Abstract:
:The Israeli Teratogen Information Service prospectively followed up 210 pregnancies with first trimester carbamazepine exposure. Pregnancy outcome was compared with that of two overlapping controls, matched and general (n = 629), exposed to nonteratogenic agents. Our study suggests a twofold increase in the rate of major congenital anomalies (12/160 [carbamazepine] versus 18/560 [general control]; relative risk 2.24; 95% CI 1.1-4.56) and a birth weight reduction of approximately 250 g after in utero exposure to carbamazepine.
journal_name
Neurologyjournal_title
Neurologyauthors
Diav-Citrin O,Shechtman S,Arnon J,Ornoy Adoi
10.1212/wnl.57.2.321subject
Has Abstractpub_date
2001-07-24 00:00:00pages
321-4issue
2eissn
0028-3878issn
1526-632Xjournal_volume
57pub_type
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