Abstract:
:Among 50 patients with phenytoin intoxication, 14 had seizures during the episode. Seizures in 9 of these 14 patients probably resulted from poor seizure control despite high phenytoin levels, but in 5 cases, attacks were attributed to phenytoin toxicity. The only factor that seemed to correlate with seizures was a serum phenytoin level over 30 micrograms/ml. No demographic, metabolic, neuropsychiatric, or therapeutic variables were predictive; nor were any other symptoms of toxicity particularly likely to be found in association with seizures. Seizures are an occasional manifestation of phenytoin toxicity, particularly when levels are high.
journal_name
Neurologyjournal_title
Neurologyauthors
Stilman N,Masdeu JCdoi
10.1212/wnl.35.12.1769subject
Has Abstractpub_date
1985-12-01 00:00:00pages
1769-72issue
12eissn
0028-3878issn
1526-632Xjournal_volume
35pub_type
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