muscular dystrophy (UCMD) is a form of merosin-positive congenital muscular dystrophy characterized by proximal contractures, distal laxity, rigidity of the spine, and respiratory complications. Recently, a deficiency of collagen VI on muscle and skin biopsy together with recessive mutatio...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.58.9.1354
更新日期:2002-05-14 00:00:00
abstract::With the use of the newer antidepressants beyond the traditional tricyclics and monoamine oxidase inhibitors, newer options in headache prophylaxis are provided as well as the potential for undesirable and even potentially life-threatening interactions between medications. In this article, four patient reports of a sp...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.51.1.274
更新日期:1998-07-01 00:00:00
abstract::The authors estimated the sample sizes needed for exploratory trials of MS assessing the efficacy of new treatments in reducing the number of new enhancing lesions vs those of interferon-beta or glatiramer acetate. The sample sizes per arm ranged from 868 (effect: 20%) to 94 (effect: 50%) for patients with relapsing-r...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.57.10.1883
更新日期:2001-11-27 00:00:00