Acute late-onset encephalopathy after radiotherapy: an unusual life-threatening complication.


:Unusual late-onset complications of brain irradiation, characterized by reversible neurologic focal signs, seizures, and MRI alterations, have recently been reported and classified as stroke-like migraine attacks after radiation therapy (SMART)(1) and peri-ictal pseudoprogression (PIPG).(2.)






Di Stefano AL,Berzero G,Vitali P,Galimberti CA,Ducray F,Ceroni M,Bastianello S,Colombo AA,Simoncelli A,Brunelli MC,Giometto B,Diamanti L,Gaviani P,Salmaggi A,Silvani A,Marchioni E




Has Abstract


2013-09-10 00:00:00














  • APOE epsilon4 is not a susceptibility gene in idiopathic or diabetic sensory neuropathy.

    abstract::The presence of an APOE epsilon4 allele may be a risk factor for neuropathy severity in diabetes. The authors assessed the frequency of APOE epsilon4 in patients presenting with sensory predominant neuropathy. APOE epsilon4 frequency among patients with early diabetic neuropathy and impaired glucose tolerance-associat...


    pub_type: 杂志文章


    authors: Zhou Z,Hoke A,Cornblath DR,Griffin JW,Polydefkis M

    更新日期:2005-01-11 00:00:00

  • Multiple sclerosis and childhood infections.

    abstract::Migration from an area where MS is common to an area where it is rare (and vice versa) affects the risk of MS, provided migration occurs in childhood. A childhood infection might explain this effect. Therefore, the age pattern of infectious diseases in different regions was examined. A higher proportion of children sh...


    pub_type: 杂志文章


    authors: Alter M,Zhang ZX,Davanipour Z,Sobel E,Zibulewski J,Schwartz G,Friday G

    更新日期:1986-10-01 00:00:00

  • The ability of persons with Alzheimer disease (AD) to make a decision about taking an AD treatment.

    abstract:OBJECTIVE:To examine the severity of impairments in the decision-making abilities (understanding, appreciation, reasoning, and choice) and competency to make a decision to use an Alzheimer disease (AD)-slowing medication in patients with AD and the relationships between these impairments, insight, and overall cognition...


    pub_type: 杂志文章


    authors: Karlawish JH,Casarett DJ,James BD,Xie SX,Kim SY

    更新日期:2005-05-10 00:00:00

  • Quantitation of herpes simplex virus type 1 DNA in cells of cerebrospinal fluid of patients with herpes simplex virus encephalitis.

    abstract::We used a nested polymerase chain reaction assay to quantitate the number of viral copies in cells of CSF of eight patients with herpes simplex virus encephalitis (HSVE). The viral load was monitored in serial CSF samples during the course of disease and correlated to clinical symptoms, radiologic manifestations, effi...


    pub_type: 杂志文章


    authors: Wildemann B,Ehrhart K,Storch-Hagenlocher B,Meyding-Lamadé U,Steinvorth S,Hacke W,Haas J

    更新日期:1997-05-01 00:00:00

  • Optical coherence tomography helps differentiate neuromyelitis optica and MS optic neuropathies.

    abstract:OBJECTIVE:To evaluate the retinal nerve fiber layer (RNFL) thickness and macular volume in neuromyelitis optica (NMO) spectrum patients using optical coherence tomography (OCT). BACKGROUND:OCT can quantify damage to retinal ganglion cell axons and can identify abnormalities in multiple sclerosis and optic neuritis (ON...


    pub_type: 杂志文章


    authors: Ratchford JN,Quigg ME,Conger A,Frohman T,Frohman E,Balcer LJ,Calabresi PA,Kerr DA

    更新日期:2009-07-28 00:00:00

  • Weekly alcohol consumption, cigarette smoking, and the risk of ischemic stroke: results of a case-control study at three urban medical centers in Chicago, Illinois.

    abstract::To assess the role of current weekly alcohol consumption as a risk factor for cerebral infarction, we administered a pretested questionnaire to 205 middle-aged and elderly acute ischemic stroke patients and 410 outpatient controls matched by age, sex, race, and method of hospital payment. The frequency of hypertension...


    pub_type: 杂志文章


    authors: Gorelick PB,Rodin MB,Langenberg P,Hier DB,Costigan J

    更新日期:1989-03-01 00:00:00

  • Aberrant neural circuits in malformations of cortical development and focal epilepsy.

    abstract::Malformations of cortical development (MCD) account for a high proportion of medically resistant partial seizures in children and figure prominently in pediatric surgical series. In contrast to the results of epilepsy surgery for postnatally acquired lesions, seizure freedom in patients with MCD is less certain owing ...


