Neuropathological findings in Sneddon's syndrome.

abstract：:In "Dark Victory," released in theaters in 1939, the diagnosis and management of a progressive brain tumor was a central part of the screenplay, and this film marked the beginnings of the depiction of neurologic disease in cinema. Bette Davis' cinematic portrayal of a young woman dying from a brain tumor is close to t...

journal_title：Neurology

authors： Wijdicks EFM

更新日期：2016-04-12 00:00:00

abstract：:A 11-year-old boy of short stature had recurrent right temporal pounding headaches of 7 months' duration, and progressive visual loss for 3 days. There was a left hemianopia, alexia without agraphia, and diffuse muscle weakness. Investigation established the presence of a mitochondrial myopathy with pyruvate and lacti...

journal_title：Neurology

authors： Skoglund RR

更新日期：1979-05-01 00:00:00

abstract：OBJECTIVE:To create and validate a simple, standardized version of the antisaccade (AS) task that requires no specialized equipment for use as a measure of executive function in multicenter clinical studies. METHODS:The bedside AS (BAS) task consisted of 40 pseudorandomized AS trials presented on a laptop computer. BA...

journal_title：Neurology

authors： Hellmuth J,Mirsky J,Heuer HW,Matlin A,Jafari A,Garbutt S,Widmeyer M,Berhel A,Sinha L,Miller BL,Kramer JH,Boxer AL

更新日期：2012-06-05 00:00:00

abstract：:A patient with PD who exhibited disabling tremor and prominent dyskinesia underwent deep brain stimulation (DBS) of the left thalamic ventral intermediate nucleus. The electrode migrated and was replaced but with suboptimal clinical response. Two years later, postmortem analysis found the second electrode tip had ente...

journal_title：Neurology

authors： Henderson JM,O'Sullivan DJ,Pell M,Fung VS,Hely MA,Morris JG,Halliday GM

更新日期：2001-06-12 00:00:00

abstract：OBJECTIVES:To examine associations between 1H magnetic resonance spectroscopic imaging (1H MRSI)-detected hippocampal creatine to N-acetylaspartate (Cr/NAA) ratios and neuropsychological measures sensitive to mesial temporal lobe function. BACKGROUND:The measurement of 1H MRSI-detected hippocampal metabolites has prov...

journal_title：Neurology

authors： Martin RC,Sawrie S,Hugg J,Gilliam F,Faught E,Kuzniecky R

更新日期：1999-12-10 00:00:00

abstract：:The objective of our study was to assess the 5-year risk of and prognostic factors for the development of clinically definite multiple sclerosis (CDMS) following optic neuritis. In a prospective cohort study design, 388 patients, who did not have probable or definite MS at study entry enrolled in the Optic Neuritis Tr...

journal_title：Neurology

authors： Optic Neuritis Study Group.

更新日期：1997-11-01 00:00:00

abstract：:A moderately retarded Japanese boy, with a normal male karyotype (46,XY), was diagnosed to have a subcortical band heterotopia or double cortex syndrome. The band heterotopia was relatively thick compared with that of other patients reported. On T2-weighted coronal MR sections, there were numerous radial linear struct...

journal_title：Neurology

authors： Ono J,Mano T,Andermann E,Harada K,Sakurai K,Ikeda T,Yoshihara N,Shimizu K,Okada S,Andermann F

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:Timely recruiting and retaining participants into Alzheimer disease (AD) clinical trials is a challenge. We used conjoint analysis to identify how alterations in attributes of clinical trial design improve willingness to participate: risk, home visits, car service, or increased chance of receiving interventi...

journal_title：Neurology

authors： Karlawish J,Cary MS,Rubright J,Tenhave T

更新日期：2008-12-02 00:00:00

abstract：BACKGROUND:Over 50% of persons with idiopathic REM sleep behavior disorder (RBD) will develop Parkinson disease (PD) or dementia. At present, there is no way to predict who will develop disease. Since polysomnography is performed in all patients with idiopathic RBD at diagnosis, there is an opportunity to analyze if ba...

journal_title：Neurology

authors： Postuma RB,Gagnon JF,Rompré S,Montplaisir JY

更新日期：2010-01-19 00:00:00

abstract：:Two adult brothers became ill within 48 hours of each other, and both had severe myoglobinuria. One brother died of oliguric renal failure. The other did not have renal failure and survived. Acute influenza A infection was documented serologically and from throat washings in the surviving brother, and by isolation of ...

