Dopaminergic effects on encoding of a motor memory in chronic stroke.

abstract：:Behavioral testing following division of the corpus callosum has shown that the anterior commissure can transfer information related to visual tasks interhemispherically in nonhuman primates but not in humans. We have found that the ratio of anterior commissure cross-sectional area to total neocortical commissural are...

journal_title：Neurology

authors： Foxman BT,Oppenheim J,Petito CK,Gazzaniga MS

更新日期：1986-11-01 00:00:00

abstract：:One hundred and eight multiple sclerosis (MS) patients and 108 matched controls were studied for antibody levels and cellular immune responses to several viruses. There were significant increases in the mean titers of complement fixation (CF) or hemagglutination inhibition (HI), and complement-mediated cytotoxicity (C...

journal_title：Neurology

authors： Fuccillo DA,Madden DL,Castellano GA,Uhlig L,Traub RG,Mattson J,Krezlewicz A,Sever JL

更新日期：1978-06-01 00:00:00

abstract：OBJECTIVE:To assess longitudinal follow-up of the incidence of multiple sclerosis (MS) through five decades and estimate the prevalence rate in Hordaland County, Norway, on January 1, 2003. METHODS:All patients with MS diagnosed from 1953 to 2003 were identified in the patient records of the Department of Neurology, H...

journal_title：Neurology

authors： Grytten N,Glad SB,Aarseth JH,Nyland H,Midgard R,Myhr KM

更新日期：2006-01-24 00:00:00

abstract：:We conducted an exploratory study of young-onset Parkinson's disease (YOPD) to examine occupational and environmental factors associated with disease risk. This case-control study included 63 YOPD patients (diagnosis on or before age 50); controls (n = 68) were diagnosed with rheumatoid arthritis. Crude odds ratios (O...

journal_title：Neurology

authors： Butterfield PG,Valanis BG,Spencer PS,Lindeman CA,Nutt JG

更新日期：1993-06-01 00:00:00

abstract：:Two patients with neglect for extrapersonal space following right-hemisphere stroke both demonstrated retained ability to attend to the left side of internally generated visual images. The attentional system for extrapersonal space may not be identical to the attentional system for intrapersonal space. ...

journal_title：Neurology

authors： Anderson B

更新日期：1993-01-01 00:00:00

abstract：:We performed proton magnetic resonance spectroscopic imaging (1H-MRSI) in patients with motor neuron disease (MND) to evaluate the distribution and extent of cortical neuron damage or loss as reflected by decreased N-acetyl (NA) to creatine (Cr) resonance intensity ratios. We examined premotor (superior frontal gyrus)...

journal_title：Neurology

authors： Pioro EP,Antel JP,Cashman NR,Arnold DL

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:To assess if multifocal motor neuropathy (MMN) with and MMN without conduction block (CB) are similar or distinct diseases. METHODS:The authors reviewed the clinical features and responses to IV immunoglobulin (IVIg) treatment of patients with MMN with and without CB at diagnosis, after 4 years of follow-up ...

journal_title：Neurology

authors： Delmont E,Azulay JP,Giorgi R,Attarian S,Verschueren A,Uzenot D,Pouget J

更新日期：2006-08-22 00:00:00

abstract：:To study the incidence of abnormalities of the pyruvate (PDH) or ketoglutarate (KGDH) dehydrogenase complexes in patients with spinocerebellar degenerations, we measured the activities of PDH and KGDH in platelet-enriched preparations from the blood of 14 patients. Low PDH was found in 6 of the 14 patients; low KGDH w...

journal_title：Neurology

authors： Kark RA,Rodriguez-Budelli M

更新日期：1979-01-01 00:00:00

abstract：:Ocular motor performance was significantly impaired in familial ataxia patients as compared with normal controls. Ataxic patients showed prolonged saccadic latencies, longer saccadic refixation times, reduced visual tracking performance, and increased hypermetria. Cutoff values were derived and applied to 15 subjects ...

journal_title：Neurology

authors： Hutton JT,Albrecht JW,Kuskowski M,Schut LJ

更新日期：1987-04-01 00:00:00

abstract：OBJECTIVE:Since Alzheimer disease (AD) is a slowly progressive disorder and its pathologic features are likely to be present for many years before symptoms become manifest, we investigated whether microstructural white matter changes similar to those identified in patients with AD can be detected in cognitively normal ...

journal_title：Neurology

authors： Zhuang L,Sachdev PS,Trollor JN,Kochan NA,Reppermund S,Brodaty H,Wen W

更新日期：2012-08-21 00:00:00

abstract：BACKGROUND:Saccades are essential for optimal visual function. Chiari type II malformation (CII) is a congenital anomaly of the cerebellum and brainstem, associated with spina bifida. OBJECTIVE:To investigate the effects of CII on saccades and correlate saccadic parameters with brain MRI measurements. METHODS:Saccade...

