Factors influencing outcome of prednisone dose reduction in myasthenia gravis.

abstract：:In six patients with cryptococcal meningitis, diagnosis was made by routine cytologic examination of cerebrospinal fluid (CSF). A seventh patient had a false-positive cryptococcal antigen titer, and no organism was seen on SCF examination. The patient had herpes simplex encephalitis on brain biopsy. Cytologic examinat...

journal_title：Neurology

authors： Bernad PG,Szyfelbein WM,Weiss HD,Richardson EP Jr

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVE:To study the prognostic significance of multiple novel biomarkers in combination after ischemic stroke. METHODS:We derived data from the China Antihypertensive Trial in Acute Ischemic Stroke, and 12 informative biomarkers were measured. The primary outcome was the combination of death and major disability (m...

journal_title：Neurology

authors： Zhong C,Zhu Z,Wang A,Xu T,Bu X,Peng H,Yang J,Han L,Chen J,Xu T,Peng Y,Wang J,Li Q,Ju Z,Geng D,He J,Zhang Y

更新日期：2019-01-22 00:00:00

abstract：:Of 49 patients with nonconvulsive seizures studied with continuous EEG monitoring, the overall mortality was 33% (16/49). Of the 23 patients with nonconvulsive status epilepticus (NCSE), 13 died (mortality 57%). Individual variables significantly associated with mortality were age, presence of NCSE, seizure duration, ...

journal_title：Neurology

authors： Young GB,Jordan KG,Doig GS

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVE:To investigate the association between early depressive behavior after stroke onset and occurrence of poststroke depression (PSD) at 3- and 12-month follow-up evaluations. METHODS:The study prospectively included 273 patients with first-ever single uncomplicated ischemic stroke. In the stroke unit, nurses sc...

journal_title：Neurology

authors： Carota A,Berney A,Aybek S,Iaria G,Staub F,Ghika-Schmid F,Annable L,Guex P,Bogousslavsky J

更新日期：2005-02-08 00:00:00

abstract：OBJECTIVE:To assess dyskinesia frequency in a population-based cohort of patients with Parkinson disease (PD). Dyskinesia complicates levodopa treatment and affects quality of life. METHODS:Utilizing the 1991-2010 population-based, parkinsonism-incident cohort of Olmsted County, MN (n = 669), accessed via the Rocheste...

journal_title：Neurology

authors： Turcano P,Mielke MM,Bower JH,Parisi JE,Cutsforth-Gregory JK,Ahlskog JE,Savica R

更新日期：2018-12-11 00:00:00

abstract：:We recorded interictal spikes with closely spaced scalp electrodes and sphenoidal electrodes in four patients with temporal lobe epilepsy. We used multiple dipole modeling to study the number, three-dimensional intracerebral location, time activity, and functional relationship of the neuronal sources underlying the ep...

journal_title：Neurology

authors： Baumgartner C,Lindinger G,Ebner A,Aull S,Serles W,Olbrich A,Lurger S,Czech T,Burgess R,Lüders H

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVE:In this study, we compared a cognition-specific computer-based cognitive training program with a motion-controlled computer sports game that is not cognition-specific for their ability to enhance cognitive performance in various cognitive domains in patients with Parkinson disease (PD). METHODS:Patients with...

journal_title：Neurology

authors： Zimmermann R,Gschwandtner U,Benz N,Hatz F,Schindler C,Taub E,Fuhr P

更新日期：2014-04-08 00:00:00

abstract：:We conducted a randomized double-blind comparison of three doses of the novel antiepileptic drug (AED) topiramate (200, 400, and 600 mg/day) and placebo as adjunctive therapy in patients with refractory partial onset epilepsy receiving one or two other AEDs at therapeutic concentrations. A total of 181 patients comple...

journal_title：Neurology

authors： Faught E,Wilder BJ,Ramsay RE,Reife RA,Kramer LD,Pledger GW,Karim RM

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVE:To determine whether the CT angiography (CTA) spot sign marks bleeding complications during and after surgery for spontaneous intracerebral hemorrhage (ICH). METHODS:In a 2-center study of consecutive spontaneous ICH patients who underwent CTA followed by surgical hematoma evacuation, 2 experienced readers (...

journal_title：Neurology

authors： Brouwers HB,Raffeld MR,van Nieuwenhuizen KM,Falcone GJ,Ayres AM,McNamara KA,Schwab K,Romero JM,Velthuis BK,Viswanathan A,Greenberg SM,Ogilvy CS,van der Zwan A,Rinkel GJ,Goldstein JN,Klijn CJ,Rosand J

更新日期：2014-09-02 00:00:00

abstract：:Because hereditary hyperekplexia results from a defect in the glycine receptor, we studied in five patients several spinal inhibitory pathways that are thought to use either glycine or gamma-aminobutyric acid as a neurotransmitter. Three patients had a mutation in the alpha1 subunit of the glycine receptor, whereas tw...