journal_title：Neurology

authors： Zamkoff K,Rosen N

更新日期：1979-03-01 00:00:00

abstract：:INeuro@neurolist.mcg. edu: An e-mail discussion list for neurologists Neuro@neurolist.mcg.edu (Neurolist) is a discussion list for neurologists. This Internet tool, established in 1994, allows the worldwide community of neurologists to communicate quickly and efficiently using e-mail, web browsers, and newsreaders. Ne...

journal_title：Neurology

authors： Rivner MH

更新日期：1999-06-10 00:00:00

abstract：:Isovaleric acidemia (IVA) is an inborn error of leucine metabolism, resulting in an accumulation of isovaleric acid in the body fluids. The neuropathologic findings in an 11-day-old infant with IVA consisted of diffuse cerebral edema, massive cerebellar hemorrhage, upward transtentorial herniation, and focal degenerat...

journal_title：Neurology

authors： Fischer AQ,Challa VR,Burton BK,McLean WT

更新日期：1981-06-01 00:00:00

abstract：OBJECTIVE:To determine whether metformin is associated with a lower incidence of dementia than sulfonylureas. METHODS:This was a retrospective cohort study of US veterans ≥65 years of age with type 2 diabetes who were new users of metformin or a sulfonylurea and had no dementia. Follow-up began after 2 years of therap...

journal_title：Neurology

authors： Orkaby AR,Cho K,Cormack J,Gagnon DR,Driver JA

更新日期：2017-10-31 00:00:00

abstract：:Methionine-enkephalin, substance P, and homovanillic acid concentrations were measured in the CSF of subjects not affected by neurologic disorders (group 1), and in parkinsonian patients who had a slight or moderate (group 2) or severe (group 3) disability. Homovanillic acid and substance P concentrations in the CSF o...

journal_title：Neurology

authors： Pezzoli G,Panerai AE,Di Giulio A,Longo A,Passerini D,Carenzi A

更新日期：1984-04-01 00:00:00

abstract：:We used single-photon emission computed tomography (SPECT) to study postictal cerebral blood flow (CBF) in 51 patients with temporal lobe epilepsy. There were 78 seizures studied, 77 by early postictal injection of Tc-99m HMPAO (delay from seizure onset = 4.3 +/- 4.5 min) and one by ictal injection. Increased focal te...

journal_title：Neurology

authors： Rowe CC,Berkovic SF,Austin MC,McKay WJ,Bladin PF

更新日期：1991-07-01 00:00:00

abstract：OBJECTIVE:We tested the hypothesis that admission serum magnesium levels are associated with hematoma volume, hematoma growth, and functional outcomes in patients with intracerebral hemorrhage (ICH). METHODS:Patients presenting with spontaneous ICH were enrolled in an observational cohort study that prospectively coll...

journal_title：Neurology

authors： Liotta EM,Prabhakaran S,Sangha RS,Bush RA,Long AE,Trevick SA,Potts MB,Jahromi BS,Kim M,Manno EM,Sorond FA,Naidech AM,Maas MB

更新日期：2017-08-22 00:00:00

abstract：:Juvenile myoclonic epilepsy (JME) is a distinct subform of idiopathic generalized epilepsy of adolescence. Linkage studies with Bf and serologic HLA markers in families of JME patients have shown a tight linkage on chromosome 6. We present a linkage analysis with HLA-DQ restriction fragment length polymorphisms on mor...

journal_title：Neurology

authors： Durner M,Sander T,Greenberg DA,Johnson K,Beck-Mannagetta G,Janz D

更新日期：1991-10-01 00:00:00

abstract：:Although Alzheimer's disease is generally considered a degenerative disease that primarily affects the cerebral cortex, subcortical structures such as the substantia innominata and certain brainstem nuclei may be involved. In 28 patients with progressive dementia and pathologically confirmed Alzheimer's disease, we fo...

journal_title：Neurology

authors： McDuff T,Sumi SM

更新日期：1985-01-01 00:00:00

abstract：:We studied performance on tests of visual neglect and left lateral gaze after caloric stimulation in 18 patients with left-sided visual neglect after strokes. Except for one patient with absent vestibulo-ocular responses, all improved during caloric stimulation on the left by cold (LC) or on the right by warm water (R...

journal_title：Neurology

authors： Rubens AB

更新日期：1985-07-01 00:00:00

abstract：:Three patients presented with unilateral progressive optic neuropathy. None of these patients had signs of symptoms referable to the chiasm or eye, thus confining their decline in vision to the optic nerve. Clinical and neuroradiographic evidence suggested a meningioma involving the optic nerve at the orbital-canalicu...

