Etiology of aseptic meningitis and encephalitis in an adult population.

abstract：OBJECTIVE:To estimate rates, predictors, and prognostic importance of recanalization in an unselected series of patients with stroke treated with IV thrombolysis. METHODS:We performed a CT angiography or transcranial Doppler (TCD) follow-up examination 24 hours after IV thrombolysis in 64 patients with documented occl...

journal_title：Neurology

authors： Zangerle A,Kiechl S,Spiegel M,Furtner M,Knoflach M,Werner P,Mair A,Wille G,Schmidauer C,Gautsch K,Gotwald T,Felber S,Poewe W,Willeit J

更新日期：2007-01-02 00:00:00

abstract：BACKGROUND:There is no generally accepted instrument for measuring quality of life (QOL) in patients with ALS. Current instruments are either too heavily weighted toward strength and physical function or useful for the evaluation of individuals but of less utility in assessing large samples. OBJECTIVE:To develop and e...

journal_title：Neurology

authors： Simmons Z,Felgoise SH,Bremer BA,Walsh SM,Hufford DJ,Bromberg MB,David W,Forshew DA,Heiman-Patterson TD,Lai EC,McCluskey L

更新日期：2006-11-14 00:00:00

abstract：OBJECTIVE:The objective of the present work is to examine images of the brain dissection by Flemish-born anatomist Andreas Vesalius (1514-1564) as originally represented in the Fabrica (1543), and later copied without Vesalius' permission by Spanish anatomist Juan Valverde de Hamusco (c1525-c1587) in Historia de la com...

journal_title：Neurology

authors： Lanska DJ,Lanska JR

更新日期：2013-02-26 00:00:00

abstract：BACKGROUND:Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with complicated pathogenesis that poses challenges with respect to diagnosis and monitoring of disease progression. OBJECTIVES:To identify a biomarker panel that elucidates ALS disease pathogenesis, distinguishes patients with A...

journal_title：Neurology

authors： Mitchell RM,Freeman WM,Randazzo WT,Stephens HE,Beard JL,Simmons Z,Connor JR

更新日期：2009-01-06 00:00:00

abstract：OBJECTIVE:We aimed to perform an observational study of age at loss of independent ambulation (LoA) and side-effect profiles associated with different glucocorticoid corticosteroid (GC) regimens in Duchenne muscular dystrophy (DMD). METHODS:We studied 340 participants in the Cooperative International Neuromuscular Res...

journal_title：Neurology

authors： Bello L,Gordish-Dressman H,Morgenroth LP,Henricson EK,Duong T,Hoffman EP,Cnaan A,McDonald CM,CINRG Investigators.

更新日期：2015-09-22 00:00:00

abstract：:The authors report the neuropathologic findings in a case of Sneddon's syndrome. There were multiple small, predominantly cortical, infarcts, with focal hyperplasia and fibrotic occlusion of arterial vessels in the superficial white matter, cortex, and leptomeninges. A very occasional arterial thrombus was seen. These...

journal_title：Neurology

authors： Hilton DA,Footitt D

更新日期：2003-04-08 00:00:00

abstract：:We measured the cerebral metabolic rate for glucose (CMRglc) with positron emission tomography and [18F]2-fluoro-2-deoxy-D-glucose in a 47-year-old man with trisomy 21 Down's syndrome (DS) and autopsy-confirmed Alzheimer's disease. Dementia was evident from a confirmed history of cognitive decline, memory loss, and pe...

journal_title：Neurology

authors： Schapiro MB,Ball MJ,Grady CL,Haxby JV,Kaye JA,Rapoport SI

更新日期：1988-06-01 00:00:00

abstract：:Despite strong evidence of the importance of hereditary factors in the etiology of Tourette's syndrome (TS), research findings have consistently pointed to a role of environmental influences. A recent line of research has suggested that tic disorders and associated behavioral disturbances, such as obsessive-compulsive...

journal_title：Neurology

authors： Kurlan R

更新日期：1998-06-01 00:00:00

abstract：:A 25-year-old man with a long history of temporal lobe epilepsy developed right occipital lobe seizures and a progressive right homonymous hemianopia. MRI showed diffuse enhancement of the left temporoparieto-occipital white matter and cortical thickening of the left medial temporal lobe. The resected temporal lobe re...

journal_title：Neurology

authors： Thom M,Moran NF,Plant GT,Stevens JM,Scaravilli F

更新日期：1999-02-01 00:00:00

abstract：:Among 50 patients with phenytoin intoxication, 14 had seizures during the episode. Seizures in 9 of these 14 patients probably resulted from poor seizure control despite high phenytoin levels, but in 5 cases, attacks were attributed to phenytoin toxicity. The only factor that seemed to correlate with seizures was a se...

journal_title：Neurology

authors： Stilman N,Masdeu JC

更新日期：1985-12-01 00:00:00

abstract：:We investigated the prevalence of Parkinson's disease and other types of parkinsonism in a Sicilian population using a door-to-door two-phase approach. This design called for the administration of a brief screening instrument to all subjects who, on November 1, 1987, were residents of Terrasini (Palermo Province), San...

