Associations with autoimmune disorders and HLA class I and II antigens in inclusion body myositis.

Abstract:

:Whether autoimmune mechanisms play a role in the pathogenesis of inclusion body myositis (IBM) is unknown. Human leukocyte antigen (HLA) analysis in 52 patients, including 17 with autoimmune disorders (AIDs), showed that patients were more likely to have antigens from the autoimmune-prone HLA-B8-DR3 ancestral haplotype than healthy control subjects, irrespective of the presence of AIDs. Patients lacked the apparently protective HLA-DR53 antigen. The results provide further support for an autoimmune basis in IBM.

journal_name

Neurology

journal_title

Neurology

authors

Badrising UA,Schreuder GM,Giphart MJ,Geleijns K,Verschuuren JJ,Wintzen AR,Maat-Schieman ML,van Doorn P,van Engelen BG,Faber CG,Hoogendijk JE,de Jager AE,Koehler PJ,de Visser M,van Duinen SG,Dutch IBM Study Group.

doi

10.1212/01.wnl.0000148588.15052.4c

subject

Has Abstract

pub_date

2004-12-28 00:00:00

pages

2396-8

issue

12

eissn

0028-3878

issn

1526-632X

pii

63/12/2396

journal_volume

63

pub_type

杂志文章
  • Traumatic brain injury preceding clinically diagnosed α-synucleinopathies: A case-control study.

    abstract:OBJECTIVE:To determine the association between traumatic brain injury (TBI) and any clinically diagnosed α-synucleinopathy including Parkinson disease (PD), dementia with Lewy bodies (DLB), PD dementia (PDD), and multiple system atrophy (MSA). METHODS:Using the medical records-linkage system of the Rochester Epidemiol...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000008995

    authors: Hasan S,Mielke MM,Turcano P,Ahlskog JE,Bower JH,Savica R

    更新日期:2020-02-25 00:00:00

  • Predicting developmental outcomes in preterm infants: A simple white matter injury imaging rule.

    abstract:OBJECTIVE:To develop a simple imaging rule to predict neurodevelopmental outcomes at 4.5 years in a cohort of preterm neonates with white matter injury (WMI) based on lesion location and examine whether clinical variables enhance prediction. METHODS:Sixty-eight preterm neonates born 24-32 weeks' gestation (median 27.7...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000008172

    authors: Cayam-Rand D,Guo T,Grunau RE,Benavente-Fernández I,Synnes A,Chau V,Branson H,Latal B,McQuillen P,Miller SP

    更新日期:2019-09-24 00:00:00

  • Acute effects of acetazolamide in hyperkalemic periodic paralysis.

    abstract::We studied the effect of acetazolamide on plasma potassium in normals and in two patients with hyperkalemic periodic paralysis. Administration of acetazolamide for 48 hours lowered mean plasma potassium in normals from 4.01 to 3.56 mEq per liter (p less than 0.001) and in the patients from 4.55 to 4.00 mEq per liter (...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.31.6.725

    authors: Riggs JE,Griggs RC,Moxley RT 3rd,Lewis ED

    更新日期:1981-06-01 00:00:00

  • Effects of cannabis on cognitive function in patients with multiple sclerosis.

    abstract:BACKGROUND:While neuropsychological deficits have been reported in healthy individuals who use street cannabis, data in patients with multiple sclerosis (MS) are lacking. Given that MS is associated with cognitive deterioration, the aim of this study was to determine the neuropsychological effects of cannabis use in th...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e318212ab0c

    authors: Honarmand K,Tierney MC,O'Connor P,Feinstein A

    更新日期:2011-03-29 00:00:00

  • Neurofilament light and tau as blood biomarkers for sports-related concussion.

    abstract:OBJECTIVE:To compare neurofilament light (NfL) and tau as blood-based biomarkers for acute sports-related concussion (SRC) and determine whether their concentrations at different time points after the injury are associated with prolonged time to return to play (RTP). METHODS:A total of 288 professional hockey players ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000005518

    authors: Shahim P,Tegner Y,Marklund N,Blennow K,Zetterberg H

    更新日期:2018-05-15 00:00:00

  • Neuroanatomy of the self: evidence from patients with frontotemporal dementia.

    abstract:OBJECTIVE:To evaluate the frequency and types of change in "self" seen in frontotemporal dementia (FTD) and to determine the relative involvement of the nondominant and dominant frontal and temporal brain regions in FTD patients with or without changes in a sense of self using neuropsychology tests and neuroimaging. B...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.57.5.817

    authors: Miller BL,Seeley WW,Mychack P,Rosen HJ,Mena I,Boone K

    更新日期:2001-09-11 00:00:00

  • Reciprocal inhibition in cerebral palsy.