journal_title：Neurology

authors： Floeter MK,Andermann F,Andermann E,Nigro M,Hallett M

更新日期：1996-03-01 00:00:00

abstract：:We analyzed the frequency of cardiac embolic sources in 62 patients with acute lacunar stroke vs 50 controls. In post hoc analysis, 11 patients with lacunar stroke having neither hypertension nor diabetes mellitus (non-HDM group) had a higher frequency of right-to-left shunt (RLS) (82%) than patients with risk factors...

journal_title：Neurology

authors： Ueno Y,Kimura K,Iguchi Y,Shibazaki K,Inoue T,Urabe T

更新日期：2007-02-13 00:00:00

abstract：:Two hundred thirty-nine patients with Bell palsy were randomly distributed into prednisone-treated and control groups. Patients were followed until complete recovery or for 1 year. In the steroid-treated and control groups, respectively, incomplete recovery of facial strength occurred in 12 percent and 20 percent; mot...

journal_title：Neurology

authors： Wolf SM,Wagner JH,Davidson S,Forsythe A

更新日期：1978-02-01 00:00:00

abstract：:Management of low-grade gliomas continues to be a challenging task, because CT and MRI do not always differentiate from nontumoral lesions. Furthermore, tumor extent and aggressiveness often remain unclear because of a lack of contrast enhancement. Previous studies indicated that large neutral amino acid tracers accum...

journal_title：Neurology

authors： Herholz K,Hölzer T,Bauer B,Schröder R,Voges J,Ernestus RI,Mendoza G,Weber-Luxenburger G,Löttgen J,Thiel A,Wienhard K,Heiss WD

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:We pooled the results of studies on natural history of cavernous malformations (CM) to calculate point estimates and investigate main sources of heterogeneity. METHODS:We searched MEDLINE, EMBASE, and ISI Web of Science for relevant studies published before May 2015. We used fixed or random effects models an...

journal_title：Neurology

authors： Taslimi S,Modabbernia A,Amin-Hanjani S,Barker FG 2nd,Macdonald RL

更新日期：2016-05-24 00:00:00

abstract：:Idiopathic cervical dystonia (CD) is the most common of the adult-onset focal dystonias. It manifests as involuntary muscle contractions that cause twisting or turning of the neck. The resulting abnormal head and neck postures are heterogeneous in their presentation. Because of the variable presentation of the disease...

journal_title：Neurology

authors： Stacy M

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and tolerability of lamotrigine (LTG) for the treatment of pain in HIV-associated sensory neuropathies. METHODS:In a randomized, double-blind study, patients with HIV-associated distal sensory polyneuropathy (DSP) received LTG or placebo during a 7-week dose escalation phase followed...

journal_title：Neurology

authors： Simpson DM,McArthur JC,Olney R,Clifford D,So Y,Ross D,Baird BJ,Barrett P,Hammer AE,Lamotrigine HIV Neuropathy Study Team.

更新日期：2003-05-13 00:00:00

abstract：OBJECTIVE:To evaluate published evidence of efficacy and safety of pharmacologic treatments for childhood spasticity due to cerebral palsy. METHODS:A multidisciplinary panel systematically reviewed relevant literature from 1966 to July 2008. RESULTS:For localized/segmental spasticity, botulinum toxin type A is establ...

journal_title：Neurology

authors： Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society.,Delgado MR,Hirtz D,Aisen M,Ashwal S,Fehlings DL,McLaughlin J,Morrison LA,Shrader MW,Tilton A,Vargus-Adams

更新日期：2010-01-26 00:00:00

abstract：OBJECTIVE:To evaluate the utility of MRI hippocampal and entorhinal cortex atrophy in predicting conversion from mild cognitive impairment (MCI) to Alzheimer disease (AD). METHODS:Baseline brain MRI was performed in 139 patients with MCI, broadly defined, and 63 healthy controls followed for an average of 5 years (ran...

journal_title：Neurology

authors： Devanand DP,Pradhaban G,Liu X,Khandji A,De Santi S,Segal S,Rusinek H,Pelton GH,Honig LS,Mayeux R,Stern Y,Tabert MH,de Leon MJ

更新日期：2007-03-13 00:00:00

abstract：:Recent epidemiologic studies of multiple sclerosis (MS) in Australia defined the State of Queensland as a medium-frequency zone and the more southerly placed cities of Perth, Newcastle, and Hobart as high-frequency zones. Clinical profiles in the patient populations of both frequency zones were remarkably similar in m...

journal_title：Neurology

authors： Hammond SR,English D,de Wytt C,Maxwell IC,Millingen KS,Stewart-Wynne EG,McLeod JG,McCall MG

更新日期：1988-06-01 00:00:00

abstract：:In spinal cords from seven amyotrophic lateral sclerosis (ALS) patients and four controls, we found no difference in thyrotropin-releasing hormone (TRH) concentration relative to protein content, but there was a reduction per tissue wet weight in ALS. Immunohistochemical localization of TRH in ALS cord was unaltered. ...

