New-onset afebrile seizures in infants: role of neuroimaging.

abstract：:Duchenne muscular dystrophy manifested in one of girl twins. The twins were monozygous on the basis of red cell and HL antigens and skin graft compatibility. Karyotyping, including banding techniques, showed a normal number of chromosomes and a normal configuration of the X-chromosome in both twins. The twins were ide...

journal_title：Neurology

authors： Gomez MR,Engel AG,Dewald G,Peterson HA

更新日期：1977-06-01 00:00:00

abstract：OBJECTIVE:To identify the level of evidence for use of nusinersen to treat spinal muscular atrophy (SMA) and review clinical considerations regarding use. METHODS:The author panel systematically reviewed nusinersen clinical trials for patients with SMA and assigned level of evidence statements based on the American Ac...

journal_title：Neurology

authors： Michelson D,Ciafaloni E,Ashwal S,Lewis E,Narayanaswami P,Oskoui M,Armstrong MJ

更新日期：2018-11-13 00:00:00

abstract：:Cost-effective approaches for arriving at correct diagnoses should be used. Herein, we compare three approaches for the differential diagnosis of a common neurologic syndrome, peripheral neuropathy. In the "shotgun" approach, a standard battery of hematologic, biochemical, serologic, antibody, enzyme, molecular geneti...

journal_title：Neurology

authors： Dyck PJ,Dyck PJ,Grant IA,Fealey RD

更新日期：1996-07-01 00:00:00

abstract：:We studied the efficacy of divalproex sodium in patients with complex partial seizures taking concomitant carbamazepine or phenytoin as monotherapy. Patients were selected because of inadequate seizure control by current therapy. The primary efficacy measure was median reduction of seizure frequency during add-on trea...

journal_title：Neurology

authors： Willmore LJ,Shu V,Wallin B

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:To analyze differences in functional brain images collected in patients with type 2 and type 1 narcolepsy compared to normal controls and the relationship among brain images, objective neuropsychologic tests, and sleep findings. METHODS:Data collection included comprehensive clinical investigation, study of ...

journal_title：Neurology

authors： Huang YS,Hsiao IT,Liu FY,Hwang FM,Lin KL,Huang WC,Guilleminault C

更新日期：2018-04-24 00:00:00

abstract：BACKGROUND:Progressive brain atrophy in multiple sclerosis (MS) may reflect neuroaxonal and myelin loss and MRI measures of brain tissue loss are used as outcome measures in MS treatment trials. This study investigated sample sizes required to demonstrate reduction of brain atrophy using three outcome measures in a par...

journal_title：Neurology

authors： Altmann DR,Jasperse B,Barkhof F,Beckmann K,Filippi M,Kappos LD,Molyneux P,Polman CH,Pozzilli C,Thompson AJ,Wagner K,Yousry TA,Miller DH

更新日期：2009-02-17 00:00:00

abstract：:We have described four cases of medial plantar neuropathy that was confirmed by the near-nerve sensory nerve conduction study. The common compression site in medial plantar neuropathy is at the entrance to the fibromuscular tunnel behind the navicular tuberosity, distal to the tarsal tunnel, where Tinel's sign is loca...

journal_title：Neurology

authors： Oh SJ,Lee KW

更新日期：1987-08-01 00:00:00

abstract：OBJECTIVE:We aimed to assess sensitivity and specificity of the updated criteria for behavioral variant frontotemporal dementia (bvFTD) based on a large autopsy-confirmed cohort of patients with dementia. METHODS:Two hundred thirty-nine consecutive pathologically confirmed dementia patients, clinically assessed in a s...

journal_title：Neurology

authors： Harris JM,Gall C,Thompson JC,Richardson AM,Neary D,du Plessis D,Pal P,Mann DM,Snowden JS,Jones M

更新日期：2013-05-14 00:00:00

abstract：OBJECTIVE:To characterize comorbid chronic conditions, describe health services use, and estimate health care costs among community-dwelling older adults with prior stroke. METHODS:This is a retrospective cohort study using administrative data from Ontario, Canada. We identified all community-dwelling individuals aged...

journal_title：Neurology

authors： Gruneir A,Griffith LE,Fisher K,Panjwani D,Gandhi S,Sheng L,Patterson C,Gafni A,Ploeg J,Markle-Reid M

更新日期：2016-11-15 00:00:00

abstract：:While intracranial tuberculomas have become uncommon in industrial nations, 12 patients with signs and symptoms of an intracranial mass lesion were recently found to have tuberculomas. Clinical findings suggestive of tuberculosis were frequently subtle or absent. Five patients did not have extracranial tuberculosis. T...

