Chiasmal apoplexy: hemorrhage from a cryptic vascular malformation in the optic chiasm.

abstract：BACKGROUND AND PURPOSE:Resistance to insulin-mediated glucose uptake by peripheral tissues is a cardinal defect in type 2 diabetes mellitus. Insulin resistance is also common among nondiabetic individuals, and may be an important risk factor for stroke in both populations. The authors review the definition, epidemiolog...

journal_title：Neurology

authors： Kernan WN,Inzucchi SE,Viscoli CM,Brass LM,Bravata DM,Horwitz RI

更新日期：2002-09-24 00:00:00

abstract：:We examined correlates of depression in patients whose onset of Parkinson's disease (PD) began before age 55 (early-onset group) compared with patients whose onset was after age 55 (late-onset group). The early-onset group showed a significantly higher frequency of depression than the late-onset group. When both group...

journal_title：Neurology

authors： Starkstein SE,Berthier ML,Bolduc PL,Preziosi TJ,Robinson RG

更新日期：1989-11-01 00:00:00

abstract：:A rare case of solitary CNS chloroma in a patient with chronic granulocytic leukemia (CGL) is described. This appears to be the first reported case of intracranial chloroma in CGL without systemic blastic crisis. ...

journal_title：Neurology

authors： Lysy J,Globus M,Okon E,Polliack A,Chowers I

更新日期：1983-08-01 00:00:00

abstract：OBJECTIVE:To measure changes in psychometric state, neural activation, brain volume (BV), and cerebral metabolite concentrations during treatment of minimal hepatic encephalopathy. METHODS:As proof of principle, 22 patients with well-compensated, biopsy-proven cirrhosis of differing etiology and previous minimal hepat...

journal_title：Neurology

authors： McPhail MJ,Leech R,Grover VP,Fitzpatrick JA,Dhanjal NS,Crossey MM,Pflugrad H,Saxby BK,Wesnes K,Dresner MA,Waldman AD,Thomas HC,Taylor-Robinson SD

更新日期：2013-03-12 00:00:00

abstract：OBJECTIVE:To evaluate the usefulness of a mismatch between the severity of acute clinical manifestations and the diffusion-weighted imaging (DWI) lesion in predicting early stroke outcome and infarct volume. METHODS:One hundred sixty-six patients with a hemispheric ischemic stroke of <12 hours' duration were studied. ...

journal_title：Neurology

authors： Dávalos A,Blanco M,Pedraza S,Leira R,Castellanos M,Pumar JM,Silva Y,Serena J,Castillo J

更新日期：2004-06-22 00:00:00

abstract：OBJECTIVE:Clinical trials of fetal neural tissue transplantation for Huntington disease (HD) have been conducted with variable clinical results. However, no long-term analysis of graft survival and integration has been published. Here, we report the pathologic findings in two patients with HD who died 74 and 79 months ...

journal_title：Neurology

authors： Keene CD,Sonnen JA,Swanson PD,Kopyov O,Leverenz JB,Bird TD,Montine TJ

更新日期：2007-06-12 00:00:00

abstract：:An 18-year-old man had noticed increasing difficulty in walking for 4 years. Examination disclosed spastic paraparesis and posterior column signs suggestive of subacute combined degeneration of the spinal cord. Urinalysis, urinary thin-layer chromatography, and intestinal biopsy disclosed typical cystinuria. Perniciou...

journal_title：Neurology

authors： De Myer W,Gebhard RL

更新日期：1975-10-01 00:00:00

abstract：OBJECTIVE:To characterize the nature and degree of cognitive morbidity in patients with chronic temporal lobe epilepsy compared with healthy control subjects, determine the association between the duration of epilepsy and cognitive morbidity, and ascertain whether there are factors that moderate the association between...

journal_title：Neurology

authors： Oyegbile TO,Dow C,Jones J,Bell B,Rutecki P,Sheth R,Seidenberg M,Hermann BP

更新日期：2004-05-25 00:00:00

abstract：:The authors reviewed the incidence of cancer, repetitive nerve stimulation findings, and response to treatment in 73 patients with Lambert-Eaton myasthenic syndrome. Thirty-one patients (42%) had lung cancer, 29 small cell. Doubling of the compound motor action potential amplitude in three tested distal muscles was se...

journal_title：Neurology

authors： Tim RW,Massey JM,Sanders DB

更新日期：2000-06-13 00:00:00

abstract：OBJECTIVE:To delineate the features of regional cerebral metabolic rate of glucose (CMRglc) in dementia with Lewy bodies (DLB). METHODS:We compared absolute CMRglc in 12 patients with a clinical diagnosis of DLB, 12 patients with a clinical diagnosis of Alzheimer's disease (AD), and 12 normal volunteers (NC), using 18...

journal_title：Neurology

authors： Ishii K,Imamura T,Sasaki M,Yamaji S,Sakamoto S,Kitagaki H,Hashimoto M,Hirono N,Shimomura T,Mori E