    pub_type: 杂志文章,评审


    authors: Duchowny M,Jayakar P,Levin B

    更新日期:2000-08-08 00:00:00

  • Effect of insurance status on postacute care among working age stroke survivors.

    abstract:OBJECTIVE:Utilization of postacute care is associated with improved poststroke outcomes. However, more than 20% of American adults under age 65 are uninsured. We sought to determine whether insurance status is associated with utilization and intensity of institutional postacute care among working age stroke survivors. ...


    pub_type: 杂志文章


    authors: Skolarus LE,Meurer WJ,Burke JF,Prvu Bettger J,Lisabeth LD

    更新日期:2012-05-15 00:00:00

  • Diagnostic accuracy of confrontation visual field tests.

    abstract:OBJECTIVE:To determine the diagnostic accuracy of confrontation visual field testing and to compare the accuracy of confrontation tests both individually and in combination. METHODS:Patients were prospectively recruited from ophthalmology clinics over a 6-month period. All patients underwent SITA-standard 24-2 Humphre...


    pub_type: 杂志文章


    authors: Kerr NM,Chew SS,Eady EK,Gamble GD,Danesh-Meyer HV

    更新日期:2010-04-13 00:00:00

  • Demyelinating neuropathy due to primary IgM kappa B cell lymphoma of peripheral nerve.

    abstract::A 53-year-old man presented with a painful, demyelinating sensorimotor peripheral neuropathy with lymphomatous infiltration on sural nerve biopsy, but no evidence of systemic lymphoma. The neuropathy responded to cytotoxic therapy. Seven years later he developed generalized lymphadenopathy due to B cell lymphoplasmacy...


    pub_type: 杂志文章


    authors: Ince PG,Shaw PJ,Fawcett PR,Bates D

    更新日期:1987-07-01 00:00:00

  • Residual function in motor cortex contralateral to amputated hand.

    abstract:OBJECTIVE:To investigate residual function of the motor cortex corresponding to the hand of the amputated arm (MCamp). METHODS:Focal transcranial magnetic stimulation (TMS) of MCamp was performed in 10 patients 22 to 52 years after arm amputation to inhibit tonic muscle contraction in the intact hand ipsilateral to co...


    pub_type: 杂志文章


    authors: Röricht S,Meyer BU

    更新日期:2000-02-22 00:00:00

  • Cognitive deficits of pure subcortical vascular dementia vs. Alzheimer disease: PiB-PET-based study.

    abstract:OBJECTIVES:Despite many neuropsychological studies to differentiate subcortical vascular dementia (SVaD) from Alzheimer disease (AD), previous studies did not eliminate confounding effects of mixed Alzheimer and vascular pathology. We aimed to investigate neuropsychological differences between patients with Pittsburgh ...


    pub_type: 杂志文章


    authors: Yoon CW,Shin JS,Kim HJ,Cho H,Noh Y,Kim GH,Chin JH,Oh SJ,Kim JS,Choe YS,Lee KH,Lee JH,Seo SW,Na DL

    更新日期:2013-02-05 00:00:00

  • Alexander disease: ventricular garlands and abnormalities of the medulla and spinal cord.

    abstract:BACKGROUND:Alexander disease is most commonly associated with macrocephaly and, on MRI, a leukoencephalopathy with frontal preponderance. The disease is caused by mutation of the GFAP gene. Clinical and MRI phenotypic variation have been increasingly recognized. METHODS:The authors studied seven patients with Alexande...


    pub_type: 杂志文章


    authors: van der Knaap MS,Ramesh V,Schiffmann R,Blaser S,Kyllerman M,Gholkar A,Ellison DW,van der Voorn JP,van Dooren SJ,Jakobs C,Barkhof F,Salomons GS

    更新日期:2006-02-28 00:00:00

  • The value of intracranial pressure monitoring in acute hemispheric stroke.

    abstract:BACKGROUND AND PURPOSE:Persistently elevated intracranial pressure (ICP) has been associated with poor clinical outcome after severe brain injury, such as neurotrauma, intracerebral hemorrhage, and subarachnoidal hemorrhage. Although ICP monitoring is increasingly being used in intensive care treatment of patients with...


    pub_type: 杂志文章


    authors: Schwab S,Aschoff A,Spranger M,Albert F,Hacke W

    更新日期:1996-08-01 00:00:00

  • A double-blind study comparing carbamazepine with phenytoin as initial seizure therapy in adults.

    abstract::Carbamazepine was compared with phenytoin in a double-blind study. Of 87 patients, data on 70 patients were complete and used for analysis. Thirty-five patients were treated with each drug. The incidence of major side effects, minor side effects, and complete control (85%) was the same in both groups. A mild but signi...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Ramsay RE,Wilder BJ,Berger JR,Bruni J