journal_title：Neurology

authors： Jackson IM,Adelman LS,Munsat TL,Forte S,Lechan RM

更新日期：1986-09-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that ApoE isoforms affect mitochondrial structure and function that are related to cognitive impairment in Alzheimer disease (AD), we systematically investigated the effects of ApoE isoforms on mitochondrial biogenesis and dynamics, oxidative stress, synapses, and cognitive performance ...

journal_title：Neurology

authors： Yin J,Reiman EM,Beach TG,Serrano GE,Sabbagh MN,Nielsen M,Caselli RJ,Shi J

更新日期：2020-06-09 00:00:00

abstract：:We performed a clinical study and linkage analysis on 278 subjects (66 affected) belonging to eight families with X-linked dominant Charcot-Marie-Tooth (CMT) neuropathy. This form affects 11.8% of CMT patients in Iowa. Motor nerve conduction velocities (MNCVs) were significantly slowed consistent with type 1 CMT. Fift...

journal_title：Neurology

authors： Ionasescu VV,Trofatter J,Haines JL,Ionasescu R,Searby C

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:To determine the role of weight loss in the treatment of idiopathic intracranial hypertension (IIH) in obese women. METHODS:Chart review of 250 patients with suspected IIH revealed 58 women who met our criteria, did not undergo early surgical intervention, and had adequate documentation of visual status, pap...

journal_title：Neurology

authors： Kupersmith MJ,Gamell L,Turbin R,Peck V,Spiegel P,Wall M

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVE:To investigate specificity and significance of dynamic changes of the cervical dural sac and spinal cord during neck flexion in juvenile muscular atrophy of the distal upper extremity. BACKGROUND:The disorder affects young people-predominantly men-and is progressive for several years. One autopsy case showed...

journal_title：Neurology

authors： Hirayama K,Tokumaru Y

更新日期：2000-05-23 00:00:00

abstract：:Migraine does not increase the risk for complications of pregnancy for the mother or for the fetus: the incidences of toxemia, miscarriages, abnormal labour, congenital anomalies, and stillbirths are comparable to those of the general population. Several retrospective studies have shown a tendency for migraine to impr...

journal_title：Neurology

authors： Aubé M

更新日期：1999-01-01 00:00:00

abstract：:We reviewed the clinical course of nine patients with neuro-Behçet's disease to assess difficulties in making this diagnosis. Factors delaying proper diagnosis included lack of accurate history and physical examination, lack of recognition of an underlying systemic syndrome and its relationship to the neurologic sympt...

journal_title：Neurology

authors： Devlin T,Gray L,Allen NB,Friedman AH,Tien R,Morgenlander JC

更新日期：1995-09-01 00:00:00

abstract：:Extracranial and intracranial angioplasty and stenting of the cerebral vessels are being performed more frequently. One clinical trial demonstrated equivalent outcomes between extracranial carotid angioplasty and carotid endarterectomy, but the results in both groups were suboptimal. Concerns remain about the iatrogen...

journal_title：Neurology

authors： Chaturvedi S,Fessler R

更新日期：2002-09-10 00:00:00

abstract：INTRODUCTION:As clinical trials move toward earlier intervention, we sought to redefine the β-amyloid (Aβ)-PET threshold based on the lowest point in a baseline distribution that robustly predicts future Aβ accumulation and cognitive decline in 3 independent samples of clinically normal individuals. METHODS:Sequential...

journal_title：Neurology

authors： Farrell ME,Jiang S,Schultz AP,Properzi MJ,Price JC,Becker JA,Jacobs HIL,Hanseeuw BJ,Rentz DM,Villemagne VL,Papp KV,Mormino EC,Betensky RA,Johnson KA,Sperling RA,Buckley RF,Alzheimer's Disease Neuroimaging Initiative and t

更新日期：2021-01-26 00:00:00

abstract：:Three neuropathologists evaluated brain sections from 43 aged subjects for the presence of Alzheimer's disease. Moderate-to-substantial agreement was obtained. After discussion of disparate diagnoses, agreement was almost perfect for standardized and substantial for personal criteria. We conclude that reproducibility ...

journal_title：Neurology

authors： Paulus W,Bancher C,Jellinger K

更新日期：1992-02-01 00:00:00

abstract：OBJECTIVE:To study the distribution of prior scoliosis among patients with primary adult-onset cervical dystonia (CD) and matched control subjects. METHODS:Case and control subjects were selected among consecutive outpatients attending four Italian centers. Control outpatients were matched for age (+/-5 years), sex, a...

journal_title：Neurology

authors： Defazio G,Abbruzzese G,Girlanda P,Buccafusca M,Currà A,Marchese R,Martino D,Masi G,Mazzella L,Vacca L,Livrea P,Berardelli A

更新日期：2003-03-25 00:00:00