更新日期：1998-07-01 00:00:00

abstract：:Hypnic headache has been described in several case reports since 1981 and is regarded as an idiopathic headache disorder. In this review of 71 cases in the literature, the clinical features, neurophysiologic including polysomnographic findings, and treatment procedures are analyzed and the pathophysiology of this cond...

journal_title：Neurology

authors： Evers S,Goadsby PJ

更新日期：2003-03-25 00:00:00

abstract：:To identify clinical and electrophysiologic features related to IV immunoglobulin (IVIg) responsiveness in chronic inflammatory demyelinating polyneuropathy (CIDP), the authors conducted a multicenter study on 312 patients with CIDP (199 responders and 113 nonresponders). Muscle atrophy and decreased compound muscle a...

journal_title：Neurology

authors： Iijima M,Yamamoto M,Hirayama M,Tanaka F,Katsuno M,Mori K,Koike H,Hattori N,Arimura K,Nakagawa M,Yoshikawa H,Hayasaka K,Onodera O,Baba M,Yasuda H,Saito T,Nakazato M,Nakashima K,Kira J,Kaji R,Oka N,Sobue G

更新日期：2005-04-26 00:00:00

abstract：:The authors recruited 19 nonambulant patients with Guillain-Barré syndrome into a pilot, double-blind, randomized, placebo-controlled safety trial of interferon beta 1a (IFN[beta]-1a) (Rebif). Participants received IFN[beta]-1a or placebo subcutaneously three times weekly, 22 microg for the first week and then 44 micr...

journal_title：Neurology

authors： Pritchard J,Gray IA,Idrissova ZR,Lecky BR,Sutton IJ,Swan AV,Willison HJ,Winer JB,Hughes RA

更新日期：2003-11-11 00:00:00

abstract：BACKGROUND:Despite convenience, accessibility, and strong correlation to severity of Alzheimer disease (AD) pathology, medial temporal lobe atrophy (MTA) has not been used as a criterion in the diagnosis of prodromal and probable AD. METHODS:Using a newly validated visual rating system, mean MTA scores of three bilate...

journal_title：Neurology

authors： Duara R,Loewenstein DA,Potter E,Appel J,Greig MT,Urs R,Shen Q,Raj A,Small B,Barker W,Schofield E,Wu Y,Potter H

更新日期：2008-12-09 00:00:00

abstract：OBJECTIVE:To explore the inflammatory processes in the pathogenesis of psychiatric symptoms and the prognostic value of psychiatric comorbidities in multiple sclerosis (MS). METHODS:Four hundred five patients with relapsing-remitting (RR) MS underwent psychiatric evaluation by means of Beck Depression Inventory II (BD...

journal_title：Neurology

authors： Rossi S,Studer V,Motta C,Polidoro S,Perugini J,Macchiarulo G,Giovannetti AM,Pareja-Gutierrez L,Calò A,Colonna I,Furlan R,Martino G,Centonze D

更新日期：2017-09-26 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A number of familial temporal lobe epilepsies (TLE) have been recently recognized. Mutations in LGI1 (leucine-rich, glioma-inactivated 1 gene) have been found in a few families with the syndrome of autosomal dominant partial epilepsy with auditory features (ADPEAF). The authors aimed to determ...

journal_title：Neurology

authors： Berkovic SF,Izzillo P,McMahon JM,Harkin LA,McIntosh AM,Phillips HA,Briellmann RS,Wallace RH,Mazarib A,Neufeld MY,Korczyn AD,Scheffer IE,Mulley JC

更新日期：2004-04-13 00:00:00

abstract：OBJECTIVE:To define potential pathogenic mitochondrial DNA (mtDNA) point mutations in a patient with myoclonus epilepsy with ragged-red fibers (MERRF) syndrome. BACKGROUND:MERRF syndrome is typically associated with point mutations in the mtDNA tRNALys gene. METHODS:We performed morphologic, biochemical, and genetic ...

journal_title：Neurology

authors： Arenas J,Campos Y,Bornstein B,Ribacoba R,Martín MA,Rubio JC,Santorelli FM,Zeviani M,DiMauro S,Garesse R

更新日期：1999-01-15 00:00:00

abstract：OBJECTIVE:To perform a single-center pilot investigation of early hematoma removal in patients with intracerebral hemorrhage (ICH). BACKGROUND:Considerable debate remains regarding the utility of surgical clot evacuation for ICH. METHODS:This was a prospective trial of open craniotomy within 12 hours of ICH symptom o...

journal_title：Neurology

authors： Morgenstern LB,Frankowski RF,Shedden P,Pasteur W,Grotta JC

更新日期：1998-11-01 00:00:00

abstract：:There have been few descriptions of spontaneous epidural hematoma of the spinal cord in children. Duration of symptoms in previous cases has varied from hours to days. We recently evaluated a 6-year-old girl with cord compression from an extradural clot, who complained of thoracic back pain for 3 months before becomin...

journal_title：Neurology

authors： Robertson WC Jr,Lee YE,Edmonson MB

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVE:To evaluate attention deficit in Alzheimer's disease (AD) and its relationship to attention deficits associated with aging and with medications altering alertness. METHODS:Ten patients with probable AD, 10 healthy old controls, and 15 young controls performed a covert orienting of spatial attention task. You...