    abstract::We studied reciprocal inhibition by recording the changes in firing probability of single motor units of the tibialis anterior muscle following stimulation of low-threshold afferents in the posterior tibial nerve. In 15 patients with cerebral palsy, the inhibition was as great or greater than normal. We found no evide...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.40.4.653

    authors: Berbrayer D,Ashby P

    更新日期:1990-04-01 00:00:00

  • Androgen receptor abnormality in X-linked spinal and bulbar muscular atrophy.

    abstract::X-linked spinal and bulbar muscular atrophy (SBMA) is usually associated with feminization and hypogonadism. We were unable to find androgen receptor (AR) in the scrotal skin of three patients with SBMA, and propose that AR abnormality is the cause of the disease. ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.42.9.1724

    authors: Matsuura T,Demura T,Aimoto Y,Mizuno T,Moriwaka F,Tashiro K

    更新日期:1992-09-01 00:00:00

  • Firing rates of human motor units in partially denervated muscle.

    abstract::Single motor unit firing rates were measured from the first dorsal interosseous muscle (FDI) of normal subjects and patients with partial denervation of that muscle. Motor unit discharges were recorded at various levels of voluntary, stationary, isometric contraction of the FDI. The mean increase in firing rate associ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.28.12.1241

    authors: Miller RG,Sherratt M

    更新日期:1978-12-01 00:00:00

  • Ischemic stroke subtypes among Mexican Americans and non-Hispanic whites: the BASIC Project.

    abstract::Ischemic stroke subtype distribution was compared between Mexican Americans (MAs) and non-Hispanic whites (NHWs) in a community-based stroke surveillance study in Nueces County, TX. There was no difference in the distribution of stroke subtype by ethnicity (p = 0.19). There was a similar proportion of small-vessel and...

    journal_title:Neurology

    pub_type: 杂志文章,评审

    doi:10.1212/01.wnl.0000133212.99040.07

    authors: Uchino K,Risser JM,Smith MA,Moyé LA,Morgenstern LB

    更新日期:2004-08-10 00:00:00

  • Functional MRI mapping of occipital and frontal cortical activity during voluntary and imagined saccades.

    abstract::We investigated the activation of frontal and occipital cortical areas in 14 normal volunteers during voluntary saccades in light or dark and during imagined saccades using functional magnetic resonance imaging (FMRI) with electro-oculogram monitoring. Voluntary saccades in light or dark and imagined saccades led to a...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.49.2.416

    authors: Bodis-Wollner I,Bucher SF,Seelos KC,Paulus W,Reiser M,Oertel WH

    更新日期:1997-08-01 00:00:00

  • Macrostructural abnormalities in Korsakoff syndrome compared with uncomplicated alcoholism.

    abstract:OBJECTIVE:To distinguish, in patients with Korsakoff syndrome (KS), the structural brain abnormalities shared with alcoholic patients without KS (AL), from those specific to KS. METHODS:MRI data were collected in 11 alcoholic patients with KS, 34 alcoholic patients without KS, and 25 healthy control subjects (CS). Gra...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e318251834e

    authors: Pitel AL,Chételat G,Le Berre AP,Desgranges B,Eustache F,Beaunieux H

    更新日期:2012-04-24 00:00:00

  • Socioeconomic status and disability progression in multiple sclerosis: A multinational study.

    abstract:OBJECTIVE:To examine the association between socioeconomic status (SES) and disability outcomes and progression in multiple sclerosis (MS). METHODS:Health administrative and MS clinical data were linked for 2 cohorts of patients with MS in British Columbia (Canada) and South East Wales (UK). SES was measured at MS sym...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000007190

    authors: Harding KE,Wardle M,Carruthers R,Robertson N,Zhu F,Kingwell E,Tremlett H

    更新日期:2019-03-26 00:00:00

  • A preliminary MRI study of the geometry of brain displacement and level of consciousness with acute intracranial masses.

    abstract::We determined the horizontal and vertical components of brain displacement on coronal MRIs in 10 patients with acute supratentorial masses. The vertical distances from the superior sagittal sinus to the pontomesencephalic junction (PMJ) and from the vertical midline of the brain to the PMJ did not differ from measurem...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.39.5.622

    authors: Ropper AH

    更新日期:1989-05-01 00:00:00

  • EEG predicts surgical outcome in lesional frontal lobe epilepsy.

    abstract:BACKGROUND:Because of the relatively poor results of frontal lobe epilepsy (FLE) surgery, identification of prognostic factors for surgical outcome is of great importance. METHODS:To identify predictive factors for FLE surgery, we analyzed the data of 61 patients (mean age at surgery 19.2) who had undergone presurgica...

