Creutzfeldt-Jakob disease associated with a deletion of two repeats in the prion protein gene.

abstract：OBJECTIVES:To provide information on the effect of the coronavirus disease of 2019 (COVID-19) pandemic on people with epilepsy and provide consensus recommendations on how to provide the best possible care for people with epilepsy while avoiding visits to urgent care facilities and hospitalizations during the novel cor...

journal_title：Neurology

authors： French JA,Brodie MJ,Caraballo R,Devinsky O,Ding D,Jehi L,Jette N,Kanner A,Modi AC,Newton CR,Patel AA,Pennell PB,Perucca E,Sander JW,Scheffer IE,Singh G,Williams E,Wilmshurst J,Cross JH

更新日期：2020-06-09 00:00:00

abstract：BACKGROUND:While stable xenon CT (Xe-CT) cerebral blood flow (CBF) is an accepted standard for quantitative assessment of cerebral hemodynamics, the accuracy of magnetic resonance perfusion-weighted imaging (PWI-MRI) is unclear. The Improved PWI Methodology in Acute Clinical Stroke Study compares PWI findings with Xe-C...

journal_title：Neurology

authors： Olivot JM,Mlynash M,Zaharchuk G,Straka M,Bammer R,Schwartz N,Lansberg MG,Moseley ME,Albers GW

更新日期：2009-03-31 00:00:00

abstract：:Arm-diaphragm synkinesis may occur after injury to the proximal portion of the brachial plexus or cervical nerve roots. Regenerating axons of phrenic motor neurons are misdirected to supply limb muscles. Electrodiagnostic investigations of three patients with symptoms referable to upper brachial plexus or cervical roo...

journal_title：Neurology

authors： Swift TR,Leshner RT,Gross JA

更新日期：1980-04-01 00:00:00

abstract：:A woman with typical features of myoclonic epilepsy with ragged red fibers (MERRF) had a novel heteroplasmic mutation (G611A) in the mitochondrial DNA tRNA phenylalanine gene. The mutation was heteroplasmic (91%) in muscle but undetectable in accessible tissues from the patient and her maternal relatives. Single-fiber...

journal_title：Neurology

authors： Mancuso M,Filosto M,Mootha VK,Rocchi A,Pistolesi S,Murri L,DiMauro S,Siciliano G

更新日期：2004-06-08 00:00:00

abstract：:In many parkinsonian syndromes, neuromelanin (NM)-containing dopaminergic neurons of the substantia nigra (SN) are selectively targeted by the noxius pathogens. Studies of the constitutional and functional features of human NM allow the formulation of a logical hypothesis on its role in parkinsonian syndromes. In the ...

journal_title：Neurology

authors： Zecca L,Zucca FA,Albertini A,Rizzio E,Fariello RG

更新日期：2006-10-10 00:00:00

abstract：OBJECTIVE:Precise genetic analyses were conducted with ring finger protein 213 (RNF213) in relation to a particular clinical phenotype in Chinese patients with moyamoya disease (MMD) to determine whether heterozygosity is responsible for the early-onset and severe form of this disease. METHODS:A case-control study for...

journal_title：Neurology

authors： Wang Y,Zhang Z,Wei L,Zhang Q,Zou Z,Yang L,Li D,Shang M,Han C,Mambiya M,Bao X,Li Q,Hao F,Zhang K,Wang H,Liu S,Liu M,Zeng F,Nie F,Wang K,Liu W,Duan L

更新日期：2020-02-18 00:00:00

abstract：OBJECTIVE:To investigate whether cognitive function is related to incidence of stroke. METHODS:A population-based cohort of 1551 subjects with no clinical history or signs of stroke, age 75 years and over at baseline, were followed up for 3 years. Individuals with a first-ever stroke event that was recorded in the Sto...

journal_title：Neurology

authors： Zhu L,Fratiglioni L,Guo Z,Winblad B,Viitanen M

更新日期：2000-06-13 00:00:00

abstract：:The authors correlated neurologic features of rostral lateral pontine infarct (rLPI) with lesion location on MRI. rLPI is a motor-sensory stroke presenting as crural monoparesis or crural dominant hemiparesis and segmental superficial or deep sensory disturbances. The dorsolateral pontine base causes crural paresis wi...

journal_title：Neurology

authors： Kataoka S,Miaki M,Saiki M,Saiki S,Yamaya Y,Hori A,Hirose G

更新日期：2003-07-08 00:00:00

abstract：OBJECTIVE:To evaluate the effect of amyloid imaging on clinical decision making. METHODS:We conducted a retrospective analysis of 140 cognitively impaired patients (mean age 65.0 years, 46% primary β-amyloid (Aβ) diagnosis, mean Mini-Mental State Examination 22.3) who underwent amyloid (Pittsburgh compound B [PiB]) PE...