journal_title：Neurology

authors： Morgante L,Rocca WA,Di Rosa AE,De Domenico P,Grigoletto F,Meneghini F,Reggio A,Savettieri G,Castiglione MG,Patti F

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVE:To assess if multifocal motor neuropathy (MMN) with and MMN without conduction block (CB) are similar or distinct diseases. METHODS:The authors reviewed the clinical features and responses to IV immunoglobulin (IVIg) treatment of patients with MMN with and without CB at diagnosis, after 4 years of follow-up ...

journal_title：Neurology

authors： Delmont E,Azulay JP,Giorgi R,Attarian S,Verschueren A,Uzenot D,Pouget J

更新日期：2006-08-22 00:00:00

abstract：:The authors measured the association of early ischemic change on CT scan, measured using the Alberta Stroke Programme Early CT score (ASPECTS), and functional outcome in 825 patients with anterior circulation stroke treated with IV thrombolysis within 3 hours of onset. ASPECTS predicted outcome in a graded fashion (li...

journal_title：Neurology

authors： Weir NU,Pexman JH,Hill MD,Buchan AM,CASES investigators.

更新日期：2006-08-08 00:00:00

abstract：BACKGROUND:Among patients with a patent foramen ovale (PFO) and a prior cryptogenic ischemic stroke or TIA, the absolute and relative risk of recurrent events is unclear. METHODS:We conducted a systematic review and meta-analysis of clinical studies in any language published up to February 2008. We included studies re...

journal_title：Neurology

authors： Almekhlafi MA,Wilton SB,Rabi DM,Ghali WA,Lorenzetti DL,Hill MD

更新日期：2009-07-14 00:00:00

abstract：:Because Hughlings Jackson directed that his personal documents be destroyed upon his death, none of his own clinical records are known. However, we have discovered several pages of notes in the Royal London Hospital Archive written in 1893 by Jackson to his House Physician at Queen Square concerning his proposals for ...

journal_title：Neurology

authors： Swash M,Evans J

更新日期：2006-08-22 00:00:00

abstract：OBJECTIVES:Assuming the involvement of homocysteine in a generalized small-vessel disease, we investigated the association of homocysteine levels with progression of white matter lesions, lacunar infarcts, and kidney disease. METHODS:Within the SMART-MR (Second Manifestations of ARTerial disease-Magnetic Resonance) St...

journal_title：Neurology

authors： Kloppenborg RP,Geerlings MI,Visseren FL,Mali WP,Vermeulen M,van der Graaf Y,Nederkoorn PJ,SMART Study Group.

更新日期：2014-03-04 00:00:00

abstract：:A case-control study was conducted to assess personal and family medical history and the appearance of Alzheimer's disease. We compared 98 men with clinically diagnosed Alzheimer's disease and 162 controls, matched by sex, year of birth, and town of residence. Family history of dementia and personal history of depress...

journal_title：Neurology

authors： Shalat SL,Seltzer B,Pidcock C,Baker EL Jr

更新日期：1987-10-01 00:00:00

abstract：:We investigated the role of ceruloplasmin in the antioxidative process in the brain in a patient with hereditary ceruloplasmin deficiency (HCD). Immunohistochemistry revealed an accumulation of Nepsilon-(carboxymethyl) lysine (CML) in basal ganglia of the HCD brain. In vitro study disclosed that ceruloplasmin inhibite...

journal_title：Neurology

authors： Tajima K,Kawanami T,Nagai R,Horiuchi S,Kato T

更新日期：1999-08-11 00:00:00

abstract：OBJECTIVE:To determine the effect of interferon-beta-1b (IFNbeta-1b) treatment on total contrast-enhancing lesions (CEL), white matter lesion load (WMLL), and cerebral atrophy (CA) in patients with relapsing-remitting multiple sclerosis (RRMS) using serial monthly MRI. METHODS:An open-label baseline-vs-treatment cross...

journal_title：Neurology

authors： Frank JA,Richert N,Bash C,Stone L,Calabresi PA,Lewis B,Stone R,Howard T,McFarland HF

更新日期：2004-03-09 00:00:00

abstract：BACKGROUND:Antiplatelets (APL), angiotensin-converting enzyme (ACE) inhibitors (ACEI), and statins (STAT) are commonly used for stroke prevention. The authors examined whether combination therapy with these agents has additive protective effects in reducing ischemic stroke severity. METHODS:The authors retrospectively...

journal_title：Neurology

authors： Kumar S,Savitz S,Schlaug G,Caplan L,Selim M

更新日期：2006-04-25 00:00:00

abstract：:Unusual late-onset complications of brain irradiation, characterized by reversible neurologic focal signs, seizures, and MRI alterations, have recently been reported and classified as stroke-like migraine attacks after radiation therapy (SMART)(1) and peri-ictal pseudoprogression (PIPG).(2.) ...