    journal_title:Neurology

    pub_type: 临床试验,杂志文章

    doi:10.1212/wnl.54.7.1470

    authors: Janszky J,Jokeit H,Schulz R,Hoppe M,Ebner A

    更新日期:2000-04-11 00:00:00

  • Incidence of contrast nephropathy from cerebral CT angiography and CT perfusion imaging.

    abstract::The incidence of contrast-induced nephropathy was examined in 1,075 patients receiving routine CT angiography and CT perfusion brain imaging at a single institution. Fifty-two patients had a creatinine rise of > or =0.5 mg/dL. In four patients (0.37%), the administration of IV contrast medium possibly contributed to r...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.WNL.0000161845.69114.62

    authors: Josephson SA,Dillon WP,Smith WS

    更新日期:2005-05-24 00:00:00

  • Longitudinal diffusion changes following postoperative delirium in older people without dementia.

    abstract:OBJECTIVE:To investigate the effect of postoperative delirium on longitudinal brain microstructural changes, as measured by diffusion tensor imaging. METHODS:We studied a subset of the larger Successful Aging after Elective Surgery (SAGES) study cohort of older adults (≥70 years) without dementia undergoing elective s...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000004329

    authors: Cavallari M,Dai W,Guttmann CRG,Meier DS,Ngo LH,Hshieh TT,Fong TG,Schmitt E,Press DZ,Travison TG,Marcantonio ER,Jones RN,Inouye SK,Alsop DC,SAGES Study Group.

    更新日期:2017-09-05 00:00:00

  • Regional cerebral glucose metabolism in dementia with Lewy bodies and Alzheimer's disease.

    abstract:OBJECTIVE:To delineate the features of regional cerebral metabolic rate of glucose (CMRglc) in dementia with Lewy bodies (DLB). METHODS:We compared absolute CMRglc in 12 patients with a clinical diagnosis of DLB, 12 patients with a clinical diagnosis of Alzheimer's disease (AD), and 12 normal volunteers (NC), using 18...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.51.1.125

    authors: Ishii K,Imamura T,Sasaki M,Yamaji S,Sakamoto S,Kitagaki H,Hashimoto M,Hirono N,Shimomura T,Mori E

    更新日期:1998-07-01 00:00:00

  • Parkinsonism in Ontario: increased mortality compared with controls in a large cohort study.

    abstract:BACKGROUND:PD was associated with increased mortality before levodopa therapy became available. There have been conflicting reports of PD mortality in the modern era. OBJECTIVE:To assess current mortality rates in a large unselected population receiving treatment for parkinsonism (PKM) followed for up to 6 years. MET...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.57.12.2278

    authors: Guttman M,Slaughter PM,Theriault ME,DeBoer DP,Naylor CD

    更新日期:2001-12-26 00:00:00

  • Gender differences in the incidence of AD and vascular dementia: The EURODEM Studies. EURODEM Incidence Research Group.

    abstract:OBJECTIVE:To study the difference in risk for dementing diseases between men and women. BACKGROUND:Previous studies suggest women have a higher risk for dementia than men. However, these studies include small sample sizes, particularly in the older age groups, when the incidence of dementia is highest. METHODS:Pooled...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.53.9.1992

    authors: Andersen K,Launer LJ,Dewey ME,Letenneur L,Ott A,Copeland JR,Dartigues JF,Kragh-Sorensen P,Baldereschi M,Brayne C,Lobo A,Martinez-Lage JM,Stijnen T,Hofman A

    更新日期:1999-12-10 00:00:00

  • Stem cell therapy in ischemic stroke: role of IV and intra-arterial therapy.

    abstract:OBJECTIVE:Cell-based therapies are being investigated as an adjunct to IV thrombolysis or mechanical thrombectomy in ischemic stroke. This review summarizes the potential applications as well as challenges of intravascular cell delivery in ischemic stroke. METHOD:We conducted a search of Medline as well as the clinica...

    journal_title:Neurology

    pub_type: 杂志文章,评审

    doi:10.1212/WNL.0b013e31826959d2

    authors: Misra V,Ritchie MM,Stone LL,Low WC,Janardhan V

    更新日期:2012-09-25 00:00:00

  • Pituitary enlargement in patients with intracranial hypotension syndrome.

