Effects of botulinum toxin on motor system excitability in patients with writer's cramp.

abstract：:The technique of intrathecal enhancement using metrizamide (Amipaque) combined with CT imaging enables both the morphologic and dynamic (serial) evaluation of the intracranial cerebrospinal fluid pathways. Three distinct metrizamide CT cisternographic patterns (delayed, intermediate, and normal) emerge in pediatric pa...

journal_title：Neurology

authors： Drayer BP,Rosenbaum AE

更新日期：1978-01-01 00:00:00

abstract：:Six neonates with prolonged, intractable seizures were treated with valproic acid (VPA). Each patient had received maximum doses of phenobarbital (greater than 40 micrograms/ml), and five patients received at least two additional anticonvulsants, without success. Seizure activity was controlled in five of six (83%) ca...

journal_title：Neurology

authors： Gal P,Oles KS,Gilman JT,Weaver R

更新日期：1988-03-01 00:00:00

abstract：:Parinaud syndrome, associated with a left thalamic hemorrhage, disappeared completely in a 57-year-old woman after ventriculoperitoneal shunt. The syndrome may be attributed to increased intracranial pressure owing to mass effect on the pretectal region and tectum, or to tightness in the incisura causing hydrocephalus...

journal_title：Neurology

authors： Waga S,Okada M,Yamamoto Y

更新日期：1979-03-01 00:00:00

abstract：:The authors describe a case of neurologic involvement in mild hyperphenylalaninemia (HPA), not due to tetrahydrobiopterin (BH(4)) deficiency, with low levels of monoamine neurotransmitter metabolites in CSF. The combined BH(4)-Phe loading test suggested a BH(4) response, confirmed by clinical improvement after BH(4) t...

journal_title：Neurology

authors： Bonafé L,Blau N,Burlina AP,Romstad A,Güttler F,Burlina AB

更新日期：2001-09-11 00:00:00

abstract：OBJECTIVE:To investigate the prevalence and nature of cognitive changes associated with sporadic amyotrophic lateral sclerosis (ALS) using a large scale study. METHODS:Consecutive patients with sporadic ALS (n = 279) underwent comprehensive neurologic evaluation and neuropsychological testing. Testing data from normal...

journal_title：Neurology

authors： Ringholz GM,Appel SH,Bradshaw M,Cooke NA,Mosnik DM,Schulz PE

更新日期：2005-08-23 00:00:00

abstract：:Proteins from single frozen sections of human muscle were separated by two-dimensional gel electrophoresis and detected by fluorography or Coomassie Blue staining. The major proteins were identical in different normal muscles obtained from either sex at different ages, and in Duchenne and myotonic dystrophy samples. C...

journal_title：Neurology

authors： Giometti CS,Danon MJ,Anderson NG

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND:Semiology is very useful in the diagnosis and classification of seizures. Some clinical signs occur primarily with specific localization-related epilepsies. OBJECTIVE:To evaluate postictal nose-rubbing as a potential diagnostic sign and a potential lateralizing or localizing indicator. METHODS:We reviewed ...

journal_title：Neurology

authors： Geyer JD,Payne TA,Faught E,Drury I

更新日期：1999-03-10 00:00:00

abstract：:INeuro@neurolist.mcg. edu: An e-mail discussion list for neurologists Neuro@neurolist.mcg.edu (Neurolist) is a discussion list for neurologists. This Internet tool, established in 1994, allows the worldwide community of neurologists to communicate quickly and efficiently using e-mail, web browsers, and newsreaders. Ne...

journal_title：Neurology

authors： Rivner MH

更新日期：1999-06-10 00:00:00

abstract：:We describe a 28-year-old woman presenting with hypokalemic myopathy caused by 17alpha-hydroxylase/17,20-lyase deficiency caused by a homozygous mutation consisting of a G-to-C transition in the initiation codon in exon 1 of the CYP17 gene resulting in expression of an enzymatically inactive truncated P450c17 protein....

journal_title：Neurology

authors： Satoh J,Kuroda Y,Nawata H,Yanase T

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Impairment in the central dopaminergic system has been consistently suggested as an etiologic factor in restless legs syndrome (RLS). OBJECTIVE:To investigate a possible role for the MAOA and MAOB genes in RLS using a population-based association study. METHODS:In addition to a dinucleotide repeat located ...

journal_title：Neurology

authors： Desautels A,Turecki G,Montplaisir J,Brisebois K,Sequeira A,Adam B,Rouleau GA

更新日期：2002-07-23 00:00:00

abstract：BACKGROUND:Cerebral microbleeds (CMB) may be indicative of a hemorrhage-prone microangiopathy. OBJECTIVE:To determine if increased numbers of these lesions are predictive of intracerebral hemorrhage (ICH), especially in terms of a distributional association. METHODS:The authors examined consecutively 227 patients wit...

