Insulin resistance and risk for stroke.

abstract：:Since the emergence of the specialty, neurologists have worked with a rather restricted list of relatively inexpensive pharmacologic agents. This is rapidly changing with the development of new agents for the treatment of migraine, multiple sclerosis, Parkinson's disease, Alzheimer's disease, and epilepsy, accelerated...

journal_title：Neurology

authors： Gunderson CH

更新日期：1995-03-01 00:00:00

abstract：OBJECTIVE:To estimate rates, predictors, and prognostic importance of recanalization in an unselected series of patients with stroke treated with IV thrombolysis. METHODS:We performed a CT angiography or transcranial Doppler (TCD) follow-up examination 24 hours after IV thrombolysis in 64 patients with documented occl...

journal_title：Neurology

authors： Zangerle A,Kiechl S,Spiegel M,Furtner M,Knoflach M,Werner P,Mair A,Wille G,Schmidauer C,Gautsch K,Gotwald T,Felber S,Poewe W,Willeit J

更新日期：2007-01-02 00:00:00

abstract：OBJECTIVE:To investigate the clinical profile of rofecoxib, a long-acting (approximately 17-hour half-life) selective cyclo-oxygenase-2 inhibitor, for the acute treatment of migraine. METHODS:A randomized, double-blind, placebo-controlled, parallel-group study was conducted. Patients age > or =18 treated a moderate or...

journal_title：Neurology

authors： Silberstein S,Tepper S,Brandes J,Diamond M,Goldstein J,Winner P,Venkatraman S,Vrijens F,Malbecq W,Lines C,Visser WH,Reines S,Yuen E

更新日期：2004-05-11 00:00:00

abstract：OBJECTIVE:To evaluate the presence of prodromal markers of Parkinson disease (PD) in patients with longstanding idiopathic REM sleep behavior disorder (IRBD), a small subgroup of individuals with IRBD with long-term follow-up thought not to be at risk of developing PD. METHODS:Demographic, clinical, and neuroimaging m...

journal_title：Neurology

authors： Iranzo A,Stefani A,Serradell M,Martí MJ,Lomeña F,Mahlknecht P,Stockner H,Gaig C,Fernández-Arcos A,Poewe W,Tolosa E,Högl B,Santamaria J,SINBAR (Sleep Innsbruck Barcelona) group.

更新日期：2017-07-18 00:00:00

abstract：OBJECTIVE:To investigate whether recurrent seizures cause hippocampal damage in temporal lobe epilepsy (TLE). PATIENTS:Eighteen patients with newly diagnosed cryptogenic TLE, 14 patients with chronic well-controlled cryptogenic TLE, 32 patients with chronic drug-resistant cryptogenic TLE, and 25 healthy subjects were ...

journal_title：Neurology

authors： Kälviäinen R,Salmenperä T,Partanen K,Vainio P,Riekkinen P,Pitkänen A

更新日期：1998-05-01 00:00:00

abstract：:Current medical educational theory encourages the development of competency-based curricula. The Accreditation Council for Graduate Medical Education's 6 core competencies for resident education (medical knowledge, patient care, professionalism, interpersonal and communication skills, practice-based learning, and syst...

journal_title：Neurology

authors： Merlin LR,Horak HA,Milligan TA,Kraakevik JA,Ali II

更新日期：2014-07-29 00:00:00

abstract：:The association of APOE genotypes with cerebral microbleeds (CMBs) was examined on the basis of the location of CMBs in 414 patients who were admitted primarily because of stroke. With respect to possession of the epsilon2 or epsilon4 allele, the adjusted odds ratio was 1.94 (1.05 to 3.58) for lobar CMBs but 1.21 (0.6...

journal_title：Neurology

authors： Kim M,Bae HJ,Lee J,Kang L,Lee S,Kim S,Lee JE,Lee KM,Yoon BW,Kwon O,Koo JS,Kim BK

