Abstract:
:Of 53 patients with drug-induced seizures seen in the last decade, 45% had single seizures, 40% had multiple convulsions, and 15% had status epilepticus. Generalized seizures with focal features were common, but simple partial (motor) seizures occurred in only two patients. Isoniazid, insulin, lidocaine, and psychotropic medications were the most common drugs that caused seizures. Forty-nine patients recovered without ill effects, but 4 patients died of cardiovascular complications. The combined cardiovascular toxicity of the convulsants, antidotes, and anticonvulsants was more important than the number or duration of seizures in determining outcome.
journal_name
Neurologyjournal_title
Neurologyauthors
Messing RO,Closson RG,Simon RPdoi
10.1212/wnl.34.12.1582subject
Has Abstractpub_date
1984-12-01 00:00:00pages
1582-6issue
12eissn
0028-3878issn
1526-632Xjournal_volume
34pub_type
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