Transient ischemic attacks: a prospective study of 225 patients.

abstract：OBJECTIVES:To survey US physicians involved in acute stroke care to determine the proportion of hospitals that currently meet the recommended Brain Attack Coalition (BAC) criteria for Primary Stroke Centers (PSC) and obtain opinions regarding the value of stroke centers. METHODS:A survey regarding the BAC guidelines f...

journal_title：Neurology

authors： Kidwell CS,Shephard T,Tonn S,Lawyer B,Murdock M,Koroshetz W,Alberts M,Hademenos GJ,Saver JL

更新日期：2003-05-13 00:00:00

abstract：BACKGROUND:The topodiagnostic value and specificity of nystagmus in patients with mesencephalic lesions and its relation to tonic torsional deficits and vertical saccade deficits is controversial and anecdotal. METHODS:The authors examined 11 patients with vascular MRI-identified mesencephalic lesions and clinical evi...

journal_title：Neurology

authors： Helmchen C,Rambold H,Kempermann U,Büttner-Ennever JA,Büttner U

更新日期：2002-12-24 00:00:00

abstract：:Functional brain imaging has been a standard tool in the basic and clinical neurosciences for at least 2 decades, and structural brain imaging can claim an even longer track record of successful use for diagnosis of neurodegenerative disease. It is instructive to recall the ways in which brain imaging has been used to...

journal_title：Neurology

authors： Habeck C,Whitwell JL

更新日期：2013-01-08 00:00:00

abstract：OBJECTIVE:To describe the clinical features, MRI findings, and pathogenesis of strokes producing internuclear ophthalmoplegia (INO) as an isolated or predominant clinical manifestation. METHODS:Thirty patients presenting with INO without (n = 12) or with (n = 18) minimal other neurologic signs were studied. MRI and an...

journal_title：Neurology

authors： Kim JS

更新日期：2004-05-11 00:00:00

abstract：:The electronic medical record (EMR) is changing the landscape of medical practice in the modern age. Increasing emphasis on quality metric reporting, data-driven documentation, and timely coding and billing are pressuring institutions across the country to adopt the latest EMR technology. The impact of these systems o...

journal_title：Neurology

authors： Strowd RE 3rd

更新日期：2014-09-23 00:00:00

abstract：OBJECTIVE:To assess cortical inhibitory and excitatory mechanisms in obsessive-compulsive disorder (OCD). BACKGROUND:Transcranial magnetic stimulation (TMS) studies have found decreased neuronal inhibition and a reduced cortical silent period in the primary motor area in Tourette's syndrome, focal dystonia, and other ...

journal_title：Neurology

authors： Greenberg BD,Ziemann U,Corá-Locatelli G,Harmon A,Murphy DL,Keel JC,Wassermann EM

更新日期：2000-01-11 00:00:00

abstract：BACKGROUND/OBJECTIVE:Neglect has been attributed to sensory-attentional, motor-intentional, and representational disorders. Although patients with neglect may have defective visual exploration, the nature of this exploration deficit has not been entirely elucidated. The purpose of this study is to learn how, compared w...

journal_title：Neurology

authors： Kim M,Anderson JM,Heilman KM

更新日期：1997-10-01 00:00:00

abstract：:A neurocutaneous syndrome is described in which spastic paraplegia, peroneal neuropathy, and crural hypopigmentation are inherited in a dominant pattern. Spastic paraplegia becomes clinically apparent during adolescence or in childhood and progresses slowly throughout the adult years with a variability in severity of ...

journal_title：Neurology

authors： Stewart RM,Tunell G,Ehle A

更新日期：1981-06-01 00:00:00

abstract：:Stuttering is an action-induced speech disorder with involuntary, audible, or silent repetitions or prolongations in the utterance of short speech elements (sounds, syllables) and words. Symptomatic treatment programs frequently have initial success; persistent benefit is variable and many patients remain disabled. St...

journal_title：Neurology

authors： Brin MF,Stewart C,Blitzer A,Diamond B

更新日期：1994-12-01 00:00:00

abstract：:All but 6% of the subjects with relapsing remitting MS who were randomly assigned to receive glatiramer acetate or placebo for the 9-month controlled phase of the European/Canadian MRI trial entered an open-label extension with quarterly clinical and MRI evaluations for another 9 months. There was a 54% reduction in t...

journal_title：Neurology

authors： Wolinsky JS,Comi G,Filippi M,Ladkani D,Kadosh S,Shifroni G,European\/Canadian Glatiramer Acetate Study Group.

