Cerebral organization of affect suggested by temporal lobe seizures.

Abstract:

:A right-handed woman with independent left- and right-sided temporal lobe discharges was studied by continuous EEG and videotape monitoring for 3 weeks. Changes in affect were noted in the immediate and extended postictal periods and varied with the side of discharge. After a left-sided discharge, she became globally aphasic and depressed. Right-sided discharges evoked laughing and postictal hypomania. These manifestations were attributed to contralateral hemispheric disinhibition after ipsilateral seizure inactivation. This case provides evidence that the speech-dominant hemisphere subserves positive feelings and the nondominant hemisphere negative ones.

journal_name

Neurology

journal_title

Neurology

authors

Hurwitz TA,Wada JA,Kosaka BD,Strauss EH

doi

10.1212/wnl.35.9.1335

subject

Has Abstract

pub_date

1985-09-01 00:00:00

pages

1335-7

issue

9

eissn

0028-3878

issn

1526-632X

journal_volume

35

pub_type

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