journal_title：Neurology

authors： Gudeman SK,Selhorst JB,Susac JO,Waybright EA

更新日期：1982-06-01 00:00:00

abstract：:Parinaud syndrome, associated with a left thalamic hemorrhage, disappeared completely in a 57-year-old woman after ventriculoperitoneal shunt. The syndrome may be attributed to increased intracranial pressure owing to mass effect on the pretectal region and tectum, or to tightness in the incisura causing hydrocephalus...

journal_title：Neurology

authors： Waga S,Okada M,Yamamoto Y

更新日期：1979-03-01 00:00:00

abstract：OBJECTIVE:To determine quantitative size thresholds for enlargement of the optic nerve, chiasm, and tract in children with neurofibromatosis type 1 (NF1). METHODS:Children 0.5-18.6 years of age who underwent high-resolution T1-weighted MRI were eligible for inclusion. This consisted of children with NF1 with or withou...

journal_title：Neurology

authors： Avery RA,Mansoor A,Idrees R,Biggs E,Alsharid MA,Packer RJ,Linguraru MG

更新日期：2016-06-14 00:00:00

abstract：BACKGROUND:Mutations in the early growth response 2 (EGR2) gene have recently been found in patients with congenital hypomyelinating neuropathy and Charcot-Marie-Tooth type 1 (CMT1) disease. OBJECTIVE:To determine the frequency of EGR2 mutations in patients with a diagnosis of CMT1, Dejerine-Sottas syndrome (DSS), or ...

journal_title：Neurology

authors： Timmerman V,De Jonghe P,Ceuterick C,De Vriendt E,Löfgren A,Nelis E,Warner LE,Lupski JR,Martin JJ,Van Broeckhoven C

更新日期：1999-06-10 00:00:00

abstract：:The effects of a single oral dose of levodopa administered in a randomized, double-blind, placebo-controlled cross-over design on formation of a motor memory were studied by a training protocol in patients with chronic stroke. Levodopa enhanced the ability of motor training to encode an elementary motor memory relativ...

journal_title：Neurology

authors： Floel A,Hummel F,Breitenstein C,Knecht S,Cohen LG

更新日期：2005-08-09 00:00:00

abstract：:Clinical trials have demonstrated that risk of cardiovascular events may be reduced in patients with stroke, using blood pressure (BP) reduction and statin therapy, independently of the presence of specific risk factors. These results suggest an alternative approach to secondary stroke prevention, focused more on glob...

journal_title：Neurology

authors： Elkind MS

更新日期：2005-07-12 00:00:00

abstract：:The one-and-a-half syndrome is a clinical disorder of extraocular movements characterized by a conjugate horizontal gaze palsy in one direction plus an internuclear ophthalmoplegia in the other. The syndrome is usually due to a single unilateral lesion of the paramedian pontine reticular formation or the abducens nucl...

journal_title：Neurology

authors： Wall M,Wray SH

更新日期：1983-08-01 00:00:00

abstract：:The development of reliable preclinical detection procedures for idiopathic Parkinson's disease may be the fundamental advance required for the establishment of the cause, the natural history, and ultimately, the prevention of this neurodegenerative disorder. The usefulness of these preclinical markers in efforts to b...

journal_title：Neurology

authors： Ellenberg JH

更新日期：1991-05-01 00:00:00

abstract：OBJECTIVE:To detect and quantify lesions of the small-caliber sural nerve (SN) in symptomatic and asymptomatic transthyretin familial amyloid polyneuropathy (TTR-FAP) by high-resolution magnetic resonance neurography (MRN) in correlation with electrophysiologic and histopathologic findings. METHODS:Twenty-five patient...

journal_title：Neurology

authors： Kollmer J,Sahm F,Hegenbart U,Purrucker JC,Kimmich C,Schönland SO,Hund E,Heiland S,Hayes JM,Kristen AV,Röcken C,Pham M,Bendszus M,Weiler M

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:PD was associated with increased mortality before levodopa therapy became available. There have been conflicting reports of PD mortality in the modern era. OBJECTIVE:To assess current mortality rates in a large unselected population receiving treatment for parkinsonism (PKM) followed for up to 6 years. MET...

journal_title：Neurology

authors： Guttman M,Slaughter PM,Theriault ME,DeBoer DP,Naylor CD

更新日期：2001-12-26 00:00:00

abstract：OBJECTIVE:To determine the risk, predictors, and prognosis of independence loss and institutionalization in patients with early Parkinson disease (PD). METHODS:We conducted a prospective population-based 5-year longitudinal study following 189 patients with incident PD and 174 controls matched for age, sex, and comorb...

journal_title：Neurology

authors： Bjornestad A,Tysnes OB,Larsen JP,Alves G

更新日期：2016-10-11 00:00:00