Pediatric metrizamide CT cisternography: cerebrospinal fluid circulation and hydrocephalus.

abstract：OBJECTIVE:To investigate the feasibility and clinical utility of using passive electrocorticography (ECoG) for online spatial-temporal functional mapping (STFM) of language cortex in patients being monitored for epilepsy surgery. METHODS:We developed and tested an online system that exploits ECoG's temporal resolution...

journal_title：Neurology

authors： Wang Y,Fifer MS,Flinker A,Korzeniewska A,Cervenka MC,Anderson WS,Boatman-Reich DF,Crone NE

更新日期：2016-03-29 00:00:00

abstract：:The levels of plasma free carnitine and ketone bodies have been found to fluctuate inversely in fasting individuals without muscle disease. Circulating short-chain acyl-carnitines paralleled beta-hydroxybutyrate levels. A patient with lipid storage myopathy and muscle carnitine deficiency, and his two daughters, devel...

journal_title：Neurology

authors： DiDonato S,Cornelio F,Storchi G,Rimoldi M

更新日期：1979-06-01 00:00:00

abstract：:Eighty-one percent (47/58) of private-sector neurologists in Colorado responded to a mail survey of practice patterns. We evaluated patient load, degree of principal versus consultative care, and use of neurodiagnostic tests. Broad areas of neurologic education that were perceived to have been lacking during residency...

journal_title：Neurology

authors： Franklin GM,Ringel SP,Nelson LM,DeLapp C

更新日期：1987-02-01 00:00:00

abstract：:IV immunoglobulin therapy can lead to vascular events through increased serum viscosity and possibly other mechanisms. The authors describe the successful use of tissue plasminogen activator in three of four patients who developed cerebral and peripheral arterial thrombosis after treatment with IV immunoglobulin. ...

journal_title：Neurology

authors： Okuda D,Flaster M,Frey J,Sivakumar K

更新日期：2003-06-10 00:00:00

abstract：:Large doses of phenytoin were administered on 159 occasions to 139 adult patients. Most patients had had more than three seizures or were in status epilepticus. Based on response to treatment, patients could be divided into two groups. Those with excellent response (recurrent seizures, 10%; mortality, 1%) included kno...

journal_title：Neurology

authors： Cranford RE,Leppik IE,Patrick B,Anderson CB,Kostick B

更新日期：1979-11-01 00:00:00

abstract：OBJECTIVE:To examine associations of average and change in late-life blood pressure (BP) with cerebrovascular and Alzheimer disease (AD) neuropathology in a large group of decedents followed longitudinally in vivo. METHODS:This clinical-pathologic study was derived from prospective, community-based cohort studies of a...

journal_title：Neurology

authors： Arvanitakis Z,Capuano AW,Lamar M,Shah RC,Barnes LL,Bennett DA,Schneider JA

更新日期：2018-08-07 00:00:00

abstract：BACKGROUND:Bapineuzumab, a humanized anti-amyloid-beta (Abeta) monoclonal antibody for the potential treatment of Alzheimer disease (AD), was evaluated in a multiple ascending dose, safety, and efficacy study in mild to moderate AD. METHODS:The study enrolled 234 patients, randomly assigned to IV bapineuzumab or place...

journal_title：Neurology

authors： Salloway S,Sperling R,Gilman S,Fox NC,Blennow K,Raskind M,Sabbagh M,Honig LS,Doody R,van Dyck CH,Mulnard R,Barakos J,Gregg KM,Liu E,Lieberburg I,Schenk D,Black R,Grundman M,Bapineuzumab 201 Clinical Trial Investigator

更新日期：2009-12-15 00:00:00

abstract：:Four men with evidence of hemiatrophy resulting from early-life hemispheral injury developed unilateral hemiparkinsonism on the side of the hemiatrophy. The parkinsonism began in the fourth decade and has remained unilateral for 5 to 35 years. In all four patients, the parkinsonism was slowly progressive, but the clin...