journal_title：Neurology

authors： Salman MS,Sharpe JA,Eizenman M,Lillakas L,To T,Westall C,Steinbach MJ,Dennis M

更新日期：2005-06-28 00:00:00

abstract：:Combined infusion of high doses of lidocaine and thiopental in a comatose patient induced major latency and amplitude BAEP changes, which progressed to complete BAEP abolition. Responses returned to normal after drugs were discontinued. EEGs during the episodes showed long-lasting periods of activity suppression, but ...

journal_title：Neurology

authors： García-Larrea L,Artru F,Bertrand O,Pernier J,Mauguière F

更新日期：1988-09-01 00:00:00

abstract：:We sought to determine whether geriatric patients with late-life-onset major depression have more subcortical hyperintensities on MRI and greater cognitive impairment than age-matched geriatric patients with early-life-onset major depression, suggesting that subcortical disease may be etiologic in late-life depression...

journal_title：Neurology

authors： Salloway S,Malloy P,Kohn R,Gillard E,Duffy J,Rogg J,Tung G,Richardson E,Thomas C,Westlake R

更新日期：1996-06-01 00:00:00

abstract：:Permanent paralysis was induced in dogs by a 500 gram centimeter force injury on the spinal cord, and drug treatments were given 1 hour after injury and were continued for 3 days. Dogs were evaluated for 90 days. Isotonic saline or mannitol administration were ineffective in reversing the paralysis. In dogs receiving ...

journal_title：Neurology

authors： De La Torre JC,Johnson CM,Goode DJ,Mullan S

更新日期：1975-06-01 00:00:00

abstract：:X-linked spinal and bulbar muscular atrophy (SBMA) is usually associated with feminization and hypogonadism. We were unable to find androgen receptor (AR) in the scrotal skin of three patients with SBMA, and propose that AR abnormality is the cause of the disease. ...

journal_title：Neurology

authors： Matsuura T,Demura T,Aimoto Y,Mizuno T,Moriwaka F,Tashiro K

更新日期：1992-09-01 00:00:00

abstract：OBJECTIVE:To estimate the US commercially insured multiple sclerosis (MS) annual prevalence from 2008 to 2012. METHODS:The study was a retrospective analysis using PharMetrics Plus, a nationwide claims database for over 42 million covered US representative lives. Annual point prevalence required insurance eligibility ...

journal_title：Neurology

authors： Dilokthornsakul P,Valuck RJ,Nair KV,Corboy JR,Allen RR,Campbell JD

更新日期：2016-03-15 00:00:00

abstract：:Cognitive decline is recognized as a prevalent and debilitating symptom of multiple sclerosis (MS), especially deficits in episodic memory and processing speed. The field aims to (1) incorporate cognitive assessment into standard clinical care and clinical trials, (2) utilize state-of-the-art neuroimaging to more thor...

journal_title：Neurology

authors： Sumowski JF,Benedict R,Enzinger C,Filippi M,Geurts JJ,Hamalainen P,Hulst H,Inglese M,Leavitt VM,Rocca MA,Rosti-Otajarvi EM,Rao S

更新日期：2018-02-06 00:00:00

abstract：:Patients with Parkinson's disease (PD) commonly complain of impaired visual function and difficulty reading, despite normal visual acuity. Although previous studies have evaluated contrast sensitivity, color vision, visuospatial processing, visual hallucinations, and ocular movements, none has systematically evaluated...

journal_title：Neurology

authors： Biousse V,Skibell BC,Watts RL,Loupe DN,Drews-Botsch C,Newman NJ

更新日期：2004-01-27 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of opicapone as add-on to levodopa and the effects of switching from entacapone over 1 year of treatment in patients with fluctuating Parkinson disease. METHODS:After completion of a placebo- and entacapone-controlled double-blind study of opicapone (5, 25, or 50 mg), 495 patien...

journal_title：Neurology

authors： Ferreira JJ,Lees AJ,Poewe W,Rascol O,Rocha JF,Keller B,Soares-da-Silva P

更新日期：2018-05-22 00:00:00

abstract：OBJECTIVES:To study the behavioral and neuroanatomic characteristics of perseverative behavior encountered on a target cancellation task in patients with neglect. METHODS:Motor perseverative behavior during line cancellation task was evaluated retrospectively in 60 patients with left hemispatial neglect from right hem...

journal_title：Neurology

authors： Na DL,Adair JC,Kang Y,Chung CS,Lee KH,Heilman KM

更新日期：1999-05-12 00:00:00

abstract：:Restless legs syndrome (RLS) is a common neurologic disorder whose prevalence has been estimated at 4 to 10% of the general population. Although its pathophysiology remains unknown, dopaminergic mechanisms are believed to play a central role. Furthermore, dopaminergic drugs have shown therapeutic efficacy in various l...

