Abstract:
:To determine whether the complete correction of hyperglycemia of diabetes can rapidly improve abnormal peripheral nerve function, eight hyperglycemic insulin-requiring diabetics underwent 3 days of glucose control with an artificial endocrine pancreas, the BIOSTATOR Glucose Controller. Comparison of neurologic assessment before and after BIOSTATOR treatment showed improvement only in ulnar sensory conduction velocity (+ 3.2 +/- 1.4 meters per second, p less than 0.032) and no significant changes in 24 other nerve conduction measurements, computer-assisted examination, and scored neurologic assessment. Any significant beneficial effect on nerve function resulting from correction of hyperglycemia probably requires more than 3 days to be manifested.
journal_name
Neurologyjournal_title
Neurologyauthors
Service FJ,Daube JR,O'Brien PC,Dyck PJdoi
10.1212/wnl.31.11.1375subject
Has Abstractpub_date
1981-11-01 00:00:00pages
1375-80issue
11eissn
0028-3878issn
1526-632Xjournal_volume
31pub_type
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