journal_title：Neurology

authors： Lee SH,Bae HJ,Kwon SJ,Kim H,Kim YH,Yoon BW,Roh JK

更新日期：2004-01-13 00:00:00

abstract：OBJECTIVE:To evaluate the frequency and types of change in "self" seen in frontotemporal dementia (FTD) and to determine the relative involvement of the nondominant and dominant frontal and temporal brain regions in FTD patients with or without changes in a sense of self using neuropsychology tests and neuroimaging. B...

journal_title：Neurology

authors： Miller BL,Seeley WW,Mychack P,Rosen HJ,Mena I,Boone K

更新日期：2001-09-11 00:00:00

abstract：:Both mevalonic aciduria, characterized by psychomotor retardation, cerebellar ataxia, recurrent fever attacks, and death in early childhood, and hyper-immunoglobulin D (hyper-IgD) syndrome, with recurrent fever attacks without neurologic symptoms, are caused by a functional deficiency of mevalonate kinase. In a system...

journal_title：Neurology

authors： Simon A,Kremer HP,Wevers RA,Scheffer H,De Jong JG,Van Der Meer JW,Drenth JP

更新日期：2004-03-23 00:00:00

abstract：:A new cerebral disorder, described in three unrelated children, has recognizable clinical, radiologic, and neuropathologic findings. The onset occurs from early infancy to adolescence with slowing of cognitive performance, rare convulsive seizures, and a mixture of extrapyramidal, cerebellar, and pyramidal signs. CT s...

journal_title：Neurology

authors： Labrune P,Lacroix C,Goutières F,de Laveaucoupet J,Chevalier P,Zerah M,Husson B,Landrieu P

更新日期：1996-05-01 00:00:00

abstract：:We studied 15 dystonic patients with positron emission tomography (PET) and (18F)-2-fluoro-2-deoxy-D-glucose (FDG). The group comprised patients with focal (n = 5), multifocal (n = 1), and generalized (n = 4) dystonia as well as patients with hemidystonia (n = 5). The age at onset was during childhood in four, during ...

journal_title：Neurology

authors： Karbe H,Holthoff VA,Rudolf J,Herholz K,Heiss WD

更新日期：1992-08-01 00:00:00

abstract：:Two siblings and a third child exhibited a syndrome of progressive muscular weakness and wasting, closely resembling Werdnig-Hoffmann's disease. Autopsy of one of the siblings and the third child showed nearly total absence of myelin sheaths in the cranial and spinal nerve roots, relative preservation of axons, and no...

journal_title：Neurology

authors： Kasman M,Bernstein L,Schulman S

更新日期：1976-06-01 00:00:00

abstract：OBJECTIVES:To investigate whether severity and progression of periventricular and deep white matter lesions (WML) and lacunar infarcts were associated with progression of brain atrophy. METHODS:Within the SMART-MR study, a prospective cohort on MRI changes in patients with symptomatic atherosclerotic disease, 565 pati...

journal_title：Neurology

authors： Kloppenborg RP,Nederkoorn PJ,Grool AM,Vincken KL,Mali WP,Vermeulen M,van der Graaf Y,Geerlings MI,SMART Study Group.

更新日期：2012-11-13 00:00:00

abstract：OBJECTIVE:To examine the association between body mass index (BMI) and the risk of Parkinson disease (PD). METHODS:Study cohorts included 22,367 Finnish men and 23,439 women 25 to 59 years of age without a history of PD at baseline. Hazards ratios (HRs) of incident PD were estimated for different levels of BMI. RESUL...

journal_title：Neurology

authors： Hu G,Jousilahti P,Nissinen A,Antikainen R,Kivipelto M,Tuomilehto J

更新日期：2006-12-12 00:00:00

abstract：:A seismic shift in our understanding of the ability to diagnose Alzheimer disease (AD) is occurring. For the last several decades, AD has been a clinical-pathologic diagnosis, and this conceptualization of the disease has served the field well. Typically, the clinician would identify a syndrome such as mild cognitive ...

journal_title：Neurology

authors： Petersen RC

更新日期：2018-08-28 00:00:00

abstract：:Four adolescents had basilar migraine, infrequent cerebral seizures, and severe EEG abnormalities. The clinical course was benign, with normal personality, mentation, and neurologic examination. Almost continuous EEG abnormalities, consisting of rhythmic temporo-occipital sharp and slow wave discharges, or generalized...

