Abstract:
:Central nervous system involvement in melioidosis is unusual. We describe a 34-year-old man who developed a Pseudomonas pseudomallei meningitis, manifested as bilateral third-nerve palsies, 13 years after having been in southeast Asia. Diagnosis was established by a fourfold rise in the serum antibody titer for the bacterium. Recovery occurred after treatment with rifampin, isoniazid hydrochloride, ethambutol, and trimethoprim-sulfamethoxazole. Since a long latent period from exposure to overt infection is possible, additional cases of melioidosis in the United States can still be expected in veterans of the Vietnam War.
journal_name
Neurologyjournal_title
Neurologyauthors
Beck RW,Janssen RS,Smiley ML,Schatz NJ,Savino PJ,Rubin DHdoi
10.1212/wnl.34.1.105subject
Has Abstractpub_date
1984-01-01 00:00:00pages
105-7issue
1eissn
0028-3878issn
1526-632Xjournal_volume
34pub_type
杂志文章相关文献
NEUROLOGY文献大全abstract::The role of genetic factors in determining risk for status epilepticus (SE) was examined in twins identified using the population-based Virginia Twin Registry. Concordance rates for SE were 0.38 for monozygotic (MZ) and 0.00 for dizygotic (DZ) twins, with the rate in MZs being significantly increased over DZs. The pre...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.50.2.558
更新日期:1998-02-01 00:00:00
abstract::Cognitive impairment is a frequent manifestation of advanced human immunodeficiency virus (HIV) infection. The response to antiretroviral medication is often partial and poorly sustained. Recent studies suggest that free radical production within the CNS and neuronal apoptosis may play important roles in the pathogene...
journal_title:Neurology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1212/wnl.50.3.645
更新日期:1998-03-01 00:00:00
abstract:OBJECTIVE:To review the disciplinary process by which the American Academy of Neurology (AAN) enforces its formalized standards of professional conduct. METHODS:We reviewed the AAN's Disciplinary Action Policy. We tracked the elapsed time from receipt to final decision of all allegations ("complaints") of improper con...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e318202014e
更新日期:2010-12-14 00:00:00
abstract:OBJECTIVE:It is known that muscle phosphorylase deficiency restricts carbohydrate utilization, but the implications for muscle fat metabolism have not been studied. We questioned whether patients with McArdle disease can compensate for the blocked muscle glycogen breakdown by enhancing fat oxidation during exercise. M...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000343002.74480.e4
更新日期:2009-02-24 00:00:00
abstract:OBJECTIVE:To compare effects of immediate-release (IR) and sustained-release (CR) carbidopa/levodopa in levodopa-naive PD patients. BACKGROUND:It was hypothesized that the long-acting preparation would be associated with fewer long-term complications. METHODS:A total of 618 patients were studied in 36 centers worldwi...
journal_title:Neurology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1212/wnl.53.5.1012
更新日期:1999-09-22 00:00:00
abstract::We reviewed the outcome (developmental, neurologic, and seizure) and prognostic factors of 57 cases of infantile spasms (17 cryptogenic, 40 symptomatic). The mean developmental score of the cryptogenic group (71.2 +/- 24.2) was significantly higher than that of the symptomatic group (48.4 +/- 24.5), as assessed by the...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.43.11.2322
更新日期:1993-11-01 00:00:00
abstract::The authors evaluated education attainment and neuropsychological deficits in children with sickle cell disease (SCD) and silent cerebral infarcts. Children with silent infarcts had twice the rate of school difficulties as children without infarcts. Eighty percent of silent infarct cases had clinically significant cog...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.56.8.1109
更新日期:2001-04-24 00:00:00
abstract::A neurocutaneous syndrome is described in which spastic paraplegia, peroneal neuropathy, and crural hypopigmentation are inherited in a dominant pattern. Spastic paraplegia becomes clinically apparent during adolescence or in childhood and progresses slowly throughout the adult years with a variability in severity of ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.31.6.754
更新日期:1981-06-01 00:00:00
abstract::When the WHO's Topic Advisory Group for Neurology (TAG) started work on revision of the ICD-10 diagnostic codes in June 2009, the issues were daunting. The existing classification was produced a generation ago and the need to move to the digital age was becoming imperative. Appreciating modern advances in genetics and...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e31829a333c
更新日期:2013-07-09 00:00:00
abstract::The authors investigated the PRNP Met129Val polymorphism in 1,393 subjects including 482 patients with Alzheimer disease (AD) and two independent control groups. In patients, PRNP Met homozygosity conferred increasing risk with decreasing age at onset (onset: 61 to 70 years, n = 151, p = 0.02, odds ratio [OR] = 1.72, ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000130198.72589.69