journal_title：Neurology

authors： Klawans HL

更新日期：1981-05-01 00:00:00

abstract：:We studied the effects of 3-methoxy, 4-hydroxy-phenylalanine (3-OM-dopa) on monoamine turnover, L-3-4-dihydroxy-phenylalanine (L-dopa) reversal of catecholamine depletion induced by alpha-methyl-paratyrosine (alpha-MT), and the passage of L-dopa across the blood-brain barrier of the rat brain. 3-OM-dopa did not affect...

journal_title：Neurology

authors： Gervas JJ,Muradás V,Bazán E,Aguado EG,de Yébenes JG

更新日期：1983-03-01 00:00:00

abstract：OBJECTIVE:To clarify the relationship between depressive symptoms and the clinical and neuropathologic manifestations of dementia. METHODS:In a clinical-pathologic cohort study, 1,764 older persons without cognitive impairment at enrollment completed annual clinical evaluations for a mean of 7.8 years. The evaluations...

journal_title：Neurology

authors： Wilson RS,Capuano AW,Boyle PA,Hoganson GM,Hizel LP,Shah RC,Nag S,Schneider JA,Arnold SE,Bennett DA

更新日期：2014-08-19 00:00:00

abstract：BACKGROUND:Pharmacologic interventions (e.g., beta blockers) and thalamic lesions have failed to alter the pathophysiology of essential tremor (ET) beyond a reduction in tremor amplitude. Deep brain stimulation (DBS) of the ventral intermediate (VIM) nucleus of the thalamus successfully reduces tremor rating scores. It...

journal_title：Neurology

authors： Vaillancourt DE,Sturman MM,Verhagen Metman L,Bakay RA,Corcos DM

更新日期：2003-10-14 00:00:00

abstract：:Patients with symptomatic > or = 60% (n = 134), asymptomatic > or = 80% (n = 143), and asymptomatic progressive > or = 60% (n = 25) internal carotid artery stenosis underwent stenting and were followed clinically and by Doppler-assisted duplex imaging for 27.1 +/- 15.6 months. Stroke and death from stroke occurred wit...

journal_title：Neurology

authors： Bibl D,Lampl C,Biberhofer I,Kerschner K,Kypta A,Bergmann J,Kaindlstorfer A,Röper C,Yazdi K,Engleder C,Hofmann R,Deibl M,Leisch F,Ransmayr G

更新日期：2005-07-12 00:00:00

abstract：:Homolateral ataxia and crural paresis is a recognized vascular syndrome. However, confirmation of the causative lesion rests principally on one earlier case with multiple other infarcts. We studied a patient with the clinical syndrome; computerized tomography revealed a lucency that appeared within 1 week of the infar...

journal_title：Neurology

authors： Perman GP,Racy A

更新日期：1980-09-01 00:00:00

abstract：OBJECTIVE:To characterize the prevalence and prognostic significance of major driver molecular alterations in adult midline diffuse gliomas (MLG). METHODS:Adults with histologically proven MLG diagnosed between 1996 and 2017 were identified from our tumor bank, systematically reviewed, and reclassified according to WH...

journal_title：Neurology

authors： Picca A,Berzero G,Bielle F,Touat M,Savatovsky J,Polivka M,Trisolini E,Meunier S,Schmitt Y,Idbaih A,Hoang-Xuan K,Delattre JY,Mokhtari K,Di Stefano AL,Sanson M

更新日期：2018-06-05 00:00:00

abstract：:Transcranial Doppler examinations (TCD) of 24 brain-dead adult patients demonstrated persistent movement of blood within the middle cerebral arteries in 21. The characteristic pattern of Doppler shift frequencies, seen in 14, was a sharply contoured, brief anterograde systolic envelope with reversed diastolic flow. Fi...

journal_title：Neurology

authors： Ropper AH,Kehne SM,Wechsler L

更新日期：1987-11-01 00:00:00

abstract：OBJECTIVE:To estimate rates, predictors, and prognostic importance of recanalization in an unselected series of patients with stroke treated with IV thrombolysis. METHODS:We performed a CT angiography or transcranial Doppler (TCD) follow-up examination 24 hours after IV thrombolysis in 64 patients with documented occl...

