Botulinum toxin for blepharospasm: single-fiber EMG studies.

abstract：:We report a patient with rostral hypothalamic damage that significantly disrupted temporal patterning of the sleep-wake cycle, body temperature, and cognitive and behavioral functioning. The findings suggest that the suprachiasmatic region of the hypothalamus is important for the circadian control of human behavior, a...

journal_title：Neurology

authors： Cohen RA,Albers HE

更新日期：1991-05-01 00:00:00

abstract：:From 536 patients with the CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasis), seven were identified as having peripheral neuropathy not attributable to another cause. Peripheral neuropathy developed 0 to 25 years after their first symptoms of scleroderma. Unex...

journal_title：Neurology

authors： Dyck PJ,Hunder GG,Dyck PJ

更新日期：1997-12-01 00:00:00

abstract：:This study was undertaken to determine the amount and histologic appearance of the persistent thymic tissue removed post mortem from 20 patients over 60 years of age with myasthenia gravis. One patient died several days after thymectomy. No recognizable thymic tissue on gross examination was seen in any patient. On mi...

journal_title：Neurology

authors： Perlo VP,Arnason B,Castleman B

更新日期：1975-03-01 00:00:00

abstract：:A new generation of Atraumatic (blunt tipped) needles now exists in addition to the traditional Quincke (cutting tip) needles for LP. We wished to identify the optimal size and type of needle that should be used for this technique. Requirements include rapid and accurate transduction of CSF pressure and adequate flow ...

journal_title：Neurology

authors： Carson D,Serpell M

更新日期：1996-07-01 00:00:00

abstract：:We studied six patients with the clinical, sonographic, CT, and biochemical profile of minimal euthyroid Graves' disease (MEGD). This syndrome was characterized clinically by small but obtrusive and measurable amounts of diplopia related to endocrine ophthalmopathy and the conspicuous absence of systemic or laboratory...

journal_title：Neurology

authors： Spector RH,Carlisle JA

更新日期：1987-11-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to perform a third cognitive assessment in our pediatric-onset multiple sclerosis (MS) patient cohort and determine predictors of the individual cognitive outcome. METHODS:After 4.7 ± 0.7 years from baseline evaluation, 48 of 63 patients in the original cohort were reassessed on an e...

journal_title：Neurology

authors： Amato MP,Goretti B,Ghezzi A,Hakiki B,Niccolai C,Lori S,Moiola L,Falautano M,Viterbo RG,Patti F,Cilia S,Pozzilli C,Bianchi V,Roscio M,Martinelli V,Comi G,Portaccio E,Trojano M,MS Study Group of the Italian Neurological

更新日期：2014-10-14 00:00:00

abstract：:Hypohidrosis predisposes to hyperthermia and may indicate generalized thermoregulatory failure. To assess the sweating capacity in human poikilothermia, we performed a quantitative analysis of the central and peripheral sudomotor pathways in four women with acquired poikilothermia (aged 29 to 38 years) and nine contro...

journal_title：Neurology

authors： MacKenzie MA,Schönbaum E,Hermus AR,Wollersheim HC,Thien T,Smals AG,Kloppenborg PW

更新日期：1995-08-01 00:00:00

abstract：OBJECTIVE:To report 5-year outcomes from the subthalamic nucleus (STN) deep brain stimulation (DBS) in early-stage Parkinson disease (PD) pilot clinical trial. METHODS:The pilot was a prospective, single-blind clinical trial that randomized patients with early-stage PD (Hoehn & Yahr II off medications) to receive bila...

journal_title：Neurology

authors： Hacker ML,Turchan M,Heusinkveld LE,Currie AD,Millan SH,Molinari AL,Konrad PE,Davis TL,Phibbs FT,Hedera P,Cannard KR,Wang L,Charles D

更新日期：2020-07-28 00:00:00

abstract：OBJECTIVE:To investigate whether quantitative MR techniques can be used to distinguish between mesial temporal sclerosis in patients with a history of prolonged febrile convulsion and in patients without such a history. METHODS:Quantitative hippocampal T2 relaxometry, hippocampal volumetry, and single voxel (1)H-MRS d...

journal_title：Neurology

authors： Scott RC,Gadian DG,Cross JH,Wood SJ,Neville BG,Connelly A

更新日期：2001-06-26 00:00:00

abstract：:We studied the effect of deep brain stimulation (DBS) of the ventral intermediate thalamic nucleus on voice symptoms in seven patients with essential tremor. All had undergone DBS for management of hand tremor. Five of the patients had received unilateral implants; two were treated bilaterally. Each reported improveme...