journal_title：Neurology

authors： Mayers MM,Kaufman DM,Miller MH

更新日期：1978-03-01 00:00:00

abstract：OBJECTIVE:We aimed to analyze lesion patterns of lacunae-sized infarctions in the perforating arterial territory in terms of shape and to determine whether the particular pattern of conglomerated beads shape affected early neurologic deterioration. METHODS:We consecutively included acute ischemic stroke patients with ...

journal_title：Neurology

authors： Ryu DW,Shon YM,Kim BS,Cho AH

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Sleep-disordered breathing (SDB) and respiratory failure (RF) are complications of acid maltase deficiency (AMD), a rare hereditary myopathy. OBJECTIVE:To define the relationship between lung and respiratory muscle function, to establish incidence and patterns of SDB, and to determine daytime predictors of ...

journal_title：Neurology

authors： Mellies U,Ragette R,Schwake C,Baethmann M,Voit T,Teschler H

更新日期：2001-10-09 00:00:00

abstract：BACKGROUND:Attempts at cell-based dopamine replacement therapy in Parkinson disease (PD) have included surgical implantation of adrenal medullary, fetal mesencephalic, and cultured human mesencephalic tissue grafts. Trials involving putamenal implantation of human retinal pigment epithelial (RPE) cells in PD have also ...

journal_title：Neurology

authors： Farag ES,Vinters HV,Bronstein J

更新日期：2009-10-06 00:00:00

abstract：:A 11-year-old boy of short stature had recurrent right temporal pounding headaches of 7 months' duration, and progressive visual loss for 3 days. There was a left hemianopia, alexia without agraphia, and diffuse muscle weakness. Investigation established the presence of a mitochondrial myopathy with pyruvate and lacti...

journal_title：Neurology

authors： Skoglund RR

更新日期：1979-05-01 00:00:00

abstract：OBJECTIVE:To determine the clinical value of JC virus (JCV) detection in various anatomic compartments for the diagnosis of progressive multifocal leukoencephalopathy (PML). METHODS:CSF, peripheral blood mononuclear cells (PBMC), plasma, and urine samples were evaluated from HIV-infected and uninfected individuals. JC...

journal_title：Neurology

authors： Koralnik IJ,Boden D,Mai VX,Lord CI,Letvin NL

更新日期：1999-01-15 00:00:00

abstract：:The malformation of inverse cerebellum and occipital encephalocele is situated morphologically between the Arnold-Chiari and Dandy-Walker malformations. In the three reported cases, hydrocephalus was not present, concomitant malformations of the lamina terminalis were present in two, and polymicrogyria was found in al...

journal_title：Neurology

authors： Smith MT,Huntington HW

更新日期：1977-03-01 00:00:00

abstract：BACKGROUND:Cervical artery dissection is often attributed to an underlying arteriopathy related to a generalized extracellular matrix defect. OBJECTIVE:The authors compared the hemodynamic and morphologic properties of the carotid artery, as assessed noninvasively by ultrasonography, in patients with spontaneous inter...

journal_title：Neurology

authors： Guillon B,Tzourio C,Biousse V,Adraï V,Bousser MG,Touboul PJ

更新日期：2000-09-12 00:00:00

abstract：:Gamma hydroxybutyrate was administered to adult cats by intravenous infusion at varying dosages while an electroencephalogram (EEG) was recorded from electrodes placed stereotactically in the right and left hippocampus and thalamic intralaminar nucleus and from cortical electrodes. Blood cerebrospinal fluid samples we...

journal_title：Neurology

authors： Snead OC 3rd,Yu RK,Huttenlocher PR

更新日期：1976-01-01 00:00:00

abstract：OBJECTIVE:To explore an association with survival of modifying the current standard of care for patients with newly diagnosed glioblastoma of surgery followed by radiotherapy plus concurrent and 6 cycles of maintenance temozolomide chemotherapy (TMZ/RT → TMZ) by extending TMZ beyond 6 cycles. METHODS:The German Glioma...

journal_title：Neurology

authors： Gramatzki D,Kickingereder P,Hentschel B,Felsberg J,Herrlinger U,Schackert G,Tonn JC,Westphal M,Sabel M,Schlegel U,Wick W,Pietsch T,Reifenberger G,Loeffler M,Bendszus M,Weller M

更新日期：2017-04-11 00:00:00

abstract：OBJECTIVE:To assess the evidence demonstrating efficacy, tolerability, and safety of seven new antiepileptic drugs (AEDs) (gabapentin, lamotrigine, topiramate, tiagabine, oxcarbazepine, levetiracetam, and zonisamide) in the treatment of children and adults with refractory partial and generalized epilepsies. METHODS:A ...

journal_title：Neurology

authors： French JA,Kanner AM,Bautista J,Abou-Khalil B,Browne T,Harden CL,Theodore WH,Bazil C,Stern J,Schachter SC,Bergen D,Hirtz D,Montouris GD,Nespeca M,Gidal B,Marks WJ Jr,Turk WR,Fischer JH,Bourgeois B,Wilner A,Faught R