journal_title：Neurology

authors： Camfield PR,Metrakos K,Andermann F

更新日期：1978-06-01 00:00:00

abstract：:Medical therapy is the mainstay for epilepsy, with most patients well controlled on a single antiepileptic drug (AED). In this non-refractory group, many patients have medication side effects and occasional seizures. Approximately 30% of patients with partial epilepsy and 25% of patients with generalized epilepsy are ...

journal_title：Neurology

authors： Nadkarni S,LaJoie J,Devinsky O

更新日期：2005-06-28 00:00:00

abstract：:Early, intravenous administration of hematin in a patient with acute intermittent porphyria and severe quadriparesis may have produced partial but remarkable improvement of neuropathy, and resulted in simultaneous decline of porphyrin precursors in the blood. Intermittent, biweekly hematin infusions given 1 month afte...

journal_title：Neurology

authors： Bosch EP,Pierach CA,Bossenmaier I,Cardinal R,Thorson M

更新日期：1977-11-01 00:00:00

abstract：:We report a Japanese Becker muscular dystrophy (BMD) patient with occasional myalgia and cramps during normal activity that developed at the age of 28 months. His family history was negative for neuromuscular diseases. Muscle biopsy analyses, including dystrophin immunostaining, disclosed no clinically relevant findin...

journal_title：Neurology

authors： Ishigaki C,Patria SY,Nishio H,Yabe M,Matsuo M

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:To use the large dataset from the Tysabri Outreach: Unified Commitment to Health (TOUCH) program to compare progressive multifocal leukoencephalopathy (PML) risk with natalizumab extended interval dosing (EID) vs standard interval dosing (SID) in patients with multiple sclerosis (MS). METHODS:This retrospect...

journal_title：Neurology

authors： Ryerson LZ,Foley J,Chang I,Kister I,Cutter G,Metzger RR,Goldberg JD,Li X,Riddle E,Smirnakis K,Kasliwal R,Ren Z,Hotermans C,Ho PR,Campbell N

更新日期：2019-10-08 00:00:00

abstract：:Patients with myotonic dystrophy often develop respiratory failure caused by alveolar hypoventilation. Abnormalities in the ventilatory response to hypoxia and hypercapnia may explain this phenomenon. Accordingly, hypoxic and hypercapnic responses were measured in seven patients with myotonic dystrophy who had only mi...

journal_title：Neurology

authors： Carroll JE,Zwillich CW,Weil JV

更新日期：1977-12-01 00:00:00

abstract：OBJECTIVE:We sought cognitive event-related potential (ERP) biomarkers of disease progression and subsequent conversion to dementia in mild cognitive impairment (MCI). BACKGROUND:Two ERP components, the P600 and N400, are sensitive to abnormal episodic/declarative memory and semantic processing. When congruous categor...

journal_title：Neurology

authors： Olichney JM,Taylor JR,Gatherwright J,Salmon DP,Bressler AJ,Kutas M,Iragui-Madoz VJ

更新日期：2008-05-06 00:00:00

abstract：:A 60-year-old patient suffered a lethal hemispheric infarction 3 days after angiographically documented occlusion of the ipsilateral cervical internal carotid artery and while receiving anticoagulant therapy. Pathologic evidence is consistent with embolism from the distal "tail" of a propagated carotid thrombus as the...

journal_title：Neurology

authors： Finklestein S,Kleinman GM,Cuneo R,Baringer JR

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVE:(1)H-MRS studies have shown abnormalities in brain levels of myo-inositol (mI) and N-acetyl aspartate (NAA) in AD, but the relation of these abnormalities with dementia severity was not examined. The authors sought to determine whether altered brain levels of mI and other metabolites occur in mild AD and whet...

journal_title：Neurology

authors： Huang W,Alexander GE,Chang L,Shetty HU,Krasuski JS,Rapoport SI,Schapiro MB

更新日期：2001-08-28 00:00:00

abstract：:Many aging-associated neurologic disorders, including primary malignant brain tumors (MBT), share a common biphasic age-specific mortality rate pattern: initially increasing exponentially with age, and then declining. A modeling study using MBT mortality was conducted to determine if the observed biphasic pattern of M...

journal_title：Neurology

authors： Riggs JE

更新日期：2000-09-26 00:00:00

abstract：OBJECTIVE:To investigate if patterns of CSF biomarkers (T-tau, P-tau, and Abeta42) can predict cognitive progression, outcome of cholinesterase inhibitor (ChEI) treatment, and mortality in Alzheimer disease (AD). METHODS:We included outpatients with AD (n = 151) from a prospective treatment study with ChEI. At baselin...

journal_title：Neurology

authors： Wallin AK,Blennow K,Zetterberg H,Londos E,Minthon L,Hansson O

更新日期：2010-05-11 00:00:00