journal_title：Neurology

authors： Oken BS,Kishiyama SS,Kaye JA,Howieson DB

更新日期：1994-04-01 00:00:00

abstract：:Compressive neuropathy due to tight application of handcuffs occurred in 5 patients. The superficial radial nerve was affected in 8 hands and the median nerve in two. Neurologic deficits persisted as long as 3 years after handcuffing. Nerve conduction studies helped to exclude malingering and other diagnoses. All pati...

journal_title：Neurology

authors： Stone DA,Laureno R

更新日期：1991-01-01 00:00:00

abstract：:Subacute encephalitis, characterized by demyelination, gliosis of the gray and white matter, focal necrosis, microglial nodules, atypical oligodendrocyte nuclei, and multinucleation of cells, was present in 27 of 30 (90%) autopsied patients with acquired immune deficiency syndrome (AIDS) or AIDS-related complex. Subac...

journal_title：Neurology

authors： de la Monte SM,Ho DD,Schooley RT,Hirsch MS,Richardson EP Jr

更新日期：1987-04-01 00:00:00

abstract：:The authors analyzed the association of L-carnitine treatment with hepatic survival in 92 patients with severe, symptomatic, valproate-induced hepatotoxicity. Forty-eight percent of the 42 patients treated with L-carnitine survived, but only 10% of the 50 patients treated solely with aggressive supportive care survive...

journal_title：Neurology

authors： Bohan TP,Helton E,McDonald I,König S,Gazitt S,Sugimoto T,Scheffner D,Cusmano L,Li S,Koch G

更新日期：2001-05-22 00:00:00

abstract：:Cytoplasmic inclusion bodies are found in fibers of superior rectus muscle of the eye. They occur in middle-aged and old individuals dying with various unrelated diseases not affecting muscle and in patients with myotonic dystrophy. With light microscopy they can be observed in fibers with pathologic changes, and with...

journal_title：Neurology

authors： Culebras A,Merk FB

更新日期：1975-05-01 00:00:00

abstract：:We enrolled 11 patients with secondary progressive MS in a randomized single-masked cross-over study of plasma exchange (PE) in combination with azathioprine 2 mg/kg. PE was performed once a week for 4 weeks and thereafter every second week for 20 weeks (14 treatments). Eight patients completed the whole trial, and th...

journal_title：Neurology

authors： Sørensen PS,Wanscher B,Szpirt W,Jensen CV,Ravnborg M,Christiansen P,Schreiber K,Nordenbo A

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to identify risk factors for rupture of unruptured cerebral aneurysms (UCAs) in elderly Japanese patients aged 70 years or older. METHODS:The participants included all patients 70 years of age or older in 3 prospective studies in Japan (the Unruptured Cerebral Aneurysm Study of Jap...

journal_title：Neurology

authors： Hishikawa T,Date I,Tokunaga K,Tominari S,Nozaki K,Shiokawa Y,Houkin K,Murayama Y,Ishibashi T,Takao H,Kimura T,Nakayama T,Morita A,For UCAS Japan and UCAS II Investigators.

更新日期：2015-11-24 00:00:00

abstract：OBJECTIVE:To determine (1) if mortality among patients with idiopathic intracranial hypertension (IIH) enrolled in the Intracranial Hypertension Registry (IHR) is different from that of the general population of the United States and (2) what the leading underlying causes of death are among this cohort. METHODS:Mortal...

journal_title：Neurology

authors： Hermes SM,Miller NR,Waslo CS,Benes SC,Tanne E

更新日期：2020-08-18 00:00:00

abstract：OBJECTIVE:To study the long-term dual inhibitory effects of rivastigmine on acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) in patients with AD. METHODS:Eleven patients with mild AD received rivastigmine for 12 months. Cholinesterase (ChE) activities in the CSF and plasma were assessed colorimetrically. ...

journal_title：Neurology

authors： Darreh-Shori T,Almkvist O,Guan ZZ,Garlind A,Strandberg B,Svensson AL,Soreq H,Hellström-Lindahl E,Nordberg A

更新日期：2002-08-27 00:00:00

abstract：:We describe a 43-year-old neurologically intact patient who reported episodes of diplopia and oscillopsia associated with a right-beating nystagmus and a skew deviation. These symptoms and signs were related to a left posterior epileptic EEG discharge. We suggest that these ocular motor signs derived from an ictal act...

journal_title：Neurology

authors： Galimberti CA,Versino M,Sartori I,Manni R,Martelli A,Tartara A

更新日期：1998-05-01 00:00:00

abstract：:Butyrylcholinesterase is implicated in the pathology of AD. Selective inhibitors increase acetylcholine and improve cognitive function in animal models. In dementia with Lewy bodies, cholinergic activities are more affected than in AD. The authors report a highly significant association between temporal cortex butyryl...

journal_title：Neurology

authors： Perry E,McKeith I,Ballard C

更新日期：2003-06-10 00:00:00