Familial 'sleep apnea plus' syndrome: report of a family.

abstract：:We report two patients with unique homonymous hemianopias from occipital lobe infarctions. One patient had vertical meridian sparing, and the other displayed horizontal meridian sparing. MRI correlation with the visual field defects confirmed that the vertical hemianopic meridian was represented along the border of th...

journal_title：Neurology

authors： Gray LG,Galetta SL,Schatz NJ

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact of early blood pressure (BP) changes on diffusion-weighted imaging (DWI) lesion evolution and clinical outcome in patients with stroke treated with IV tissue plasminogen activator (tPA). METHODS:We prospectively evaluated 80 patients with stroke with a documented middle cerebral artery...

journal_title：Neurology

authors： Delgado-Mederos R,Ribo M,Rovira A,Rubiera M,Munuera J,Santamarina E,Delgado P,Maisterra O,Alvarez-Sabin J,Molina CA

更新日期：2008-08-19 00:00:00

abstract：:This is a case study of a patient with the clinical diagnosis of meningoencephalitis. It demonstrates the in vivo development of plasma cells in the central nervous system. All the stages of in vitro mitogen-induced lymphocyte transformation previously described by light and electron microscopy are recapitulated in th...

journal_title：Neurology

authors： Glasser L,Payne C,Corrigan JJ Jr

更新日期：1977-05-01 00:00:00

abstract：:Trigeminal neuralgia is an uncommon but troublesome symptom of multiple sclerosis that can be refractory to conventional treatments. Misoprostol, a long-acting prostaglandin E1 analogue, relieved pain in six of seven patients who had failed to respond to conventional pharmacologic therapy. ...

journal_title：Neurology

authors： Reder AT,Arnason BG

更新日期：1995-06-01 00:00:00

abstract：:A patient presented with bilateral brachial plexus neuropathy which 2 weeks later evolved into a polyneuropathy involving all four extremities. On further investigation, the patient was found to have systemic lupus erythematosus. Treatment with steroids was accompanied by complete resolution of the neurologic findings...

journal_title：Neurology

authors： Bloch SL,Jarrett MP,Swerdlow M,Grayzel AI

更新日期：1979-12-01 00:00:00

abstract：:In four patients who received periocular injections of botulinum toxin for blepharospasm, abnormal neuromuscular transmission was demonstrated by single-fiber EMG in arm muscles. The time course with which the abnormalities developed and cleared, as well as the inverse relationship between the neuromuscular jitter and...

journal_title：Neurology

authors： Sanders DB,Massey EW,Buckley EG

更新日期：1986-04-01 00:00:00

abstract：BACKGROUND:Muscle channelopathies such as paramyotonia, hyperkalemic periodic paralysis, and potassium-aggravated myotonia are caused by gain-of-function Na+ channel mutations. METHODS:Methods: Implementation of a three-dimensional radial 23Na magnetic resonance (MR) sequence with ultra-short echo times allowed the au...

journal_title：Neurology

authors： Weber MA,Nielles-Vallespin S,Essig M,Jurkat-Rott K,Kauczor HU,Lehmann-Horn F

更新日期：2006-10-10 00:00:00

abstract：:Migraine is associated with stimulus hypersensitivity, increased evoked cortical responses, and abnormal 5-HT levels in peripheral blood. We studied cortical auditory evoked potentials (AEPs) between attacks in 35 patients suffering from migraine without aura (MO, n = 25) or with aura (MA, n = 10) and in 25 healthy vo...

journal_title：Neurology

authors： Wang W,Timsit-Berthier M,Schoenen J

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:To assess the onset of ocrelizumab efficacy on brain MRI measures of disease activity in the phase II study in relapsing-remitting multiple sclerosis (RRMS), and relapse rate in the pooled phase III studies in relapsing multiple sclerosis (RMS). METHODS:Brain MRI activity was determined in the phase II trial...

journal_title：Neurology

authors： Barkhof F,Kappos L,Wolinsky JS,Li DKB,Bar-Or A,Hartung HP,Belachew S,Han J,Julian L,Sauter A,Napieralski J,Koendgen H,Hauser SL

更新日期：2019-11-05 00:00:00

abstract：OBJECTIVE:To examine the genetic relationships among epilepsies with different seizure types--myoclonic, absence, and generalized tonic-clonic--within the idiopathic generalized epilepsies (IGEs). BACKGROUND:Careful phenotype definition in the epilepsies may allow division into groups that share susceptibility genes. ...

journal_title：Neurology

authors： Winawer MR,Marini C,Grinton BE,Rabinowitz D,Berkovic SF,Scheffer IE,Ottman R

更新日期：2005-08-23 00:00:00

abstract：OBJECTIVE:To use the Unified Batten Disease Rating Scale (UBDRS) to measure the rate of decline in physical and functional capability domains in patients with juvenile neuronal ceroid lipofuscinosis (JNCL) or Batten disease, a neurodegenerative lysosomal storage disorder. We have evaluated the UBDRS in subjects with JN...