更新日期：2004-04-27 00:00:00

abstract：BACKGROUND:Using a stereologic approach, the density of nerve fibers innervating sweat gland (SG) fragments in patients with diabetes mellitus (DM) and healthy controls using protein gene product (PGP), tyrosine hydroxylase (TH), and vasoactive intestinal peptide (VIP) was measured to determine which marker best detect...

journal_title：Neurology

authors： Liu Y,Billiet J,Ebenezer GJ,Pan B,Hauer P,Wei J,Polydefkis M

更新日期：2015-04-21 00:00:00

abstract：OBJECTIVE:To estimate rate of progression from normal cognition or mild impairment to dementia, and to identify potential risk and protective factors for incident dementia, based on age at dementia onset in a prospective study of a population-based cohort (n = 1,982) aged 65 years and older. METHODS:Following the coho...

journal_title：Neurology

authors： Ganguli M,Lee CW,Snitz BE,Hughes TF,McDade E,Chang CC

更新日期：2015-01-06 00:00:00

abstract：BACKGROUND:Photophobia is an abnormal sensitivity to light experienced by migraineurs during attacks. The pathophysiology of photophobia is poorly understood. Nevertheless, 2 facts appear to have a link with photophobia: visual cortex hyperexcitability on the one hand and interactions between visual pathway and trigemi...

journal_title：Neurology

authors： Denuelle M,Boulloche N,Payoux P,Fabre N,Trotter Y,Géraud G

更新日期：2011-01-18 00:00:00

abstract：:In the wake of dramatic economic success during the past 2 decades, the specialized field of neurology has undergone a significant transformation in China. With an increase in life expectancy, the problems of aging and cognition have grown. Lifestyle alterations have been associated with an epidemiologic transition bo...

journal_title：Neurology

authors： Shi FD,Jia JP

更新日期：2011-11-29 00:00:00

abstract：OBJECTIVE:Since Alzheimer disease (AD) is a slowly progressive disorder and its pathologic features are likely to be present for many years before symptoms become manifest, we investigated whether microstructural white matter changes similar to those identified in patients with AD can be detected in cognitively normal ...

journal_title：Neurology

authors： Zhuang L,Sachdev PS,Trollor JN,Kochan NA,Reppermund S,Brodaty H,Wen W

更新日期：2012-08-21 00:00:00

abstract：:Changes in estrogen levels at menarche, menstruation, pregnancy, and menopause may trigger or change the prevalence of migraine. The fall in estrogen that occurs with menstruation is the trigger for menstrual migraine, whereas the sustained high estrogen levels during pregnancy frequently result in headache relief. Es...

journal_title：Neurology

authors： Silberstein SD

更新日期：1992-03-01 00:00:00

abstract：OBJECTIVE:To identify the genetic and physiologic basis for recessive myasthenic congenital myopathy in 2 families, suggestive of a channelopathy involving the sodium channel gene, SCN4A. METHODS:A combination of whole exome sequencing and targeted mutation analysis, followed by voltage-clamp studies of mutant sodium ...

journal_title：Neurology

authors： Elia N,Palmio J,Castañeda MS,Shieh PB,Quinonez M,Suominen T,Hanna MG,Männikkö R,Udd B,Cannon SC

更新日期：2019-03-26 00:00:00

abstract：:Until 1995, treatment of strokes consisted exclusively of efforts to prevent recurrence. Proof that tissue plasminogen activator is useful for acute management is changing the approach to stroke patients. The development process has been difficult and the current treatment recommendations have been controversial. Rece...

journal_title：Neurology

authors： Zivin JA

更新日期：1999-07-13 00:00:00

abstract：:We present a case of uncontrolled temporal lobe epilepsy due to a focal left temporal neuronal heterotopia associated with the nevoid-basal-cell carcinoma syndrome. This is the first pathologically described lesion associated with temporal lobe epilepsy in this syndrome. Because the patient's seizures resolved after a...

journal_title：Neurology

authors： Hogan RE,Tress B,Gonzales MF,King JO,Cook MJ

更新日期：1996-02-01 00:00:00

abstract：:The authors estimated the sample sizes needed for exploratory trials of MS assessing the efficacy of new treatments in reducing the number of new enhancing lesions vs those of interferon-beta or glatiramer acetate. The sample sizes per arm ranged from 868 (effect: 20%) to 94 (effect: 50%) for patients with relapsing-r...

journal_title：Neurology

authors： Sormani MP,Rovaris M,Bagnato F,Molyneux P,Bruzzi P,Pozzilli C,Miller DH,Comi G,Filippi M

更新日期：2001-11-27 00:00:00