journal_title：Neurology

authors： Carpenter MA,Pahwa R,Miyawaki KL,Wilkinson SB,Searl JP,Koller WC

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:To assess whether exon deletions or duplications in CLCN1 are associated with recessive myotonia congenita (MC). METHODS:We performed detailed clinical and electrophysiologic characterization in 60 patients with phenotypes consistent with MC. DNA sequencing of CLCN1 followed by multiplex ligation-dependent p...

journal_title：Neurology

authors： Raja Rayan DL,Haworth A,Sud R,Matthews E,Fialho D,Burge J,Portaro S,Schorge S,Tuin K,Lunt P,McEntagart M,Toscano A,Davis MB,Hanna MG

更新日期：2012-06-12 00:00:00

abstract：:Call-Fleming syndrome is a reversible segmental vasoconstriction of cerebral arteries manifested by a "thunderclap" headache and focal neurologic symptoms. Although of unknown etiology, it has been reported in association with vasoactive sympathomimetic drugs. The authors report Call-Fleming syndrome in two patients w...

journal_title：Neurology

authors： Noskin O,Jafarimojarrad E,Libman RB,Nelson JL

更新日期：2006-07-11 00:00:00

abstract：OBJECTIVE:Gingival overgrowth is an important adverse effect of phenytoin (PHT) therapy, occurring in about half of the patients. This study aimed to evaluate the effect of oral folic acid supplementation (0.5 mg/day) for the prevention of PHT-induced gingival overgrowth (PIGO) in children with epilepsy aged 6-15 years...

journal_title：Neurology

authors： Arya R,Gulati S,Kabra M,Sahu JK,Kalra V

更新日期：2011-04-12 00:00:00

abstract：:Patients with myotonic dystrophy often develop respiratory failure caused by alveolar hypoventilation. Abnormalities in the ventilatory response to hypoxia and hypercapnia may explain this phenomenon. Accordingly, hypoxic and hypercapnic responses were measured in seven patients with myotonic dystrophy who had only mi...

journal_title：Neurology

authors： Carroll JE,Zwillich CW,Weil JV

更新日期：1977-12-01 00:00:00

abstract：:Outcome after carpal tunnel surgery was studied retrospectively in 32 patients with peripheral neuropathy and carpal tunnel syndrome. Nocturnal paresthesias were almost universally relieved, followed in order of responsiveness by pain, numbness, and weakness. Twenty-five of 28 patients said they would have the surgery...

journal_title：Neurology

authors： Morgenlander JC,Lynch JR,Sanders DB

更新日期：1997-10-01 00:00:00

abstract：:To assess the role of current weekly alcohol consumption as a risk factor for cerebral infarction, we administered a pretested questionnaire to 205 middle-aged and elderly acute ischemic stroke patients and 410 outpatient controls matched by age, sex, race, and method of hospital payment. The frequency of hypertension...

journal_title：Neurology

authors： Gorelick PB,Rodin MB,Langenberg P,Hier DB,Costigan J

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVES:To quantify the quality of physicians' emergency first response to status epilepticus (SE) and to identify risk factors for nonadherence to treatment guidelines in a standardized simulated scenario. METHODS:In this prospective trial, 58 physicians (of different background) of the University Hospital Basel, ...

journal_title：Neurology

authors： Sutter R,Tisljar K,Opić P,De Marchis GM,Bassetti S,Bingisser R,Hunziker S,Marsch S

更新日期：2019-11-05 00:00:00

abstract：OBJECTIVE:To compare the efficacy, tolerability, and safety of IV methylprednisolone (IV MP) vs oral methylprednisolone (oMP) at equivalent high doses in patients with multiple sclerosis (MS) experiencing a recent relapse. METHODS:Patients with a clinical relapse within the previous 2 weeks and at least 1 gadolinium (...

journal_title：Neurology

authors： Martinelli V,Rocca MA,Annovazzi P,Pulizzi A,Rodegher M,Martinelli Boneschi F,Scotti R,Falini A,Sormani MP,Comi G,Filippi M

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:This study correlated the extent of abnormalities detected by different magnetic resonance imaging (MRI) techniques [proton density (PD)-weighted, T1-weighted, and magnetization transfer imaging (MTI)] with the overall cognitive, frontal lobe, and memory impairments in patients with MS. PATIENTS:There were 3...

journal_title：Neurology

authors： Rovaris M,Filippi M,Falautano M,Minicucci L,Rocca MA,Martinelli V,Comi G

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:To describe the clinical features, MRI findings, and pathogenesis of strokes producing internuclear ophthalmoplegia (INO) as an isolated or predominant clinical manifestation. METHODS:Thirty patients presenting with INO without (n = 12) or with (n = 18) minimal other neurologic signs were studied. MRI and an...