    更新日期:1983-07-01 00:00:00

  • Factors influencing sweat gland innervation in diabetes.

    abstract:BACKGROUND:Using a stereologic approach, the density of nerve fibers innervating sweat gland (SG) fragments in patients with diabetes mellitus (DM) and healthy controls using protein gene product (PGP), tyrosine hydroxylase (TH), and vasoactive intestinal peptide (VIP) was measured to determine which marker best detect...


    pub_type: 杂志文章


    authors: Liu Y,Billiet J,Ebenezer GJ,Pan B,Hauer P,Wei J,Polydefkis M

    更新日期:2015-04-21 00:00:00

  • Response of cluster headache to psilocybin and LSD.

    abstract::The authors interviewed 53 cluster headache patients who had used psilocybin or lysergic acid diethylamide (LSD) to treat their condition. Twenty-two of 26 psilocybin users reported that psilocybin aborted attacks; 25 of 48 psilocybin users and 7 of 8 LSD users reported cluster period termination; 18 of 19 psilocybin ...


    pub_type: 杂志文章


    authors: Sewell RA,Halpern JH,Pope HG Jr

    更新日期:2006-06-27 00:00:00

  • Standard operating procedures improve acute neurologic care in a sub-Saharan African setting.

    abstract:OBJECTIVE:Quality of neurologic emergency management in an under-resourced country may be improved by standard operating procedures (SOPs). METHODS:Neurologic SOPs were implemented in a large urban (Banjul) and a small rural (Brikama) hospital in the Gambia. As quality indicators of neurologic emergency management, pe...


    pub_type: 杂志文章


    authors: Jaiteh LES,Helwig SA,Jagne A,Ragoschke-Schumm A,Sarr C,Walter S,Lesmeister M,Manitz M,Blaß S,Weis S,Schlund V,Bah N,Kauffmann J,Fousse M,Kangankan S,Ramos Cabrera A,Kronfeld K,Ruckes C,Liu Y,Nyan O,Fassbender K

    更新日期:2017-07-11 00:00:00

  • Is late-onset multiple sclerosis associated with a worse outcome?

    abstract:OBJECTIVE:To describe the characteristics of late-onset multiple sclerosis (MS) (LOMS, 50+ years) vs adult-onset MS (AOMS, 16 to <50 years) and examine prognosis and associated risk factors. METHODS:Patients with definite MS, onset prior to July 1988, registered with a BCMS clinic before July 1998, with at least one E...


    pub_type: 杂志文章


    authors: Tremlett H,Devonshire V

    更新日期:2006-09-26 00:00:00

  • Familial frontotemporal dementia with ubiquitin-positive, tau-negative inclusions.

    abstract:OBJECTIVE:To describe the clinical features, neuropathology, and genetic studies in a family with autosomal dominant frontotemporal dementia (FTD). BACKGROUND:Clinical Pick's disease, or FTD with parkinsonism, has been described in several families linked to chromosome 17 (FTDP-17). Most of these have shown tau protei...


    pub_type: 杂志文章


    authors: Kertesz A,Kawarai T,Rogaeva E,St George-Hyslop P,Poorkaj P,Bird TD,Munoz DG

    更新日期:2000-02-22 00:00:00

  • The ALS-FTD-Q: a new screening tool for behavioral disturbances in ALS.

    abstract:OBJECTIVE:The assessment of behavioral disturbances in amyotrophic lateral sclerosis (ALS) is important because of the overlap with the behavioral variant of frontotemporal dementia (ALS-bvFTD). Motor symptoms and dysarthria are not taken into account in currently used behavioral questionnaires. We examined the clinime...


    pub_type: 杂志文章


    authors: Raaphorst J,Beeldman E,Schmand B,Berkhout J,Linssen WH,van den Berg LH,Pijnenburg YA,Grupstra HF,Weikamp JG,Schelhaas HJ,Papma JM,van Swieten JC,de Visser M,de Haan RJ

    更新日期:2012-09-25 00:00:00

  • Saccadic duration and intrasaccadic fatigue in myasthenic and nonmyasthenic ocular palsies.

    abstract::We measured the duration and amplitude of saccades in three normal subjects, eight patients with myasthenia gravis, and eight patients with nonmyasthenic ocular palsies. Saccades were examined at the start of a repetitive saccade task, after 3 minutes of activity, and 1 minute after administration of edrophonium. The ...


    pub_type: 杂志文章


    authors: Barton JJ,Jama A,Sharpe JA

    更新日期:1995-11-01 00:00:00

  • Blood buffy coat from Alzheimer's disease patients and their relatives does not transmit spongiform encephalopathy to hamsters.