更新日期：2002-10-22 00:00:00

abstract：OBJECTIVE:Quality of neurologic emergency management in an under-resourced country may be improved by standard operating procedures (SOPs). METHODS:Neurologic SOPs were implemented in a large urban (Banjul) and a small rural (Brikama) hospital in the Gambia. As quality indicators of neurologic emergency management, pe...

journal_title：Neurology

authors： Jaiteh LES,Helwig SA,Jagne A,Ragoschke-Schumm A,Sarr C,Walter S,Lesmeister M,Manitz M,Blaß S,Weis S,Schlund V,Bah N,Kauffmann J,Fousse M,Kangankan S,Ramos Cabrera A,Kronfeld K,Ruckes C,Liu Y,Nyan O,Fassbender K

更新日期：2017-07-11 00:00:00

abstract：:Butyrylcholinesterase is implicated in the pathology of AD. Selective inhibitors increase acetylcholine and improve cognitive function in animal models. In dementia with Lewy bodies, cholinergic activities are more affected than in AD. The authors report a highly significant association between temporal cortex butyryl...

journal_title：Neurology

authors： Perry E,McKeith I,Ballard C

更新日期：2003-06-10 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of yoga as an adjuvant to conventional medical management on clinical outcomes in patients with migraine. METHODS:CONTAIN was a prospective, randomized, open-label superiority trial with blinded endpoint assessment carried out at a single tertiary care academic hospital in New D...

journal_title：Neurology

authors： Kumar A,Bhatia R,Sharma G,Dhanlika D,Vishnubhatla S,Singh RK,Dash D,Tripathi M,Srivastava MVP

更新日期：2020-05-26 00:00:00

abstract：OBJECTIVE:To clarify the genetic, clinicopathologic, and neuroimaging characteristics of patients with hereditary diffuse leukoencephalopathy with spheroids (HDLS) with the colony stimulating factor 1 receptor (CSF-1R) mutation. METHODS:We performed molecular genetic analysis of CSF-1R in patients with HDLS. Detailed ...

journal_title：Neurology

authors： Konno T,Tada M,Tada M,Koyama A,Nozaki H,Harigaya Y,Nishimiya J,Matsunaga A,Yoshikura N,Ishihara K,Arakawa M,Isami A,Okazaki K,Yokoo H,Itoh K,Yoneda M,Kawamura M,Inuzuka T,Takahashi H,Nishizawa M,Onodera O,Kakita

更新日期：2014-01-14 00:00:00

abstract：:Previous reports and the Physicians' Desk Reference caution against the use of levodopa in Parkinson's disease (PD) patients with melanoma. A critical review of the literature reveals only anecdotal evidence to support a link between levodopa and melanoma. In fact, levodopa has an antitumor effect on melanoma. We repo...

journal_title：Neurology

authors： Weiner WJ,Singer C,Sanchez-Ramos JR,Goldenberg JN

更新日期：1993-04-01 00:00:00

abstract：:Since the introduction of computed tomography (CT), there have been numerous reports of brain abscess treated successfully without surgery. Because pathologic confirmation was lacking in these patients, diagnosis was based on CT abnormalities, usually ring enhancement. However, our recent clinical experience and the e...

journal_title：Neurology

authors： Dobkin JF,Healton EB,Dickinson PC,Brust JC

更新日期：1984-02-01 00:00:00

abstract：:The neurofilament is the major cytoskeletal structure of myelinated axons. In this study, CSF levels of the light subunit of the neurofilament protein (NFL) were increased in patients with vascular dementia (VAD), AD, and frontotemporal dementia (FTD) compared with neurologically healthy individuals. Because NFL is lo...

journal_title：Neurology

authors： Rosengren LE,Karlsson JE,Sjögren M,Blennow K,Wallin A

更新日期：1999-03-23 00:00:00

abstract：:The presence of the APOE epsilon 4 allele encoding apolipoprotein E4 (apoE4) is the major genetic risk factor for late-onset Alzheimer's disease (AD). However, the molecular and cellular mechanisms by which APOE epsilon 4 renders AD risk are unclear. In this report, we present genetic evidence that an apoE receptor, L...

journal_title：Neurology

authors： Kang DE,Saitoh T,Chen X,Xia Y,Masliah E,Hansen LA,Thomas RG,Thal LJ,Katzman R

更新日期：1997-07-01 00:00:00

abstract：OBJECTIVE:To investigate clinical and economic consequences following generic substitution of one vs multiple generics of topiramate (Topamax; Ortho-McNeil Neurologics, Titusville, NJ). METHODS:Medical and pharmacy claims data of Régie de l'Assurance-Maladie du Québec from January 2006 to October 2007 were used. Patie...

journal_title：Neurology

authors： Duh MS,Paradis PE,Latrémouille-Viau D,Greenberg PE,Lee SP,Durkin MB,Wan GJ,Rupnow MF,LeLorier J

更新日期：2009-06-16 00:00:00

abstract：:We used [18F]-2-fluoro-2-deoxy-D-glucose (FDG) and PET to study regional cerebral glucose utilization in seven patients with fatal familial insomnia (FFI), an inherited prion disease with a mutation at codon 178 of the prion protein gene. Four patients were methionine/methionine homozygotes at codon 129 (symptom durat...

journal_title：Neurology

authors： Cortelli P,Perani D,Parchi P,Grassi F,Montagna P,De Martin M,Castellani R,Tinuper P,Gambetti P,Lugaresi E,Fazio F