journal_title：Neurology

authors： Zangerle A,Kiechl S,Spiegel M,Furtner M,Knoflach M,Werner P,Mair A,Wille G,Schmidauer C,Gautsch K,Gotwald T,Felber S,Poewe W,Willeit J

更新日期：2007-01-02 00:00:00

abstract：OBJECTIVES:To study the effects of head injury on disease progression and on neuropathologic outcomes in amyotrophic lateral sclerosis (ALS). METHODS:Patients with ALS were surveyed to obtain head injury history, and medical records were reviewed. Linear regression was performed to determine if head injury was a predi...

journal_title：Neurology

authors： Fournier CN,Gearing M,Upadhyayula SR,Klein M,Glass JD

更新日期：2015-04-28 00:00:00

abstract：OBJECTIVE:To demonstrate noninvasive localization of cognitive cortical areas involved in language processing with magnetoencephalography (MEG) interpreted by multiresolution FOCUSS (MR-FOCUSS), a current density imaging technique. METHOD:MEG data were collected during verb-generation and picture-naming tasks from 18 ...

journal_title：Neurology

authors： Bowyer SM,Moran JE,Mason KM,Constantinou JE,Smith BJ,Barkley GL,Tepley N

更新日期：2004-06-22 00:00:00

abstract：:Thyrotropin-releasing hormone has been reported to increase strength in patients with amyotrophic lateral sclerosis (ALS). DN-1417 is an analog of thyrotropin-releasing hormone, which has less endocrinologic activity, but more anterior horn cell stimulating effect (with no "autorefractory state"). However, 2 mg DN-141...

journal_title：Neurology

authors： Hawley RJ,Kratz R,Goodman RR,McCutchen CB,Sirdofsky M,Hanson PA

更新日期：1987-04-01 00:00:00

abstract：OBJECTIVE:To describe a clinical syndrome of cerebellar ataxia associated with muscle coenzyme Q10 (CoQ10) deficiency. BACKGROUND:Muscle CoQ10 deficiency has been reported only in a few patients with a mitochondrial encephalomyopathy characterized by 1) recurrent myoglobinuria; 2) brain involvement (seizures, ataxia, ...

journal_title：Neurology

authors： Musumeci O,Naini A,Slonim AE,Skavin N,Hadjigeorgiou GL,Krawiecki N,Weissman BM,Tsao CY,Mendell JR,Shanske S,De Vivo DC,Hirano M,DiMauro S

更新日期：2001-04-10 00:00:00

abstract：:We review adjunctive ketogenic diet (KD) and modified Atkins diet (MAD) treatment of refractory epilepsy in adults. Only a few studies have been published, all open-label. Because of the disparate, uncontrolled nature of the studies, we analyzed all studies individually, without a meta-analysis. Across all studies, 32...

journal_title：Neurology

authors： Klein P,Tyrlikova I,Mathews GC

更新日期：2014-11-18 00:00:00

abstract：:We studied a family with an extrapyramidal disorder characterized by childhood onset of lower-limb and axial dystonia, followed by parkinsonism. Dramatic response to levodopa therapy and minimal progression in adult life was seen. The family included five generations of affected members of both sexes in an autosomal d...

journal_title：Neurology

authors： Nygaard TG,Duvoisin RC

更新日期：1986-11-01 00:00:00

abstract：:The authors identified a novel mtDNA mutation (T9176G) in the ATPase 6 gene in a family in which a 10-year-old girl had a severe neurodegenerative disorder, her elder sister had died of Leigh syndrome (LS), and a maternal uncle had a spinocerebellar disorder. Biochemical studies disclosed a reduced rate of ATP synthes...

journal_title：Neurology

authors： Carrozzo R,Tessa A,Vázquez-Memije ME,Piemonte F,Patrono C,Malandrini A,Dionisi-Vici C,Vilarinho L,Villanova M,Schägger H,Federico A,Bertini E,Santorelli FM

