Intravenous phenytoin in acute treatment of seizures.

Abstract:

:Large doses of phenytoin were administered on 159 occasions to 139 adult patients. Most patients had had more than three seizures or were in status epilepticus. Based on response to treatment, patients could be divided into two groups. Those with excellent response (recurrent seizures, 10%; mortality, 1%) included known epileptics with exacerbation of seizures (n = 75), atypical alcohol withdrawal (6), or miscellaneous conditions (17). Those with poor results (recurrent seizures, 57% mortality, 38%) included patients with anoxic or metabolic encephalopathy (14), stroke or other vascular disease (14), brain tumor (5), or trauma (5).

journal_name

Neurology

journal_title

Neurology

authors

Cranford RE,Leppik IE,Patrick B,Anderson CB,Kostick B

doi

10.1212/wnl.29.11.1474

subject

Has Abstract

pub_date

1979-11-01 00:00:00

pages

1474-9

issue

11

eissn

0028-3878

issn

1526-632X

journal_volume

29

pub_type

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