journal_title：Neurology

authors： Garcia-Borreguero D,Odin P,Serrano C

更新日期：2003-09-23 00:00:00

abstract：:We report a woman with a chronic inflammatory myopathy who developed muscle stiffness and dystonic postures of both upper extremities. Electromyography demonstrated that involuntary complex repetitive discharges of muscle caused the posture. Rare cases of dystonic posturing may be of peripheral, and not central system...

journal_title：Neurology

authors： Preston DC,Finkleman RS,Munsat TL

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Evidence linking APOE to myelin repair, neuronal plasticity, and cerebral inflammatory processes suggests that it may be relevant in multiple sclerosis (MS). The purpose of this study was to determine whether the epsilon4 allele of APOE is associated with cognitive deficits in patients with MS. METHOD:Using...

journal_title：Neurology

authors： Ghaffar O,Reis M,Pennell N,O'Connor P,Feinstein A

更新日期：2010-05-18 00:00:00

abstract：OBJECTIVE:To assess cortical inhibitory and excitatory mechanisms in obsessive-compulsive disorder (OCD). BACKGROUND:Transcranial magnetic stimulation (TMS) studies have found decreased neuronal inhibition and a reduced cortical silent period in the primary motor area in Tourette's syndrome, focal dystonia, and other ...

journal_title：Neurology

authors： Greenberg BD,Ziemann U,Corá-Locatelli G,Harmon A,Murphy DL,Keel JC,Wassermann EM

更新日期：2000-01-11 00:00:00

abstract：:In patients with cranial dystonia, we compared the effects of central anticholinergic, peripheral anticholinergic, and placebo treatments in a double-blind crossover study. One of the nine patients who completed the study improved markedly with central anticholinergic therapy. The three treatments were indistinguishab...

journal_title：Neurology

authors： Nutt JG,Hammerstad JP,deGarmo P,Carter J

更新日期：1984-02-01 00:00:00

abstract：:The biochemical hallmark of adult Refsum disease (ARD) is an isolated deficiency in the breakdown of phytanic acid. This usually results from a PHYH gene defect, although some cases have been found to carry a PEX7 defect. We describe the phenotype of such a patient, indistinguishable from that of classic ARD. Hence, w...

journal_title：Neurology

authors： Horn MA,van den Brink DM,Wanders RJ,Duran M,Poll-The BT,Tallaksen CM,Stokke OH,Moser H,Skjeldal OH

更新日期：2007-02-27 00:00:00

abstract：:We measured monoamine metabolites and biopterin in the CSF of 37 patients with dementia of the Alzheimer type (DAT), with or without extrapyramidal signs, and in 14 age-matched healthy controls. Compared with concentrations in DAT and controls, the concentrations of homovanillic acid (HVA) and biopterin were significa...

journal_title：Neurology

authors： Kaye JA,May C,Daly E,Atack JR,Sweeney DJ,Luxenberg JS,Kay AD,Kaufman S,Milstien S,Friedland RP

更新日期：1988-04-01 00:00:00

abstract：OBJECTIVE:To measure changes in psychometric state, neural activation, brain volume (BV), and cerebral metabolite concentrations during treatment of minimal hepatic encephalopathy. METHODS:As proof of principle, 22 patients with well-compensated, biopsy-proven cirrhosis of differing etiology and previous minimal hepat...

journal_title：Neurology

authors： McPhail MJ,Leech R,Grover VP,Fitzpatrick JA,Dhanjal NS,Crossey MM,Pflugrad H,Saxby BK,Wesnes K,Dresner MA,Waldman AD,Thomas HC,Taylor-Robinson SD

更新日期：2013-03-12 00:00:00

abstract：:We attempted to determine whether separable components underlie normal subjects' upward bias in bisecting vertical and radial lines under visual guidance. Twelve normal subjects indicated the midpoint of visually presented lines oriented vertically, radially, and horizontally. We placed directional labels ("TOP" and "...

journal_title：Neurology

authors： Jeerakathil TJ,Kirk A

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVE:To assess the pathophysiologic changes in patients with spontaneous intracranial hypotension (SIH) based on measures of CSF dynamics, and on the duration of symptoms, in a retrospective case-controlled study. METHODS:We included consecutive patients investigated for SIH at our department from January 2012 to...

journal_title：Neurology

authors： Häni L,Fung C,Jesse CM,Ulrich CT,Miesbach T,Cipriani DR,Dobrocky T,Z'Graggen WJ,Raabe A,Piechowiak EI,Beck J

更新日期：2020-07-21 00:00:00