更新日期：2001-03-13 00:00:00

abstract：BACKGROUND:Using a stereologic approach, the density of nerve fibers innervating sweat gland (SG) fragments in patients with diabetes mellitus (DM) and healthy controls using protein gene product (PGP), tyrosine hydroxylase (TH), and vasoactive intestinal peptide (VIP) was measured to determine which marker best detect...

journal_title：Neurology

authors： Liu Y,Billiet J,Ebenezer GJ,Pan B,Hauer P,Wei J,Polydefkis M

更新日期：2015-04-21 00:00:00

abstract：OBJECTIVE:To develop and evaluate a model for staging cortical amyloid deposition using PET with high generalizability. METHODS:Three thousand twenty-seven individuals (1,763 cognitively unimpaired [CU], 658 impaired, 467 with Alzheimer disease [AD] dementia, 111 with non-AD dementia, and 28 with missing diagnosis) fr...

journal_title：Neurology

authors： Collij LE,Heeman F,Salvadó G,Ingala S,Altomare D,de Wilde A,Konijnenberg E,van Buchem M,Yaqub M,Markiewicz P,Golla SSV,Wottschel V,Wink AM,Visser PJ,Teunissen CE,Lammertsma AA,Scheltens P,van der Flier WM,Boellaard R

更新日期：2020-09-15 00:00:00

abstract：OBJECTIVE:To ascertain the prevalence and determinants of neuropathy in patients with Parkinson disease (PD), in particular, the roles of vitamin B12 and levodopa exposure. METHODS:We performed a cross-sectional study of 37 patients with PD and 37 age- and gender-matched controls, using a sensitive and validated neuro...

journal_title：Neurology

authors： Rajabally YA,Martey J

更新日期：2011-11-29 00:00:00

abstract：:To determine the frequency of subjective sleep problems in spinocerebellar ataxia type 6 (SCA6), the authors surveyed 25 patients and 25 age-matched controls with the Epworth Sleepiness Scale (ESS) and Pittsburgh Sleep Quality Index (PSQI). The ESS was higher in patients with SCA6 (9.12 +/- 5.80; CI: 2.28) than in con...

journal_title：Neurology

authors： Howell MJ,Mahowald MW,Gomez CM

更新日期：2006-05-09 00:00:00

abstract：OBJECTIVE:Utilization of postacute care is associated with improved poststroke outcomes. However, more than 20% of American adults under age 65 are uninsured. We sought to determine whether insurance status is associated with utilization and intensity of institutional postacute care among working age stroke survivors. ...

journal_title：Neurology

authors： Skolarus LE,Meurer WJ,Burke JF,Prvu Bettger J,Lisabeth LD

更新日期：2012-05-15 00:00:00

abstract：OBJECTIVE:To describe the phenotype and phenotype-genotype correlations in patients with amyotrophic lateral sclerosis (ALS) with TARDBP gene mutations. METHODS:French TARDBP+ patients with ALS (n = 28) were compared first to 3 cohorts: 737 sporadic ALS (SALS), 192 nonmutated familial ALS (FALS), and 58 SOD1 + FALS, a...

journal_title：Neurology

authors： Corcia P,Valdmanis P,Millecamps S,Lionnet C,Blasco H,Mouzat K,Daoud H,Belzil V,Morales R,Pageot N,Danel-Brunaud V,Vandenberghe N,Pradat PF,Couratier P,Salachas F,Lumbroso S,Rouleau GA,Meininger V,Camu W

更新日期：2012-05-08 00:00:00

abstract：OBJECTIVE:This study assessed the tissue integrity of major cervical cord tracts by using diffusion tensor imaging (DTI) to determine the relationship with specific clinical functions carried by those tracts. METHODS:This was a cross-sectional study of 37 patients with multiple sclerosis or neuromyelitis optica with r...

journal_title：Neurology

authors： Naismith RT,Xu J,Klawiter EC,Lancia S,Tutlam NT,Wagner JM,Qian P,Trinkaus K,Song SK,Cross AH

更新日期：2013-06-11 00:00:00