更新日期：2005-11-08 00:00:00

abstract：OBJECTIVE:This study aimed to determine the frequency of CNS infection by dengue virus (DENV) in individuals with fatal outcomes. METHODS:Samples of 150 individuals suspect of an infection disease and with fatal outcomes were investigated for evidence of the presence of DENV. The sampling was made up of 150 CSF, 120 t...

journal_title：Neurology

authors： Araújo FM,Araújo MS,Nogueira RM,Brilhante RS,Oliveira DN,Rocha MF,Cordeiro RA,Araújo RM,Sidrim JJ

更新日期：2012-03-06 00:00:00

abstract：:Migraine, especially migraine with aura (MA), is an established risk factor for ischemic lesions of the brain. Recent evidence has also linked migraine to a broader range of ischemic vascular disorders including angina, myocardial infarction, coronary revascularization, claudication, and cardiovascular mortality. The ...

journal_title：Neurology

authors： Bigal ME,Kurth T,Hu H,Santanello N,Lipton RB

更新日期：2009-05-26 00:00:00

abstract：OBJECTIVE:To test the hypothesis that patients with multiple sclerosis (MS) with intereye asymmetry on low contrast letter acuity, and thickness of the retinal nerve fiber layer (RNFL), would exhibit corresponding changes in cortical timing and amplitude responses on pattern reversal multifocal visual evoked potentials...

journal_title：Neurology

authors： Frohman AR,Schnurman Z,Conger A,Conger D,Beh S,Greenberg B,Sutter E,Calabresi PA,Balcer LJ,Frohman TC,Frohman EM

更新日期：2012-08-21 00:00:00

abstract：OBJECTIVE:To perform a systematic review and meta-analysis of studies reporting recurrent intracranial hemorrhage (ICH) and ischemic stroke (IS) in ICH survivors with atrial fibrillation (AF) during long-term follow-up. METHODS:A comprehensive literature search including MEDLINE, EMBASE, Cochrane library, clinical tri...

journal_title：Neurology

authors： Korompoki E,Filippidis FT,Nielsen PB,Del Giudice A,Lip GYH,Kuramatsu JB,Huttner HB,Fang J,Schulman S,Martí-Fàbregas J,Gathier CS,Viswanathan A,Biffi A,Poli D,Weimar C,Malzahn U,Heuschmann P,Veltkamp R

更新日期：2017-08-15 00:00:00

abstract：BACKGROUND:The histopathology of AIDS-associated myelopathy (AM) closely resembles that of myelopathies due to cobalamin or folate deficiency, with white matter vacuolization in the spinal cord. The pathogenesis of AM appears unrelated to direct HIV infection of the spinal cord. There is abnormal trans-methylation meta...

journal_title：Neurology

authors： Di Rocco A,Werner P,Bottiglieri T,Godbold J,Liu M,Tagliati M,Scarano A,Simpson D

更新日期：2004-10-12 00:00:00

abstract：:Reflex sympathetic dystrophy (RSD) is a relatively common disabling disorder of unknown pathophysiology. From a cohort of 52 patients, carefully selected to fulfill the recently formulated diagnostic criteria for RSD, venous blood samples were taken for typing of class I and II major histocompatibility antigens. The f...

journal_title：Neurology

authors： Kemler MA,van de Vusse AC,van den Berg-Loonen EM,Barendse GA,van Kleef M,Weber WE

更新日期：1999-10-12 00:00:00

abstract：:The authors found serum immunoglobulin M (IgM) autoantibody in a patient with typical acute cerebellar ataxia (ACA) and identified the antigen molecule as triosephosphate isomerase (TPI). TPI antigenicity to the patient's antibody was the highest in the cerebellar tissue. Eight of 23 patients with ACA had increased Ig...