更新日期:2004-07-27 00:00:00
abstract::Migraine shows strong familial aggregation. However, the number of genes involved in the disorder is unknown and not identified. Nitric oxide is involved in the central processing of pain stimuli and plays an important role in the regulation of basal or stimulated vasodilation. Nitric oxide synthase, which controls th...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.49.2.614
更新日期:1997-08-01 00:00:00
abstract::The authors studied immunoglobulin G (IgG) Fc receptor (FcgammaR) IIA, IIIA, and IIIB polymorphisms in 62 patients with Guillain-Barré syndrome (GBS) and in 89 healthy controls. The FcgammaR genotypes and allele frequencies did not differ significantly between the patients with GBS and the controls. Patients homozygou...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.55.5.705
更新日期:2000-09-12 00:00:00
abstract::Of 58 consecutive patients with spontaneous CSF leaks, nine exhibited features of connective tissue disorder. One had Marfan's syndrome. Five additional patients had hyperflexible joints, of whom four had arachnodactyly, four were tall and slender, two had hyperextensible skin, and one had a strong family history of a...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.58.5.814
更新日期:2002-03-12 00:00:00
abstract::Twenty-two patients were analyzed 2 or more years after corpus callosum section (9 partial, 13 total). Forty-one percent had class 1 outcome (elimination of secondarily generalized and complex partial seizures), 32% had class 2 outcome (elimination of secondarily generalized seizures), and 27% had class 3 outcome (no ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.38.1.19
更新日期:1988-01-01 00:00:00
abstract::Men and women with dementia of the Alzheimer type (DAT) had more brain atrophy and ventricular dilatation, measured by quantitative CT, than did respective age- and sex-matched healthy controls (p less than 0.05). The male DAT patients with mild dementia had a larger mean third ventricle volume, whereas male patients ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.36.12.1563
更新日期:1986-12-01 00:00:00
abstract::The incidence of new-onset epilepsy is higher among the elderly, the most rapidly growing segment of the population, than in any other age group. New-onset seizures in elderly patients are typically cryptogenic or symptomatic partial seizures that require long-term treatment. Because seizures in the elderly are often ...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/wnl.63.10_suppl_4.s40
更新日期:2004-11-23 00:00:00
abstract::The authors report an unusual case of venous infarction of the spinal cord associated with endoscopic sclerotherapy for esophageal varices. MR imaging findings included signal abnormalities and abnormal enhancement of the affected spinal cord and T-8 vertebral body. A review of the hemodynamic changes associated with ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.47.4.1081
更新日期:1996-10-01 00:00:00
abstract::We analyzed the frequency of cardiac embolic sources in 62 patients with acute lacunar stroke vs 50 controls. In post hoc analysis, 11 patients with lacunar stroke having neither hypertension nor diabetes mellitus (non-HDM group) had a higher frequency of right-to-left shunt (RLS) (82%) than patients with risk factors...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000253197.83777.c7
更新日期:2007-02-13 00:00:00
abstract::[Methyl-3H]epsilon-N-trimethyl-L-lysine was administered to patients with primary systemic carnitine deficiency and to controls. In both groups, labeled carnitine appeared in blood and urine within 2 hours, and the specific radioactivity of urinary carnitine peaked between 2 and 6 hours. The specific radioactivity of ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.31.7.813
更新日期:1981-07-01 00:00:00
abstract:BACKGROUND:Although phenylketonuria is a treatable disease, patients with late or nonoptimal phenylalanine-restricted diet may experience brain damage. The authors used tridimensional MRI and a voxelwise analysis method to investigate possible volume changes in the brain parenchyma of patients with phenylketonuria. ME...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000204415.39853.4a
更新日期:2006-04-11 00:00:00
abstract:BACKGROUND:Several studies indicate semantic fluency more sensitively discriminates patients with Alzheimer disease (AD) from normal elderly persons, with disproportionate impairment of semantic over phonemic fluency. OBJECTIVE:To determine the ability of abbreviated fluency measures in the clinic setting (1-minute le...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.62.4.556
更新日期:2004-02-24 00:00:00
abstract:OBJECTIVE:Small uncontrolled series suggest that treatment of obstructive sleep apnea (OSA) in patients with epilepsy may improve seizure control. Prior to conducting a definitive randomized controlled trial, we addressed critical design issues in a pilot study. METHODS:We identified a cohort of adult patients with me...