journal_title：Neurology

authors： Sánchez-Juan P,Ghosh PM,Hagen J,Gesierich B,Henry M,Grinberg LT,O'Neil JP,Janabi M,Huang EJ,Trojanowski JQ,Vinters HV,Gorno-Tempini M,Seeley WW,Boxer AL,Rosen HJ,Kramer JH,Miller BL,Jagust WJ,Rabinovici GD

更新日期：2014-01-21 00:00:00

abstract：:Rare reflex epilepsies are a clinical curiosity but may also give insight into neurocognitive processes. The authors present a patient whose seizures were precipitated by drawing but not by writing. This dissociation complements previous reports on selective impairment of writing. EEG revealed a focus in the right fro...

journal_title：Neurology

authors： Kho KH,van den Bergh WM,Spetgens WP,Leijten FS

更新日期：2006-03-14 00:00:00

abstract：:The authors have developed an MG activities of daily living (ADL) profile (MG-ADL)-a simple eight-question survey of MG symptoms. In 254 consecutive encounters with established MG patients, the authors compared scores from the MG-ADL to the quantitative MG score (QMG)-a standardized, reliable scale used in clinical tr...

journal_title：Neurology

authors： Wolfe GI,Herbelin L,Nations SP,Foster B,Bryan WW,Barohn RJ

更新日期：1999-04-22 00:00:00

abstract：:Recent evidence suggests that the vasopressin analogue desglycinamide-arginine8-vasopressin (DGAVP) might specifically benefit mild brain trauma patients. We investigated the effect of intranasal DGAVP treatment in 32 patients who had sustained a mild head injury for 3 months in a double-blind, placebo-controlled, mat...

journal_title：Neurology

authors： Bohnen NI,Twijnstra A,Jolles J

更新日期：1993-01-01 00:00:00

abstract：:The prevalence of spontaneous lingual-facial-buccal movements was determined in 661 patients between the ages of 50 and 79 without neuroleptic exposure or known CNS disease. The prevalence was 0.8% between ages 50 and 59, 6% between ages 60 and 69, and 7.8% between ages 70 and 79. ...

journal_title：Neurology

authors： Klawans HL,Barr A

更新日期：1982-05-01 00:00:00

abstract：OBJECTIVE:To use a historical placebo control design to determine whether lithium carbonate slows progression of amyotrophic lateral sclerosis (ALS). METHODS:A phase II trial was conducted at 10 sites in the Western ALS Study Group using similar dosages (300-450 mg/day), target blood levels (0.3-0.8 mEq/L), outcome me...

journal_title：Neurology

authors： Miller RG,Moore DH,Forshew DA,Katz JS,Barohn RJ,Valan M,Bromberg MB,Goslin KL,Graves MC,McCluskey LF,McVey AL,Mozaffar T,Florence JM,Pestronk A,Ross M,Simpson EP,Appel SH,WALS Study Group.

更新日期：2011-09-06 00:00:00

abstract：:Prompted by the observation that a fellow medical student sneezed at about the same time in class every morning, we recorded the time of each of the 118 sneezes she made on 69 days over a 6.5-month period. Analysis of the sneeze times with the goodness-of-fit test revealed a highly nonuniform distribution (p < 0.0001)...

journal_title：Neurology

authors： Grant AC,Roter EP

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVE:It is known that muscle phosphorylase deficiency restricts carbohydrate utilization, but the implications for muscle fat metabolism have not been studied. We questioned whether patients with McArdle disease can compensate for the blocked muscle glycogen breakdown by enhancing fat oxidation during exercise. M...

journal_title：Neurology

authors： Ørngreen MC,Jeppesen TD,Andersen ST,Taivassalo T,Hauerslev S,Preisler N,Haller RG,van Hall G,Vissing J

更新日期：2009-02-24 00:00:00

abstract：:We developed a method for the detection of Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) carriers. The method is based on the quantitative analysis of the products of standard multiplex polymerase chain reaction (PCR) from 18 different exons of the dystrophin gene, and is designated "QM-PCR." W...

journal_title：Neurology

authors： Ioannou P,Christopoulos G,Panayides K,Kleanthous M,Middleton L

更新日期：1992-09-01 00:00:00

abstract：:This community-based study analyzed 54 patients with definite or probable tuberculous meningitis (TBM) in New Mexico from 1970 through 1990. Patients ranged in age from 4 months to 86 years. The highest age-specific incidence occurred in the elderly, but 22% of patients were less than 10 years old. Native American pat...

journal_title：Neurology

authors： Davis LE,Rastogi KR,Lambert LC,Skipper BJ

更新日期：1993-09-01 00:00:00

abstract：OBJECTIVE:To estimate the prevalence of childhood ataxia resulting from both genetic and acquired causes. METHODS:A systematic review was conducted following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) statement. Five databases were searched for articles reporting a frequency measur...

journal_title：Neurology

authors： Musselman KE,Stoyanov CT,Marasigan R,Jenkins ME,Konczak J,Morton SM,Bastian AJ