    abstract::There was a report of spongiform encephalopathy transmitted to Syrian hamsters by intracerebral inoculation with the blood buffy coat of patients with Alzheimer's disease (AD) and their unaffected first-degree relatives. We attempted to verify that report, taking measures to reduce the risk of contaminating samples wi...


    pub_type: 杂志文章


    authors: Godec MS,Asher DM,Kozachuk WE,Masters CL,Rubi JU,Payne JA,Rubi-Villa DJ,Wagner EE,Rapoport SI,Schapiro MB

    更新日期:1994-06-01 00:00:00

  • Relationship of UV exposure to prevalence of multiple sclerosis in England.

    abstract:OBJECTIVE:To assess the potential relationship of ultraviolet B radiation (UVB) and Epstein-Barr virus (EBV) exposure in explaining the period prevalence of multiple sclerosis (MS) in England. METHODS:English national Hospital Episode Statistics covering all admissions to National Health Service hospitals in England i...


    pub_type: 杂志文章


    authors: Ramagopalan SV,Handel AE,Giovannoni G,Rutherford Siegel S,Ebers GC,Chaplin G

    更新日期:2011-04-19 00:00:00

  • Accuracy of family history data on Parkinson's disease.

    abstract:BACKGROUND:Genetic studies of PD frequently rely on family history interviews (FHI), yet the accuracy of data obtained in this way is unclear. OBJECTIVE:To assess the interinformant reliability and validity of family history information on PD in first-degree relatives of PD cases and controls. METHODS:A structured FH...


    pub_type: 杂志文章


    authors: Marder K,Levy G,Louis ED,Mejia-Santana H,Cote L,Andrews H,Harris J,Waters C,Ford B,Frucht S,Fahn S,Ottman R

    更新日期:2003-07-08 00:00:00

  • Establishment of epilepsy surgery in Peru.

    abstract::Epilepsy surgery is a well-established treatment for certain types of intractable epilepsy. While there is a relatively high number of epilepsy surgery centers in Canada and the United States, the same cannot be said about many other parts of the world, such as South America. Although there are notable exceptions, suc...


    pub_type: 杂志文章


    authors: Steven DA,Vasquez CM,Delgado JC,Zapata-Luyo W,Becerra A,Barreto E,Arango MF,Burneo JG

    更新日期:2018-08-21 00:00:00

  • COMT inhibitors and liver toxicity.

    abstract::This paper reviews the issue of hepatotoxicity with the use of the catechol-O-methly transferase (COMT) inhibitors tolcapone and entacapone. Neither drug caused hepatotoxicity in preclinical toxicity testing. However, in clinical trials of tolcapone, liver chemistry tests were elevated more than 3 times above the uppe...


    pub_type: 杂志文章,评审


    authors: Watkins P

    更新日期:2000-01-01 00:00:00

  • Silent stroke in the NINCDS Stroke Data Bank.

    abstract::Previous brain infarctions seen on CT are common in the absence of history of stroke. Eleven percent of patients (135/1,203) without stroke history had ischemic lesions on their first CT, unrelated to the presenting stroke. Stroke Data Bank files were reviewed to determine whether the occurrence, location, and CT char...


    pub_type: 杂志文章


    authors: Chodosh EH,Foulkes MA,Kase CS,Wolf PA,Mohr JP,Hier DB,Price TR,Furtado JG Jr

    更新日期:1988-11-01 00:00:00

  • Refractory status epilepticus in children with and without prior epilepsy or status epilepticus.

    abstract:OBJECTIVE:To compare refractory convulsive status epilepticus (rSE) management and outcome in children with and without a prior diagnosis of epilepsy and with and without a history of status epilepticus (SE). METHODS:This was a prospective observational descriptive study performed from June 2011 to May 2016 on pediatr...


    pub_type: 杂志文章,多中心研究


    authors: Sánchez Fernández I,Jackson MC,Abend NS,Arya R,Brenton JN,Carpenter JL,Chapman KE,Gaillard WD,Gaínza-Lein M,Glauser TA,Goldstein JL,Goodkin HP,Helseth A,Kapur K,McDonough TL,Mikati MA,Peariso K,Riviello J Jr,Tasker RC

    更新日期:2017-01-24 00:00:00

  • Multiple sclerosis prevalence in the United States commercially insured population.

    abstract:OBJECTIVE:To estimate the US commercially insured multiple sclerosis (MS) annual prevalence from 2008 to 2012. METHODS:The study was a retrospective analysis using PharMetrics Plus, a nationwide claims database for over 42 million covered US representative lives. Annual point prevalence required insurance eligibility ...


    pub_type: 杂志文章


    authors: Dilokthornsakul P,Valuck RJ,Nair KV,Corboy JR,Allen RR,Campbell JD

    更新日期:2016-03-15 00:00:00