Abstract:
:Butyrylcholinesterase is implicated in the pathology of AD. Selective inhibitors increase acetylcholine and improve cognitive function in animal models. In dementia with Lewy bodies, cholinergic activities are more affected than in AD. The authors report a highly significant association between temporal cortex butyrylcholinesterase activity and the rate of cognitive decline in a prospectively studied, autopsy-confirmed dementia with Lewy bodies series.
journal_name
Neurologyjournal_title
Neurologyauthors
Perry E,McKeith I,Ballard Cdoi
10.1212/01.wnl.0000068336.84399.9esubject
Has Abstractpub_date
2003-06-10 00:00:00pages
1852-3issue
11eissn
0028-3878issn
1526-632Xjournal_volume
60pub_type
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