journal_title：Neurology

authors： Kwon JM,Adams H,Rothberg PG,Augustine EF,Marshall FJ,Deblieck EA,Vierhile A,Beck CA,Newhouse NJ,Cialone J,Levy E,Ramirez-Montealegre D,Dure LS,Rose KR,Mink JW

更新日期：2011-11-15 00:00:00

abstract：:Weight loss is common in Alzheimer's disease (AD), but its pathogenesis is poorly understood. It is unclear whether an elevated daily energy expenditure contributes to the weight loss. We tested the hypothesis that daily energy expenditure is higher in AD patients compared to healthy elderly. Thirty AD (73 +/- 8 years...

journal_title：Neurology

authors： Poehlman ET,Toth MJ,Goran MI,Carpenter WH,Newhouse P,Rosen CJ

更新日期：1997-04-01 00:00:00

abstract：:A 60-year-old patient suffered a lethal hemispheric infarction 3 days after angiographically documented occlusion of the ipsilateral cervical internal carotid artery and while receiving anticoagulant therapy. Pathologic evidence is consistent with embolism from the distal "tail" of a propagated carotid thrombus as the...

journal_title：Neurology

authors： Finklestein S,Kleinman GM,Cuneo R,Baringer JR

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence and clinical effect of ophthalmologic symptoms in patients with Parkinson disease (PD), compared with controls, using a standardized questionnaire. METHODS:In this observational, cross-sectional, multicenter study, 848 patients with PD and 250 healthy controls completed the Visual...

journal_title：Neurology

authors： Borm CDJM,Visser F,Werkmann M,de Graaf D,Putz D,Seppi K,Poewe W,Vlaar AMM,Hoyng C,Bloem BR,Theelen T,de Vries NM

更新日期：2020-04-07 00:00:00

abstract：OBJECTIVE:This study aims to evaluate protective effects of brief repetitive bilateral arm ischemic preconditioning (BAIPC) on stroke recurrence in patients with symptomatic atherosclerotic intracranial arterial stenosis (IAS). METHODS:A total of 68 consecutive cases with symptomatic IAS, diagnosed by imaging, were en...

journal_title：Neurology

authors： Meng R,Asmaro K,Meng L,Liu Y,Ma C,Xi C,Li G,Ren C,Luo Y,Ling F,Jia J,Hua Y,Wang X,Ding Y,Lo EH,Ji X

更新日期：2012-10-30 00:00:00

abstract：:Several recent autopsy studies suggest that senile dementia of Lewy body type (SDLT) may be the second most common neuropathologic cause of dementia in the elderly, accounting for 7 to 30% of all cases. Operational criteria for the antemortem clinical diagnosis of SDLT have already been proposed by our group. The perf...

journal_title：Neurology

authors： McKeith IG,Fairbairn AF,Bothwell RA,Moore PB,Ferrier IN,Thompson P,Perry RH

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Genetic studies of PD frequently rely on family history interviews (FHI), yet the accuracy of data obtained in this way is unclear. OBJECTIVE:To assess the interinformant reliability and validity of family history information on PD in first-degree relatives of PD cases and controls. METHODS:A structured FH...

journal_title：Neurology

authors： Marder K,Levy G,Louis ED,Mejia-Santana H,Cote L,Andrews H,Harris J,Waters C,Ford B,Frucht S,Fahn S,Ottman R

更新日期：2003-07-08 00:00:00

abstract：:Between the years 1964 and 1973, 225 patients with transient ischemic attacks (TIAs) due primarily to atherosclerosis were evaluated and treated. They have now been followed for from 3 to 14 years (average 5.5 years). As of 1976, 82 of the 225 patients were dead, 21 from cerebral infarction, 52 from heart disease and ...

journal_title：Neurology

authors： Toole JF,Yuson CP,Janeway R,Johnston F,Davis C,Cordell AR,Howard G

更新日期：1978-08-01 00:00:00

abstract：OBJECTIVE:We sought to assess the prevalence, correlates, and consequences of periodic limb movements of sleep (PLMS) in persons with obstructive sleep apnea (OSA) and the effect (worsening or improvement) of continuous positive airway pressure (CPAP) therapy on PLMS in a large prospective multicenter randomized contro...

journal_title：Neurology

authors： Budhiraja R,Javaheri S,Pavlova MK,Epstein LJ,Omobomi O,Quan SF

更新日期：2020-04-28 00:00:00

abstract：:We studied lymphocyte subsets and major histocompatibility complex (MHC) class II antigens in frozen brain tissues from three patients with subacute sclerosing panencephalitis (SSPE) using immunocytochemical techniques. Perivascular cuffs consisted predominantly of T cells and MHC class II-positive cells. In the paren...