journal_title：Neurology

authors： Uchibori A,Sakuta M,Kusunoki S,Chiba A

更新日期：2005-10-11 00:00:00

abstract：BACKGROUND:Mutations in the early growth response 2 (EGR2) gene have recently been found in patients with congenital hypomyelinating neuropathy and Charcot-Marie-Tooth type 1 (CMT1) disease. OBJECTIVE:To determine the frequency of EGR2 mutations in patients with a diagnosis of CMT1, Dejerine-Sottas syndrome (DSS), or ...

journal_title：Neurology

authors： Timmerman V,De Jonghe P,Ceuterick C,De Vriendt E,Löfgren A,Nelis E,Warner LE,Lupski JR,Martin JJ,Van Broeckhoven C

更新日期：1999-06-10 00:00:00

abstract：BACKGROUND:Cerebral microbleeds (CMB) may be indicative of a hemorrhage-prone microangiopathy. OBJECTIVE:To determine if increased numbers of these lesions are predictive of intracerebral hemorrhage (ICH), especially in terms of a distributional association. METHODS:The authors examined consecutively 227 patients wit...

journal_title：Neurology

authors： Lee SH,Bae HJ,Kwon SJ,Kim H,Kim YH,Yoon BW,Roh JK

更新日期：2004-01-13 00:00:00

abstract：:We made phenotypic analysis of 14 families with spinal muscular atrophy (SMA) linking to chromosome 5q11.2-13.3 (SMA 5q), and 2 that may not map to this locus, to assess clinical symptoms among SMA families known to result from mutation at the identical gene/locus. Although the current number of families is still smal...

journal_title：Neurology

authors： Munsat TL,Skerry L,Korf B,Pober B,Schapira Y,Gascon GG,al-Rajeh SM,Dubowitz V,Davies K,Brzustowicz LM

更新日期：1990-12-01 00:00:00

abstract：:Central nervous system involvement in melioidosis is unusual. We describe a 34-year-old man who developed a Pseudomonas pseudomallei meningitis, manifested as bilateral third-nerve palsies, 13 years after having been in southeast Asia. Diagnosis was established by a fourfold rise in the serum antibody titer for the ba...

journal_title：Neurology

authors： Beck RW,Janssen RS,Smiley ML,Schatz NJ,Savino PJ,Rubin DH

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:To compare characteristics between Black and White patients with amyotrophic lateral sclerosis (ALS) in order to identify disparities and phenotypic variability. METHODS:We performed database review for patients seen between 1997 and 2020 at the Emory ALS Center in Atlanta, Georgia. Patients with ALS were in...

journal_title：Neurology

authors： Brand D,Polak M,Glass JD,Fournier CN

更新日期：2020-12-28 00:00:00

abstract：:Although the ultimate diagnosis of multiple sclerosis (MS) still remains clinical, confirmatory laboratory aids can be of marked assistance, especially in early and atypical cases. Whereas numerous tests have been described, the only ones to withstand scrutiny in numerous laboratories have been various immunoglobulin ...

journal_title：Neurology

authors： Johnson KP

更新日期：1980-07-01 00:00:00

abstract：OBJECTIVE:To test the accuracy of an equation in adult patients with status epilepticus that calculates the free concentration of serum valproic acid (fVPA) from the total concentration of serum valproic acid (tVPA) and serum albumin. METHODS:All adult patients with status epilepticus who were treated at a Swiss acade...

journal_title：Neurology

authors： Fisch U,Baumann SM,Semmlack S,Marsch S,Rüegg S,Sutter R

更新日期：2021-01-05 00:00:00

abstract：:The association between migraine and cervical artery dissection (CAD) was explored in a hospital-based case-control study. Migraine was present in 49.1% (23/47) of patients with CAD and in 21% (11/52) of patients hospitalized for a cerebral ischemic event not related to a CAD (adjusted odds ratio = 3.6; 1.5 to 8.6, p ...