journal_title：Neurology

authors： Kim JS

更新日期：2004-05-11 00:00:00

abstract：:Cytokines such as interleukin-1 and tumor necrosis factor are involved in the triggering of the immune response, induction of acute inflammatory events, and transition to, or persistence of, chronic inflammation. The action of proinflammatory cytokines is regulated by their receptor expression, downregulation and shed...

journal_title：Neurology

authors： Burger D,Dayer JM

更新日期：1995-06-01 00:00:00

abstract：:Using data from the compulsory Medical Birth Registry of Norway, the authors investigated the effect of maternal multiple sclerosis (MS) on pregnancy, delivery, and birth outcome in 649 births by MS mothers and 2.1 million control births. The mothers with MS had a higher proportion of neonates small for gestational ag...

journal_title：Neurology

authors： Dahl J,Myhr KM,Daltveit AK,Hoff JM,Gilhus NE

更新日期：2005-12-27 00:00:00

abstract：:Using a perceptual technique it is shown that patients with chronic external ophthalmoplegia have shortened vestibular responses. It is postulated that this is secondary to the retinal image slip experienced by these patients during head movements and a useful compensatory mechanism to suppress motion-induced sickness...

journal_title：Neurology

authors： Grunfeld EA,Shallo-Hoffmann JA,Cassidy L,Okada T,Faldon M,Acheson JF,Bronstein AM

更新日期：2003-06-24 00:00:00

abstract：:As the substantia nigra degenerates in Parkinson's disease (PD), the nigrostriatal pathway is disrupted, reducing striatal dopamine and producing PD symptoms. Although dopamine does not readily cross the blood-brain barrier, its precursor, levodopa, does. Levodopa is absorbed in the small bowel and is rapidly cataboli...

journal_title：Neurology

authors： Koller WC,Rueda MG

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:To construct a grading score that predicts neurologic function 1 year after diagnosis of anti-NMDA receptor (NMDAR) encephalitis. METHODS:Three hundred eighty-two patients with detailed information and functional status at 1 year were studied. Factors associated with poor status (defined as modified Rankin S...

journal_title：Neurology

authors： Balu R,McCracken L,Lancaster E,Graus F,Dalmau J,Titulaer MJ

更新日期：2019-01-15 00:00:00

abstract：OBJECTIVE:Glatiramer acetate (formerly known as copolymer 1) is the major noninterferon immunomodulatory agent used in the treatment of relapsing-remitting multiple sclerosis. Its mechanism of action over the past 40 years has evolved with our understanding of the immune response. METHODS:We review the various mechani...

journal_title：Neurology

authors： Racke MK,Lovett-Racke AE,Karandikar NJ

更新日期：2010-01-05 00:00:00

abstract：OBJECTIVE:It is known that muscle phosphorylase deficiency restricts carbohydrate utilization, but the implications for muscle fat metabolism have not been studied. We questioned whether patients with McArdle disease can compensate for the blocked muscle glycogen breakdown by enhancing fat oxidation during exercise. M...

journal_title：Neurology

authors： Ørngreen MC,Jeppesen TD,Andersen ST,Taivassalo T,Hauerslev S,Preisler N,Haller RG,van Hall G,Vissing J

更新日期：2009-02-24 00:00:00

abstract：:A 33-year-old man with untreated hypertension had sudden onset of signs and symptoms suggestive of a dorsal lateral medullary syndrome. He died after 27 days. Postmortem studies revealed intramedullary hemorrhage with extension into the fourth ventricle and hypertensive cardiovascular disease. ...

journal_title：Neurology

authors： Neumann PE,Mehler MF,Horoupian DS

更新日期：1985-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the usefulness of ocular motor information in the early diagnosis of corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP). METHODS:Seven PSP patients, six CBD patients, and three atypical CBD patients were followed longitudinally with repeated electrooculographic (EOG) recordi...

journal_title：Neurology

authors： Rivaud-Péchoux S,Vidailhet M,Gallouedec G,Litvan I,Gaymard B,Pierrot-Deseilligny C

更新日期：2000-03-14 00:00:00

abstract：OBJECTIVE:The aim of this study was to apply the HIV-associated neurocognitive disorders (HAND) criteria for diagnosing HAND in HIV-infected adults, in a cohort of HIV-infected youth to thus establish whether this system is able to detect a spectrum of neurocognitive disorders (ND) in HIV-infected youth. METHODS:We us...

journal_title：Neurology

authors： Hoare J,Phillips N,Joska JA,Paul R,Donald KA,Stein DJ,Thomas KG

更新日期：2016-07-05 00:00:00