journal_title：Neurology

authors： Nagano I,Nakamura S,Yoshioka M,Kogure K

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVE:There is only limited evidence from adequately controlled clinical trials to support high-dose methylprednisolone therapy for attacks of multiple sclerosis (MS) and none supporting oral administration. We assessed the effect of oral high-dose methylprednisolone therapy in attacks of MS. METHODS:Twenty-five p...

journal_title：Neurology

authors： Sellebjerg F,Frederiksen JL,Nielsen PM,Olesen J

更新日期：1998-08-01 00:00:00

abstract：:This manuscript provides a practical summary of guidelines for institution of apomorphine subcutaneous injectable therapy, including patient education, pre-treatment issues, dosage titration and side-effect care. The timing of each injection is crucial if an impending "off" period is to be averted. Patients need to be...

journal_title：Neurology

authors： Bowron A

更新日期：2004-03-23 00:00:00

abstract：OBJECTIVE:(1)H-MRS studies have shown abnormalities in brain levels of myo-inositol (mI) and N-acetyl aspartate (NAA) in AD, but the relation of these abnormalities with dementia severity was not examined. The authors sought to determine whether altered brain levels of mI and other metabolites occur in mild AD and whet...

journal_title：Neurology

authors： Huang W,Alexander GE,Chang L,Shetty HU,Krasuski JS,Rapoport SI,Schapiro MB

更新日期：2001-08-28 00:00:00

abstract：:Spinal epidural lipomatosis (SEL) is a rare complication of iatrogenic Cushing's syndrome (CS). There is only one case reported of symptomatic SEL in association with endogenous CS. We present a patient with compressive myeloradiculopathy due to SEL and Cushing's disease and suggest that in SEL of hypercortisolism, th...

journal_title：Neurology

authors： Sivakumar K,Sheinart K,Lidov M,Cohen B

更新日期：1995-12-01 00:00:00

abstract：:Rates of temporal horn volume change were significantly greater in the subjects with mild cognitive impairment who were developing dementia vs those who remained stable. ...

journal_title：Neurology

authors： Erten-Lyons D,Howieson D,Moore MM,Quinn J,Sexton G,Silbert L,Kaye J

更新日期：2006-01-24 00:00:00

abstract：:We tested the efficacy of coenzyme Q10 (ubidecarenone, CoQ10) therapy in patients with Kearns-Sayre syndrome and other mitochondrial myopathies with chronic progressive external ophthalmoplegia (CPEO). We treated seven patients for 1 year with daily oral administration of 120 mg of CoQ10. Throughout the treatment most...

journal_title：Neurology

authors： Bresolin N,Bet L,Binda A,Moggio M,Comi G,Nador F,Ferrante C,Carenzi A,Scarlato G

更新日期：1988-06-01 00:00:00

abstract：:Rapsyn mutations in 16 unrelated patients with a congenital/hereditary myasthenic syndrome were identified, and a mutation (N88K) common to each of them was found. Two distinct phenotypes were noted: early and late onset. The former is frequently associated with arthrogryposis multiplex congenita and life-threatening ...

journal_title：Neurology

authors： Burke G,Cossins J,Maxwell S,Owens G,Vincent A,Robb S,Nicolle M,Hilton-Jones D,Newsom-Davis J,Palace J,Beeson D

更新日期：2003-09-23 00:00:00

abstract：OBJECTIVE:We developed the Recurrence and Recovery Questionnaire (RRQ) by converting the Pediatric Stroke Outcome Measure (PSOM) to a questionnaire for telephone interview and sought to validate the RRQ in a large cohort. METHOD:We analyzed parents' RRQ responses and same-day PSOM assessments for 232 children who had ...

journal_title：Neurology

authors： Lo WD,Ichord RN,Dowling MM,Rafay M,Templeton J,Halperin A,Smith SE,Licht DJ,Moharir M,Askalan R,Deveber G,International Pediatric Stroke Study (IPSS) Investigators.

更新日期：2012-08-28 00:00:00

abstract：OBJECTIVE:To evaluate the occurrence, treatment, and outcome of subdural empyema complicating community-acquired bacterial meningitis in adults. METHODS:Case series from a prospective nationwide cohort study from Dutch hospitals from 2006 to 2011. RESULTS:Subdural empyema was diagnosed in 28 of 1,034 episodes (2.7%),...

journal_title：Neurology

authors： Jim KK,Brouwer MC,van der Ende A,van de Beek D

更新日期：2012-11-20 00:00:00

abstract：BACKGROUND:Deep brain stimulation of the internal global pallidus (GPi) and the subthalamic nucleus (STN) has become a treatment alternative in advanced PD. Although the effects of GPi stimulation have been examined recently, little is known about STN stimulation effects on motor cortex excitability. METHODS:The effec...

journal_title：Neurology

authors： Däuper J,Peschel T,Schrader C,Kohlmetz C,Joppich G,Nager W,Dengler R,Rollnik JD

更新日期：2002-09-10 00:00:00