journal_title：Neurology

authors： Di Stefano AL,Berzero G,Vitali P,Galimberti CA,Ducray F,Ceroni M,Bastianello S,Colombo AA,Simoncelli A,Brunelli MC,Giometto B,Diamanti L,Gaviani P,Salmaggi A,Silvani A,Marchioni E

更新日期：2013-09-10 00:00:00

abstract：:We studied two families with an unusual variant of neurofibromatosis (NF). The first family had spinal neurofibromas and café au lait spots (CLS), the second spinal neurofibromas without CLS. Other signs of NF1 or NF2, such as cutaneous tumors, Lisch nodules, or acoustic tumors, were absent. The inheritance pattern in...

journal_title：Neurology

authors： Pulst SM,Riccardi VM,Fain P,Korenberg JR

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVE:Recent studies have suggested modifications of serotonin cerebral metabolism and of 5-HT(1A) receptors density in Alzheimer disease (AD). This study aims at exploring hippocampus 5-HT(1A) receptor density in patients at the amnesic mild cognitive impairment (aMCI) and mild AD dementia stages. METHODS:With us...

journal_title：Neurology

authors： Truchot L,Costes SN,Zimmer L,Laurent B,Le Bars D,Thomas-Antérion C,Croisile B,Mercier B,Hermier M,Vighetto A,Krolak-Salmon P

更新日期：2007-09-04 00:00:00

abstract：OBJECTIVE:To explore the causal relationships between sleep, major depressive disorder (MDD), and Alzheimer disease (AD). METHODS:We conducted bidirectional 2-sample Mendelian randomization analyses. Genetic associations were obtained from the largest genome-wide association studies currently available in UK Biobank (...

journal_title：Neurology

authors： Huang J,Zuber V,Matthews PM,Elliott P,Tzoulaki J,Dehghan A

更新日期：2020-10-06 00:00:00

abstract：BACKGROUND:Imaging determinations of the spatial extent of diffuse low-grade gliomas (DLGGs) are of paramount importance in evaluating the risk-to-benefit ratio of surgical resection. However, it is not clear how accurately preoperative conventional MRI can delineate DLGGs. METHODS:We report a retrospective histologic...

journal_title：Neurology

authors： Pallud J,Varlet P,Devaux B,Geha S,Badoual M,Deroulers C,Page P,Dezamis E,Daumas-Duport C,Roux FX

更新日期：2010-05-25 00:00:00

abstract：PURPOSE:To assess the extent of demyelination in cervical spondylotic myelopathy (CSM) using myelin water imaging (MWI) and electrophysiologic techniques. METHODS:Somatosensory evoked potentials (SSEPs) and MWI were acquired in 14 patients with CSM and 18 age-matched healthy controls. MWI was performed on a 3.0T whole...

journal_title：Neurology

authors： Liu H,MacMillian EL,Jutzeler CR,Ljungberg E,MacKay AL,Kolind SH,Mädler B,Li DKB,Dvorak MF,Curt A,Laule C,Kramer JLK

更新日期：2017-08-08 00:00:00

abstract：:Recent epidemiologic studies of multiple sclerosis (MS) in Australia defined the State of Queensland as a medium-frequency zone and the more southerly placed cities of Perth, Newcastle, and Hobart as high-frequency zones. Clinical profiles in the patient populations of both frequency zones were remarkably similar in m...

journal_title：Neurology

authors： Hammond SR,English D,de Wytt C,Maxwell IC,Millingen KS,Stewart-Wynne EG,McLeod JG,McCall MG

更新日期：1988-06-01 00:00:00

abstract：:Thyrotropin-releasing hormone (TRH) exerts many effects upon spinal cord function in animals, and may also play a role in human spinal cord function. We have used the technique of quantitative autoradiography to anatomically localize specific receptors for TRH within human spinal cord. Highest concentrations of TRH re...

journal_title：Neurology

authors： Manaker S,Winokur A,Rhodes CH,Rainbow TC

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:Differentiating idiopathic late-onset cerebellar ataxia (ILOCA) from ataxia due to the cerebellar subtype of multiple-system atrophy (MSA-C) can be difficult in the early stages of the disease METHODS:The authors analyzed the levels of various CSF biomarkers in 27 patients with MSA-C and 18 patients with IL...

journal_title：Neurology

authors： Abdo WF,van de Warrenburg BP,Munneke M,van Geel WJ,Bloem BR,Kremer HP,Verbeek MM

更新日期：2006-08-08 00:00:00

abstract：:Charcot-Marie-Tooth disease type 1 (CMT1) is associated with atrophy and degeneration of peripheral nerve axons in addition to prominent changes in the structure of Schwann cells. We have investigated the composition of the axonal cytoskeleton in sural nerve biopsies from patients with CMT1. Compared to controls, CMT1...

journal_title：Neurology

authors： Watson DF,Nachtman FN,Kuncl RW,Griffin JW

更新日期：1994-12-01 00:00:00