    abstract::Article abstract-The authors analyzed whether the pituitary gland enlarges in intracranial hypotension syndrome by studying 11 consecutive patients. Initial MRI scans showed pituitary gland enlargement with a convex superior margin. Follow-up MRI studies revealed that the size of the gland invariably diminished in all...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.55.12.1895

    authors: Alvarez-Linera J,Escribano J,Benito-León J,Porta-Etessam J,Rovira A

    更新日期:2000-12-26 00:00:00

  • Diagnostic value of myotactic reflexes in axonal and demyelinating polyneuropathy.

    abstract::In 11 patients with chronic inflammatory demyelinating polyneuropathy (CIDP) and 11 patients with chronic idiopathic axonal polyneuropathy (CIAP), absent myotatic reflexes were significantly associated more often with CIDP than with CIAP, an absent biceps-reflex having the highest sensitivity and specificity for the d...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.53.7.1573

    authors: van Dijk GW,Wokke JH,Notermans NC,van Gijn J,Franssen H

    更新日期:1999-10-22 00:00:00

  • Increased risk of familial late-onset Alzheimer's disease in women.

    abstract::The role of gender in the pathogenesis of Alzheimer's disease (AD) is an important issue that remains controversial. We compared men and women in late-onset familial AD kindreds for the risk of developing AD by studying 26 well-characterized familial AD kindreds from the Oregon Alzheimer Disease Center and, for confir...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.46.1.126

    authors: Payami H,Montee K,Grimslid H,Shattuc S,Kaye J

    更新日期:1996-01-01 00:00:00

  • Simple partial seizures: clinicofunctional correlation--a case report.

    abstract::A 12-year-old girl developed simple partial motor and sensory seizures due to a right perirolandic astrocytoma. Subdural EEG recording and functional stimulation disclosed close correlation between EEG-clinical manifestations of focal seizures and functional responses to cortical stimulation. This case supports the id...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.42.3.642

    authors: Arroyo S,Krauss GL,Lesser RP,Gordon B,Hart J Jr,Carson BS,Uematsu S

    更新日期:1992-03-01 00:00:00

  • A prospective study of predictors of poststroke depression.

    abstract:OBJECTIVE:To investigate the association between early depressive behavior after stroke onset and occurrence of poststroke depression (PSD) at 3- and 12-month follow-up evaluations. METHODS:The study prospectively included 273 patients with first-ever single uncomplicated ischemic stroke. In the stroke unit, nurses sc...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.WNL.0000150935.05940.2D

    authors: Carota A,Berney A,Aybek S,Iaria G,Staub F,Ghika-Schmid F,Annable L,Guex P,Bogousslavsky J

    更新日期:2005-02-08 00:00:00

  • Increased risk of stroke in patients with chronic kidney disease after recurrent hypoglycemia.

    abstract:OBJECTIVE:In this study, we aimed to investigate the effect of hypoglycemia on cardiovascular outcomes in a sample of patients with chronic kidney disease (CKD). METHODS:Information about study participants was extracted from the National Health Insurance Research Database of Taiwan for the years 1998 through 2008. We...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000000711

    authors: Yu TM,Lin CL,Chang SN,Sung FC,Kao CH

    更新日期:2014-08-19 00:00:00

  • Cortical dysplasia with angiodysgenesis and chronic inflammation in multifocal partial epilepsy.

    abstract::A 25-year-old man with a long history of temporal lobe epilepsy developed right occipital lobe seizures and a progressive right homonymous hemianopia. MRI showed diffuse enhancement of the left temporoparieto-occipital white matter and cortical thickening of the left medial temporal lobe. The resected temporal lobe re...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.52.3.654

    authors: Thom M,Moran NF,Plant GT,Stevens JM,Scaravilli F

    更新日期:1999-02-01 00:00:00

  • Broca's area aphasias: aphasia after lesions including the frontal operculum.

    abstract::We report 9 cases of aphasia following lesions in the region of the left frontal operculum. It is not possible to capture their variety of clinical manifestations with the simple labels of "Broca's area aphasia." or "Broca's area aphasia." Analysis of the breakdown of various components of speech and language in these...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.40.2.353

    authors: Alexander MP,Naeser MA,Palumbo C

    更新日期:1990-02-01 00:00:00

  • Avoidance of dyskinesia: preclinical evidence for continuous dopaminergic stimulation.

    abstract::Current concepts suggest that avoidance of pulsatile stimulation of dopamine receptors in Parkinson's disease (PD) can prevent the onset of dyskinesia. In MPTP-treated primates, repeated administration of levodopa or other short-acting dopamine agonist drugs leads to the onset of marked involuntary movements. In contr...

    journal_title:Neurology

    pub_type: 杂志文章,评审

    doi:10.1212/wnl.62.1_suppl_1.s47

    authors: Jenner P

    更新日期:2004-01-13 00:00:00