更新日期：2014-01-07 00:00:00

abstract：OBJECTIVE:To report eight cases of sensory Guillain-Barré syndrome (GBS). BACKGROUND:The concept of sensory equivalent to ascending paralysis of GBS was raised in 1958, and the diagnostic criteria for a sensory loss and areflexia variant of GBS were proposed in 1981. However, clinical cases meeting these criteria have...

journal_title：Neurology

authors： Oh SJ,LaGanke C,Claussen GC

更新日期：2001-01-09 00:00:00

abstract：:Men and women with dementia of the Alzheimer type (DAT) had more brain atrophy and ventricular dilatation, measured by quantitative CT, than did respective age- and sex-matched healthy controls (p less than 0.05). The male DAT patients with mild dementia had a larger mean third ventricle volume, whereas male patients ...

journal_title：Neurology

authors： Creasey H,Schwartz M,Frederickson H,Haxby JV,Rapoport SI

更新日期：1986-12-01 00:00:00

abstract：OBJECTIVE:To investigate residual function of the motor cortex corresponding to the hand of the amputated arm (MCamp). METHODS:Focal transcranial magnetic stimulation (TMS) of MCamp was performed in 10 patients 22 to 52 years after arm amputation to inhibit tonic muscle contraction in the intact hand ipsilateral to co...

journal_title：Neurology

authors： Röricht S,Meyer BU

更新日期：2000-02-22 00:00:00

abstract：:Seronegative (SN) patients with myasthenia gravis (MG) have clinical and electrophysiologic features similar to those of seropositive (SP) patients, and they respond to the same therapeutic measures. However, because SN patients lack detectable (by standard radioimmunoassays) serum antibodies to acetylcholine receptor...

journal_title：Neurology

authors： Karni A,Zisman E,Katz-Levy Y,Paas-Rozner M,Dayan M,Brautbar C,Abramsky O,Sela M,Mozes E

更新日期：1997-06-01 00:00:00

abstract：OBJECTIVE:To report 2 patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) who presented acutely with Miller Fisher syndrome and polyneuritis cranialis, respectively. METHODS:Patient data were obtained from medical records from the University Hospital "Príncipe de Asturias," Alcalá de He...

journal_title：Neurology

authors： Gutiérrez-Ortiz C,Méndez-Guerrero A,Rodrigo-Rey S,San Pedro-Murillo E,Bermejo-Guerrero L,Gordo-Mañas R,de Aragón-Gómez F,Benito-León J

更新日期：2020-08-04 00:00:00

abstract：:The mechanism by which prednisone improves muscle strength and function in Duchenne muscular dystrophy (DMD) is unknown. We addressed the possibility that clinical improvement was related to prednisone-induced alterations in skeletal muscle dystrophin. We performed muscle biopsies on patients at the conclusion of a ra...

journal_title：Neurology

authors： Burrow KL,Coovert DD,Klein CJ,Bulman DE,Kissel JT,Rammohan KW,Burghes AH,Mendell JR

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:According to the International Classification of Headache Disorders (ICHD)-2, primary daily headaches unremitting from onset are classified as new daily-persistent headache (NDPH) only if migraine features are absent. When migraine features are present, classification is problematic. METHODS:We developed a ...

journal_title：Neurology

authors： Robbins MS,Grosberg BM,Napchan U,Crystal SC,Lipton RB

更新日期：2010-04-27 00:00:00

abstract：OBJECTIVE:To estimate whole-brain microinfarct burden from microinfarct counts in routine postmortem examination. METHODS:We developed a simple mathematical method to estimate the total number of cerebral microinfarcts from counts obtained in the small amount of tissue routinely examined in brain autopsies. We derived...

journal_title：Neurology

authors： Westover MB,Bianchi MT,Yang C,Schneider JA,Greenberg SM

更新日期：2013-04-09 00:00:00

abstract：:A wide variety of movement disorders are associated with alcohol abuse. Some idiopathic movement disorders are markedly improved by small amounts of alcohol and this response occasionally may lead to alcoholism. Alcohol abuse alone or combined with hepatic encephalopathy can cause various types of tremor, asterixis, a...

journal_title：Neurology

authors： Neiman J,Lang AE,Fornazzari L,Carlen PL

更新日期：1990-05-01 00:00:00

abstract：:Immitation synkinesia is usually associated with thalamic or parietal lesions. Analysis of three cases shows that the lesions may affect the posterior columns of the spinal cord or even the peripheral nervous system. In our cases, two facts stand out, a large measure of integrity of motor activity and predominant dist...

journal_title：Neurology

authors： Cambier J,Dehen H

更新日期：1977-07-01 00:00:00

abstract：:The effects of lysine vasopressin on memory and cognitive deficits in Alzheimer disease was investigated. In a double-blind study, seven patients were given 16 units of lysine vasopressin per day for 10 days and were compared with seven different patients receiving placebo. No significant difference in performance bet...

journal_title：Neurology

authors： Durso R,Fedio P,Brouwers P,Cox C,Martin AJ,Ruggieri SA,Tamminga CA,Chase TN

更新日期：1982-06-01 00:00:00