Abstract:
:GM1 gangliosidosis is usually a pediatric disease caused by hereditary acid beta-galactosidase deficiency. There have been a few cases in adults. We saw a 51-year-old Japanese man with type 3 GM1 gangliosidosis who was manifesting dementia, dysarthria, gait disturbance, and limb rigidity. Radiologic studies showed platyspondylia, acetabular hypoplasia, and flattened femoral heads. Biochemical analysis revealed generalized acid beta-galactosidase deficiency.
journal_name
Neurologyjournal_title
Neurologyauthors
Ohta K,Tsuji S,Mizuno Y,Atsumi T,Yahagi T,Miyatake Tdoi
10.1212/wnl.35.10.1490subject
Has Abstractpub_date
1985-10-01 00:00:00pages
1490-4issue
10eissn
0028-3878issn
1526-632Xjournal_volume
35pub_type
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