journal_title：Neurology

authors： Tzourio C,Benslamia L,Guillon B,Aïdi S,Bertrand M,Berthet K,Bousser MG

更新日期：2002-08-13 00:00:00

abstract：OBJECTIVE:To evaluate interictal, circulating sphingolipids in women migraineurs. METHODS:In the fasting state, serum samples were obtained pain-free from 88 women with episodic migraine (EM; n=52) and from controls (n=36). Sphingolipids were detected and quantified by high-performance liquid chromatography coupled wi...

journal_title：Neurology

authors： Peterlin BL,Mielke MM,Dickens AM,Chatterjee S,Dash P,Alexander G,Vieira RV,Bandaru VV,Dorskind JM,Tietjen GE,Haughey NH

更新日期：2015-10-06 00:00:00

abstract：OBJECTIVE:To compare the accuracy of Alberta Stroke Program Early Computed Tomography Score (ASPECTS) and CT perfusion to detect established infarction in acute anterior circulation stroke. METHODS:We performed an observational study in 59 acute anterior circulation ischemic stroke patients who underwent brain noncont...

journal_title：Neurology

authors： Demeestere J,Garcia-Esperon C,Garcia-Bermejo P,Ombelet F,McElduff P,Bivard A,Parsons M,Levi C

更新日期：2017-06-13 00:00:00

abstract：OBJECTIVE:To perform an evidence-based review of the safety and efficacy of botulinum neurotoxin (BoNT) in the treatment of movement disorders. METHODS:A literature search was performed including MEDLINE and Current Contents for therapeutic articles relevant to BoNT and selected movement disorders. Authors reviewed, a...

journal_title：Neurology

authors： Simpson DM,Blitzer A,Brashear A,Comella C,Dubinsky R,Hallett M,Jankovic J,Karp B,Ludlow CL,Miyasaki JM,Naumann M,So Y,Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology.

更新日期：2008-05-06 00:00:00

abstract：:Information about 255 children and adults with Pompe disease was gathered through a questionnaire. Disease severity was associated with disease duration and not with age; an early manifestation of the disease implied earlier wheelchair or ventilator dependency. The patient group under age 15 included a subgroup with a...

journal_title：Neurology

authors： Hagemans ML,Winkel LP,Hop WC,Reuser AJ,Van Doorn PA,Van der Ploeg AT

更新日期：2005-06-28 00:00:00

abstract：OBJECTIVE:To evaluate the utility of "clinic room" case presentation in the ambulatory care setting. BACKGROUND:Neurology is increasingly an outpatient specialty. The transition from ward to clinic presents challenges for student and resident education. Interaction between attending physician and trainee is limited by...

journal_title：Neurology

authors： Smith AG,Bromberg MB,Singleton JR,Forshew DA

更新日期：1999-01-15 00:00:00

abstract：OBJECTIVE:To classify neuropathologic alterations in the brains of nondemented older adults using current sets of criteria for AD. BACKGROUND:AD neuropathologic alterations are found in the brains of some nondemented elderly subjects and suggest the possibility of presymptomatic AD. Three sets of guidelines have been ...

journal_title：Neurology

authors： Schmitt FA,Davis DG,Wekstein DR,Smith CD,Ashford JW,Markesbery WR

更新日期：2000-08-08 00:00:00

abstract：:We treated 36 patients with motor fluctuations and dyskinesias on chronic levodopa therapy with cabergoline (CBG) once a day for a mean period of 14.2 +/- 5.8 months. There was a significant increase in the "on" hours and a reduction in "off-period" dystonia. Ten patients continued to show a marked improvement after 2...

journal_title：Neurology

authors： Lera G,Vaamonde J,Rodriguez M,Obeso JA

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:The major histocompatibility complex (MHC) has been consistently associated with susceptibility to MS and the course of several other human autoimmune diseases. A putative association between the course and severity of MS and the MHC remains controversial. METHODS:DR and DQ genotyping by either restriction ...

journal_title：Neurology

authors： Weinshenker BG,Santrach P,Bissonet AS,McDonnell SK,Schaid D,Moore SB,Rodriguez M

更新日期：1998-09-01 00:00:00