Transient drug-induced abolition of BAEPs in coma.

Abstract:

:Combined infusion of high doses of lidocaine and thiopental in a comatose patient induced major latency and amplitude BAEP changes, which progressed to complete BAEP abolition. Responses returned to normal after drugs were discontinued. EEGs during the episodes showed long-lasting periods of activity suppression, but were never isoelectric. BAEPs are resistant to hypothermia and barbiturates, but must be interpreted cautiously in patients treated with a combination of anesthetic drugs that includes lidocaine.

journal_name

Neurology

journal_title

Neurology

authors

García-Larrea L,Artru F,Bertrand O,Pernier J,Mauguière F

doi

10.1212/wnl.38.9.1487

subject

Has Abstract

pub_date

1988-09-01 00:00:00

pages

1487-9

issue

9

eissn

0028-3878

issn

1526-632X

journal_volume

38

pub_type

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