更新日期：1997-07-01 00:00:00

abstract：OBJECTIVE:To examine the role of mutations in GABRB3 encoding the β3 subunit of the GABAA receptor in individual patients with epilepsy with regard to causality, the spectrum of genetic variants, their pathophysiology, and associated phenotypes. METHODS:We performed massive parallel sequencing of GABRB3 in 416 patient...

journal_title：Neurology

authors： Møller RS,Wuttke TV,Helbig I,Marini C,Johannesen KM,Brilstra EH,Vaher U,Borggraefe I,Talvik I,Talvik T,Kluger G,Francois LL,Lesca G,de Bellescize J,Blichfeldt S,Chatron N,Holert N,Jacobs J,Swinkels M,Betzler C,Syr

更新日期：2017-01-31 00:00:00

abstract：:Arm-diaphragm synkinesis may occur after injury to the proximal portion of the brachial plexus or cervical nerve roots. Regenerating axons of phrenic motor neurons are misdirected to supply limb muscles. Electrodiagnostic investigations of three patients with symptoms referable to upper brachial plexus or cervical roo...

journal_title：Neurology

authors： Swift TR,Leshner RT,Gross JA

更新日期：1980-04-01 00:00:00

abstract：OBJECTIVES:To investigate the role of beta oscillations in urinary voiding and their association with lower urinary tract symptoms in Parkinson disease (PD). METHODS:We used surgically implanted deep brain stimulation electrodes to record local field potential signals from the subthalamic nucleus (STN) and globus pall...

journal_title：Neurology

authors： Roy HA,Aziz TZ,Fitzgerald JJ,Green AL

更新日期：2018-04-24 00:00:00

abstract：OBJECTIVE:To identify independent predictors of clinical or cerebral lesion progression in a large sample of adult patients with moyamoya angiopathy (MMA) prior to decisions regarding revascularization surgery. METHODS:Ninety participants (median age, 37.5 years) were assessed at baseline and followed for a median tim...

journal_title：Neurology

authors： Hervé D,Ibos-Augé N,Calvière L,Rogan C,Labeyrie MA,Guichard JP,Godin O,Kossorotoff M,Habert MO,Lasserve ET,Chevret S,Chabriat H

更新日期：2019-07-23 00:00:00

abstract：:The mechanism by which prednisone improves muscle strength and function in Duchenne muscular dystrophy (DMD) is unknown. We addressed the possibility that clinical improvement was related to prednisone-induced alterations in skeletal muscle dystrophin. We performed muscle biopsies on patients at the conclusion of a ra...

journal_title：Neurology

authors： Burrow KL,Coovert DD,Klein CJ,Bulman DE,Kissel JT,Rammohan KW,Burghes AH,Mendell JR

更新日期：1991-05-01 00:00:00

abstract：:Videotape analysis of 76 attacks in 14 epileptics showed two electro-clinical types of psychomotor attacks. The first and most common type had three clinical phases, consisting of an initial motionless stare, stereotyped movements, and reactive automatisms during impaired consciousness. The second and less common type...

journal_title：Neurology

authors： Escueta AV,Kunze U,Waddell G,Boxley J,Nadel A

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:Plasma exchange (PE) is used to treat severe episodes of CNS demyelination unresponsive to corticosteroids. Predictors of long-term response are not well known. METHODS:We retrospectively reviewed the medical records of 41 patients consecutively treated by PE between January 1995 and July 2007. The primary ...

journal_title：Neurology

authors： Llufriu S,Castillo J,Blanco Y,Ramió-Torrentà L,Río J,Vallès M,Lozano M,Castellà MD,Calabia J,Horga A,Graus F,Montalban X,Saiz A

更新日期：2009-09-22 00:00:00

abstract：:The minimum exposure to estrogen required to cause estrogen-withdrawal migraine has been studied by giving long-acting estradiol valerate to four women and short-acting estradiol benzoate to two women. It was found that several days of exposure to high estrogen levels were needed to cause migraine on estrogen withdraw...

journal_title：Neurology

authors： Somerville BW

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND:Microvascular brain injury, typically measured by extent of white matter hyperintensity (WMH) on MRI, is an important contributor to cognitive impairment in the elderly. Recent studies suggest a role for circulating beta-amyloid peptide in microvascular dysfunction and white matter disease. METHODS:The auth...

journal_title：Neurology

authors： Gurol ME,Irizarry MC,Smith EE,Raju S,Diaz-Arrastia R,Bottiglieri T,Rosand J,Growdon JH,Greenberg SM

更新日期：2006-01-10 00:00:00

abstract：:Epilepsy surgery is a well-established treatment for certain types of intractable epilepsy. While there is a relatively high number of epilepsy surgery centers in Canada and the United States, the same cannot be said about many other parts of the world, such as South America. Although there are notable exceptions, suc...

journal_title：Neurology

authors： Steven DA,Vasquez CM,Delgado JC,Zapata-Luyo W,Becerra A,Barreto E,Arango MF,Burneo JG

更新日期：2018-08-21 00:00:00