journal_title:Neurology
pub_type: 杂志文章,随机对照试验
doi:10.1212/01.wnl.0000323927.13250.54
更新日期:2008-08-19 00:00:00
abstract::We report two conjugal cases of amyotrophic lateral sclerosis (ALS) occurring between 1977 and 1991 in southern France (Languedoc-Roussillon). Although conjugal ALS may occur by chance, the description of two cases in the same area points to a role of environmental or genetic factors in the etiology of the disease. ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.44.3_part_1.547
更新日期:1994-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the frequency and types of change in "self" seen in frontotemporal dementia (FTD) and to determine the relative involvement of the nondominant and dominant frontal and temporal brain regions in FTD patients with or without changes in a sense of self using neuropsychology tests and neuroimaging. B...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.57.5.817
更新日期:2001-09-11 00:00:00
abstract::The authors examined the neural function of a postmeningitic deaf-blind patient who regained his hearing with a multichannel cochlear implant. Auditory stimuli activated the temporal cortices of both sides in a manner similar to that of controls, reflecting the successful recruitment of the auditory cortex after impla...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000234141.72891.13
更新日期:2006-09-12 00:00:00
abstract::A patient with thymoma-associated neuromyotonia and voltage-gated potassium channel (Kv1.2 and Kv1.6) antibodies by immunoprecipitation and rat brain immunolabeling was treated successfully with immunoadsorption and cyclophosphamide. Curiously, glutamic acid decarboxylase antibodies, absent at onset, appeared later. S...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.WNL.0000156945.39471.2C
更新日期:2005-04-12 00:00:00
abstract:OBJECTIVE:This study was conducted to determine the relationship of frontal lobe cortical thickness and basal ganglia volumes to measures of cognition in adults with sickle cell anemia (SCA). METHODS:Participants included 120 adults with SCA with no history of neurologic dysfunction and 33 healthy controls (HCs). Part...
journal_title:Neurology
pub_type: 杂志文章,多中心研究
doi:10.1212/WNL.0000000000000188
更新日期:2014-03-11 00:00:00
abstract::The majority of patients with traumatic brain injury (TBI) are classified as having a mild TBI. Despite being categorized as mild, these individuals report ongoing and complex symptoms, which negatively affect their ability to complete activities of daily living and overall quality of life. Some of the major symptoms ...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/WNL.0000000000010830
更新日期:2020-11-03 00:00:00
abstract:OBJECTIVE:To examine the relationship of migraine and other severe headaches with panic disorder. METHODS:Representative samples of persons with migraine, non-migrainous severe headaches, and controls with no history of severe headaches, identified by a telephone survey, were interviewed in person, using a standardize...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.56.3.350
更新日期:2001-02-13 00:00:00
abstract:OBJECTIVE:To test the hypothesis that patients with multiple sclerosis (MS) with intereye asymmetry on low contrast letter acuity, and thickness of the retinal nerve fiber layer (RNFL), would exhibit corresponding changes in cortical timing and amplitude responses on pattern reversal multifocal visual evoked potentials...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e3182661edc
更新日期:2012-08-21 00:00:00